Details for gene set TARTE_MATURE

Table: GSEA Results Summary

Dataset	Set_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls #wtNotch_versus_truncNotch.phenotype_truncNotch_versus_wtNotch.cls #wtNotch_versus_truncNotch_repos
Phenotype	phenotype_truncNotch_versus_wtNotch.cls#wtNotch_versus_truncNotch_repos
Upregulated in class	truncNotch
GeneSet	TARTE_MATURE_PC
Enrichment Score (ES)	-0.53189355
Normalized Enrichment Score (NES)	-1.6231768
Nominal p-value	0.0
FDR q-value	0.16104604
FWER p-Value	0.938

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	MX2	2030373	63	3.093	0.0142	No
2	SATB1	5670154	99	2.867	0.0287	No
3	CD8B	1940411 2570035	257	2.419	0.0339	No
4	BRD3	6130672	633	1.826	0.0238	No
5	RUNX1	3840711	910	1.531	0.0175	No
6	FLNB	2510575	1305	1.148	0.0026	No
7	ERCC4	1570619 5720180	1393	1.079	0.0040	No
8	GPNMB	1780138 2340176 3390403 4560156	1449	1.040	0.0069	No
9	SYPL1	2680706 5900403	1472	1.026	0.0116	No
10	ATBF1	1240131 7040465	1480	1.023	0.0170	No
11	MYLPF	6110092	1491	1.018	0.0223	No
12	MYO1C	3190398	1591	0.980	0.0225	No
13	RPS15A	1170180	1594	0.977	0.0279	No
14	CRYAB	4810619	1600	0.975	0.0332	No
15	EFNB1	2970433	1732	0.887	0.0311	No
16	LGALS9	1230079 2640181 2970398	1819	0.831	0.0312	No
17	ITGA3	4570427	2002	0.726	0.0254	No
18	MX1	2690301 6840364	2434	0.531	0.0049	No
19	PHF15	6550066 6860673	2460	0.519	0.0065	No
20	PRKAR2B	3130593 5220577	2512	0.501	0.0066	No
21	STX1A	3060273	2552	0.487	0.0072	No
22	ALDH2	4230019	2639	0.460	0.0051	No
23	RPS11	4120403	2640	0.459	0.0078	No
24	PBX2	3130433 6510292	2646	0.458	0.0101	No
25	MPP3	1400056 4480411 6770168	2666	0.452	0.0116	No
26	TIMP3	1450504 1980270	2689	0.443	0.0130	No
27	JUP	2510671	2691	0.443	0.0154	No
28	TGFB3	1070041	2702	0.438	0.0174	No
29	MYO5A	2900288 5270333	2752	0.423	0.0171	No
30	MDK	3840020	3001	0.341	0.0055	No
31	RPL37A	7040717	3075	0.320	0.0034	No
32	LRRC23	3130066 6370504	3100	0.313	0.0039	No
33	RPL39	2370446	3172	0.292	0.0017	No
34	CBS	5420450 6660039	3185	0.289	0.0026	No
35	CREBL1	1340546	3209	0.285	0.0030	No
36	TPT1	3450035	3267	0.273	0.0015	No
37	IL7R	2060088 6380500	3351	0.254	-0.0016	No
38	PSAP	2810338	3411	0.244	-0.0034	No
39	RPS21	3120673	3491	0.226	-0.0065	No
40	COVA1	5340504 5360594	3507	0.223	-0.0060	No
41	NOTCH4	2450040 6370707	3582	0.207	-0.0089	No
42	DAPK1	5570010	3730	0.185	-0.0158	No
43	SLC5A5	3060722	3818	0.172	-0.0196	No
44	GPC1	2640593	3876	0.162	-0.0218	No
45	KISS1	1580398	4015	0.146	-0.0285	No
46	CHN1	6040441	4125	0.134	-0.0337	No
47	ENO2	2320068	4140	0.133	-0.0337	No
48	ITIH4	2690471 4210411	4152	0.131	-0.0335	No
49	BIRC3	6550411	4236	0.125	-0.0374	No
50	AMPD1	3520132	4247	0.123	-0.0372	No
51	HSF4	4610273	4310	0.118	-0.0399	No
52	FEZ1	2630725 4810324	4316	0.117	-0.0395	No
