Dataset | Set_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls #wtNotch_versus_truncNotch.phenotype_truncNotch_versus_wtNotch.cls #wtNotch_versus_truncNotch_repos |
Phenotype | phenotype_truncNotch_versus_wtNotch.cls#wtNotch_versus_truncNotch_repos |
Upregulated in class | wtNotch |
GeneSet | ET743_SARCOMA_DN |
Enrichment Score (ES) | 0.5671204 |
Normalized Enrichment Score (NES) | 1.8280684 |
Nominal p-value | 0.0 |
FDR q-value | 0.04593928 |
FWER p-Value | 0.112 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | SLC4A1AP | 3190576 | 14 | 3.866 | 0.0230 | Yes | ||
2 | LBR | 4540671 | 26 | 3.582 | 0.0444 | Yes | ||
3 | CCT4 | 6380161 | 71 | 3.052 | 0.0607 | Yes | ||
4 | OGT | 2360131 4610333 | 109 | 2.829 | 0.0761 | Yes | ||
5 | PSMD14 | 5690593 | 119 | 2.806 | 0.0928 | Yes | ||
6 | EP400 | 3940722 | 129 | 2.757 | 0.1093 | Yes | ||
7 | RAB1A | 2370671 | 140 | 2.727 | 0.1255 | Yes | ||
8 | RABGGTB | 3120037 | 152 | 2.678 | 0.1413 | Yes | ||
9 | DDX20 | 3290348 | 162 | 2.649 | 0.1571 | Yes | ||
10 | PSMA4 | 4560427 | 198 | 2.539 | 0.1708 | Yes | ||
11 | RPP14 | 7040014 | 234 | 2.470 | 0.1841 | Yes | ||
12 | RABGAP1 | 5050397 | 236 | 2.466 | 0.1991 | Yes | ||
13 | DCK | 6900411 | 241 | 2.451 | 0.2140 | Yes | ||
14 | SFRS3 | 770315 4230593 | 276 | 2.375 | 0.2267 | Yes | ||
15 | CCNH | 3190347 | 309 | 2.289 | 0.2390 | Yes | ||
16 | RIPK1 | 3190025 | 325 | 2.264 | 0.2521 | Yes | ||
17 | PRKACB | 4210170 | 339 | 2.235 | 0.2651 | Yes | ||
18 | AOF2 | 2060300 | 343 | 2.228 | 0.2787 | Yes | ||
19 | TBK1 | 5690338 | 348 | 2.222 | 0.2921 | Yes | ||
20 | SLC25A17 | 2100369 | 370 | 2.189 | 0.3044 | Yes | ||
21 | HDAC2 | 4050433 | 372 | 2.188 | 0.3178 | Yes | ||
22 | FNTA | 70059 | 409 | 2.120 | 0.3288 | Yes | ||
23 | DDX21 | 6100446 | 442 | 2.073 | 0.3398 | Yes | ||
24 | GTF2H2 | 5130358 | 445 | 2.069 | 0.3524 | Yes | ||
25 | PJA2 | 430537 | 470 | 2.037 | 0.3636 | Yes | ||
26 | PCNA | 940754 | 526 | 1.941 | 0.3726 | Yes | ||
27 | MAP3K7 | 6040068 | 534 | 1.929 | 0.3840 | Yes | ||
28 | UBE2D3 | 3190452 | 542 | 1.915 | 0.3954 | Yes | ||
29 | POLD3 | 6400278 | 553 | 1.899 | 0.4065 | Yes | ||
30 | SRPK2 | 6380341 | 580 | 1.872 | 0.4166 | Yes | ||
31 | NET1 | 2900707 | 590 | 1.867 | 0.4276 | Yes | ||
32 | RAP1B | 3710138 | 599 | 1.861 | 0.4386 | Yes | ||
33 | TNFSF5IP1 | 2060095 | 604 | 1.858 | 0.4498 | Yes | ||
34 | STAU1 | 2320494 | 616 | 1.845 | 0.4605 | Yes | ||
35 | MCTS1 | 6130133 | 636 | 1.821 | 0.4707 | Yes | ||
