Dataset | Set_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls #wtNotch_versus_truncNotch.phenotype_truncNotch_versus_wtNotch.cls #wtNotch_versus_truncNotch_repos |
Phenotype | phenotype_truncNotch_versus_wtNotch.cls#wtNotch_versus_truncNotch_repos |
Upregulated in class | truncNotch |
GeneSet | V$OCT1_B |
Enrichment Score (ES) | -0.4087539 |
Normalized Enrichment Score (NES) | -1.1969742 |
Nominal p-value | 0.093294464 |
FDR q-value | 1.0 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | NFYB | 1850053 | 138 | 2.739 | 0.0235 | No | ||
2 | H3F3B | 1410300 | 312 | 2.281 | 0.0399 | No | ||
3 | TSGA14 | 6660465 | 629 | 1.829 | 0.0434 | No | ||
4 | SH3BGRL | 2060110 | 1039 | 1.394 | 0.0370 | No | ||
5 | MBIP | 2640524 5570441 | 1122 | 1.315 | 0.0474 | No | ||
6 | IFIT2 | 4810735 | 1346 | 1.121 | 0.0480 | No | ||
7 | BIN3 | 380551 | 1366 | 1.101 | 0.0594 | No | ||
8 | PTEN | 3390064 | 1409 | 1.066 | 0.0691 | No | ||
9 | OTX2 | 1190471 | 1690 | 0.918 | 0.0643 | No | ||
10 | PPARGC1B | 3290114 | 1765 | 0.866 | 0.0701 | No | ||
11 | NOTCH1 | 3390114 | 1829 | 0.827 | 0.0760 | No | ||
12 | STAT4 | 1660373 3130019 | 1891 | 0.792 | 0.0817 | No | ||
13 | LPL | 1450735 2970706 | 1943 | 0.762 | 0.0875 | No | ||
14 | SCOC | 610048 2230053 | 1945 | 0.761 | 0.0961 | No | ||
15 | CSNK1E | 2850347 5050093 6110301 | 2070 | 0.684 | 0.0971 | No | ||
16 | WNT6 | 4570364 | 2225 | 0.610 | 0.0956 | No | ||
17 | TCF12 | 3610324 7000156 | 2233 | 0.608 | 0.1021 | No | ||
18 | FOXP1 | 6510433 | 2240 | 0.605 | 0.1086 | No | ||
19 | ATF7IP | 2690176 6770021 | 2406 | 0.541 | 0.1058 | No | ||
20 | FES | 3120129 5550600 | 2485 | 0.511 | 0.1074 | No | ||
21 | ZHX2 | 2900452 | 2635 | 0.461 | 0.1045 | No | ||
22 | PDE4D | 2470528 6660014 | 2699 | 0.441 | 0.1060 | No | ||
23 | LDB2 | 5670441 6110170 | 2798 | 0.409 | 0.1053 | No | ||
24 | GUCA1A | 6020338 | 2888 | 0.377 | 0.1048 | No | ||
25 | THRA | 6770341 110164 1990600 | 2995 | 0.343 | 0.1029 | No | ||
26 | NEDD4 | 460736 1190280 | 3009 | 0.339 | 0.1060 | No | ||
27 | CDK2 | 130484 2260301 4010088 5050110 | 3216 | 0.284 | 0.0981 | No | ||
28 | REL | 360707 | 3244 | 0.279 | 0.0998 | No | ||
29 | CRYZL1 | 730022 2320044 | 3293 | 0.268 | 0.1002 | No | ||
30 | MRAS | 2030524 | 3404 | 0.246 | 0.0970 | No | ||
31 | GFI1B | 4570131 | 3607 | 0.204 | 0.0883 | No | ||
32 | RGL1 | 1500097 6900450 | 3708 | 0.188 | 0.0850 | No | ||
