Details for gene set ICHIBA

Table: GSEA Results Summary

Dataset	Set_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls #wtNotch_versus_truncNotch.phenotype_truncNotch_versus_wtNotch.cls #wtNotch_versus_truncNotch_repos
Phenotype	phenotype_truncNotch_versus_wtNotch.cls#wtNotch_versus_truncNotch_repos
Upregulated in class	truncNotch
GeneSet	ICHIBA_GVHD
Enrichment Score (ES)	-0.54792726
Normalized Enrichment Score (NES)	-1.6833491
Nominal p-value	0.0
FDR q-value	0.117941275
FWER p-Value	0.57

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	PKM2	6520403 70500	69	3.058	0.0111	No
2	TAP2	2810347	201	2.534	0.0162	No
3	ATP1B3	6040128	368	2.191	0.0178	No
4	1500011J06RIK	5130056	415	2.112	0.0256	No
5	EXOSC8	360427	598	1.862	0.0247	No
6	PTPRC	130402 5290148	788	1.663	0.0224	No
7	ELOVL6	5340746	816	1.633	0.0289	No
8	IQGAP1	6660494	854	1.591	0.0346	No
9	MCM4	2760673 5420711	904	1.538	0.0394	No
10	FKBP5	2190048	907	1.535	0.0467	No
11	EIF1	5080100	1215	1.230	0.0360	No
12	4921506I22RIK	1340279	1218	1.228	0.0418	No
13	BC004022	3440142	1397	1.075	0.0373	No
14	SMOC2	1170170	1423	1.055	0.0411	No
15	ICAM1	6980138	1452	1.039	0.0446	No
16	ACSL1	2900520	1505	1.010	0.0467	No
17	LYZS	50068 6770717	1542	0.999	0.0496	No
18	USP18	4010110	1648	0.941	0.0484	No
19	IFI47	3060673	1756	0.874	0.0468	No
20	UCK1	2650398 3130113 5130725	1788	0.853	0.0493	No
21	RPAP1	4670152 6450068	1799	0.848	0.0528	No
22	NCF4	610164	1800	0.844	0.0569	No
23	POM121	70152	1813	0.838	0.0603	No
24	PSME1	450193 4480035	1836	0.823	0.0631	No
25	NEK9	3440402	1853	0.811	0.0662	No
26	BIRC5	110408 580014 1770632	1894	0.790	0.0679	No
27	LPL	1450735 2970706	1943	0.762	0.0689	No
28	9830147J24RIK	2690451	2055	0.688	0.0662	No
29	AIM1	2810142	2147	0.647	0.0644	No
30	1700013L23RIK	3390097	2203	0.622	0.0644	No
31	GLTP	3440603	2325	0.573	0.0606	No
32	PSME2	4850086	2451	0.523	0.0563	No
33	STAT1	6510204 6590553	2575	0.480	0.0519	No
34	LY6A	6110605	2578	0.479	0.0542	No
35	HMGCS2	770725	2645	0.458	0.0528	No
36	LY86	2230093	2725	0.433	0.0506	No
37	SPTLC2	6840324 520017	2773	0.416	0.0500	No
38	SNX10	3800035	2776	0.415	0.0519	No
39	IL6ST	5890047	2796	0.409	0.0529	No
40	AIF1	130332 5220017	2913	0.369	0.0484	No
41	STX3	1190563 2640215	3036	0.330	0.0433	No
42	PPP1R2	3710278 1400725	3037	0.329	0.0449	No
43	UBAP2L	4120128 6650133	3065	0.321	0.0450	No
44	ADCY9	5690168	3068	0.321	0.0464	No
45	CD52	5910242	3091	0.315	0.0468	No
46	NR2F6	1340239 5670239 60338 4280088	3300	0.265	0.0367	No
47	NCOA3	4540195	3304	0.265	0.0378	No
48	PAPSS2	870113	3314	0.263	0.0386	No
49	GLT25D1	540088	3430	0.238	0.0335	No
