Details for gene set V$SREBP1

Table: GSEA Results Summary

Dataset	Set_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls #wtNotch_versus_truncNotch.phenotype_truncNotch_versus_wtNotch.cls #wtNotch_versus_truncNotch_repos
Phenotype	phenotype_truncNotch_versus_wtNotch.cls#wtNotch_versus_truncNotch_repos
Upregulated in class	truncNotch
GeneSet	V$SREBP1_Q6
Enrichment Score (ES)	-0.41927022
Normalized Enrichment Score (NES)	-1.2294226
Nominal p-value	0.07122507
FDR q-value	1.0
FWER p-Value	1.0

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	KPNB1	1690138	110	2.828	0.0213	No
2	FCHSD2	5720092	167	2.628	0.0436	No
3	NMT1	5810152	280	2.373	0.0604	No
4	PDCD10	4760500	360	2.201	0.0773	No
5	PIAS1	5340301	607	1.854	0.0818	No
6	NSF	4070075	1009	1.418	0.0737	No
7	ATP6V1A	6590242	1103	1.330	0.0815	No
8	EMP1	4120438	1189	1.248	0.0889	No
9	SLIT3	7100132	1496	1.016	0.0821	No
10	NFIX	2450152	1564	0.991	0.0880	No
11	ZFYVE1	60440	1606	0.973	0.0952	No
12	MMP14	670079	1620	0.964	0.1038	No
13	SIPA1L2	4850731	1664	0.930	0.1104	No
14	ANP32A	510044 1580095 2680037	1686	0.919	0.1181	No
15	EIF4G2	3800575 6860184	1689	0.918	0.1269	No
16	NFAT5	2510411 5890195 6550152	1871	0.804	0.1248	No
17	PPP1R10	110136 3170725 3610484	2113	0.666	0.1182	No
18	MYH10	2640673	2217	0.614	0.1185	No
19	YWHAQ	6760524	2432	0.532	0.1120	No
20	PHF15	6550066 6860673	2460	0.519	0.1155	No
21	LASP1	1690528 2190341 6420341	2487	0.511	0.1190	No
22	DDX6	2630025 6770408	2488	0.510	0.1240	No
23	STX1A	3060273	2552	0.487	0.1252	No
24	TRERF1	6370017 6940138	2557	0.485	0.1297	No
25	NTRK3	4050687 4070167 4610026 6100484	2582	0.477	0.1330	No
26	JUP	2510671	2691	0.443	0.1314	No
27	FXYD1	1400239 6560129	2700	0.440	0.1352	No
28	DYRK1A	3190181	2750	0.423	0.1366	No
29	EN1	5360168 7050025	2821	0.400	0.1367	No
30	PACSIN3	4540369 4540400 5360037 6940129	2921	0.367	0.1349	No
31	PCF11	1240180	2964	0.353	0.1360	No
32	B4GALT2	780037	3025	0.333	0.1359	No
33	GPR85	5130750 5910020	3044	0.327	0.1381	No
34	SLC39A14	670300 1400093 1990711	3188	0.288	0.1331	No
35	REL	360707	3244	0.279	0.1328	No
36	ZIC4	1500082	3339	0.256	0.1302	No
37	MAPKAPK3	630520	3357	0.253	0.1317	No
38	FBS1	2570520	3463	0.231	0.1283	No
39	BAZ2A	730184	3493	0.226	0.1289	No
40	CLDN5	6510717	3523	0.218	0.1294	No
41	CLASP1	6860279	3529	0.218	0.1312	No
42	SOX12	1780037	3946	0.154	0.1102	No
43	ENO2	2320068	4140	0.133	0.1010	No
44	RBX1	2120010 2340047	4144	0.132	0.1021	No
45	DSG4	3990605 6400736	4206	0.127	0.1000	No
46	POU4F2	2120195 2570022	4242	0.124	0.0993	No
47	LRP8	3610746 5360035	4248	0.123	0.1002	No
48	RARG	6760136	4350	0.114	0.0958	No
49	TRAF4	3060041 4920528 6980286	4421	0.107	0.0931	No
50	SREBF2	3390692	4567	0.098	0.0862	No
51	KIF1B	1240494 2370139 4570270 6510102	4651	0.092	0.0825	No
52	TEAD2	6450079	4910	0.077	0.0693	No
53	DHH	2120433	5002	0.073	0.0651	No