36 | OSBPL9 | 2570373 | 728 | 1.715 | 0.4763 | Yes | ||
37 | PPP2R5E | 70671 2120056 | 738 | 1.710 | 0.4863 | Yes | ||
38 | ELOVL6 | 5340746 | 816 | 1.633 | 0.4921 | Yes | ||
39 | TOP2A | 360717 | 909 | 1.531 | 0.4965 | Yes | ||
40 | XBP1 | 3840594 | 939 | 1.491 | 0.5041 | Yes | ||
41 | TMPO | 4050494 | 943 | 1.489 | 0.5131 | Yes | ||
42 | GTF2B | 6860685 | 1105 | 1.328 | 0.5125 | Yes | ||
43 | RBM17 | 870592 | 1168 | 1.265 | 0.5169 | Yes | ||
44 | HSPH1 | 1690017 | 1169 | 1.265 | 0.5247 | Yes | ||
45 | SIRT1 | 1190731 | 1245 | 1.201 | 0.5280 | Yes | ||
46 | SUPV3L1 | 1170072 | 1287 | 1.165 | 0.5329 | Yes | ||
47 | MAPK14 | 5290731 | 1301 | 1.150 | 0.5393 | Yes | ||
48 | AURKA | 780537 | 1317 | 1.140 | 0.5455 | Yes | ||
49 | UBE2D2 | 4590671 6510446 | 1363 | 1.102 | 0.5498 | Yes | ||
50 | TXNRD1 | 6590446 | 1371 | 1.098 | 0.5561 | Yes | ||
51 | BTG1 | 4200735 6040131 6200133 | 1533 | 1.000 | 0.5535 | Yes | ||
52 | MAT2A | 4070026 4730079 6020280 | 1555 | 0.995 | 0.5585 | Yes | ||
53 | EML4 | 5700373 | 1651 | 0.941 | 0.5591 | Yes | ||
54 | FADD | 2360593 4210692 6520019 | 1712 | 0.901 | 0.5614 | Yes | ||
55 | STK17B | 130091 | 1757 | 0.874 | 0.5644 | Yes | ||
56 | CDK5R1 | 3870161 | 1949 | 0.758 | 0.5587 | Yes | ||
57 | BIRC2 | 2940435 4730020 | 1953 | 0.757 | 0.5632 | Yes | ||
58 | CRLF3 | 6620019 | 2067 | 0.685 | 0.5612 | Yes | ||
59 | CCNA2 | 5290075 | 2176 | 0.634 | 0.5593 | Yes | ||
60 | ZDHHC5 | 1690711 | 2257 | 0.598 | 0.5586 | Yes | ||
61 | RCOR1 | 5360717 | 2285 | 0.587 | 0.5607 | Yes | ||
62 | PSMC6 | 2810021 | 2356 | 0.560 | 0.5604 | Yes | ||
63 | ERCC3 | 6900008 | 2382 | 0.551 | 0.5624 | Yes | ||
64 | GABPB2 | 6130450 7050735 | 2416 | 0.538 | 0.5639 | Yes | ||
65 | PSME3 | 2810537 | 2475 | 0.515 | 0.5639 | Yes | ||
66 | SRRM2 | 2940746 6350253 | 2484 | 0.512 | 0.5666 | Yes | ||
67 | BCL2L1 | 1580452 4200152 5420484 | 2532 | 0.495 | 0.5671 | Yes | ||
68 | JMJD2B | 6350372 6400471 | 2625 | 0.464 | 0.5650 | No | ||
69 | PRIM2A | 7000692 | 2657 | 0.456 | 0.5661 | No | ||
70 | GTF2H1 | 2570746 2650148 | 2751 | 0.423 | 0.5636 | No | ||
71 | SMARCA5 | 6620050 | 2774 | 0.416 | 0.5650 | No | ||
72 | FBXL3 | 5910142 | 2852 | 0.387 | 0.5632 | No | ||
73 | MRPL15 | 360390 | 2896 | 0.375 | 0.5632 | No | ||
74 | ARFGEF2 | 5550500 | 2985 | 0.346 | 0.5605 | No | ||
75 | USP8 | 2640347 3840451 6100672 | 2993 | 0.344 | 0.5622 | No | ||
76 | PSMB1 | 2940402 | 3086 | 0.317 | 0.5592 | No | ||
