Dataset | Set_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls #wtNotch_versus_truncNotch.phenotype_truncNotch_versus_wtNotch.cls #wtNotch_versus_truncNotch_repos |
Phenotype | phenotype_truncNotch_versus_wtNotch.cls#wtNotch_versus_truncNotch_repos |
Upregulated in class | truncNotch |
GeneSet | V$PEA3_Q6 |
Enrichment Score (ES) | -0.48566884 |
Normalized Enrichment Score (NES) | -1.412363 |
Nominal p-value | 0.0028776978 |
FDR q-value | 0.86259794 |
FWER p-Value | 0.998 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | TRIM8 | 6130441 | 294 | 2.332 | 0.0036 | No | ||
2 | PRKACB | 4210170 | 339 | 2.235 | 0.0200 | No | ||
3 | CD84 | 1780168 | 600 | 1.860 | 0.0215 | No | ||
4 | INPPL1 | 110717 3120164 | 717 | 1.732 | 0.0297 | No | ||
5 | PTPRC | 130402 5290148 | 788 | 1.663 | 0.0399 | No | ||
6 | LRMP | 6290193 | 884 | 1.558 | 0.0478 | No | ||
7 | TMEM24 | 5860039 | 1125 | 1.314 | 0.0458 | No | ||
8 | FLI1 | 3990142 | 1167 | 1.266 | 0.0542 | No | ||
9 | NT5C2 | 4280735 4670528 | 1206 | 1.236 | 0.0625 | No | ||
10 | DCLRE1C | 1450041 2360091 3290671 3390739 | 1325 | 1.134 | 0.0657 | No | ||
11 | ARF3 | 3710446 | 1628 | 0.959 | 0.0573 | No | ||
12 | CDC14A | 4050132 | 1639 | 0.950 | 0.0648 | No | ||
13 | MR1 | 3850037 | 1681 | 0.922 | 0.0703 | No | ||
14 | TRIM33 | 580619 2230280 3990433 6200747 | 1746 | 0.879 | 0.0742 | No | ||
15 | SEC24C | 6980707 | 1761 | 0.869 | 0.0807 | No | ||
16 | GATA3 | 6130068 | 1785 | 0.855 | 0.0866 | No | ||
17 | SPATA6 | 4590373 | 1882 | 0.797 | 0.0881 | No | ||
18 | EXTL2 | 5050433 | 2048 | 0.690 | 0.0850 | No | ||
19 | MARK2 | 7210608 | 2090 | 0.675 | 0.0884 | No | ||
20 | TNFRSF19L | 1170168 1190358 5670270 | 2140 | 0.650 | 0.0912 | No | ||
21 | LZTS2 | 2260440 | 2173 | 0.635 | 0.0948 | No | ||
22 | PUM1 | 6130500 | 2191 | 0.627 | 0.0991 | No | ||
23 | ZDHHC5 | 1690711 | 2257 | 0.598 | 0.1006 | No | ||
24 | SLC35C1 | 4540154 | 2260 | 0.598 | 0.1055 | No | ||
25 | VDAC2 | 7000215 | 2599 | 0.471 | 0.0912 | No | ||
26 | ABLIM1 | 580170 3710338 6520504 | 2619 | 0.466 | 0.0941 | No | ||
27 | ITPR2 | 5360128 | 2737 | 0.428 | 0.0913 | No | ||
28 | GTF2H1 | 2570746 2650148 | 2751 | 0.423 | 0.0941 | No | ||
29 | GFI1 | 730180 | 2907 | 0.371 | 0.0889 | No | ||
30 | IRAK4 | 5390156 6130594 | 2911 | 0.370 | 0.0918 | No | ||
31 | TCEB3 | 5890156 | 2914 | 0.368 | 0.0948 | No | ||
32 | SNCG | 3120725 | 3034 | 0.331 | 0.0911 | No | ||
33 | CD69 | 380167 4730088 | 3135 | 0.303 | 0.0882 | No | ||
34 | FEN1 | 1770541 | 3136 | 0.302 | 0.0908 | No | ||
35 | CTBP2 | 430309 3710079 | 3211 | 0.285 | 0.0891 | No | ||