53	WNT10B	510050	4346	0.114	-0.0405	No
54	DDR2	7050273	4458	0.105	-0.0459	No
55	FLT4	1240292 6350707	4478	0.103	-0.0464	No
56	STXBP1	360072 6220717	4489	0.103	-0.0463	No
57	MPZ	1990333	4505	0.101	-0.0466	No
58	TJP1	6350184	4509	0.101	-0.0462	No
59	GPLD1	6100121 6290154	4517	0.100	-0.0460	No
60	PLCB2	360132	4530	0.100	-0.0460	No
61	ADCYAP1	520086	4619	0.094	-0.0503	No
62	PTPRK	1450433 2640142	4760	0.085	-0.0575	No
63	COL14A1	1570398	4762	0.085	-0.0570	No
64	GNG4	2630600	4770	0.085	-0.0569	No
65	IDUA	2690131 4060541	5016	0.072	-0.0699	No
66	FMOD	540577	5053	0.070	-0.0715	No
67	FLT1	3830167 4920438	5111	0.068	-0.0742	No
68	HTR1B	5340133	5185	0.065	-0.0778	No
69	PFN2	730040 5700026	5291	0.060	-0.0832	No
70	SLC10A2	110537	5314	0.060	-0.0841	No
71	RPS16	510722	5335	0.059	-0.0848	No
72	CD24	1780091	5372	0.057	-0.0864	No
73	TNP1	3120048	5411	0.056	-0.0882	No
74	CCR9	580068	5456	0.054	-0.0903	No
75	FOSB	1940142	5598	0.049	-0.0977	No
76	FRZB	2810131	5743	0.044	-0.1053	No
77	HADHB	60064 2690670	5778	0.043	-0.1069	No
78	CDKL5	2450070	5781	0.043	-0.1068	No
79	ALDH7A1	4050446	5782	0.043	-0.1066	No
80	CFTR	1850008	5822	0.042	-0.1084	No
81	BMP4	380113	6000	0.037	-0.1179	No
82	RPL28	6900136	6011	0.036	-0.1182	No
83	ADH4	6840301	6076	0.035	-0.1215	No
84	CES1	1400494	6198	0.032	-0.1280	No
85	YES1	6100050	6373	0.028	-0.1373	No
86	CSF1	3120400	6520	0.025	-0.1451	No
87	RNASE1	6550364	6530	0.025	-0.1455	No
88	MITF	380056	6574	0.024	-0.1477	No
89	ARHGEF16	3990372	6623	0.023	-0.1502	No
90	RPS14	430541	6626	0.022	-0.1502	No
91	GABRA1	130372	6704	0.021	-0.1542	No
92	CXCL12	580546 4150750 4570068	6718	0.020	-0.1548	No
93	NBL1	2480021	6726	0.020	-0.1551	No
94	PAM	5290528	6751	0.020	-0.1563	No
95	IL8RB	450592 1170537	6814	0.019	-0.1596	No
96	CRABP2	6940725	7015	0.015	-0.1704	No
97	TACR3	4780017	7105	0.013	-0.1752	No
98	RBP3	1400059	7112	0.013	-0.1754	No
99	NHLH1	6100452	7191	0.012	-0.1796	No
100	GNB3	1230167	7312	0.009	-0.1861	No
101	CCL22	6380086	7347	0.009	-0.1879	No
102	MMP16	2680139	7379	0.009	-0.1896	No
103	KCNMA1	1450402	7396	0.008	-0.1904	No
104	PTPRN	5900577	7448	0.007	-0.1932	No
105	SLC18A1	840176	7467	0.007	-0.1941	No
106	NCAM1	3140026	7611	0.005	-0.2019	No
107	CALB2	6130170 6590368	7664	0.004	-0.2047	No
108	BTG2	2350411	7705	0.003	-0.2069	No
109	CD34	6650270	7744	0.002	-0.2089	No
110	RGS2	1090736	7777	0.002	-0.2107	No
111	C1S	840184 6840114	7990	-0.002	-0.2222	No
112	PCK1	7000358	8121	-0.004	-0.2293	No
113	QPCT	6180465	8215	-0.005	-0.2343	No
114	MYBPC2	1980368	8229	-0.005	-0.2350	No
115	HOXD10	6100039	8242	-0.006	-0.2356	No
116	MSX1	2650309	8255	-0.006	-0.2363	No
117	ALDH1A1	6520706	8288	-0.006	-0.2380	No
118	TBC1D5	5360619 6130603	8444	-0.009	-0.2464	No