33 | OLIG3 | 1050603 | 3822 | 0.171 | 0.0808 | No | ||
34 | HIST2H2AC | 2030600 | 3924 | 0.156 | 0.0771 | No | ||
35 | ASCL3 | 4570484 | 3989 | 0.149 | 0.0753 | No | ||
36 | PRRX1 | 4120193 4480390 | 3993 | 0.149 | 0.0769 | No | ||
37 | MAP2K6 | 1230056 2940204 | 4023 | 0.145 | 0.0769 | No | ||
38 | NR6A1 | 4010347 | 4212 | 0.126 | 0.0681 | No | ||
39 | MID1 | 4070114 4760458 | 4239 | 0.124 | 0.0681 | No | ||
40 | GPRC5B | 2760114 | 4286 | 0.120 | 0.0670 | No | ||
41 | KCTD6 | 4070435 | 4337 | 0.115 | 0.0656 | No | ||
42 | FSTL5 | 770280 | 4447 | 0.106 | 0.0609 | No | ||
43 | NRXN1 | 460408 5340270 6370066 | 4506 | 0.101 | 0.0589 | No | ||
44 | SREBF2 | 3390692 | 4567 | 0.098 | 0.0567 | No | ||
45 | CNNM4 | 1740347 | 4735 | 0.086 | 0.0486 | No | ||
46 | E2F3 | 50162 460180 | 4748 | 0.086 | 0.0490 | No | ||
47 | NDNL2 | 6550458 | 4780 | 0.084 | 0.0482 | No | ||
48 | RAB26 | 5910025 | 4827 | 0.082 | 0.0467 | No | ||
49 | SPRR2B | 60037 | 4928 | 0.076 | 0.0421 | No | ||
50 | PIM2 | 840136 5720692 7100577 | 4931 | 0.076 | 0.0428 | No | ||
51 | RRM2B | 1690025 1690465 4010400 | 4949 | 0.076 | 0.0428 | No | ||
52 | MGAT5B | 380131 2570364 | 5032 | 0.071 | 0.0391 | No | ||
53 | KCNN3 | 6520600 6420138 | 5078 | 0.069 | 0.0375 | No | ||
54 | FGF14 | 2630390 3520075 6770048 | 5163 | 0.065 | 0.0337 | No | ||
55 | EGR2 | 3800403 | 5178 | 0.065 | 0.0336 | No | ||
56 | ARPC5 | 1740411 3450300 | 5348 | 0.058 | 0.0251 | No | ||
57 | TSC1 | 1850672 | 5592 | 0.049 | 0.0125 | No | ||
58 | LYN | 6040600 | 5608 | 0.048 | 0.0122 | No | ||
59 | HOXB6 | 4210739 | 5675 | 0.046 | 0.0092 | No | ||
60 | SFRP2 | 4850097 | 5717 | 0.045 | 0.0074 | No | ||
61 | SLC24A1 | 1240463 | 5832 | 0.042 | 0.0017 | No | ||
62 | TCF2 | 870338 5050632 | 5933 | 0.039 | -0.0033 | No | ||
63 | BDNF | 2940128 3520368 | 5956 | 0.038 | -0.0040 | No | ||
64 | SILV | 2350673 | 5980 | 0.037 | -0.0048 | No | ||
65 | NEUROG1 | 380341 | 6051 | 0.035 | -0.0082 | No | ||
66 | GPC4 | 5910408 | 6054 | 0.035 | -0.0080 | No | ||
67 | SATB2 | 2470181 | 6059 | 0.035 | -0.0078 | No | ||
68 | IRX4 | 1980102 | 6094 | 0.034 | -0.0092 | No | ||
69 | PRKG1 | 4120671 | 6179 | 0.032 | -0.0134 | No | ||
70 | LIPG | 1770040 | 6295 | 0.030 | -0.0193 | No | ||
71 | CD86 | 3390471 6200280 | 6400 | 0.027 | -0.0247 | No | ||
72 | COL25A1 | 1580072 4280537 4480168 5290441 7040563 | 6552 | 0.024 | -0.0326 | No | ||
