DatasetSet_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls
#wtNotch_versus_truncNotch.phenotype_truncNotch_versus_wtNotch.cls
#wtNotch_versus_truncNotch_repos
Phenotypephenotype_truncNotch_versus_wtNotch.cls#wtNotch_versus_truncNotch_repos
Upregulated in classwtNotch
GeneSetET743_SARCOMA_48HRS_DN
Enrichment Score (ES)0.5673441
Normalized Enrichment Score (NES)1.7555209
Nominal p-value0.0
FDR q-value0.048040852
FWER p-Value0.394
Table: GSEA Results Summary



Fig 1: Enrichment plot: ET743_SARCOMA_48HRS_DN   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEDESCRIPTION
(from dataset)
GENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1SLC4A1AP3190576143.8660.0293Yes
2LBR4540671263.5820.0565Yes
3CCT46380161713.0520.0779Yes
4OGT2360131 46103331092.8290.0978Yes
5PSMD1456905931192.8060.1192Yes
6RAB1A23706711402.7270.1393Yes
7RABGGTB31200371522.6780.1595Yes
8DDX2032903481622.6490.1796Yes
9PSMA445604271982.5390.1974Yes
10RPP1470400142342.4700.2147Yes
11CCNH31903473092.2890.2285Yes
12RIPK131900253252.2640.2453Yes
13PRKACB42101703392.2350.2620Yes
14TBK156903383482.2220.2788Yes
15SLC25A1721003693702.1890.2947Yes
16HDAC240504333722.1880.3116Yes
17FNTA700594092.1200.3262Yes
18DDX2161004464422.0730.3405Yes
19GTF2H251303584452.0690.3565Yes
20PJA24305374702.0370.3710Yes
21PCNA9407545261.9410.3832Yes
22MAP3K760400685341.9290.3978Yes
23UBE2D331904525421.9150.4123Yes
24POLD364002785531.8990.4265Yes
25RAP1B37101385991.8610.4385Yes
26TNFSF5IP120600956041.8580.4527Yes
27MCTS161301336361.8210.4652Yes
28OSBPL925703737281.7150.4736Yes
29ELOVL653407468161.6330.4816Yes
30TOP2A3607179091.5310.4885Yes
31XBP138405949391.4910.4985Yes
32TMPO40504949431.4890.5100Yes
33GTF2B686068511051.3280.5116Yes
34RBM1787059211681.2650.5180Yes
35HSPH1169001711691.2650.5279Yes
36SIRT1119073112451.2010.5332Yes
37SUPV3L1117007212871.1650.5400Yes
38MAPK14529073113011.1500.5482Yes
39UBE2D24590671 651044613631.1020.5535Yes
40TXNRD1659044613711.0980.5616Yes
41MAT2A4070026 4730079 602028015550.9950.5595Yes
42EML4570037316510.9410.5616Yes
43STK17B13009117570.8740.5627Yes
44BIRC22940435 473002019530.7570.5581Yes
45CRLF3662001920670.6850.5573Yes
46CCNA2529007521760.6340.5564Yes
47ZDHHC5169071122570.5980.5567Yes
48RCOR1536071722850.5870.5598Yes
49PSMC6281002123560.5600.5603Yes
50ERCC3690000823820.5510.5633Yes
51GABPB26130450 705073524160.5380.5657Yes
52PSME3281053724750.5150.5665Yes
53BCL2L11580452 4200152 542048425320.4950.5673Yes
54PRIM2A700069226570.4560.5642No
55GTF2H12570746 265014827510.4230.5624No
56SMARCA5662005027740.4160.5645No
57FBXL3591014228520.3870.5633No
58MRPL1536039028960.3750.5639No
59PSMB1294040230860.3170.5561No
60PPP1CC6380300 251064733760.2510.5424No
61FNDC3A2690097 329004434380.2360.5410No
62PAFAH23140451 5720593 651001434400.2350.5427No
63USP126130735 662028035140.2210.5405No
64CDC5L3130446 3390025 640020437710.1770.5280No
65GOPC662040038410.1680.5256No
66SSFA2387013340700.1390.5143No
67PSMC2704001041090.1350.5133No
68CYHR1940609 2810463 3190332 3290692 428041141690.1300.5111No
