Dataset | Set_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls #wtNotch_versus_truncNotch.phenotype_truncNotch_versus_wtNotch.cls #wtNotch_versus_truncNotch_repos |
Phenotype | phenotype_truncNotch_versus_wtNotch.cls#wtNotch_versus_truncNotch_repos |
Upregulated in class | wtNotch |
GeneSet | TAGCTTT,MIR-9 |
Enrichment Score (ES) | 0.5711627 |
Normalized Enrichment Score (NES) | 1.8041508 |
Nominal p-value | 0.0 |
FDR q-value | 0.0054827486 |
FWER p-Value | 0.022 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | SKP1A | 2450102 | 80 | 2.990 | 0.0247 | Yes | ||
2 | NDEL1 | 2370465 | 94 | 2.900 | 0.0521 | Yes | ||
3 | KPNB1 | 1690138 | 110 | 2.828 | 0.0788 | Yes | ||
4 | MTMR12 | 7000181 | 131 | 2.755 | 0.1045 | Yes | ||
5 | APRIN | 2810050 | 224 | 2.494 | 0.1237 | Yes | ||
6 | PSMD7 | 2030619 6220594 | 293 | 2.337 | 0.1427 | Yes | ||
7 | RAB14 | 6860139 | 320 | 2.272 | 0.1633 | Yes | ||
8 | STK4 | 2640152 | 427 | 2.091 | 0.1779 | Yes | ||
9 | VAMP4 | 4150102 | 448 | 2.064 | 0.1968 | Yes | ||
10 | ETF1 | 6770075 | 480 | 2.016 | 0.2147 | Yes | ||
11 | MAP3K7 | 6040068 | 534 | 1.929 | 0.2306 | Yes | ||
12 | SFMBT1 | 2360450 2370070 | 537 | 1.923 | 0.2492 | Yes | ||
13 | UBE2D3 | 3190452 | 542 | 1.915 | 0.2675 | Yes | ||
14 | ANKRD10 | 1240025 | 548 | 1.906 | 0.2858 | Yes | ||
15 | RAP2C | 1690132 | 588 | 1.868 | 0.3018 | Yes | ||
16 | KRAS | 2060170 | 621 | 1.838 | 0.3179 | Yes | ||
17 | TSGA14 | 6660465 | 629 | 1.829 | 0.3353 | Yes | ||
18 | SENP1 | 6100537 | 656 | 1.792 | 0.3513 | Yes | ||
19 | BCL11B | 2680673 | 746 | 1.704 | 0.3630 | Yes | ||
20 | ELOVL6 | 5340746 | 816 | 1.633 | 0.3751 | Yes | ||
21 | MECP2 | 1940450 | 835 | 1.615 | 0.3898 | Yes | ||
22 | ZHX1 | 2100110 2120286 | 850 | 1.596 | 0.4045 | Yes | ||
23 | DDX3X | 2190020 | 949 | 1.484 | 0.4136 | Yes | ||
24 | SAR1B | 2510273 | 991 | 1.442 | 0.4254 | Yes | ||
25 | GSPT1 | 5420050 | 1023 | 1.408 | 0.4374 | Yes | ||
26 | FYCO1 | 3990112 | 1082 | 1.351 | 0.4474 | Yes | ||
27 | EIF4ENIF1 | 2060341 | 1130 | 1.305 | 0.4575 | Yes | ||
28 | SOX4 | 2260091 | 1140 | 1.291 | 0.4696 | Yes | ||
29 | MIB1 | 3800537 | 1217 | 1.228 | 0.4774 | Yes | ||
30 | PHF2 | 4060300 | 1263 | 1.188 | 0.4865 | Yes | ||
31 | KCTD9 | 780577 | 1275 | 1.180 | 0.4973 | Yes | ||
32 | ARNTL | 3170463 | 1335 | 1.129 | 0.5051 | Yes | ||
33 | ACTL6A | 5220543 6290541 2450093 4590332 5270722 | 1579 | 0.982 | 0.5014 | Yes | ||
34 | PDK1 | 5290427 | 1632 | 0.956 | 0.5079 | Yes | ||
35 | TRIM33 | 580619 2230280 3990433 6200747 | 1746 | 0.879 | 0.5103 | Yes | ||
36 | KRIT1 | 2640500 4230435 4730184 | 1793 | 0.851 | 0.5161 | Yes | ||
37 | YWHAZ | 1230717 | 1828 | 0.828 | 0.5223 | Yes | ||
38 | PCAF | 2230161 2570369 6550451 | 1851 | 0.812 | 0.5290 | Yes | ||