77 | CORO1C | 4570397 | 3248 | 0.278 | 0.5522 | No | ||
78 | PPP1CC | 6380300 2510647 | 3376 | 0.251 | 0.5468 | No | ||
79 | FNDC3A | 2690097 3290044 | 3438 | 0.236 | 0.5449 | No | ||
80 | PAFAH2 | 3140451 5720593 6510014 | 3440 | 0.235 | 0.5463 | No | ||
81 | USP12 | 6130735 6620280 | 3514 | 0.221 | 0.5437 | No | ||
82 | RAB6A | 3840463 4780731 | 3585 | 0.206 | 0.5412 | No | ||
83 | YWHAE | 5310435 | 3768 | 0.178 | 0.5324 | No | ||
84 | CDC5L | 3130446 3390025 6400204 | 3771 | 0.177 | 0.5334 | No | ||
85 | GOPC | 6620400 | 3841 | 0.168 | 0.5307 | No | ||
86 | WEE1 | 3390070 | 3884 | 0.160 | 0.5294 | No | ||
87 | SSFA2 | 3870133 | 4070 | 0.139 | 0.5202 | No | ||
88 | PSMC2 | 7040010 | 4109 | 0.135 | 0.5190 | No | ||
89 | CYHR1 | 940609 2810463 3190332 3290692 4280411 | 4169 | 0.130 | 0.5166 | No | ||
90 | CDC25C | 2570673 4760161 6520707 | 4241 | 0.124 | 0.5135 | No | ||
91 | ATF1 | 4570142 5550095 | 4258 | 0.123 | 0.5133 | No | ||
92 | CSNK2A1 | 1580577 | 4329 | 0.116 | 0.5103 | No | ||
93 | JMJD1C | 940575 2120025 | 4363 | 0.113 | 0.5092 | No | ||
94 | SFRS9 | 3800047 | 4373 | 0.112 | 0.5094 | No | ||
95 | PTPRK | 1450433 2640142 | 4760 | 0.085 | 0.4889 | No | ||
96 | RAD23B | 2190671 | 4822 | 0.082 | 0.4861 | No | ||
97 | TRIM24 | 7050670 | 4846 | 0.080 | 0.4854 | No | ||
98 | RBM27 | 4050603 | 5142 | 0.067 | 0.4698 | No | ||
99 | CDC23 | 3190593 | 5157 | 0.066 | 0.4694 | No | ||
100 | TRIP4 | 630072 | 5208 | 0.064 | 0.4671 | No | ||
101 | PRKD3 | 5220520 5890519 | 5270 | 0.061 | 0.4642 | No | ||
102 | NBN | 730538 2470619 4780594 | 5294 | 0.060 | 0.4633 | No | ||
103 | TCERG1 | 2350551 4540397 5220746 | 5343 | 0.059 | 0.4610 | No | ||
104 | SAMD4A | 1170717 | 5809 | 0.042 | 0.4360 | No | ||
105 | MTIF2 | 2260270 | 5968 | 0.038 | 0.4277 | No | ||
106 | MYC | 380541 4670170 | 6382 | 0.028 | 0.4055 | No | ||
107 | CRK | 1230162 4780128 | 6649 | 0.022 | 0.3911 | No | ||
108 | GGPS1 | 840128 2320215 | 6655 | 0.022 | 0.3910 | No | ||
109 | SPRY2 | 5860184 | 6772 | 0.019 | 0.3848 | No | ||
110 | PLAG1 | 1450142 3870139 6520039 | 6905 | 0.017 | 0.3778 | No | ||
111 | TDG | 2900358 2940079 | 6908 | 0.017 | 0.3778 | No | ||
112 | MAPKAPK5 | 2510601 | 7024 | 0.015 | 0.3716 | No | ||
113 | VEGFC | 5910494 | 7045 | 0.014 | 0.3706 | No | ||
114 | GDI2 | 2370068 | 7070 | 0.014 | 0.3694 | No | ||
115 | NCOA6 | 1780333 6450110 | 7155 | 0.012 | 0.3649 | No | ||
116 | NMI | 520270 | 7171 | 0.012 | 0.3642 | No | ||
