Details for gene set UVB_NHEK1

Table: GSEA Results Summary

Dataset	Set_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls #wtNotch_versus_truncNotch.phenotype_truncNotch_versus_wtNotch.cls #wtNotch_versus_truncNotch_repos
Phenotype	phenotype_truncNotch_versus_wtNotch.cls#wtNotch_versus_truncNotch_repos
Upregulated in class	wtNotch
GeneSet	UVB_NHEK1_DN
Enrichment Score (ES)	0.5624498
Normalized Enrichment Score (NES)	1.773009
Nominal p-value	0.0
FDR q-value	0.041505683
FWER p-Value	0.301

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	SMAD5	5700497	4	4.407	0.0366	Yes
2	APPBP2	5130215	37	3.469	0.0639	Yes
3	ELF1	4780450	39	3.453	0.0926	Yes
4	UBE2G1	2230546 5420528 7040463	61	3.099	0.1174	Yes
5	CTCF	5340017	172	2.618	0.1333	Yes
6	PIK3C3	6590717	226	2.492	0.1513	Yes
7	ZBED4	770441	243	2.450	0.1709	Yes
8	UBL3	6450458	327	2.259	0.1852	Yes
9	POLS	5890438	424	2.095	0.1975	Yes
10	SMC5	3440164	437	2.080	0.2142	Yes
11	ZNF638	6510112	494	1.998	0.2279	Yes
12	TNFAIP8	2760551	504	1.986	0.2440	Yes
13	POLD3	6400278	553	1.899	0.2573	Yes
14	TLK1	7100605	567	1.887	0.2723	Yes
15	FEM1B	1230110	622	1.837	0.2847	Yes
16	ZBTB24	4570504	635	1.825	0.2993	Yes
17	XPA	6660133	675	1.776	0.3121	Yes
18	WDHD1	3450390	692	1.755	0.3259	Yes
19	TLK2	1170161	713	1.733	0.3393	Yes
20	DIDO1	1500601	726	1.717	0.3529	Yes
21	SPOP	450035	740	1.710	0.3665	Yes
22	CUL1	1990632	772	1.677	0.3789	Yes
23	MECP2	1940450	835	1.615	0.3890	Yes
24	CHD1	4590048	880	1.565	0.3997	Yes
25	TOP2A	360717	909	1.531	0.4109	Yes
26	PRKCD	770592	914	1.525	0.4235	Yes
27	PTK2	1780148	970	1.461	0.4327	Yes
28	KIF23	5570112	1019	1.409	0.4419	Yes
29	KLF7	50390	1029	1.403	0.4531	Yes
30	USP6NL	2940068	1031	1.400	0.4647	Yes
31	SFRS2IP	730687 1500373	1117	1.317	0.4711	Yes
32	TAF11	5720538	1128	1.306	0.4815	Yes
33	BCL7A	4560095	1148	1.282	0.4912	Yes
34	KBTBD2	2320014	1175	1.261	0.5003	Yes
35	CASP8	4850154	1285	1.166	0.5041	Yes
36	AURKA	780537	1317	1.140	0.5120	Yes
37	CREBBP	5690035 7040050	1378	1.091	0.5178	Yes
38	EIF2C2	770451	1420	1.057	0.5244	Yes
39	REV3L	1090717	1424	1.054	0.5331	Yes
40	DMTF1	5910047 1570497 2480100 6620239	1494	1.016	0.5378	Yes
41	ARID3A	6520605	1512	1.006	0.5453	Yes
42	INSIG2	3840603 5700605 6450451	1646	0.944	0.5460	Yes
43	KEAP1	1570121 2900546 3840576	1869	0.805	0.5407	Yes
44	CENPA	5080154	1872	0.803	0.5473	Yes
45	ABL1	1050593 2030050 4010114	1898	0.789	0.5525	Yes
46	BIRC2	2940435 4730020	1953	0.757	0.5559	Yes
47	KLF9	3840022	2009	0.722	0.5589	Yes
48	CNOT4	2320242 6760706	2069	0.685	0.5615	Yes
49	ZNF148	6420403	2172	0.635	0.5612	Yes
50	FOXO1A	3120670	2373	0.553	0.5550	Yes
51	PPP1R12A	4070066 4590162	2404	0.543	0.5579	Yes
52	SMC4	5910240	2448	0.524	0.5600	Yes
53	RCHY1	3800739	2482	0.512	0.5624	Yes
54	ZHX2	2900452	2635	0.461	0.5581	No
55	DYRK1A	3190181	2750	0.423	0.5554	No
56	ATF2	2260348 2480441	2797	0.409	0.5563	No