39 | YAF2 | 940053 | 1855 | 0.810 | 0.5367 | Yes | ||
40 | ITGB1 | 5080156 6270528 | 1877 | 0.801 | 0.5433 | Yes | ||
41 | CYGB | 870347 | 2097 | 0.672 | 0.5380 | Yes | ||
42 | FBXO33 | 1510504 | 2117 | 0.664 | 0.5434 | Yes | ||
43 | TNFRSF19L | 1170168 1190358 5670270 | 2140 | 0.650 | 0.5485 | Yes | ||
44 | ERBB2IP | 580253 1090672 | 2205 | 0.621 | 0.5511 | Yes | ||
45 | CUGBP2 | 6180121 6840139 | 2277 | 0.592 | 0.5530 | Yes | ||
46 | PPP3R1 | 1190041 1570487 | 2386 | 0.549 | 0.5524 | Yes | ||
47 | PHF16 | 50373 7200161 | 2426 | 0.533 | 0.5555 | Yes | ||
48 | CIT | 2370601 | 2435 | 0.528 | 0.5602 | Yes | ||
49 | STAT1 | 6510204 6590553 | 2575 | 0.480 | 0.5573 | Yes | ||
50 | STRN3 | 1450093 6200685 | 2598 | 0.471 | 0.5607 | Yes | ||
51 | NR3C1 | 630563 | 2601 | 0.470 | 0.5651 | Yes | ||
52 | PSCD3 | 730301 | 2618 | 0.466 | 0.5688 | Yes | ||
53 | TIMP3 | 1450504 1980270 | 2689 | 0.443 | 0.5693 | Yes | ||
54 | KCNN2 | 990025 3520524 | 2733 | 0.431 | 0.5712 | Yes | ||
55 | DNAJC6 | 4590438 5900070 | 2883 | 0.378 | 0.5668 | No | ||
56 | RBBP5 | 2760735 6760164 | 2901 | 0.374 | 0.5695 | No | ||
57 | CASK | 2340215 3290576 6770215 | 3138 | 0.302 | 0.5596 | No | ||
58 | STC1 | 360161 | 3361 | 0.253 | 0.5500 | No | ||
59 | NLK | 2030010 2450041 | 3455 | 0.233 | 0.5472 | No | ||
60 | NFKBIZ | 2970450 | 3627 | 0.200 | 0.5399 | No | ||
61 | LRP4 | 1740253 | 3731 | 0.184 | 0.5361 | No | ||
62 | SLITRK3 | 5910041 | 3918 | 0.157 | 0.5276 | No | ||
63 | ATP11A | 1240717 5570603 | 4048 | 0.141 | 0.5219 | No | ||
64 | QKI | 5220093 6130044 | 4072 | 0.139 | 0.5220 | No | ||
65 | NR4A3 | 2900021 5860095 5910039 | 4076 | 0.138 | 0.5232 | No | ||
66 | HIP2 | 2810095 3990369 4120301 | 4211 | 0.126 | 0.5172 | No | ||
67 | RARG | 6760136 | 4350 | 0.114 | 0.5108 | No | ||
68 | HNRPH2 | 2630040 5720671 | 4431 | 0.107 | 0.5075 | No | ||
69 | SORCS1 | 60411 5890373 | 4496 | 0.102 | 0.5050 | No | ||
70 | AKAP2 | 5550347 | 4542 | 0.099 | 0.5036 | No | ||
71 | PCTK2 | 5700673 | 4590 | 0.096 | 0.5019 | No | ||
72 | SORCS3 | 5700309 | 4624 | 0.094 | 0.5011 | No | ||
73 | LRRC4 | 3850041 | 4655 | 0.092 | 0.5003 | No | ||
74 | HMGB2 | 2640603 | 4666 | 0.091 | 0.5007 | No | ||
75 | E2F3 | 50162 460180 | 4748 | 0.086 | 0.4971 | No | ||
76 | HIPK1 | 110193 | 4934 | 0.076 | 0.4878 | No | ||
77 | FRAS1 | 5080170 5670347 | 5341 | 0.059 | 0.4664 | No | ||
78 | SLITRK2 | 2640020 | 5443 | 0.055 | 0.4614 | No | ||
79 | DVL2 | 6110162 | 5445 | 0.055 | 0.4619 | No | ||
80 | TCEA1 | 5340070 | 5449 | 0.054 | 0.4623 | No | ||
81 | NEGR1 | 1940731 5130170 | 5494 | 0.053 | 0.4604 | No | ||
82 | NR2F2 | 3170609 3310577 | 5628 | 0.048 | 0.4536 | No | ||
83 | E2F7 | 4200056 | 5677 | 0.046 | 0.4515 | No | ||