54	MEOX2	6400288	5046	0.071	0.0634	No
55	KCNN3	6520600 6420138	5078	0.069	0.0624	No
56	CACNA1D	1740315 4730731	5172	0.065	0.0580	No
57	SLC4A10	2060670	5543	0.051	0.0384	No
58	LIN28	6590672	5814	0.042	0.0242	No
59	SLC24A1	1240463	5832	0.042	0.0237	No
60	GUCA2B	4200014	5876	0.040	0.0217	No
61	TCF2	870338 5050632	5933	0.039	0.0190	No
62	GAP43	3130504	5951	0.038	0.0185	No
63	GRIA1	1340152 3780750 4920440	5952	0.038	0.0189	No
64	GFAP	2060092	6081	0.035	0.0123	No
65	GRID2	2680242	6119	0.034	0.0106	No
66	SLC4A1	6290577	6305	0.030	0.0008	No
67	DUSP8	6650039	6341	0.029	-0.0008	No
68	EMX2	1660092	6383	0.028	-0.0028	No
69	SERPINI1	2940468	6397	0.028	-0.0032	No
70	SIX4	6760022	6435	0.027	-0.0049	No
71	HYAL1	3850341	6566	0.024	-0.0118	No
72	PLA2G3	5130739	6681	0.021	-0.0177	No
73	GNAO1	2510292 6590487	6769	0.020	-0.0223	No
74	CACNB1	2940427 3710487	6937	0.016	-0.0312	No
75	SALL1	5420020 7050195	6955	0.016	-0.0319	No
76	SLC2A4	540441	7047	0.014	-0.0367	No
77	PAX3	50551	7369	0.009	-0.0541	No
78	ZFP36L1	2510138 4120048	7959	-0.001	-0.0860	No
79	HOXD10	6100039	8242	-0.006	-0.1012	No
80	KCNMB1	4760139	8306	-0.006	-0.1046	No
81	ESR1	4060372 5860193	8512	-0.010	-0.1156	No
82	ANXA9	1190195	8621	-0.012	-0.1213	No
83	PDE5A	130072	8804	-0.015	-0.1311	No
84	LRRN1	3290154	8817	-0.015	-0.1316	No
85	TIMP4	6110433	8892	-0.016	-0.1354	No
86	NF1	6980433	8913	-0.017	-0.1363	No
87	EVX1	1980471	9102	-0.020	-0.1464	No
88	NFATC4	2470735	9158	-0.021	-0.1491	No
89	FABP6	7000278	9231	-0.022	-0.1528	No
90	LMX1A	2810239 5690324	9374	-0.025	-0.1603	No
91	GREM1	3940180	9722	-0.030	-0.1788	No
92	HOXA11	6980133	9753	-0.031	-0.1801	No
93	HIF1A	5670605	9786	-0.032	-0.1816	No
94	FBXO24	1230132 4610121	9861	-0.033	-0.1853	No
95	ERF	110551 1770278	10004	-0.036	-0.1926	No
96	HOXC4	1940193	10070	-0.038	-0.1958	No
97	RKHD3	6180471	10681	-0.051	-0.2284	No
98	FADS3	3120079	11080	-0.061	-0.2494	No
99	CRLF1	3520092	11152	-0.062	-0.2526	No
100	PTRF	2260204	11182	-0.063	-0.2536	No
101	PKP3	3710048	11313	-0.067	-0.2600	No
102	ATP6V0C	1780609	11554	-0.075	-0.2723	No
103	AGER	5860538 5910180	11582	-0.075	-0.2730	No
104	EPO	940180	11661	-0.078	-0.2765	No
105	KCNK7	4230576	11717	-0.080	-0.2787	No
106	MT4	4780338	11785	-0.083	-0.2815	No
107	DLGAP4	4570672 5690161	11817	-0.083	-0.2824	No
108	MACF1	1340132 2370176 2900750 6590364	11913	-0.087	-0.2867	No
109	NEUROD2	5290097	11941	-0.088	-0.2873	No
110	FLNC	2360048 5050270	11965	-0.089	-0.2877	No
111	SMTN	670563 1190438	12041	-0.092	-0.2909	No
112	LGP2	4480338	12171	-0.097	-0.2970	No
113	DPYSL2	2100427 3130112 5700324	12475	-0.112	-0.3123	No
114	KLF12	1660095 4810288 5340546 6520286	12544	-0.115	-0.3149	No
115	HOXA3	3610632 6020358	12646	-0.121	-0.3192	No
116	BCL6B	60047	12648	-0.121	-0.3181	No
117	H2AFY	4730750	13017	-0.143	-0.3367	No