36 | LAMC1 | 4730025 | 3306 | 0.264 | 0.0863 | No | ||
37 | CAMK1D | 1660100 2350309 | 3375 | 0.251 | 0.0847 | No | ||
38 | KCNAB2 | 4850315 | 3414 | 0.243 | 0.0847 | No | ||
39 | RIN1 | 510593 | 3421 | 0.241 | 0.0864 | No | ||
40 | PICALM | 1940280 | 3429 | 0.238 | 0.0880 | No | ||
41 | PAFAH2 | 3140451 5720593 6510014 | 3440 | 0.235 | 0.0894 | No | ||
42 | ANK3 | 1500161 2900435 4210154 6400100 | 3454 | 0.233 | 0.0907 | No | ||
43 | CBL | 6380068 | 3569 | 0.209 | 0.0862 | No | ||
44 | RAB39 | 430524 | 3754 | 0.181 | 0.0778 | No | ||
45 | SV2A | 1450039 5570685 | 4038 | 0.142 | 0.0636 | No | ||
46 | TIAL1 | 4150048 6510605 | 4813 | 0.082 | 0.0224 | No | ||
47 | HIPK1 | 110193 | 4934 | 0.076 | 0.0165 | No | ||
48 | SLC41A1 | 1230528 | 4935 | 0.076 | 0.0172 | No | ||
49 | CAPZA1 | 3140390 | 4951 | 0.075 | 0.0170 | No | ||
50 | GRIN2B | 3800333 | 4982 | 0.074 | 0.0160 | No | ||
51 | FUT11 | 6040692 | 5137 | 0.067 | 0.0082 | No | ||
52 | SPRR4 | 5720273 | 5401 | 0.056 | -0.0056 | No | ||
53 | ELK4 | 460494 940369 4480136 | 5556 | 0.051 | -0.0135 | No | ||
54 | LIN28 | 6590672 | 5814 | 0.042 | -0.0271 | No | ||
55 | XCL1 | 3800504 | 5859 | 0.041 | -0.0291 | No | ||
56 | RNASEL | 2340133 | 5914 | 0.039 | -0.0317 | No | ||
57 | BDNF | 2940128 3520368 | 5956 | 0.038 | -0.0336 | No | ||
58 | CMAS | 2190129 | 6421 | 0.027 | -0.0585 | No | ||
59 | CACNA1E | 840253 | 7522 | 0.006 | -0.1181 | No | ||
60 | NCAM1 | 3140026 | 7611 | 0.005 | -0.1228 | No | ||
61 | AKT3 | 1580270 3290278 | 7974 | -0.001 | -0.1424 | No | ||
62 | GPA33 | 2650044 | 8073 | -0.003 | -0.1477 | No | ||
63 | TAF5 | 3450288 5890193 6860435 | 8422 | -0.008 | -0.1664 | No | ||
64 | MMP7 | 1780497 | 8492 | -0.010 | -0.1701 | No | ||
65 | GAB2 | 1410280 2340520 4280040 | 8529 | -0.010 | -0.1720 | No | ||
66 | EHF | 4560088 | 8646 | -0.012 | -0.1781 | No | ||
67 | ANKRD1 | 4850685 | 8882 | -0.016 | -0.1907 | No | ||
68 | NCF2 | 540129 2370441 2650133 | 8928 | -0.017 | -0.1930 | No | ||
69 | CPNE8 | 7040039 | 9465 | -0.026 | -0.2219 | No | ||
70 | XPNPEP1 | 2640750 3850315 6200242 | 9687 | -0.030 | -0.2336 | No | ||
71 | IPO7 | 2190746 | 10270 | -0.041 | -0.2648 | No | ||
72 | FUCA1 | 610075 | 10520 | -0.047 | -0.2779 | No | ||
73 | PDGFD | 60438 | 10524 | -0.047 | -0.2776 | No | ||
74 | PAX6 | 1190025 | 10723 | -0.052 | -0.2879 | No | ||
75 | FGF23 | 510746 | 10780 | -0.053 | -0.2905 | No | ||
76 | KAZALD1 | 380603 | 11109 | -0.062 | -0.3078 | No | ||
77 | ADAMTS4 | 430435 | 11306 | -0.067 | -0.3178 | No | ||
78 | IL18 | 6180039 | 11388 | -0.069 | -0.3216 | No | ||