84 | GOLGA4 | 460300 | 5836 | 0.042 | 0.4433 | No | ||
85 | KCNJ3 | 50184 | 6147 | 0.033 | 0.4268 | No | ||
86 | THRB | 1780673 | 6237 | 0.031 | 0.4223 | No | ||
87 | SLC25A37 | 6520341 460471 | 6240 | 0.031 | 0.4225 | No | ||
88 | HS6ST2 | 520133 5550603 | 6314 | 0.029 | 0.4188 | No | ||
89 | INSM1 | 3450671 | 6519 | 0.025 | 0.4080 | No | ||
90 | MITF | 380056 | 6574 | 0.024 | 0.4053 | No | ||
91 | CRK | 1230162 4780128 | 6649 | 0.022 | 0.4015 | No | ||
92 | ZIC2 | 1410408 | 6667 | 0.021 | 0.4008 | No | ||
93 | GABRA1 | 130372 | 6704 | 0.021 | 0.3991 | No | ||
94 | DR1 | 5860750 | 6911 | 0.017 | 0.3881 | No | ||
95 | CNTN4 | 1780300 5570577 6370019 | 7352 | 0.009 | 0.3643 | No | ||
96 | MMP16 | 2680139 | 7379 | 0.009 | 0.3630 | No | ||
97 | PCDH18 | 430010 | 7418 | 0.008 | 0.3610 | No | ||
98 | TLL2 | 6220040 | 7661 | 0.004 | 0.3479 | No | ||
99 | NDST1 | 1500427 5340121 | 7881 | 0.000 | 0.3360 | No | ||
100 | ZFP36L1 | 2510138 4120048 | 7959 | -0.001 | 0.3319 | No | ||
101 | AKT3 | 1580270 3290278 | 7974 | -0.001 | 0.3311 | No | ||
102 | SP5 | 3840309 | 7988 | -0.002 | 0.3304 | No | ||
103 | EDG1 | 4200619 | 7994 | -0.002 | 0.3302 | No | ||
104 | SMARCA1 | 4230315 | 8137 | -0.004 | 0.3225 | No | ||
105 | TMEM47 | 1660086 | 8316 | -0.007 | 0.3129 | No | ||
106 | ZFHX4 | 6110167 | 8520 | -0.010 | 0.3020 | No | ||
107 | ARHGAP5 | 2510619 3360035 | 8655 | -0.013 | 0.2949 | No | ||
108 | CCND2 | 5340167 | 8718 | -0.014 | 0.2916 | No | ||
109 | MPP5 | 2100148 5220632 | 8832 | -0.015 | 0.2857 | No | ||
110 | DPYSL3 | 1580594 | 8861 | -0.016 | 0.2843 | No | ||
111 | DCX | 130075 5360025 7050673 | 8862 | -0.016 | 0.2844 | No | ||
112 | TEAD1 | 2470551 | 8866 | -0.016 | 0.2844 | No | ||
113 | SET | 6650286 | 9170 | -0.021 | 0.2682 | No | ||
114 | PRPF4B | 940181 2570300 | 9654 | -0.029 | 0.2423 | No | ||
115 | EPHA7 | 1190288 4010278 | 9713 | -0.030 | 0.2395 | No | ||
116 | CRISPLD1 | 5910524 | 9724 | -0.030 | 0.2392 | No | ||
117 | GABRB3 | 4150164 | 9903 | -0.034 | 0.2299 | No | ||
118 | PRKCE | 5700053 | 9955 | -0.035 | 0.2275 | No | ||
119 | GPM6A | 1660044 2750152 | 10198 | -0.040 | 0.2147 | No | ||
120 | FBXO22 | 4760010 | 10412 | -0.045 | 0.2036 | No | ||
121 | PARD6B | 4120600 | 10431 | -0.045 | 0.2031 | No | ||
122 | LRRTM1 | 1690324 | 10730 | -0.052 | 0.1874 | No | ||
123 | ENAH | 1690292 5700300 | 10747 | -0.052 | 0.1871 | No | ||
124 | NAP1L5 | 360576 | 10955 | -0.057 | 0.1764 | No | ||
125 | CPEB3 | 3940164 | 10968 | -0.058 | 0.1763 | No | ||
126 | MEF2C | 670025 780338 | 11302 | -0.067 | 0.1589 | No | ||
127 | CALD1 | 1770129 1940397 | 11403 | -0.070 | 0.1542 | No | ||
128 | OSBPL8 | 50603 | 11506 | -0.073 | 0.1494 | No | ||
129 | WAC | 5340390 5910164 | 11562 | -0.075 | 0.1471 | No | ||