119	ITGA2B	2680538	8507	-0.010	-0.2497	No
120	SLC30A3	1850451	8564	-0.011	-0.2527	No
121	TRAF1	3440735	8773	-0.014	-0.2640	No
122	TLR1	1410524	8842	-0.015	-0.2676	No
123	MME	6040673	9128	-0.020	-0.2831	No
124	AVPR1B	1190707	9188	-0.021	-0.2861	No
125	APOC3	2030168	9315	-0.024	-0.2929	No
126	ADORA3	630333	9367	-0.025	-0.2955	No
127	C4BPA	1690725	9764	-0.031	-0.3170	No
128	OPRM1	5360279	9888	-0.034	-0.3235	No
129	MYL2	70471	9930	-0.035	-0.3255	No
130	ELAVL3	2850014	9971	-0.036	-0.3275	No
131	COL11A1	2100300 2810136 4200706 4810524	10088	-0.038	-0.3336	No
132	PHOX2B	5270075	10099	-0.038	-0.3340	No
133	CYP1A2	5050484	10126	-0.039	-0.3352	No
134	ADRB3	6900072	10157	-0.039	-0.3366	No
135	ITGA8	4050086	10314	-0.042	-0.3449	No
136	CBLB	3520465 4670348	10389	-0.044	-0.3486	No
137	ELA2	1570452 5270129	10402	-0.045	-0.3490	No
138	FUCA1	610075	10520	-0.047	-0.3552	No
139	FCER1G	5550020	10541	-0.047	-0.3560	No
140	B2M	5080332 5130059	10559	-0.048	-0.3566	No
141	CHRM4	1770427	10623	-0.050	-0.3598	No
142	P2RX1	2940021 3290338	10631	-0.050	-0.3599	No
143	HRH1	840100	10698	-0.051	-0.3632	No
144	PAX6	1190025	10723	-0.052	-0.3642	No
145	NR4A1	6290161	10821	-0.054	-0.3692	No
146	TCEAL1	870577	11124	-0.062	-0.3853	No
147	AQP5	3830451	11235	-0.065	-0.3910	No
148	FOLR1	2470369	11248	-0.065	-0.3912	No
149	KLK3	1500278	11272	-0.066	-0.3921	No
150	ACRV1	4070161	11357	-0.069	-0.3963	No
151	AQP2	6370372	11490	-0.072	-0.4031	No
152	AGER	5860538 5910180	11582	-0.075	-0.4077	No
153	CACNA1B	1740010 5360593	11890	-0.086	-0.4239	No
154	CXADR	6370068	12026	-0.091	-0.4308	No
155	FEV	840369 5860139	12058	-0.093	-0.4319	No
156	CDH15	460014	12175	-0.098	-0.4377	No
157	CD40	2760471 2940390 6220402 6220452	12258	-0.101	-0.4416	No
158	SMAD1	630537 1850333	12263	-0.102	-0.4412	No
159	TCL1A	3420367	12280	-0.102	-0.4415	No
160	DMD	1740041 3990332	12380	-0.107	-0.4463	No
161	LTBP2	4850039	12393	-0.108	-0.4464	No
162	JUN	840170	12506	-0.114	-0.4518	No
163	APOC2	50100	12697	-0.123	-0.4615	No
164	RAPGEF5	1500603 3450427 6130056	12707	-0.124	-0.4613	No
165	ITGAX	6130524	12782	-0.129	-0.4646	No
166	PALM	130601 3850017	12818	-0.131	-0.4658	No
167	SPRR1A	3870064	12840	-0.132	-0.4661	No
168	RPS18	670132 1230148 2030722	12858	-0.133	-0.4663	No
169	HHEX	2340575	12925	-0.138	-0.4691	No
170	GZMA	3390315	13040	-0.145	-0.4745	No
171	MIA3	3710092 5130711 5550746	13097	-0.149	-0.4767	No
172	PPAP2B	3190397 4730280	13206	-0.156	-0.4817	No
173	HTR2C	380497	13400	-0.172	-0.4913	No
174	MC4R	430333	13416	-0.173	-0.4911	No
175	CNTNAP1	6650132	13457	-0.177	-0.4923	No
176	GCM1	6510687	13524	-0.183	-0.4949	No
177	CD22	3120239	13592	-0.190	-0.4974	No
178	AK1	130605	13622	-0.192	-0.4979	No
179	VPREB1	3520280	13725	-0.202	-0.5023	No
