Dataset | Set_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls #wtNotch_versus_truncNotch.phenotype_truncNotch_versus_wtNotch.cls #wtNotch_versus_truncNotch_repos |
Phenotype | phenotype_truncNotch_versus_wtNotch.cls#wtNotch_versus_truncNotch_repos |
Upregulated in class | wtNotch |
GeneSet | ATACTGT,MIR-144 |
Enrichment Score (ES) | 0.576362 |
Normalized Enrichment Score (NES) | 1.7989106 |
Nominal p-value | 0.0 |
FDR q-value | 0.0047937427 |
FWER p-Value | 0.023 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | MARCKS | 7040450 | 21 | 3.674 | 0.0454 | Yes | ||
2 | APPBP2 | 5130215 | 37 | 3.469 | 0.0884 | Yes | ||
3 | ARID1A | 2630022 1690551 4810110 | 78 | 2.995 | 0.1242 | Yes | ||
4 | SIN3A | 2190121 | 191 | 2.561 | 0.1505 | Yes | ||
5 | MAPK6 | 6760520 | 292 | 2.346 | 0.1748 | Yes | ||
6 | HAT1 | 3710082 | 301 | 2.321 | 0.2037 | Yes | ||
7 | KPNA1 | 5270324 | 304 | 2.308 | 0.2328 | Yes | ||
8 | PABPN1 | 460519 | 342 | 2.228 | 0.2590 | Yes | ||
9 | MTPN | 3940167 | 400 | 2.138 | 0.2830 | Yes | ||
10 | UBE2D3 | 3190452 | 542 | 1.915 | 0.2996 | Yes | ||
11 | ZFX | 5900400 | 704 | 1.744 | 0.3129 | Yes | ||
12 | GCNT2 | 6400162 2370609 2760309 4540465 6100280 | 708 | 1.741 | 0.3348 | Yes | ||
13 | ITSN2 | 780484 | 770 | 1.677 | 0.3527 | Yes | ||
14 | PHTF2 | 6590053 | 795 | 1.656 | 0.3724 | Yes | ||
15 | ACBD3 | 2760170 | 878 | 1.570 | 0.3878 | Yes | ||
16 | GSPT1 | 5420050 | 1023 | 1.408 | 0.3979 | Yes | ||
17 | PKNOX1 | 4210452 | 1043 | 1.390 | 0.4144 | Yes | ||
18 | CCNE2 | 3120537 | 1049 | 1.388 | 0.4317 | Yes | ||
19 | SLC23A2 | 6660722 | 1054 | 1.380 | 0.4489 | Yes | ||
20 | HNRPU | 6520736 | 1351 | 1.114 | 0.4470 | Yes | ||
21 | UBE2D2 | 4590671 6510446 | 1363 | 1.102 | 0.4604 | Yes | ||
22 | PPP1R16B | 3520300 | 1379 | 1.091 | 0.4734 | Yes | ||
23 | EIF5 | 6380750 | 1400 | 1.073 | 0.4859 | Yes | ||
24 | CD28 | 1400739 4210093 | 1578 | 0.983 | 0.4887 | Yes | ||
25 | TFRC | 4050551 | 1622 | 0.963 | 0.4986 | Yes | ||
26 | EIF4G2 | 3800575 6860184 | 1689 | 0.918 | 0.5066 | Yes | ||
27 | GATA3 | 6130068 | 1785 | 0.855 | 0.5123 | Yes | ||
28 | NGFRAP1 | 6770195 | 1831 | 0.825 | 0.5203 | Yes | ||
29 | PFKFB2 | 3940538 7100059 | 1917 | 0.777 | 0.5255 | Yes | ||
30 | PUM1 | 6130500 | 2191 | 0.627 | 0.5187 | Yes | ||
31 | FUSIP1 | 520082 5390114 | 2247 | 0.602 | 0.5233 | Yes | ||
32 | ARFGEF1 | 6760494 | 2271 | 0.593 | 0.5296 | Yes | ||
33 | CUGBP2 | 6180121 6840139 | 2277 | 0.592 | 0.5368 | Yes | ||