79 | PGM2L1 | 2350035 | 11431 | -0.071 | -0.3233 | No | ||
80 | VPS11 | 1090048 6040372 | 11435 | -0.071 | -0.3229 | No | ||
81 | LALBA | 6940685 | 11470 | -0.072 | -0.3241 | No | ||
82 | PBXIP1 | 70131 | 11536 | -0.074 | -0.3270 | No | ||
83 | RUNX3 | 3800546 | 12636 | -0.121 | -0.3856 | No | ||
84 | MARK1 | 450484 | 12657 | -0.121 | -0.3856 | No | ||
85 | IVL | 4560500 | 12777 | -0.128 | -0.3910 | No | ||
86 | ST7L | 840735 2360576 | 12897 | -0.135 | -0.3963 | No | ||
87 | HHEX | 2340575 | 12925 | -0.138 | -0.3966 | No | ||
88 | PRDX6 | 4920397 6380601 | 13000 | -0.142 | -0.3994 | No | ||
89 | EPHA2 | 5890056 | 13204 | -0.156 | -0.4091 | No | ||
90 | CUGBP1 | 450292 510022 7050176 7050215 | 13322 | -0.166 | -0.4141 | No | ||
91 | DMBT1 | 7050270 | 13468 | -0.178 | -0.4204 | No | ||
92 | RPS3 | 1570017 2370170 | 13594 | -0.190 | -0.4256 | No | ||
93 | SLC30A7 | 2230463 | 13897 | -0.220 | -0.4401 | No | ||
94 | PLCB3 | 4670402 | 13955 | -0.227 | -0.4413 | No | ||
95 | SELP | 6040193 | 14063 | -0.237 | -0.4451 | No | ||
96 | NRGN | 4280433 | 14115 | -0.244 | -0.4458 | No | ||
97 | CD3E | 3800056 | 14211 | -0.258 | -0.4488 | No | ||
98 | GPR120 | 2350398 | 14259 | -0.265 | -0.4492 | No | ||
99 | CTSS | 1740056 | 14794 | -0.349 | -0.4752 | No | ||
100 | SORL1 | 630204 | 14932 | -0.377 | -0.4794 | No | ||
101 | ELAVL4 | 50735 3360086 5220167 | 14942 | -0.381 | -0.4767 | No | ||
102 | SYTL1 | 510487 | 14974 | -0.386 | -0.4751 | No | ||
103 | MMRN2 | 1740047 | 15083 | -0.410 | -0.4776 | No | ||
104 | CENTD2 | 60408 2510156 6100494 | 15112 | -0.415 | -0.4756 | No | ||
105 | WASF2 | 4850592 | 15120 | -0.418 | -0.4725 | No | ||
106 | BCL2L14 | 2940279 | 15363 | -0.479 | -0.4816 | Yes | ||
107 | SLC26A9 | 3440722 5340088 7510093 | 15372 | -0.481 | -0.4780 | Yes | ||
108 | LTBR | 2450341 | 15403 | -0.491 | -0.4755 | Yes | ||
109 | ETV3 | 5360487 | 15415 | -0.493 | -0.4719 | Yes | ||
110 | NUMA1 | 6520576 | 15578 | -0.548 | -0.4761 | Yes | ||
111 | ZRANB1 | 510373 4540278 | 15727 | -0.603 | -0.4791 | Yes | ||
112 | ITPKB | 2900195 7100039 | 15850 | -0.642 | -0.4803 | Yes | ||
113 | CYR61 | 1240408 5290026 4120452 6550008 | 15866 | -0.650 | -0.4756 | Yes | ||
114 | SIPA1 | 5220687 | 15944 | -0.687 | -0.4741 | Yes | ||
115 | CDKN2C | 5050750 5130148 | 15989 | -0.707 | -0.4705 | Yes | ||
116 | LRFN4 | 5670368 | 16019 | -0.723 | -0.4660 | Yes | ||
117 | EPC1 | 1570050 5290095 6900193 | 16057 | -0.741 | -0.4618 | Yes | ||
118 | SPI1 | 1410397 | 16074 | -0.748 | -0.4564 | Yes | ||