50	XDH	6840446	3497	0.225	0.0310	No
51	NFKBIZ	2970450	3627	0.200	0.0249	No
52	MMP12	4920070	3649	0.198	0.0247	No
53	MARVELD1	6110309	3750	0.181	0.0202	No
54	CDC5L	3130446 3390025 6400204	3771	0.177	0.0199	No
55	PBEF1	1090278	3842	0.168	0.0169	No
56	ATP11A	1240717 5570603	4048	0.141	0.0064	No
57	RPL22	4070070	4054	0.141	0.0069	No
58	GP49A	1940390	4098	0.136	0.0052	No
59	APBB1IP	4560441 4570706 6520739	4118	0.135	0.0048	No
60	LCP2	2680066 6650707	4134	0.134	0.0046	No
61	CHI3L3	2120332	4201	0.127	0.0016	No
62	LY75	1990358 4590136	4204	0.127	0.0021	No
63	CSF1R	2340110 6420408	4246	0.124	0.0005	No
64	OAT	540632	4428	0.107	-0.0088	No
65	GBP4	6520471 1980670	4503	0.102	-0.0124	No
66	PPP1R3C	2640170	4746	0.086	-0.0252	No
67	UBD	5570632	4753	0.086	-0.0251	No
68	LRG1	5690605	4803	0.083	-0.0274	No
69	GDF5	510440	4883	0.078	-0.0313	No
70	FPR1	3800577	4930	0.076	-0.0334	No
71	AVPR1A	2120300	4939	0.076	-0.0335	No
72	H2-EA	3870301	5017	0.072	-0.0373	No
73	MUP4	670253 4560487	5089	0.069	-0.0409	No
74	DIO1	4570279 5290112 5420148	5226	0.063	-0.0480	No
75	MCM10	4920632	5254	0.062	-0.0492	No
76	MSR1	940538	5308	0.060	-0.0518	No
77	CRYAA	2030164	5429	0.055	-0.0580	No
78	SERPINA6	1850707	5434	0.055	-0.0580	No
79	SC5DL	6650390	5758	0.044	-0.0754	No
80	VNN1	3940400	5761	0.043	-0.0753	No
81	CCL2	4760019	5831	0.042	-0.0789	No
82	GAS1	2120504	5869	0.041	-0.0807	No
83	KLF10	4850056	5971	0.038	-0.0860	No
84	CES3	5050167 3290458	6115	0.034	-0.0936	No
85	ORM1	1500563	6117	0.034	-0.0935	No
86	LIFR	3360068 3830102	6164	0.033	-0.0959	No
87	PDK3	510484	6246	0.031	-0.1001	No
88	A130022J15RIK	4150494	6272	0.030	-0.1014	No
89	MUP3	4480152	6327	0.029	-0.1042	No
90	ODZ3	3060725 6450292	6381	0.028	-0.1069	No
91	PRLR	1980647 1990097	6447	0.026	-0.1103	No
92	CYP2B9	360152	6543	0.024	-0.1154	No
93	CASP6	5690239 6420551	6688	0.021	-0.1232	No
94	HSD3B3	4570113	6689	0.021	-0.1230	No
95	PIRA1	4120632	6731	0.020	-0.1252	No
96	HAO3	6100368	6782	0.019	-0.1278	No
97	FABP1	6940035	6792	0.019	-0.1282	No
98	IFIT1	5270373	6894	0.017	-0.1336	No
99	GIMAP4	5570673 6550041	6944	0.016	-0.1362	No
100	TLR6	510102 3390148	7006	0.015	-0.1395	No
101	ZIC3	380020	7084	0.013	-0.1436	No
102	IFIT3	2450278 3190113 6200113	7100	0.013	-0.1444	No
103	H2-D1	2190725	7242	0.011	-0.1520	No
104	HSD17B2	3800541	7244	0.010	-0.1520	No
105	IFI202B	4070398	7272	0.010	-0.1534	No
106	PAX3	50551	7369	0.009	-0.1586	No
107	DCLRE1A	5890427	7370	0.009	-0.1586	No
108	5830411E10RIK	2940053	7585	0.005	-0.1702	No
109	LIPC	2690497	7692	0.003	-0.1760	No
110	BTG2	2350411	7705	0.003	-0.1767	No