73 | MITF | 380056 | 6574 | 0.024 | -0.0335 | No | ||
74 | FGF12 | 1740446 2360037 | 6943 | 0.016 | -0.0532 | No | ||
75 | SKIL | 1090364 | 7196 | 0.012 | -0.0668 | No | ||
76 | GNB3 | 1230167 | 7312 | 0.009 | -0.0729 | No | ||
77 | PCYT1B | 1780402 | 7342 | 0.009 | -0.0744 | No | ||
78 | TLL2 | 6220040 | 7661 | 0.004 | -0.0916 | No | ||
79 | PIPOX | 70750 | 7806 | 0.002 | -0.0994 | No | ||
80 | NR2C2 | 6100097 | 8223 | -0.005 | -0.1219 | No | ||
81 | ALDH1A1 | 6520706 | 8288 | -0.006 | -0.1253 | No | ||
82 | GAB2 | 1410280 2340520 4280040 | 8529 | -0.010 | -0.1382 | No | ||
83 | EHF | 4560088 | 8646 | -0.012 | -0.1444 | No | ||
84 | PCDH20 | 4200576 | 8703 | -0.013 | -0.1473 | No | ||
85 | LRRN1 | 3290154 | 8817 | -0.015 | -0.1532 | No | ||
86 | DPYSL3 | 1580594 | 8861 | -0.016 | -0.1554 | No | ||
87 | EPHB3 | 6650341 | 9021 | -0.019 | -0.1638 | No | ||
88 | ITSN1 | 2640577 | 9091 | -0.020 | -0.1673 | No | ||
89 | HOXA13 | 3120647 | 9172 | -0.021 | -0.1714 | No | ||
90 | GPR4 | 2060358 | 9266 | -0.023 | -0.1762 | No | ||
91 | SLC19A3 | 2650601 | 9320 | -0.024 | -0.1788 | No | ||
92 | HIST1H2AH | 3710333 | 9338 | -0.024 | -0.1795 | No | ||
93 | NFIA | 2760129 5860278 | 9571 | -0.028 | -0.1917 | No | ||
94 | UPK3A | 1410717 | 9586 | -0.028 | -0.1922 | No | ||
95 | ALK | 730008 | 9602 | -0.028 | -0.1927 | No | ||
96 | RGS13 | 3780722 | 9706 | -0.030 | -0.1979 | No | ||
97 | FBXO24 | 1230132 4610121 | 9861 | -0.033 | -0.2059 | No | ||
98 | LHX6 | 2360731 3360397 | 9966 | -0.036 | -0.2111 | No | ||
99 | HDAC9 | 1990010 2260133 | 10024 | -0.037 | -0.2138 | No | ||
100 | GPM6A | 1660044 2750152 | 10198 | -0.040 | -0.2228 | No | ||
101 | NRXN3 | 1400546 3360471 | 10243 | -0.041 | -0.2247 | No | ||
102 | CRISP1 | 50181 | 10392 | -0.044 | -0.2322 | No | ||
103 | TMOD2 | 5130180 | 10480 | -0.046 | -0.2364 | No | ||
104 | PAX6 | 1190025 | 10723 | -0.052 | -0.2490 | No | ||
105 | PRDM1 | 3170347 3520301 | 10848 | -0.055 | -0.2551 | No | ||
106 | HOXC5 | 1580017 | 10899 | -0.056 | -0.2571 | No | ||
107 | VSNL1 | 3120017 | 10973 | -0.058 | -0.2604 | No | ||
108 | ADORA1 | 6370520 | 11058 | -0.060 | -0.2643 | No | ||
109 | TCEAL1 | 870577 | 11124 | -0.062 | -0.2672 | No | ||
110 | NEUROD6 | 4670731 | 11134 | -0.062 | -0.2669 | No | ||
111 | CDX4 | 6380164 | 11520 | -0.073 | -0.2870 | No | ||
112 | SYNPR | 2810400 | 11530 | -0.074 | -0.2867 | No | ||
113 | CLCA3 | 6510167 | 11565 | -0.075 | -0.2877 | No | ||