57	PCF11	1240180	2964	0.353	0.5503	No
58	ADCY9	5690168	3068	0.321	0.5474	No
59	DTX2	4210041 7000008	3104	0.312	0.5481	No
60	CTBP2	430309 3710079	3211	0.285	0.5447	No
61	NCOA3	4540195	3304	0.265	0.5419	No
62	FNDC3A	2690097 3290044	3438	0.236	0.5367	No
63	CLASP1	6860279	3529	0.218	0.5336	No
64	NPAT	3800594 4670026	3543	0.214	0.5347	No
65	SLC9A6	4570091 7100097	3555	0.212	0.5359	No
66	PPRC1	1740441	3650	0.198	0.5324	No
67	ZZZ3	780133 2320239 2640452 5080706 6550341	3664	0.194	0.5333	No
68	TLE4	1450064 1500519	3753	0.181	0.5301	No
69	WEE1	3390070	3884	0.160	0.5244	No
70	LASS6	5890576 6520138	3991	0.149	0.5198	No
71	ORC2L	1990470 6510019	4029	0.144	0.5190	No
72	CDKN1B	3800025 6450044	4044	0.142	0.5195	No
73	THRAP2	4920600	4133	0.134	0.5158	No
74	PHLPP	3440563	4359	0.114	0.5046	No
75	TBC1D8	2340253	4463	0.105	0.4998	No
76	RSBN1	7000487	4665	0.091	0.4897	No
77	PPP1R3C	2640170	4746	0.086	0.4861	No
78	E2F3	50162 460180	4748	0.086	0.4867	No
79	PIK3R4	1990132	4781	0.084	0.4857	No
80	PIP5K3	5360112	4825	0.082	0.4841	No
81	EFNB2	5340136	4906	0.077	0.4804	No
82	HMGA2	2940121 3390647 5130279 6400136	4946	0.076	0.4789	No
83	BCAR3	1660717	4988	0.073	0.4773	No
84	PRSS12	1230364 6220059	5055	0.070	0.4743	No
85	SLBP	6220601	5075	0.069	0.4738	No
86	FGFR2	4670601 5570402 6940377	5095	0.069	0.4734	No
87	GCLC	2810731	5135	0.067	0.4718	No
88	IRAK1BP1	610037	5240	0.062	0.4667	No
89	PIP5K2B	6520156 6620541	5432	0.055	0.4568	No
90	CCNB2	6510528	5570	0.050	0.4498	No
91	NR2F2	3170609 3310577	5628	0.048	0.4471	No
92	ATRX	2340039 3610132 4210373	5863	0.041	0.4347	No
93	MTIF2	2260270	5968	0.038	0.4294	No
94	SPEN	2060041	5991	0.037	0.4285	No
95	NUP153	7000452	6085	0.035	0.4238	No
96	E2F5	5860575	6252	0.031	0.4150	No
97	MYC	380541 4670170	6382	0.028	0.4083	No
98	TTC9	460463	6513	0.025	0.4014	No
99	CENPF	5050088	6665	0.022	0.3934	No
100	MYST4	1400563 2570687 3360458 6840402	6692	0.021	0.3922	No
101	PTPN3	870369	6797	0.019	0.3867	No
102	CENPC1	610273	6826	0.018	0.3853	No
103	ZCCHC11	3390731 5360039	6837	0.018	0.3849	No
104	PUM2	4200441 5910446	7013	0.015	0.3756	No
105	VEGFC	5910494	7045	0.014	0.3740	No
106	IRS1	1190204	7097	0.013	0.3713	No
107	SMAD7	430377	7413	0.008	0.3543	No
108	MTMR6	4810520	7464	0.007	0.3517	No
109	WDR37	2630519 6840347	7620	0.004	0.3433	No
110	SP3	3840338	7643	0.004	0.3421	No
111	XPO1	540707	7753	0.002	0.3363	No
112	BTBD3	1980041 2510577 3190053 4200746	8632	-0.012	0.2887	No
113	MTUS1	780348 4920609	8643	-0.012	0.2883	No
114	SLC7A1	2450193 2710241	8691	-0.013	0.2859	No
115	PLEKHC1	2650066	8839	-0.015	0.2780	No
116	SERTAD2	2810673 6840450	9012	-0.019	0.2688	No
117	POLE2	6110041	9182	-0.021	0.2598	No
118	ZCCHC14	5900288	9229	-0.022	0.2575	No
119	BDKRB2	4780706	9343	-0.024	0.2516	No
120	KIF11	5390139	9371	-0.025	0.2503	No
121	TIPARP	50397	9523	-0.027	0.2424	No