34 | HSF2 | 1400465 | 2359 | 0.559 | 0.5395 | Yes | ||
35 | FOXO1A | 3120670 | 2373 | 0.553 | 0.5458 | Yes | ||
36 | PPP3R1 | 1190041 1570487 | 2386 | 0.549 | 0.5521 | Yes | ||
37 | SLC7A11 | 2850138 | 2595 | 0.473 | 0.5468 | Yes | ||
38 | NR3C1 | 630563 | 2601 | 0.470 | 0.5525 | Yes | ||
39 | NARG1 | 5910563 6350095 | 2607 | 0.469 | 0.5581 | Yes | ||
40 | ALS2 | 3130546 6400070 | 2671 | 0.448 | 0.5604 | Yes | ||
41 | PDE4D | 2470528 6660014 | 2699 | 0.441 | 0.5645 | Yes | ||
42 | SUCLA2 | 730632 1170292 | 2809 | 0.406 | 0.5638 | Yes | ||
43 | CLK1 | 1780551 2100102 2340347 2480347 | 2844 | 0.390 | 0.5669 | Yes | ||
44 | RNF111 | 2970072 3140112 5130647 | 2847 | 0.389 | 0.5717 | Yes | ||
45 | FBXL3 | 5910142 | 2852 | 0.387 | 0.5764 | Yes | ||
46 | NEDD4 | 460736 1190280 | 3009 | 0.339 | 0.5722 | No | ||
47 | CRSP2 | 1940059 | 3176 | 0.292 | 0.5669 | No | ||
48 | ACSL4 | 510020 1240041 3190050 4540500 5570463 | 3332 | 0.258 | 0.5618 | No | ||
49 | ZIC4 | 1500082 | 3339 | 0.256 | 0.5647 | No | ||
50 | FNDC3A | 2690097 3290044 | 3438 | 0.236 | 0.5624 | No | ||
51 | ARRDC3 | 4610390 | 3475 | 0.230 | 0.5633 | No | ||
52 | BRPF1 | 3170139 | 3504 | 0.224 | 0.5646 | No | ||
53 | PTPN9 | 3290408 | 3517 | 0.220 | 0.5668 | No | ||
54 | RBM12 | 4570239 6040411 6660129 | 3764 | 0.179 | 0.5557 | No | ||
55 | FBXO32 | 110037 610750 | 3834 | 0.170 | 0.5541 | No | ||
56 | CCT2 | 1690113 | 4040 | 0.142 | 0.5448 | No | ||
57 | QKI | 5220093 6130044 | 4072 | 0.139 | 0.5449 | No | ||
58 | PALM2 | 4120068 7100398 | 4410 | 0.109 | 0.5280 | No | ||
59 | RHOBTB1 | 1410010 | 4491 | 0.103 | 0.5250 | No | ||
60 | SORCS3 | 5700309 | 4624 | 0.094 | 0.5190 | No | ||
61 | VKORC1L1 | 110220 1400050 | 4794 | 0.083 | 0.5109 | No | ||
62 | CAPZA1 | 3140390 | 4951 | 0.075 | 0.5034 | No | ||
63 | GDF10 | 4850082 | 5252 | 0.062 | 0.4880 | No | ||
64 | CCNK | 6980048 | 5366 | 0.057 | 0.4826 | No | ||
65 | PTP4A1 | 130692 | 5455 | 0.054 | 0.4785 | No | ||
66 | ATP2B2 | 3780397 | 5465 | 0.054 | 0.4787 | No | ||
67 | FOSB | 1940142 | 5598 | 0.049 | 0.4721 | No | ||
68 | WTAP | 4010176 | 5624 | 0.048 | 0.4714 | No | ||
69 | NR2F2 | 3170609 3310577 | 5628 | 0.048 | 0.4718 | No | ||
70 | PURA | 3870156 | 5900 | 0.040 | 0.4577 | No | ||
71 | CBX4 | 70332 | 5974 | 0.038 | 0.4542 | No | ||
72 | RARB | 430139 1410138 | 6002 | 0.037 | 0.4532 | No | ||
73 | IDH2 | 2680397 | 6044 | 0.035 | 0.4514 | No | ||
74 | LIFR | 3360068 3830102 | 6164 | 0.033 | 0.4454 | No | ||