114 | BTK | 3130044 | 11642 | -0.077 | -0.2909 | No | ||
115 | ETV1 | 70735 2940603 5080463 | 11678 | -0.079 | -0.2919 | No | ||
116 | DNAH5 | 7040315 | 11782 | -0.082 | -0.2966 | No | ||
117 | DLGAP4 | 4570672 5690161 | 11817 | -0.083 | -0.2975 | No | ||
118 | SLC1A2 | 2230520 | 11915 | -0.087 | -0.3018 | No | ||
119 | STAG1 | 1190300 1400722 4590100 | 12009 | -0.091 | -0.3058 | No | ||
120 | SP6 | 60484 510452 2690333 | 12130 | -0.096 | -0.3112 | No | ||
121 | NRL | 4210110 | 12313 | -0.105 | -0.3199 | No | ||
122 | DMD | 1740041 3990332 | 12380 | -0.107 | -0.3223 | No | ||
123 | POU2F3 | 2030601 | 12520 | -0.114 | -0.3285 | No | ||
124 | HIST1H2AC | 3130292 | 12522 | -0.114 | -0.3273 | No | ||
125 | KLF12 | 1660095 4810288 5340546 6520286 | 12544 | -0.115 | -0.3271 | No | ||
126 | NXPH1 | 3870546 | 12561 | -0.116 | -0.3267 | No | ||
127 | SLC6A15 | 5290176 6040017 | 12779 | -0.128 | -0.3370 | No | ||
128 | CPD | 5360403 5860685 | 12814 | -0.130 | -0.3374 | No | ||
129 | COL23A1 | 2030358 | 12919 | -0.137 | -0.3415 | No | ||
130 | CDH13 | 5130368 5340114 | 13102 | -0.149 | -0.3496 | No | ||
131 | PFKFB1 | 2370128 | 13201 | -0.156 | -0.3532 | No | ||
132 | SOX2 | 630487 2230491 | 13234 | -0.159 | -0.3531 | No | ||
133 | VPREB3 | 3780131 | 13409 | -0.173 | -0.3606 | No | ||
134 | CSF3 | 2230193 6660707 | 13498 | -0.181 | -0.3633 | No | ||
135 | LRCH4 | 5220279 6510026 | 13501 | -0.181 | -0.3614 | No | ||
136 | SLITRK6 | 7320739 | 13830 | -0.213 | -0.3768 | No | ||
137 | EAF2 | 4280711 5080324 | 13889 | -0.218 | -0.3775 | No | ||
138 | BCDO2 | 4560279 | 13901 | -0.220 | -0.3756 | No | ||
139 | KIF13A | 5390750 | 13940 | -0.224 | -0.3751 | No | ||
140 | SRF | 70139 2320039 | 14038 | -0.235 | -0.3777 | No | ||
141 | LRRTM4 | 5910100 | 14112 | -0.243 | -0.3789 | No | ||
142 | HOXA10 | 6110397 7100458 | 14167 | -0.252 | -0.3790 | No | ||
143 | PTHLH | 5290739 | 14223 | -0.260 | -0.3790 | No | ||
144 | TRPM1 | 50746 2060301 5130100 5720129 | 14280 | -0.267 | -0.3791 | No | ||
145 | CSMD3 | 1660427 1940687 | 14391 | -0.280 | -0.3819 | No | ||
146 | HPCAL4 | 2600484 | 14438 | -0.289 | -0.3811 | No | ||
147 | TBR1 | 5130053 | 14489 | -0.297 | -0.3805 | No | ||
148 | NR1D1 | 2360471 770746 6590204 | 14570 | -0.313 | -0.3813 | No | ||
149 | NRAS | 6900577 | 14579 | -0.314 | -0.3781 | No | ||
150 | DUSP6 | 5910286 7100070 | 14628 | -0.323 | -0.3771 | No | ||
