Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls #wtNotch_versus_truncNotch.phenotype_truncNotch_versus_wtNotch.cls #wtNotch_versus_truncNotch_repos |
| Phenotype | phenotype_truncNotch_versus_wtNotch.cls#wtNotch_versus_truncNotch_repos |
| Upregulated in class | truncNotch |
| GeneSet | CROONQUIST_IL6_STROMA_UP |
| Enrichment Score (ES) | -0.7015291 |
| Normalized Enrichment Score (NES) | -1.616722 |
| Nominal p-value | 0.00990099 |
| FDR q-value | 0.15757075 |
| FWER p-Value | 0.952 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | SLC25A4 | 2360519 | 2158 | 0.642 | -0.0901 | No | ||
| 2 | COL6A1 | 1410670 2940091 6510086 | 2461 | 0.518 | -0.0854 | No | ||
| 3 | SULF1 | 430575 | 4492 | 0.103 | -0.1904 | No | ||
| 4 | ACTA2 | 60008 1230082 | 4520 | 0.100 | -0.1878 | No | ||
| 5 | SPARC | 1690086 | 4765 | 0.085 | -0.1975 | No | ||
| 6 | IL6 | 380133 | 5299 | 0.060 | -0.2237 | No | ||
| 7 | FOSB | 1940142 | 5598 | 0.049 | -0.2378 | No | ||
| 8 | IGFBP3 | 2370500 | 5737 | 0.044 | -0.2434 | No | ||
| 9 | RGS2 | 1090736 | 7777 | 0.002 | -0.3531 | No | ||
| 10 | TMSB4X | 6620114 | 8778 | -0.014 | -0.4063 | No | ||
| 11 | LOX | 5340372 | 9017 | -0.019 | -0.4183 | No | ||
| 12 | THBS2 | 2850136 | 12809 | -0.130 | -0.6171 | No | ||
| 13 | CTGF | 4540577 | 12887 | -0.135 | -0.6157 | No | ||
| 14 | CCL3 | 2810092 | 13593 | -0.190 | -0.6460 | No | ||
| 15 | NNMT | 450471 | 13621 | -0.192 | -0.6397 | No | ||
| 16 | CXCL2 | 610398 | 13750 | -0.205 | -0.6382 | No | ||
| 17 | SERPINE1 | 4210403 | 13918 | -0.222 | -0.6382 | No | ||
| 18 | COL1A2 | 380364 | 14606 | -0.319 | -0.6623 | No | ||
| 19 | COL6A3 | 2640717 4070064 5390717 | 14929 | -0.376 | -0.6644 | Yes | ||
| 20 | FOS | 1850315 | 14971 | -0.386 | -0.6509 | Yes | ||
| 21 | NR4A2 | 60273 | 15192 | -0.433 | -0.6452 | Yes | ||
| 22 | TPM2 | 520735 3870390 | 15310 | -0.461 | -0.6328 | Yes | ||
| 23 | IGFBP7 | 520411 3060110 5290152 | 16588 | -0.984 | -0.6616 | Yes | ||
| 24 | IER3 | 5860021 | 16602 | -0.990 | -0.6222 | Yes | ||
| 25 | NOTCH3 | 3060603 | 16697 | -1.020 | -0.5859 | Yes | ||
| 26 | NFKBIA | 1570152 | 16859 | -1.101 | -0.5499 | Yes | ||
| 27 | CCL4 | 50368 430047 | 17242 | -1.353 | -0.5156 | Yes | ||
| 28 | LOXL1 | 3520537 | 17566 | -1.577 | -0.4691 | Yes | ||
| 29 | FSCN1 | 3450463 | 17928 | -1.922 | -0.4106 | Yes | ||
| 30 | TGM2 | 5360452 | 18113 | -2.131 | -0.3341 | Yes | ||
| 31 | LAMA4 | 3170647 | 18310 | -2.437 | -0.2459 | Yes | ||
| 32 | TGFBI | 2060446 6900112 | 18425 | -2.742 | -0.1409 | Yes | ||
| 33 | DUSP1 | 6860121 | 18587 | -3.727 | 0.0016 | Yes |