75 | AHCY | 4230605 | 6268 | 0.030 | 0.4402 | No | ||
76 | NRP2 | 4070400 5860041 6650446 | 6307 | 0.030 | 0.4385 | No | ||
77 | SNAP91 | 3170056 5690520 | 6406 | 0.027 | 0.4335 | No | ||
78 | CXCL12 | 580546 4150750 4570068 | 6718 | 0.020 | 0.4170 | No | ||
79 | PLAG1 | 1450142 3870139 6520039 | 6905 | 0.017 | 0.4071 | No | ||
80 | FAM60A | 3940092 | 6912 | 0.017 | 0.4070 | No | ||
81 | MYT1 | 6770524 | 6942 | 0.016 | 0.4056 | No | ||
82 | PANK1 | 670091 6220605 | 7146 | 0.012 | 0.3948 | No | ||
83 | RGS16 | 780091 | 7364 | 0.009 | 0.3831 | No | ||
84 | PAX3 | 50551 | 7369 | 0.009 | 0.3830 | No | ||
85 | PCDH18 | 430010 | 7418 | 0.008 | 0.3805 | No | ||
86 | FBXW11 | 6450632 | 7458 | 0.007 | 0.3785 | No | ||
87 | SS18 | 1940440 2900072 6900129 | 7497 | 0.007 | 0.3765 | No | ||
88 | GLCCI1 | 110091 2640082 2900692 3290070 6370014 | 7530 | 0.006 | 0.3749 | No | ||
89 | HNRPF | 670138 | 7677 | 0.004 | 0.3670 | No | ||
90 | CAV2 | 5130286 5130563 | 7999 | -0.002 | 0.3497 | No | ||
91 | ELL2 | 6420091 | 8041 | -0.002 | 0.3475 | No | ||
92 | SMARCA1 | 4230315 | 8137 | -0.004 | 0.3424 | No | ||
93 | PPARA | 2060026 | 8143 | -0.004 | 0.3421 | No | ||
94 | MSX1 | 2650309 | 8255 | -0.006 | 0.3362 | No | ||
95 | RIN2 | 2450184 | 8323 | -0.007 | 0.3327 | No | ||
96 | ZCCHC2 | 460592 | 8368 | -0.008 | 0.3304 | No | ||
97 | UBE4A | 6100520 | 8544 | -0.011 | 0.3210 | No | ||
98 | SP4 | 3850176 | 8553 | -0.011 | 0.3207 | No | ||
99 | ESRRG | 4010181 | 8690 | -0.013 | 0.3135 | No | ||
100 | FMN2 | 450463 | 8894 | -0.016 | 0.3027 | No | ||
101 | MYO1E | 3140504 | 9122 | -0.020 | 0.2907 | No | ||
102 | SLITRK4 | 5910022 | 9165 | -0.021 | 0.2887 | No | ||
103 | TBX1 | 3710133 6590121 | 9268 | -0.023 | 0.2835 | No | ||
104 | RFX4 | 3710100 5340215 | 9454 | -0.026 | 0.2738 | No | ||
105 | LGR4 | 1660309 | 9639 | -0.029 | 0.2642 | No | ||
106 | WDFY3 | 3610041 4560333 4570273 | 9973 | -0.036 | 0.2466 | No | ||
107 | TTN | 2320161 4670056 6550026 | 10145 | -0.039 | 0.2378 | No | ||
108 | ST18 | 5720537 | 10237 | -0.041 | 0.2334 | No | ||
109 | MEIS1 | 1400575 | 10393 | -0.044 | 0.2256 | No | ||
110 | PNRC1 | 360025 | 10452 | -0.046 | 0.2230 | No | ||
111 | ALDH1A3 | 2100270 | 10810 | -0.054 | 0.2044 | No | ||
112 | CPEB3 | 3940164 | 10968 | -0.058 | 0.1966 | No | ||
113 | ANK2 | 6510546 | 10979 | -0.058 | 0.1968 | No | ||
114 | CDH11 | 1230133 2100180 4610110 | 11003 | -0.059 | 0.1963 | No | ||
115 | SEMA6A | 2690138 3060021 | 11083 | -0.061 | 0.1928 | No | ||