111	PSCDBP	1780408	7800	0.002	-0.1818	No
112	PROCR	4920687	7852	0.001	-0.1845	No
113	ACTL7B	460341	7864	0.001	-0.1851	No
114	IL1RN	2370333	7976	-0.001	-0.1912	No
115	SULT2A2	2650397	7993	-0.002	-0.1921	No
116	CAR14	1450528	8330	-0.007	-0.2103	No
117	GSTM6	3940358 5670019	8395	-0.008	-0.2138	No
118	KEG1	6940603	8494	-0.010	-0.2191	No
119	CCL6	6660390	8525	-0.010	-0.2207	No
120	PKLR	1170400 2470114	8549	-0.011	-0.2219	No
121	TGTP	2810138	8640	-0.012	-0.2267	No
122	RPS6KC1	5220619	8666	-0.013	-0.2280	No
123	TMSB4X	6620114	8778	-0.014	-0.2340	No
124	CXCL10	2450408	8852	-0.016	-0.2379	No
125	HSD3B2	70068 770037 4120114 4230170 5690333	9296	-0.023	-0.2620	No
126	GBP2	50301	9492	-0.027	-0.2725	No
127	MUP5	6770279	9638	-0.029	-0.2802	No
128	ELOVL2	5720064	9710	-0.030	-0.2840	No
129	FGL2	3170731	9711	-0.030	-0.2838	No
130	GHR	2260156	9739	-0.031	-0.2851	No
131	RELN	6510037	10081	-0.038	-0.3036	No
132	ADRB3	6900072	10157	-0.039	-0.3075	No
133	GBP1	780075	10654	-0.050	-0.3343	No
134	SLC26A1	2190142	10715	-0.052	-0.3373	No
135	CYP7B1	1190309	10716	-0.052	-0.3370	No
136	CYP4A10	3170288 6130131	10733	-0.052	-0.3377	No
137	SH3GL1	6110154	10885	-0.056	-0.3456	No
138	CD5L	4070605	11143	-0.062	-0.3593	No
139	CTLA2B	4210168	11188	-0.064	-0.3614	No
140	CYP2B13	5420672	11269	-0.066	-0.3655	No
141	MS4A4D	4850632	11443	-0.071	-0.3746	No
142	PSMB9	6980471	11460	-0.072	-0.3751	No
143	SLC1A2	2230520	11915	-0.087	-0.3994	No
144	LBP	6860019	12019	-0.091	-0.4046	No
145	SAA2	1090139	12084	-0.094	-0.4076	No
146	CYP26A1	380022 2690600	12092	-0.094	-0.4076	No
147	HCK	4230592	12176	-0.098	-0.4116	No
148	IL18R1	270546	12245	-0.101	-0.4148	No
149	SULT4A1	5270161	12372	-0.107	-0.4212	No
150	ORM3	3310128	12409	-0.109	-0.4226	No
151	ORM2	2100048	12414	-0.109	-0.4223	No
152	SERPINA10	2360114	12529	-0.115	-0.4280	No
153	BMPR2	5340066 6960328	12836	-0.132	-0.4440	No
154	SCMH1	3190019 6770450	12901	-0.136	-0.4469	No
155	PTGS1	730193 1780273 6450195	13052	-0.146	-0.4543	No
156	PLK1	1780369 2640121	13227	-0.159	-0.4631	No
157	SCD5	5690309 5220332 7040278	13269	-0.161	-0.4645	No
158	CASP1	2360546	13402	-0.172	-0.4709	No
159	OSBPL5	3840537 6040286	13542	-0.184	-0.4776	No
160	IGFALS	6350195	13549	-0.185	-0.4770	No
161	CYP2B10	3390100	13582	-0.188	-0.4778	No
162	KRT1-18	4060563	13598	-0.190	-0.4777	No
163	NNMT	450471	13621	-0.192	-0.4780	No
164	S100A11	2260064	13646	-0.194	-0.4783	No
165	MKLN1	70504 1850129	13702	-0.200	-0.4804	No
166	SAMHD1	2350338 5390451	13762	-0.207	-0.4826	No
167	FCGR1	6100176	13774	-0.208	-0.4822	No