130 | ZFPM2 | 460072 | 11783 | -0.082 | 0.1360 | No | ||
131 | PLCG1 | 6020369 | 11960 | -0.089 | 0.1273 | No | ||
132 | SLC16A1 | 50433 | 12004 | -0.091 | 0.1258 | No | ||
133 | SOX3 | 4570537 | 12246 | -0.101 | 0.1137 | No | ||
134 | HOXB5 | 2900538 | 12257 | -0.101 | 0.1142 | No | ||
135 | POU4F1 | 2260315 | 12389 | -0.108 | 0.1081 | No | ||
136 | PIGF | 5690050 | 12424 | -0.109 | 0.1073 | No | ||
137 | ELAVL2 | 360181 | 12761 | -0.127 | 0.0904 | No | ||
138 | SOX21 | 1050110 4670041 6660338 | 12869 | -0.134 | 0.0859 | No | ||
139 | STX16 | 70315 | 12908 | -0.136 | 0.0851 | No | ||
140 | CREB5 | 2320368 | 13030 | -0.144 | 0.0800 | No | ||
141 | TPD52 | 670463 4610541 | 13088 | -0.149 | 0.0783 | No | ||
142 | PI15 | 3840133 | 13193 | -0.155 | 0.0742 | No | ||
143 | SOX2 | 630487 2230491 | 13234 | -0.159 | 0.0736 | No | ||
144 | SOCS4 | 1170162 | 13241 | -0.160 | 0.0748 | No | ||
145 | THBD | 1500092 | 13335 | -0.167 | 0.0714 | No | ||
146 | HTR2C | 380497 | 13400 | -0.172 | 0.0696 | No | ||
147 | BACH2 | 6760131 | 13451 | -0.177 | 0.0686 | No | ||
148 | POU3F2 | 6620484 | 13503 | -0.181 | 0.0676 | No | ||
149 | HOXB13 | 4730152 | 13802 | -0.210 | 0.0534 | No | ||
150 | SLITRK6 | 7320739 | 13830 | -0.213 | 0.0541 | No | ||
151 | PHF6 | 3120632 3990041 | 14457 | -0.291 | 0.0229 | No | ||
152 | AFF3 | 3870102 | 14584 | -0.315 | 0.0192 | No | ||
153 | MAGI1 | 6510500 1990239 4670471 | 14593 | -0.316 | 0.0218 | No | ||
154 | SLC9A9 | 1940309 | 14882 | -0.366 | 0.0097 | No | ||
155 | GSPT2 | 6590674 | 14959 | -0.384 | 0.0093 | No | ||
156 | PPP1R8 | 6290292 | 15025 | -0.397 | 0.0097 | No | ||
157 | ATXN1 | 5550156 | 15042 | -0.402 | 0.0127 | No | ||
158 | LRP12 | 2370112 | 15485 | -0.517 | -0.0062 | No | ||
159 | CFL2 | 380239 6200368 | 15581 | -0.551 | -0.0060 | No | ||
160 | GPHN | 3290195 3840121 | 15607 | -0.562 | -0.0019 | No | ||
161 | CYR61 | 1240408 5290026 4120452 6550008 | 15866 | -0.650 | -0.0096 | No | ||
162 | CAMK2G | 630097 | 15963 | -0.695 | -0.0081 | No | ||
163 | NCKIPSD | 2940156 | 16009 | -0.717 | -0.0035 | No | ||
164 | CPEB2 | 4760338 | 16145 | -0.773 | -0.0034 | No | ||
165 | SERF2 | 5720010 | 16283 | -0.840 | -0.0026 | No | ||
166 | TARDBP | 870390 2350093 | 16452 | -0.917 | -0.0028 | No | ||
167 | HNRPA2B1 | 1240619 6200161 6200494 6980408 | 16949 | -1.163 | -0.0184 | No | ||
168 | PITPNM2 | 1580044 | 16986 | -1.183 | -0.0089 | No | ||
169 | ZMYND11 | 630181 2570019 4850138 5360040 | 17097 | -1.258 | -0.0027 | No | ||
170 | TPM1 | 130673 | 17733 | -1.728 | -0.0203 | No | ||
171 | DTX3 | 1690458 | 17800 | -1.796 | -0.0064 | No | ||
172 | HRB | 1660397 6110398 | 18275 | -2.382 | -0.0090 | No | ||
173 | SFRS2 | 50707 380593 | 18457 | -2.828 | 0.0086 | No |