122	SKAP2	6760500	9584	-0.028	0.2394	No
123	KIF2A	3990286 6130575	9800	-0.032	0.2280	No
124	NCK1	6200575 6510050	9839	-0.033	0.2262	No
125	WDFY3	3610041 4560333 4570273	9973	-0.036	0.2193	No
126	POGZ	870348 7040286	9977	-0.036	0.2194	No
127	RRS1	4560551	10333	-0.043	0.2005	No
128	CBLB	3520465 4670348	10389	-0.044	0.1979	No
129	MEIS1	1400575	10393	-0.044	0.1981	No
130	LPP	1660541	10461	-0.046	0.1948	No
131	NRIP1	3190039	10549	-0.048	0.1905	No
132	ARHGEF7	1690441	10801	-0.054	0.1774	No
133	NPAS2	770670	10825	-0.054	0.1766	No
134	BRD8	1170463 2900075 4050397 6590332	10842	-0.055	0.1762	No
135	CPEB3	3940164	10968	-0.058	0.1699	No
136	LPHN2	4480010	11174	-0.063	0.1593	No
137	PAFAH1B1	4230333 6420121 6450066	11397	-0.070	0.1478	No
138	RNF13	2370021	11518	-0.073	0.1419	No
139	TUBGCP3	4920563	11575	-0.075	0.1395	No
140	MTM1	3060112 3170161	11707	-0.079	0.1331	No
141	GNE	6100465	11789	-0.083	0.1293	No
142	MAP3K5	6020041 6380162	11955	-0.089	0.1211	No
143	ZNF318	5890091 6130021	12435	-0.110	0.0961	No
144	CREB3L2	3390484	12612	-0.119	0.0875	No
145	RABGAP1L	3190014 6860088	12620	-0.120	0.0881	No
146	RAPGEF5	1500603 3450427 6130056	12707	-0.124	0.0845	No
147	ADORA2B	6860253	12750	-0.126	0.0833	No
148	STRN	5570706 7050333	13039	-0.145	0.0689	No
149	ARID5B	110403	13120	-0.151	0.0658	No
150	AHR	4560671	13546	-0.185	0.0443	No
151	PER2	3120204 3390593	13554	-0.186	0.0455	No
152	DOCK4	5910102	13691	-0.199	0.0398	No
153	NFE2L2	2810619 3390162	13905	-0.221	0.0300	No
154	USP1	2760541 5690438 6220673	13945	-0.225	0.0298	No
155	PLK4	430162 5720110	14001	-0.232	0.0288	No
156	SH2B3	4810451 4850128	14088	-0.240	0.0261	No
157	FYN	2100468 4760520 4850687	14227	-0.260	0.0208	No
158	MEGF9	2320097	14298	-0.269	0.0192	No
159	CDYL	4200142 4730397 6060400	14418	-0.284	0.0152	No
160	CNOT2	520546 2060397 4610543 5550113	14533	-0.305	0.0115	No
161	DDIT4	2570408	15052	-0.404	-0.0132	No
162	HDHD1A	6220328	15057	-0.405	-0.0100	No
163	SHOC2	1340064 1570546	15161	-0.426	-0.0120	No
164	TAF5L	5690152	15178	-0.430	-0.0093	No
165	AKAP9	510184 2060195 2470136 4280048	15191	-0.433	-0.0064	No
166	CEBPD	3360176	15386	-0.485	-0.0128	No
167	MKI67	3440750 4480072 7050288	15445	-0.502	-0.0118	No
168	BACH1	290195	16029	-0.727	-0.0373	No
169	PSCD1	110113 2470592	16179	-0.787	-0.0388	No
170	NFKB1	5420358	16242	-0.822	-0.0353	No
171	DOCK9	5080037	16476	-0.930	-0.0402	No
172	USP24	870672 4560100	16812	-1.076	-0.0494	No
173	MYST3	5270500	16814	-1.077	-0.0404	No
174	SSBP2	2260725 2900400 4730711	16927	-1.151	-0.0369	No
175	SART3	6060646	17024	-1.210	-0.0320	No
176	CCNE1	110064	17292	-1.384	-0.0349	No
177	NAGK	730041 3170086 5890053	18060	-2.070	-0.0592	No
178	SMAD3	6450671	18195	-2.238	-0.0478	No
179	PHC2	1430433	18388	-2.617	-0.0364	No
180	IGF2BP3	2810161 4230338	18402	-2.664	-0.0148	No
181	ADRB2	3290373	18525	-3.156	0.0049	No