168	CYBB	3870020	13806	-0.210	-0.4828	No
169	FAS	4480112 6110040	14139	-0.247	-0.4998	No
170	CXCL9	1570673	14178	-0.253	-0.5006	No
171	MARCO	870056	14205	-0.258	-0.5008	No
172	CYP8B1	2350369	14359	-0.276	-0.5078	No
173	LPHN1	1400113 3130301	14510	-0.301	-0.5145	No
174	NR1D1	2360471 770746 6590204	14570	-0.313	-0.5162	No
175	PROM1	3170537	14670	-0.329	-0.5200	No
176	ITGB2	6380348	14717	-0.338	-0.5209	No
177	CXCL1	2690537	14790	-0.349	-0.5231	No
178	CTSS	1740056	14794	-0.349	-0.5216	No
179	CCR1	3440672	14924	-0.375	-0.5268	No
180	MS4A6C	3870427	14976	-0.387	-0.5277	No
181	EMR1	70136 1500592	15039	-0.402	-0.5291	No
182	D17H6S56E-5	4760095	15164	-0.426	-0.5338	No
183	GRN	4050239	15170	-0.428	-0.5320	No
184	AKAP9	510184 2060195 2470136 4280048	15191	-0.433	-0.5310	No
185	NAT8	6520500	15483	-0.517	-0.5444	No
186	IRF8	610161	15503	-0.522	-0.5429	No
187	SOCS1	730139	15597	-0.558	-0.5452	Yes
188	IRGM	6110148 6660685	15625	-0.567	-0.5439	Yes
189	NOL1	4570576 4920044	15665	-0.583	-0.5432	Yes
190	PSMB10	630504 6510039	15732	-0.604	-0.5439	Yes
191	CTSE	2030292	15761	-0.614	-0.5424	Yes
192	ELAC2	3440167 4730546	15763	-0.614	-0.5395	Yes
193	LAPTM5	5550372	15782	-0.622	-0.5375	Yes
194	TMSB10	2340484	15794	-0.626	-0.5350	Yes
195	FKBP11	3170575	15812	-0.631	-0.5329	Yes
196	CD7	3140465	15820	-0.633	-0.5302	Yes
197	MT1A	4850164	15829	-0.636	-0.5276	Yes
198	SAA3P	6510390	15830	-0.637	-0.5245	Yes
199	PRM3	4810577	15863	-0.649	-0.5231	Yes
200	HPXN	3440114	15976	-0.701	-0.5258	Yes
201	G6PC	430093	16006	-0.716	-0.5239	Yes
202	SELPL	1770167	16010	-0.717	-0.5206	Yes
203	COL4A1	1740575	16097	-0.756	-0.5216	Yes
204	ITPK1	3360056	16180	-0.787	-0.5222	Yes
205	1110038F14RIK	1190075	16204	-0.798	-0.5196	Yes
206	VCAM1	2900450	16311	-0.852	-0.5213	Yes
207	CFP	2100619	16342	-0.868	-0.5187	Yes
208	D12ERTD647E	5290364	16409	-0.898	-0.5179	Yes
209	LITAF	6940671	16484	-0.932	-0.5174	Yes
210	LGALS3	2120239	16534	-0.958	-0.5155	Yes
211	CTSC	2230739 4670408	16574	-0.976	-0.5129	Yes
212	CLIC1	110600	16583	-0.981	-0.5085	Yes
213	CD14	5570600	16594	-0.987	-0.5043	Yes
214	IL18BP	3450128	16647	-1.000	-0.5023	Yes
215	WARS	2570717 3290139	16662	-1.005	-0.4981	Yes
216	H2-AB1	4230427	16711	-1.025	-0.4958	Yes
217	CTPS	70451 1740132	16714	-1.027	-0.4909	Yes
218	SIRPA	130465 5700332	16718	-1.028	-0.4861	Yes
219	PRTN3	6900670	16734	-1.035	-0.4819	Yes
220	LCK	3360142	16840	-1.087	-0.4823	Yes
221	S100A9	7050528	16846	-1.091	-0.4773	Yes
222	RRAS	4150609	16850	-1.094	-0.4722	Yes
223	SLPI	2120446	16855	-1.098	-0.4670	Yes
224	NFKBIA	1570152	16859	-1.101	-0.4619	Yes