116 | FMR1 | 5050075 | 11166 | -0.063 | 0.1891 | No | ||
117 | PAFAH1B1 | 4230333 6420121 6450066 | 11397 | -0.070 | 0.1775 | No | ||
118 | SFRP1 | 6980315 | 11505 | -0.073 | 0.1727 | No | ||
119 | CBX1 | 5080408 1980239 | 11701 | -0.079 | 0.1631 | No | ||
120 | ST6GALNAC3 | 4070563 | 11953 | -0.089 | 0.1506 | No | ||
121 | STAG1 | 1190300 1400722 4590100 | 12009 | -0.091 | 0.1488 | No | ||
122 | SEMA6D | 4050324 5860138 6350307 | 12249 | -0.101 | 0.1371 | No | ||
123 | TRIB1 | 2320435 | 12339 | -0.106 | 0.1337 | No | ||
124 | DMD | 1740041 3990332 | 12380 | -0.107 | 0.1328 | No | ||
125 | DGCR2 | 780041 4010731 | 12512 | -0.114 | 0.1272 | No | ||
126 | CALCRL | 4280035 | 12703 | -0.124 | 0.1185 | No | ||
127 | SMPD3 | 520164 | 12801 | -0.130 | 0.1149 | No | ||
128 | WIF1 | 7100184 | 13016 | -0.143 | 0.1051 | No | ||
129 | ARID5B | 110403 | 13120 | -0.151 | 0.1014 | No | ||
130 | CDH2 | 520435 2450451 2760025 6650477 | 13303 | -0.164 | 0.0936 | No | ||
131 | BACH2 | 6760131 | 13451 | -0.177 | 0.0879 | No | ||
132 | PAPPA | 4230463 | 13720 | -0.202 | 0.0759 | No | ||
133 | SLC12A2 | 4610019 6040672 | 13803 | -0.210 | 0.0742 | No | ||
134 | NFE2L2 | 2810619 3390162 | 13905 | -0.221 | 0.0715 | No | ||
135 | EDAR | 6220670 | 13960 | -0.227 | 0.0714 | No | ||
136 | JPH1 | 610739 | 13987 | -0.230 | 0.0729 | No | ||
137 | PTGFRN | 4120524 | 14059 | -0.237 | 0.0721 | No | ||
138 | HOXA10 | 6110397 7100458 | 14167 | -0.252 | 0.0695 | No | ||
139 | PTHLH | 5290739 | 14223 | -0.260 | 0.0698 | No | ||
140 | ATXN1 | 5550156 | 15042 | -0.402 | 0.0306 | No | ||
141 | PDE7B | 5700056 | 15069 | -0.408 | 0.0343 | No | ||
142 | NIN | 3450576 5080048 | 15109 | -0.414 | 0.0375 | No | ||
143 | ETS1 | 5270278 6450717 6620465 | 15339 | -0.470 | 0.0310 | No | ||
144 | LHX2 | 3610463 | 15527 | -0.532 | 0.0276 | No | ||
145 | STARD8 | 1780047 | 15637 | -0.571 | 0.0289 | No | ||
146 | DLG5 | 450215 | 15777 | -0.620 | 0.0293 | No | ||
147 | CPEB2 | 4760338 | 16145 | -0.773 | 0.0192 | No | ||
148 | PIM1 | 630047 | 16318 | -0.856 | 0.0207 | No | ||
149 | SON | 3120148 5860239 7040403 | 16514 | -0.945 | 0.0221 | No | ||
150 | MYST3 | 5270500 | 16814 | -1.077 | 0.0195 | No | ||
151 | HDHD2 | 2850411 6940168 | 17083 | -1.249 | 0.0208 | No | ||
152 | ATP5G2 | 840068 | 17218 | -1.340 | 0.0305 | No | ||
153 | ARID2 | 110647 5390435 | 17432 | -1.479 | 0.0377 | No | ||
154 | AGRN | 6770152 | 18074 | -2.084 | 0.0294 | No |