118	INPP4A	510215 1090541 4850093 6100519	13239	-0.159	-0.3471	No
119	TGFB1I1	2060288 6550450	13285	-0.163	-0.3480	No
120	LRCH4	5220279 6510026	13501	-0.181	-0.3579	No
121	ABCG4	3440458	13590	-0.189	-0.3608	No
122	HOXB2	6450592	13804	-0.210	-0.3704	No
123	LDLR	5670386	13884	-0.218	-0.3726	No
124	ATE1	290491 6940722	13937	-0.224	-0.3732	No
125	PLCB3	4670402	13955	-0.227	-0.3720	No
126	SYTL2	580097 5390576 6770603	14095	-0.241	-0.3772	No
127	NRGN	4280433	14115	-0.244	-0.3759	No
128	A2BP1	2370390 4590593 5550014	14302	-0.269	-0.3834	No
129	LPHN1	1400113 3130301	14510	-0.301	-0.3917	No
130	IMPDH2	5220138	14567	-0.313	-0.3917	No
131	NR1D1	2360471 770746 6590204	14570	-0.313	-0.3888	No
132	TBCC	4810021	14588	-0.315	-0.3867	No
133	MAP1A	4920576	14671	-0.329	-0.3879	No
134	RPS10	4560673	14731	-0.341	-0.3879	No
135	SLCO3A1	1050408 2370156 6110072	14869	-0.363	-0.3918	No
136	DDR1	2060044 5220180	15087	-0.411	-0.3996	No
137	PDGFB	3060440 6370008	15107	-0.414	-0.3966	No
138	TCF1	5390022	15199	-0.435	-0.3974	No
139	PVRL1	2570167 5220519 5890500 3190309	15271	-0.452	-0.3969	No
140	LBX1	1300164 4060204	15292	-0.457	-0.3936	No
141	AP1G2	780458 2690068	15309	-0.461	-0.3900	No
142	CLSTN3	2350685	15330	-0.468	-0.3866	No
143	SYNPO2L	5390719	15505	-0.523	-0.3910	No
144	RAB10	2360008 5890020	15725	-0.603	-0.3970	No
145	ITPR3	4010632	15789	-0.624	-0.3944	No
146	SPI1	1410397	16074	-0.748	-0.4026	No
147	DLK1	1240138	16382	-0.888	-0.4107	Yes
148	CDC42EP4	4150338	16392	-0.891	-0.4026	Yes
149	CLIC1	110600	16583	-0.981	-0.4035	Yes
150	TYRO3	3130193	16609	-0.993	-0.3953	Yes
151	IMMT	870450 4280438	16611	-0.993	-0.3857	Yes
152	PDXP	5050204 460273 6040102	16625	-0.996	-0.3768	Yes
153	RHOA	580142 5900131 5340450	16637	-0.998	-0.3678	Yes
154	HSPG2	2510687 6220750	16727	-1.032	-0.3627	Yes
155	STAT6	1190010 5720019	16806	-1.075	-0.3566	Yes
156	SSBP2	2260725 2900400 4730711	16927	-1.151	-0.3520	Yes
157	ARHGDIB	4730433	17043	-1.226	-0.3464	Yes
158	PEX16	4560044	17119	-1.267	-0.3383	Yes
159	NDRG2	450403	17220	-1.340	-0.3308	Yes
160	MTMR3	1050014 4920180	17231	-1.344	-0.3184	Yes
161	FOXP4	6290022	17276	-1.373	-0.3075	Yes
162	DCTN1	1450056 6590022	17321	-1.405	-0.2964	Yes
163	DNMT3B	2320138 4070059	17436	-1.482	-0.2883	Yes
164	MRPS18B	5570086	17927	-1.922	-0.2963	Yes
165	GRWD1	6350528	17999	-2.004	-0.2808	Yes
166	MYL6	60563 6100152	18078	-2.094	-0.2649	Yes
167	ARFIP2	1850301 4670180	18215	-2.274	-0.2503	Yes
168	FXC1	3710053 4060575	18400	-2.661	-0.2347	Yes
169	RHEBL1	2810576	18423	-2.741	-0.2095	Yes
170	CEBPB	2970019	18441	-2.781	-0.1836	Yes
171	DTX1	5900372	18461	-2.857	-0.1571	Yes
172	RHOG	6760575	18532	-3.188	-0.1302	Yes
173	ETV5	110017	18559	-3.357	-0.0992	Yes
174	CORO1A	3140609 3190020 3190037	18569	-3.439	-0.0666	Yes
175	PTK2B	4730411	18576	-3.507	-0.0331	Yes
176	GNAS	630441 1850373 4050152	18584	-3.653	0.0017	Yes