Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls #wtNotch_versus_truncNotch.phenotype_truncNotch_versus_wtNotch.cls #wtNotch_versus_truncNotch_repos |
| Phenotype | phenotype_truncNotch_versus_wtNotch.cls#wtNotch_versus_truncNotch_repos |
| Upregulated in class | truncNotch |
| GeneSet | BASSO_GERMINAL_CENTER_CD40_UP |
| Enrichment Score (ES) | -0.60716534 |
| Normalized Enrichment Score (NES) | -1.6215324 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.15479161 |
| FWER p-Value | 0.944 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | TNFAIP8 | 2760551 | 504 | 1.986 | 0.0034 | No | ||
| 2 | HSP90B1 | 5670576 | 785 | 1.665 | 0.0140 | No | ||
| 3 | CHD1 | 4590048 | 880 | 1.565 | 0.0331 | No | ||
| 4 | ICAM1 | 6980138 | 1452 | 1.039 | 0.0183 | No | ||
| 5 | RAB27A | 450019 | 2094 | 0.673 | -0.0059 | No | ||
| 6 | TNF | 6650603 | 2136 | 0.652 | 0.0020 | No | ||
| 7 | LGALS1 | 6450193 | 2220 | 0.613 | 0.0070 | No | ||
| 8 | STAT1 | 6510204 6590553 | 2575 | 0.480 | -0.0047 | No | ||
| 9 | TCEB3 | 5890156 | 2914 | 0.368 | -0.0173 | No | ||
| 10 | KCNN4 | 2680129 | 2973 | 0.349 | -0.0150 | No | ||
| 11 | DTX2 | 4210041 7000008 | 3104 | 0.312 | -0.0172 | No | ||
| 12 | IL1B | 2640364 | 3207 | 0.286 | -0.0183 | No | ||
| 13 | BLR1 | 1500300 5420017 | 3341 | 0.256 | -0.0215 | No | ||
| 14 | DUSP2 | 2370184 | 3442 | 0.235 | -0.0233 | No | ||
| 15 | SLAMF1 | 580131 4920110 | 3807 | 0.173 | -0.0403 | No | ||
| 16 | RXRA | 3800471 | 4053 | 0.141 | -0.0513 | No | ||
| 17 | LYN | 6040600 | 5608 | 0.048 | -0.1344 | No | ||
| 18 | PHACTR1 | 3190176 5670286 | 6418 | 0.027 | -0.1777 | No | ||
| 19 | CCL22 | 6380086 | 7347 | 0.009 | -0.2276 | No | ||
| 20 | ZFP36L1 | 2510138 4120048 | 7959 | -0.001 | -0.2605 | No | ||
| 21 | CFLAR | 2320605 6180440 | 8009 | -0.002 | -0.2631 | No | ||
| 22 | ELL2 | 6420091 | 8041 | -0.002 | -0.2648 | No | ||
| 23 | IRF4 | 610133 | 8348 | -0.007 | -0.2812 | No | ||
| 24 | TRAF1 | 3440735 | 8773 | -0.014 | -0.3038 | No | ||
| 25 | TMSB4X | 6620114 | 8778 | -0.014 | -0.3038 | No | ||
| 26 | MYB | 1660494 5860451 6130706 | 8845 | -0.015 | -0.3071 | No | ||
| 27 | NCF2 | 540129 2370441 2650133 | 8928 | -0.017 | -0.3113 | No | ||
| 28 | PLEK | 1090039 | 9750 | -0.031 | -0.3551 | No | ||
| 29 | ARHGEF2 | 3360577 | 10092 | -0.038 | -0.3729 | No | ||
| 30 | PLXNC1 | 5860315 | 10179 | -0.040 | -0.3770 | No | ||
| 31 | SNF1LK | 6110403 | 10563 | -0.048 | -0.3969 | No | ||
| 32 | MEF2C | 670025 780338 | 11302 | -0.067 | -0.4357 | No | ||
| 33 | MAP3K8 | 2940286 | 11413 | -0.070 | -0.4405 | No | ||
| 34 | LTA | 1740088 | 11847 | -0.085 | -0.4626 | No | ||
| 35 | TNFSF9 | 1190408 | 11950 | -0.089 | -0.4667 | No | ||
| 36 | CD40 | 2760471 2940390 6220402 6220452 | 12258 | -0.101 | -0.4817 | No | ||
| 37 | TCFL5 | 2190019 | 12436 | -0.110 | -0.4896 | No | ||
| 38 | CD44 | 3990072 4850671 5860411 6860148 7050551 | 12759 | -0.127 | -0.5050 | No | ||