225	S100A8	70112	16885	-1.127	-0.4577	Yes
226	S100A4	3780113	16970	-1.175	-0.4566	Yes
227	CD53	5550162	16976	-1.178	-0.4512	Yes
228	LTF	6770364	17004	-1.200	-0.4468	Yes
229	C1QB	5910292	17030	-1.214	-0.4423	Yes
230	HBB-B2	2450131	17087	-1.252	-0.4393	Yes
231	HP	2940551 6350068	17126	-1.271	-0.4352	Yes
232	NGP	2640133	17158	-1.300	-0.4306	Yes
233	CCL4	50368 430047	17242	-1.353	-0.4285	Yes
234	SLFN2	3120114	17268	-1.370	-0.4232	Yes
235	H2-EB1	2350079	17285	-1.379	-0.4174	Yes
236	IRF1	2340152 3450592 6290121 6980577	17303	-1.388	-0.4116	Yes
237	CCL5	3710397	17387	-1.453	-0.4091	Yes
238	MT2A	6860286	17389	-1.456	-0.4021	Yes
239	IRF7	1570605	17457	-1.493	-0.3985	Yes
240	S100A6	1690204	17470	-1.504	-0.3918	Yes
241	CD68	6350450	17507	-1.529	-0.3864	Yes
242	CCL7	2650519	17523	-1.539	-0.3797	Yes
243	HBA-A1	360435	17549	-1.564	-0.3735	Yes
244	FBXO21	6550070	17565	-1.576	-0.3666	Yes
245	TAPBP	1980110	17570	-1.580	-0.3592	Yes
246	ALAS2	6550176	17594	-1.598	-0.3527	Yes
247	CAMP	6290735	17599	-1.602	-0.3451	Yes
248	HES6	540411 6550504	17603	-1.605	-0.3375	Yes
249	C1QA	5390687	17695	-1.694	-0.3342	Yes
250	C1QC	5700131	17801	-1.798	-0.3312	Yes
251	PDZK1	2320128	17822	-1.822	-0.3235	Yes
252	PLD3	510041	17839	-1.835	-0.3154	Yes
253	PTPN1	2650056	17869	-1.862	-0.3080	Yes
254	H2-AA	5290673	17920	-1.916	-0.3014	Yes
255	PSMB8	2850707	17924	-1.918	-0.2923	Yes
256	SLC25A10	1400609	17925	-1.919	-0.2829	Yes
257	CRYL1	1340427	17941	-1.935	-0.2744	Yes
258	TFF3	1580129	17978	-1.979	-0.2667	Yes
259	ELA1	3390167	18026	-2.030	-0.2594	Yes
260	H2-DMB1	4760026	18041	-2.040	-0.2503	Yes
261	SERPINA3G	610600	18046	-2.055	-0.2405	Yes
262	CYBA	4760739	18125	-2.152	-0.2343	Yes
263	ISG15	3170093	18149	-2.176	-0.2250	Yes
264	CYB561	5080341	18162	-2.190	-0.2150	Yes
265	TAP1	4050047	18244	-2.324	-0.2082	Yes
266	GPX3	1340450	18260	-2.360	-0.1975	Yes
267	QSCN6	3120441	18294	-2.408	-0.1877	Yes
268	LGMN	3610301	18316	-2.444	-0.1769	Yes
269	IFI35	4230739	18355	-2.526	-0.1667	Yes
270	TYROBP	2230020	18358	-2.536	-0.1545	Yes
271	TSPAN4	5050647	18382	-2.604	-0.1432	Yes
272	NXN	2350180	18389	-2.620	-0.1308	Yes
273	UBE1L	6660242	18390	-2.625	-0.1180	Yes
274	VEGFB	5360152	18429	-2.750	-0.1067	Yes
275	SNX12	4060026	18452	-2.822	-0.0942	Yes
276	FLOT1	1660575 1690040	18456	-2.827	-0.0807	Yes
277	LGALS3BP	840692	18481	-2.909	-0.0679	Yes
278	SCOTIN	670332 3450167 6450022	18491	-2.932	-0.0541	Yes
279	H2-DMA	6290463	18507	-3.020	-0.0403	Yes
280	PLAC8	2900019	18509	-3.022	-0.0257	Yes
281	KLF2	6860270	18512	-3.049	-0.0110	Yes
282	SLC11A1	940286 2810435 6370647	18565	-3.418	0.0028	Yes