119 | KCNQ1 | 1580050 6860441 | 16104 | -0.761 | -0.4516 | Yes | ||
120 | DPP3 | 2680725 3780670 | 16191 | -0.793 | -0.4496 | Yes | ||
121 | PIK4CB | 510450 1780452 | 16250 | -0.825 | -0.4458 | Yes | ||
122 | VCAM1 | 2900450 | 16311 | -0.852 | -0.4419 | Yes | ||
123 | LAG3 | 6860112 | 16441 | -0.911 | -0.4413 | Yes | ||
124 | MFN2 | 2260195 6100164 | 16642 | -1.000 | -0.4437 | Yes | ||
125 | IL18BP | 3450128 | 16647 | -1.000 | -0.4356 | Yes | ||
126 | ADRBK1 | 1340333 | 16650 | -1.002 | -0.4273 | Yes | ||
127 | BLNK | 70288 6590092 | 16674 | -1.009 | -0.4200 | Yes | ||
128 | LCK | 3360142 | 16840 | -1.087 | -0.4199 | Yes | ||
129 | FCGR3A | 3840184 | 16851 | -1.094 | -0.4112 | Yes | ||
130 | CAP1 | 2650278 | 16901 | -1.136 | -0.4044 | Yes | ||
131 | CD53 | 5550162 | 16976 | -1.178 | -0.3985 | Yes | ||
132 | TNNI2 | 5910739 | 17006 | -1.201 | -0.3900 | Yes | ||
133 | ARHGDIB | 4730433 | 17043 | -1.226 | -0.3817 | Yes | ||
134 | GPD1 | 2480095 | 17072 | -1.243 | -0.3728 | Yes | ||
135 | ESRRA | 6550242 | 17094 | -1.257 | -0.3634 | Yes | ||
136 | SLC2A3 | 1990377 | 17099 | -1.258 | -0.3530 | Yes | ||
137 | RPS6KA4 | 2190524 | 17125 | -1.271 | -0.3437 | Yes | ||
138 | TCIRG1 | 4590524 5910079 6900619 | 17161 | -1.302 | -0.3347 | Yes | ||
139 | DGKZ | 3460041 6400129 | 17415 | -1.471 | -0.3361 | Yes | ||
140 | MAP4K2 | 4200037 | 17435 | -1.482 | -0.3247 | Yes | ||
141 | SSBP3 | 870717 1050377 7040551 | 17476 | -1.506 | -0.3142 | Yes | ||
142 | SRRM1 | 6110025 | 17668 | -1.674 | -0.3105 | Yes | ||
143 | PRF1 | 6660309 | 17671 | -1.676 | -0.2966 | Yes | ||
144 | POU2AF1 | 5690242 | 17754 | -1.745 | -0.2864 | Yes | ||
145 | NDUFS2 | 4850020 6200402 | 17779 | -1.771 | -0.2728 | Yes | ||
146 | LPXN | 2360142 | 17842 | -1.840 | -0.2607 | Yes | ||
147 | PTPN6 | 4230128 | 17901 | -1.895 | -0.2480 | Yes | ||
148 | ZNF289 | 3610390 3870711 3940138 5340373 | 17905 | -1.900 | -0.2322 | Yes | ||
149 | SELL | 1190500 | 17943 | -1.940 | -0.2179 | Yes | ||
150 | CTSW | 360368 | 18151 | -2.179 | -0.2109 | Yes | ||
151 | IL2RA | 6620450 | 18426 | -2.744 | -0.2027 | Yes | ||
152 | TYSND1 | 2940273 | 18434 | -2.760 | -0.1799 | Yes | ||
153 | SLAMF9 | 3710300 | 18458 | -2.839 | -0.1574 | Yes | ||
154 | CD5 | 6590338 | 18474 | -2.900 | -0.1339 | Yes | ||
155 | ELOVL1 | 2450019 4760138 5340685 | 18493 | -2.949 | -0.1101 | Yes | ||
156 | RHOG | 6760575 | 18532 | -3.188 | -0.0854 | Yes | ||
157 | POLD4 | 2320082 | 18561 | -3.377 | -0.0586 | Yes | ||
158 | UNC93B1 | 430152 | 18575 | -3.487 | -0.0301 | Yes | ||
159 | MAPKAPK2 | 2850500 | 18590 | -3.846 | 0.0014 | Yes |