117 | FBXL7 | 6620711 | 7254 | 0.010 | 0.3598 | No | ||
118 | ATG5 | 6200433 5360324 | 7584 | 0.005 | 0.3420 | No | ||
119 | CFLAR | 2320605 6180440 | 8009 | -0.002 | 0.3190 | No | ||
120 | BUB1 | 5390270 | 8457 | -0.009 | 0.2947 | No | ||
121 | MFAP1 | 6660092 | 8806 | -0.015 | 0.2759 | No | ||
122 | XRCC5 | 7100286 | 8895 | -0.016 | 0.2713 | No | ||
123 | FZD1 | 3140215 | 9077 | -0.020 | 0.2616 | No | ||
124 | ACSL3 | 3140195 | 9151 | -0.021 | 0.2577 | No | ||
125 | KIF11 | 5390139 | 9371 | -0.025 | 0.2460 | No | ||
126 | EPS8 | 7050204 | 9559 | -0.028 | 0.2360 | No | ||
127 | FOSL1 | 430021 | 9630 | -0.029 | 0.2324 | No | ||
128 | CRSP6 | 2940358 | 9663 | -0.029 | 0.2308 | No | ||
129 | CDC42BPA | 840671 | 9751 | -0.031 | 0.2263 | No | ||
130 | OSBP | 5390471 | 10047 | -0.037 | 0.2105 | No | ||
131 | ARHGEF2 | 3360577 | 10092 | -0.038 | 0.2084 | No | ||
132 | JAG1 | 3440390 | 10141 | -0.039 | 0.2060 | No | ||
133 | RAB5A | 6520324 | 10144 | -0.039 | 0.2061 | No | ||
134 | CXXC5 | 840010 | 10210 | -0.040 | 0.2028 | No | ||
135 | IPO7 | 2190746 | 10270 | -0.041 | 0.1999 | No | ||
136 | UBN1 | 5900195 | 10688 | -0.051 | 0.1776 | No | ||
137 | NPAS2 | 770670 | 10825 | -0.054 | 0.1705 | No | ||
138 | CDK7 | 2640451 | 10877 | -0.056 | 0.1681 | No | ||
139 | CDH11 | 1230133 2100180 4610110 | 11003 | -0.059 | 0.1617 | No | ||
140 | BIRC6 | 70148 | 11038 | -0.060 | 0.1602 | No | ||
141 | TIAM2 | 360195 | 11492 | -0.072 | 0.1360 | No | ||
142 | HSPA1L | 4010538 | 11494 | -0.073 | 0.1364 | No | ||
143 | EIF4B | 5390563 5270577 | 11766 | -0.082 | 0.1222 | No | ||
144 | MRPS35 | 2370603 4070551 | 11833 | -0.084 | 0.1192 | No | ||
145 | RNF14 | 50402 1340041 6370687 | 11898 | -0.087 | 0.1162 | No | ||
146 | HS3ST3B1 | 380040 | 12146 | -0.096 | 0.1034 | No | ||
147 | MAP3K4 | 5720041 | 12231 | -0.100 | 0.0995 | No | ||
148 | NUFIP1 | 6350241 | 12273 | -0.102 | 0.0979 | No | ||
149 | CTGF | 4540577 | 12887 | -0.135 | 0.0654 | No | ||
150 | B4GALT5 | 1230692 | 12944 | -0.138 | 0.0632 | No | ||
151 | PLK1 | 1780369 2640121 | 13227 | -0.159 | 0.0489 | No | ||
152 | MCM3 | 5570068 | 13403 | -0.172 | 0.0404 | No | ||
153 | UBE2C | 6130017 | 13412 | -0.173 | 0.0411 | No | ||
154 | MTMR4 | 4540524 | 13560 | -0.186 | 0.0342 | No | ||
155 | ANLN | 1780113 2470537 6840047 | 13567 | -0.187 | 0.0351 | No | ||
156 | HSPA8 | 2120315 1050132 6550746 | 13775 | -0.208 | 0.0251 | No | ||
157 | THRAP3 | 6180309 | 13863 | -0.216 | 0.0217 | No | ||