| 39 | ARID5B | 110403 | 13120 | -0.151 | -0.5221 | No | ||
| 40 | ICOSLG | 70128 | 13471 | -0.178 | -0.5382 | No | ||
| 41 | MTMR4 | 4540524 | 13560 | -0.186 | -0.5401 | No | ||
| 42 | RGS1 | 4060347 4540181 | 13580 | -0.188 | -0.5382 | No | ||
| 43 | CCL3 | 2810092 | 13593 | -0.190 | -0.5359 | No | ||
| 44 | CR2 | 2850332 6450397 | 13719 | -0.202 | -0.5396 | No | ||
| 45 | SH2B3 | 4810451 4850128 | 14088 | -0.240 | -0.5557 | No | ||
| 46 | HTR3A | 3310180 | 14187 | -0.254 | -0.5571 | No | ||
| 47 | TNFAIP2 | 70438 1740215 | 14821 | -0.354 | -0.5858 | No | ||
| 48 | DDIT4 | 2570408 | 15052 | -0.404 | -0.5919 | No | ||
| 49 | TNFAIP3 | 2900142 | 15056 | -0.405 | -0.5859 | No | ||
| 50 | JUNB | 4230048 | 15452 | -0.504 | -0.5994 | Yes | ||
| 51 | ADAM8 | 450347 5670609 | 15539 | -0.535 | -0.5958 | Yes | ||
| 52 | BCL2 | 730132 1570736 2470138 3800044 4810037 5690068 5860504 6650164 | 15654 | -0.579 | -0.5930 | Yes | ||
| 53 | TMC6 | 60736 1230093 2100288 4850735 | 15694 | -0.592 | -0.5860 | Yes | ||
| 54 | TRIP10 | 460438 | 15706 | -0.596 | -0.5774 | Yes | ||
| 55 | LAPTM5 | 5550372 | 15782 | -0.622 | -0.5718 | Yes | ||
| 56 | ISGF3G | 3190131 7100142 | 15967 | -0.696 | -0.5710 | Yes | ||
| 57 | CD83 | 4150242 | 16053 | -0.739 | -0.5642 | Yes | ||
| 58 | GADD45B | 2350408 | 16116 | -0.766 | -0.5557 | Yes | ||
| 59 | STAT5A | 2680458 | 16269 | -0.833 | -0.5511 | Yes | ||
| 60 | LITAF | 6940671 | 16484 | -0.932 | -0.5482 | Yes | ||
| 61 | IER3 | 5860021 | 16602 | -0.990 | -0.5393 | Yes | ||
| 62 | STK10 | 2760010 3940605 | 16619 | -0.995 | -0.5248 | Yes | ||
| 63 | NFKB2 | 2320670 | 16799 | -1.069 | -0.5179 | Yes | ||
| 64 | CAPG | 770373 | 16823 | -1.079 | -0.5025 | Yes | ||
| 65 | NFKBIA | 1570152 | 16859 | -1.101 | -0.4874 | Yes | ||
| 66 | EHD1 | 3840731 | 16873 | -1.117 | -0.4709 | Yes | ||
| 67 | IRF5 | 3360519 | 17010 | -1.203 | -0.4597 | Yes | ||
| 68 | CCL4 | 50368 430047 | 17242 | -1.353 | -0.4512 | Yes | ||
| 69 | PTP4A3 | 3780504 6400364 | 17269 | -1.371 | -0.4315 | Yes | ||
| 70 | EBI2 | 6220722 | 17290 | -1.383 | -0.4112 | Yes | ||
| 71 | CCR7 | 2060687 | 17540 | -1.557 | -0.4007 | Yes | ||
| 72 | SYNGR2 | 4050332 4560091 6130348 | 17573 | -1.585 | -0.3779 | Yes | ||
| 73 | IFI30 | 730309 2940500 | 17761 | -1.748 | -0.3611 | Yes | ||
| 74 | RAC2 | 1580541 | 17878 | -1.867 | -0.3385 | Yes | ||
| 75 | UNC119 | 360372 | 17959 | -1.963 | -0.3125 | Yes | ||
| 76 | TAP1 | 4050047 | 18244 | -2.324 | -0.2920 | Yes | ||
| 77 | LHFPL2 | 450020 | 18245 | -2.327 | -0.2561 | Yes | ||
| 78 | PIK3CD | 3060546 | 18276 | -2.382 | -0.2210 | Yes | ||
| 79 | PTK2B | 4730411 | 18576 | -3.507 | -0.1830 | Yes | ||
| 80 | MAPKAPK2 | 2850500 | 18590 | -3.846 | -0.1243 | Yes | ||
| 81 | NFKBIE | 580390 2190086 | 18594 | -4.000 | -0.0628 | Yes | ||
| 82 | BATF | 6760390 | 18597 | -4.143 | 0.0010 | Yes |