180	HOXB13	4730152	13802	-0.210	-0.5053	No
181	HOXB2	6450592	13804	-0.210	-0.5041	No
182	ACTC1	2340021 5220465	13916	-0.222	-0.5089	No
183	MERTK	6420056	13952	-0.226	-0.5095	No
184	WWOX	510008 870524 1090114	14050	-0.236	-0.5135	No
185	FABP3	6860452	14124	-0.245	-0.5161	No
186	CD3E	3800056	14211	-0.258	-0.5193	No
187	SCN1B	1240022 2120048	14215	-0.259	-0.5180	No
188	RAB13	3710309	14283	-0.267	-0.5201	No
189	RPS2	1340647	14301	-0.269	-0.5195	No
190	CYFIP1	5690082	14333	-0.273	-0.5196	No
191	SPINT2	2630039 6110519	14415	-0.284	-0.5224	No
192	TNC	670053 1780039 1980020 3060411 4780091 6860433	14477	-0.295	-0.5241	No
193	PCOLCE	4210433	14507	-0.300	-0.5240	No
194	PDE4A	1190619 1340129 5720100 6370035	14595	-0.316	-0.5269	No
195	PCSK6	520097	14610	-0.320	-0.5258	No
196	SPRR2A	360632	14627	-0.322	-0.5249	No
197	GZMM	540603	14663	-0.328	-0.5249	No
198	RPL7A	5420458	14664	-0.328	-0.5230	No
199	NELL2	2340725 4280301 5420008	14698	-0.335	-0.5229	No
200	PTGDS	3610519	14701	-0.335	-0.5211	No
201	CPB1	290600	14761	-0.345	-0.5224	No
202	TNFAIP2	70438 1740215	14821	-0.354	-0.5236	No
203	SORL1	630204	14932	-0.377	-0.5274	No
204	FOS	1850315	14971	-0.386	-0.5273	No
205	TNFAIP3	2900142	15056	-0.405	-0.5296	Yes
206	DDR1	2060044 5220180	15087	-0.411	-0.5289	Yes
207	MAG	2370037	15125	-0.419	-0.5285	Yes
208	COL1A1	730020	15140	-0.422	-0.5269	Yes
209	GRN	4050239	15170	-0.428	-0.5260	Yes
210	DPP6	5810368	15176	-0.429	-0.5238	Yes
211	ACTB	1660736 2030204 2060215 5050047	15190	-0.433	-0.5221	Yes
212	MCAM	5130270 6620577	15210	-0.437	-0.5206	Yes
213	LRP1	6270386	15273	-0.453	-0.5214	Yes
214	GPR30	7570008	15281	-0.455	-0.5192	Yes
215	ALOX5AP	3170440	15284	-0.455	-0.5167	Yes
216	FBN1	3170181	15304	-0.461	-0.5151	Yes
217	IL4R	2370520	15314	-0.463	-0.5130	Yes
218	MMP9	580338	15380	-0.483	-0.5138	Yes
219	RPLP1	3140292	15411	-0.493	-0.5126	Yes
220	ADAM8	450347 5670609	15539	-0.535	-0.5165	Yes
221	SLC15A2	1780538	15567	-0.545	-0.5148	Yes
222	DAB2	60309	15583	-0.551	-0.5125	Yes
223	TCN2	2810139	15585	-0.552	-0.5094	Yes
224	LTC4S	2570411	15603	-0.561	-0.5071	Yes
225	CHERP	1240594	15610	-0.565	-0.5042	Yes
226	RPL18A	4570619	15644	-0.574	-0.5028	Yes
227	PHB2	1230050	15708	-0.597	-0.5028	Yes
228	ITPKB	2900195 7100039	15850	-0.642	-0.5068	Yes
229	OAZ1	110181	16022	-0.724	-0.5120	Yes
230	SGSH	6180717	16055	-0.740	-0.5096	Yes
231	COL4A1	1740575	16097	-0.756	-0.5075	Yes
232	KCNQ1	1580050 6860441	16104	-0.761	-0.5035	Yes
233	NFIC	5690026	16153	-0.775	-0.5017	Yes
234	MGST2	2650129	16183	-0.788	-0.4987	Yes
235	CPA3	610242 6380102	16273	-0.834	-0.4988	Yes
236	VCAM1	2900450	16311	-0.852	-0.4960	Yes
237	SSR4	1340619 4150132	16314	-0.856	-0.4912	Yes
238	SLC14A2	3290086 4760056	16322	-0.857	-0.4867	Yes