158 | PKN2 | 940746 2350168 | 13997 | -0.232 | 0.0159 | No | ||
159 | RCC1 | 2480358 | 14128 | -0.246 | 0.0104 | No | ||
160 | ARPC5L | 1090148 | 14131 | -0.246 | 0.0118 | No | ||
161 | LUZP1 | 940075 4280458 6180070 | 14179 | -0.253 | 0.0108 | No | ||
162 | PSMA5 | 5390537 | 14212 | -0.258 | 0.0106 | No | ||
163 | FYN | 2100468 4760520 4850687 | 14227 | -0.260 | 0.0115 | No | ||
164 | ADSL | 5570484 | 14229 | -0.261 | 0.0130 | No | ||
165 | EGFR | 4920138 6480521 | 14360 | -0.276 | 0.0076 | No | ||
166 | MRPL1 | 430626 3130129 5220152 | 14393 | -0.280 | 0.0076 | No | ||
167 | PHF6 | 3120632 3990041 | 14457 | -0.291 | 0.0060 | No | ||
168 | EIF3S10 | 1190079 3840176 | 15047 | -0.403 | -0.0235 | No | ||
169 | CLCN7 | 2970095 | 15065 | -0.407 | -0.0219 | No | ||
170 | EPS15 | 4200215 | 15079 | -0.410 | -0.0201 | No | ||
171 | PDGFB | 3060440 6370008 | 15107 | -0.414 | -0.0190 | No | ||
172 | BUB3 | 3170546 | 15220 | -0.440 | -0.0224 | No | ||
173 | BLZF1 | 630088 | 15405 | -0.491 | -0.0294 | No | ||
174 | DLG5 | 450215 | 15777 | -0.620 | -0.0457 | No | ||
175 | ZDHHC16 | 4230390 | 16170 | -0.783 | -0.0622 | No | ||
176 | ARFGAP1 | 4780364 5390358 | 16223 | -0.808 | -0.0601 | No | ||
177 | DNAJA2 | 2630253 6860358 | 16239 | -0.817 | -0.0559 | No | ||
178 | USP3 | 2060332 | 16345 | -0.870 | -0.0562 | No | ||
179 | MID1IP1 | 2570739 | 16440 | -0.910 | -0.0557 | No | ||
180 | TARDBP | 870390 2350093 | 16452 | -0.917 | -0.0507 | No | ||
181 | SON | 3120148 5860239 7040403 | 16514 | -0.945 | -0.0482 | No | ||
182 | TOP1 | 770471 4060632 6650324 | 16558 | -0.968 | -0.0446 | No | ||
183 | FAF1 | 2450717 2510121 4730156 | 16649 | -1.002 | -0.0433 | No | ||
184 | SIRPA | 130465 5700332 | 16718 | -1.028 | -0.0407 | No | ||
185 | PANX1 | 6550632 | 16755 | -1.045 | -0.0362 | No | ||
186 | SNIP1 | 5360092 | 17577 | -1.585 | -0.0711 | No | ||
187 | BAG2 | 2900324 | 17691 | -1.693 | -0.0668 | No | ||
188 | RBM14 | 5340731 5690315 | 17794 | -1.791 | -0.0614 | No | ||
189 | HIST1H4C | 5570528 | 17895 | -1.886 | -0.0552 | No | ||
190 | SLC2A1 | 2100609 | 17911 | -1.907 | -0.0443 | No | ||
191 | HIST1H4B | 4210524 | 17981 | -1.982 | -0.0359 | No | ||
192 | HSPE1 | 3170438 | 18090 | -2.106 | -0.0288 | No | ||
193 | LHFPL2 | 450020 | 18245 | -2.327 | -0.0229 | No | ||
194 | KIAA0859 | 510497 770722 1340687 6840711 | 18320 | -2.453 | -0.0118 | No | ||
195 | WNT5B | 5080162 | 18606 | -4.536 | 0.0005 | No |