69ATF14570142 555009542580.1230.5073No
70CSNK2A1158057743290.1160.5044No
71JMJD1C940575 212002543630.1130.5035No
72SFRS9380004743730.1120.5039No
73RBM27405060351420.0670.4629No
74CDC23319059351570.0660.4626No
75TRIP463007252080.0640.4604No
76NBN730538 2470619 478059452940.0600.4563No
77TCERG12350551 4540397 522074653430.0590.4541No
78MTIF2226027059680.0380.4207No
79PLAG11450142 3870139 652003969050.0170.3701No
80TDG2900358 294007969080.0170.3702No
81MAPKAPK5251060170240.0150.3640No
82VEGFC591049470450.0140.3631No
83NCOA61780333 645011071550.0120.3573No
84NMI52027071710.0120.3565No
85FBXL7662071172540.0100.3522No
86ATG56200433 536032475840.0050.3344No
87CFLAR2320605 61804408009-0.0020.3115No
88BUB153902708457-0.0090.2874No
89MFAP166600928806-0.0150.2686No
90FZD131402159077-0.0200.2542No
91KIF1153901399371-0.0250.2385No
92EPS870502049559-0.0280.2286No
93FOSL14300219630-0.0290.2250No
94CRSP629403589663-0.0290.2235No
95CDC42BPA8406719751-0.0310.2191No
96RAB5A652032410144-0.0390.1981No
97CXXC584001010210-0.0400.1949No
98IPO7219074610270-0.0410.1921No
99UBN1590019510688-0.0510.1699No
100CDK7264045110877-0.0560.1602No
101CDH111230133 2100180 461011011003-0.0590.1538No
102BIRC67014811038-0.0600.1525No
103TIAM236019511492-0.0720.1285No
104HSPA1L401053811494-0.0730.1290No
105RNF1450402 1340041 637068711898-0.0870.1079No
106HS3ST3B138004012146-0.0960.0953No
107NUFIP1635024112273-0.1020.0892No
108CTGF454057712887-0.1350.0571No
109B4GALT5123069212944-0.1380.0551No
110PLK11780369 264012113227-0.1590.0411No
111MCM3557006813403-0.1720.0330No
112UBE2C613001713412-0.1730.0339No
113MTMR4454052413560-0.1860.0274No
114HSPA82120315 1050132 655074613775-0.2080.0174No
115THRAP3618030913863-0.2160.0144No
116PSMA5539053714212-0.258-0.0024No
117ADSL557048414229-0.261-0.0013No
118MRPL1430626 3130129 522015214393-0.280-0.0079No
119EIF3S101190079 384017615047-0.403-0.0401No
120CLCN7297009515065-0.407-0.0379No
121PDGFB3060440 637000815107-0.414-0.0369No
122BUB3317054615220-0.440-0.0395No
123BLZF163008815405-0.491-0.0457No
124DLG545021515777-0.620-0.0609No
125ZDHHC16423039016170-0.783-0.0761No
126ARFGAP14780364 539035816223-0.808-0.0726No
127DNAJA22630253 686035816239-0.817-0.0671No
128USP3206033216345-0.870-0.0660No
129MID1IP1257073916440-0.910-0.0640No
130TARDBP870390 235009316452-0.917-0.0575No
131SON3120148 5860239 704040316514-0.945-0.0534No
132TOP1770471 4060632 665032416558-0.968-0.0482No
133SIRPA130465 570033216718-1.028-0.0489No
134PANX1655063216755-1.045-0.0427No
135SNIP1536009217577-1.585-0.0748No
136BAG2290032417691-1.693-0.0678No
137RBM145340731 569031517794-1.791-0.0594No
138SLC2A1210060917911-1.907-0.0508No
139HSPE1317043818090-2.106-0.0441No
140LHFPL245002018245-2.327-0.0343No
141KIAA0859510497 770722 1340687 684071118320-2.453-0.0193No
142WNT5B508016218606-4.5360.0005No
Table: GSEA details [plain text format]



Fig 2: ET743_SARCOMA_48HRS_DN   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: ET743_SARCOMA_48HRS_DN: Random ES distribution   
Gene set null distribution of ES for ET743_SARCOMA_48HRS_DN