239	FSTL1	2900113	16327	-0.861	-0.4820	Yes
240	CST3	7050452	16344	-0.869	-0.4779	Yes
241	PPM1F	770687 1240592	16388	-0.890	-0.4752	Yes
242	FGR	3780047	16411	-0.899	-0.4713	Yes
243	HEXA	2630358	16426	-0.905	-0.4669	Yes
244	RAB32	6040358	16503	-0.941	-0.4657	Yes
245	SNCA	5340673	16555	-0.967	-0.4629	Yes
246	CD9	4730041	16660	-1.005	-0.4629	Yes
247	IFITM1	1690601 3120438 6510075	16701	-1.022	-0.4592	Yes
248	SIRPA	130465 5700332	16718	-1.028	-0.4542	Yes
249	MPO	2360176 2760440 5690176	16754	-1.045	-0.4502	Yes
250	BCR	2260020 4230180 6040195	16775	-1.059	-0.4452	Yes
251	NFKB2	2320670	16799	-1.069	-0.4404	Yes
252	S100A9	7050528	16846	-1.091	-0.4367	Yes
253	NFKBIA	1570152	16859	-1.101	-0.4310	Yes
254	S100A8	70112	16885	-1.127	-0.4260	Yes
255	UROD	2470494	17015	-1.206	-0.4261	Yes
256	LCN2	2510112	17048	-1.231	-0.4208	Yes
257	CD3D	2810739	17073	-1.243	-0.4151	Yes
258	TIAM1	5420288	17075	-1.244	-0.4080	Yes
259	ADM	4810121	17111	-1.264	-0.4027	Yes
260	HP	2940551 6350068	17126	-1.271	-0.3962	Yes
261	CFB	730577	17337	-1.416	-0.3996	Yes
262	HIST1H4I	2190450	17360	-1.430	-0.3926	Yes
263	CUL7	3360114	17410	-1.468	-0.3869	Yes
264	IGFBP4	2680309 5420441	17474	-1.506	-0.3818	Yes
265	RELB	1400048	17499	-1.525	-0.3744	Yes
266	CCR7	2060687	17540	-1.557	-0.3677	Yes
267	IKBKE	1850332	17553	-1.566	-0.3594	Yes
268	SMPDL3B	2350072	17608	-1.609	-0.3532	Yes
269	FCGRT	5130315	17645	-1.643	-0.3458	Yes
270	RBPMS	3990494	17716	-1.713	-0.3398	Yes
271	TPM1	130673	17733	-1.728	-0.3308	Yes
272	SERPING1	5550440	17774	-1.761	-0.3229	Yes
273	SMPD1	1410309 5550717	17778	-1.768	-0.3130	Yes
274	TBXA2R	2370292 3940066	17812	-1.808	-0.3045	Yes
275	FBP1	1470762	17854	-1.846	-0.2962	Yes
276	HSPB1	6760435	17866	-1.859	-0.2862	Yes
277	FSCN1	3450463	17928	-1.922	-0.2786	Yes
278	GAA	520035	17934	-1.928	-0.2678	Yes
279	EGR1	4610347	17946	-1.942	-0.2573	Yes
280	CTLA4	6590537	17971	-1.974	-0.2474	Yes
281	HERPUD1	7100440	18010	-2.016	-0.2379	Yes
282	PIK3R2	1660193	18023	-2.025	-0.2270	Yes
283	CD72	2340369	18111	-2.130	-0.2196	Yes
284	CYBA	4760739	18125	-2.152	-0.2081	Yes
285	GMPR	3990022	18136	-2.160	-0.1963	Yes
286	GNA11	2760156 6550671 7100068	18154	-2.182	-0.1848	Yes
287	APOC1	5900066 6220408	18213	-2.272	-0.1750	Yes
288	CIRBP	1850408	18234	-2.305	-0.1629	Yes
289	GPX3	1340450	18260	-2.360	-0.1508	Yes
290	LGMN	3610301	18316	-2.444	-0.1398	Yes
291	HES1	4810280	18347	-2.504	-0.1272	Yes
292	SDC1	3440471 6350408	18361	-2.549	-0.1133	Yes
293	APOE	4200671	18370	-2.578	-0.0991	Yes
294	CLU	5420075	18405	-2.667	-0.0857	Yes
295	GPR18	2640551	18482	-2.913	-0.0732	Yes
296	LST1	5420372	18533	-3.189	-0.0578	Yes
297	AEBP1	6450707	18555	-3.312	-0.0400	Yes
298	DUSP1	6860121	18587	-3.727	-0.0204	Yes
299	MAPKAPK2	2850500	18590	-3.846	0.0014	Yes