151 | ADORA2A | 1990687 | 14806 | -0.351 | -0.3827 | No | ||
152 | RHOBTB2 | 1570129 2320253 3520253 | 14845 | -0.358 | -0.3807 | No | ||
153 | SLC25A12 | 7400731 | 14940 | -0.380 | -0.3815 | No | ||
154 | POLM | 2630440 | 15317 | -0.464 | -0.3967 | No | ||
155 | POU3F4 | 870274 | 15540 | -0.535 | -0.4027 | Yes | ||
156 | CDX2 | 3850349 | 15624 | -0.567 | -0.4008 | Yes | ||
157 | KCTD12 | 7050091 | 15629 | -0.569 | -0.3946 | Yes | ||
158 | BCL2 | 730132 1570736 2470138 3800044 4810037 5690068 5860504 6650164 | 15654 | -0.579 | -0.3893 | Yes | ||
159 | ITPR3 | 4010632 | 15789 | -0.624 | -0.3895 | Yes | ||
160 | CYR61 | 1240408 5290026 4120452 6550008 | 15866 | -0.650 | -0.3863 | Yes | ||
161 | AXUD1 | 1230053 | 15881 | -0.659 | -0.3796 | Yes | ||
162 | RHOB | 1500309 | 15922 | -0.678 | -0.3741 | Yes | ||
163 | TWIST1 | 5130619 | 16407 | -0.898 | -0.3902 | Yes | ||
164 | TBXAS1 | 5050053 6900286 | 16521 | -0.949 | -0.3856 | Yes | ||
165 | FZD2 | 6480154 | 16540 | -0.962 | -0.3757 | Yes | ||
166 | HIST1H2BC | 2570156 6520315 | 16643 | -1.000 | -0.3700 | Yes | ||
167 | BLNK | 70288 6590092 | 16674 | -1.009 | -0.3602 | Yes | ||
168 | THRAP5 | 2030403 | 16681 | -1.011 | -0.3491 | Yes | ||
169 | SH3GL3 | 3800112 | 16835 | -1.084 | -0.3451 | Yes | ||
170 | RRAS | 4150609 | 16850 | -1.094 | -0.3335 | Yes | ||
171 | SESN3 | 110687 | 16981 | -1.181 | -0.3272 | Yes | ||
172 | ESRRA | 6550242 | 17094 | -1.257 | -0.3191 | Yes | ||
173 | SCML4 | 2850088 | 17325 | -1.407 | -0.3157 | Yes | ||
174 | SERTAD4 | 130593 | 17424 | -1.476 | -0.3043 | Yes | ||
175 | ACBD4 | 6980079 | 17625 | -1.628 | -0.2968 | Yes | ||
176 | HIST1H2BB | 1340035 | 17636 | -1.633 | -0.2788 | Yes | ||
177 | ARHGAP4 | 1940022 | 17729 | -1.724 | -0.2643 | Yes | ||
178 | UBE2S | 1850110 | 17741 | -1.734 | -0.2453 | Yes | ||
179 | HIST1H2BM | 3170168 | 18031 | -2.033 | -0.2380 | Yes | ||
180 | BAT2 | 6650435 | 18147 | -2.170 | -0.2197 | Yes | ||
181 | PIK3CD | 3060546 | 18276 | -2.382 | -0.1998 | Yes | ||
182 | HIST1H2BK | 6130433 | 18345 | -2.499 | -0.1752 | Yes | ||
183 | HIST1H2AB | 2680465 | 18444 | -2.796 | -0.1489 | Yes | ||
184 | CD79B | 1450066 3390358 | 18519 | -3.091 | -0.1180 | Yes | ||
185 | HIST1H3B | 4780092 | 18572 | -3.453 | -0.0818 | Yes | ||
186 | HIST2H2BE | 3360184 | 18573 | -3.486 | -0.0424 | Yes | ||
187 | HIST1H3C | 730204 | 18593 | -3.948 | 0.0012 | Yes |