Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls #wtNotch_versus_truncNotch.phenotype_truncNotch_versus_wtNotch.cls #wtNotch_versus_truncNotch_repos |
| Phenotype | phenotype_truncNotch_versus_wtNotch.cls#wtNotch_versus_truncNotch_repos |
| Upregulated in class | truncNotch |
| GeneSet | REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA__ |
| Enrichment Score (ES) | -0.6500763 |
| Normalized Enrichment Score (NES) | -1.5808561 |
| Nominal p-value | 0.0032102729 |
| FDR q-value | 0.32555264 |
| FWER p-Value | 0.924 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | LAMP2 | 1230402 1980373 | 984 | 1.449 | 0.0096 | No | ||
| 2 | FN1 | 1170601 2970647 6220288 6940037 | 2465 | 0.517 | -0.0477 | No | ||
| 3 | EGF | 5220154 | 2474 | 0.515 | -0.0259 | No | ||
| 4 | SERPINF2 | 2470390 2690292 | 3147 | 0.299 | -0.0492 | No | ||
| 5 | FGG | 4610717 | 4467 | 0.104 | -0.1157 | No | ||
| 6 | SPARC | 1690086 | 4765 | 0.085 | -0.1280 | No | ||
| 7 | HGF | 3360593 | 4957 | 0.075 | -0.1351 | No | ||
| 8 | THBS1 | 4560494 430288 | 5939 | 0.039 | -0.1862 | No | ||
| 9 | FGB | 7000010 | 6157 | 0.033 | -0.1965 | No | ||
| 10 | VWF | 4670519 | 6359 | 0.028 | -0.2061 | No | ||
| 11 | LEFTY2 | 5670364 | 6922 | 0.017 | -0.2356 | No | ||
| 12 | HRG | 2340161 | 7074 | 0.014 | -0.2432 | No | ||
| 13 | PROS1 | 5420465 | 7172 | 0.012 | -0.2479 | No | ||
| 14 | GP5 | 2510088 | 7336 | 0.009 | -0.2563 | No | ||
| 15 | CD36 | 5890575 | 7533 | 0.006 | -0.2666 | No | ||
| 16 | A2M | 6620039 | 7900 | -0.000 | -0.2863 | No | ||
| 17 | ITGA2B | 2680538 | 8507 | -0.010 | -0.3185 | No | ||
| 18 | TMSB4X | 6620114 | 8778 | -0.014 | -0.3324 | No | ||
| 19 | STXBP3 | 780706 | 9566 | -0.028 | -0.3735 | No | ||
| 20 | F8 | 2190647 2340465 | 9575 | -0.028 | -0.3728 | No | ||
| 21 | GP1BB | 3780075 | 10194 | -0.040 | -0.4043 | No | ||
| 22 | GP1BA | 6590372 | 10453 | -0.046 | -0.4163 | No | ||
| 23 | PLG | 3360270 3840100 | 10781 | -0.053 | -0.4316 | No | ||
| 24 | GP9 | 1190181 | 11185 | -0.063 | -0.4505 | No | ||
| 25 | F5 | 1990619 | 11694 | -0.079 | -0.4745 | No | ||
| 26 | KNG1 | 6400576 6770347 | 12586 | -0.118 | -0.5173 | No | ||
| 27 | CFD | 2320736 | 12965 | -0.140 | -0.5316 | No | ||
| 28 | PPBP | 5130446 | 13605 | -0.191 | -0.5578 | No | ||
| 29 | ITGB3 | 5270463 | 13680 | -0.198 | -0.5533 | No | ||
| 30 | MMRN1 | 7050278 | 13721 | -0.202 | -0.5467 | No | ||
| 31 | FGA | 4210056 5220239 | 13810 | -0.211 | -0.5423 | No | ||
| 32 | SERPINE1 | 4210403 | 13918 | -0.222 | -0.5385 | No | ||
| 33 | SELP | 6040193 | 14063 | -0.237 | -0.5360 | No | ||
| 34 | APP | 2510053 | 14374 | -0.278 | -0.5407 | No | ||
| 35 | IGF1 | 1990193 3130377 3290280 | 14585 | -0.315 | -0.5384 | No | ||
| 36 | CD9 | 4730041 | 16660 | -1.005 | -0.6067 | Yes | ||
| 37 | PF4 | 6130332 | 16706 | -1.023 | -0.5649 | Yes | ||
| 38 | STX4 | 6270632 | 16780 | -1.060 | -0.5230 | Yes | ||
| 39 | TIMP1 | 1010326 | 17404 | -1.464 | -0.4934 | Yes | ||
| 40 | SERPING1 | 5550440 | 17774 | -1.761 | -0.4372 | Yes | ||
| 41 | CD63 | 6660451 | 17955 | -1.956 | -0.3624 | Yes | ||
| 42 | CLU | 5420075 | 18405 | -2.667 | -0.2714 | Yes | ||
| 43 | ALDOA | 6290672 | 18479 | -2.907 | -0.1498 | Yes | ||
| 44 | ACTN4 | 3840301 4590390 7050132 | 18583 | -3.637 | 0.0018 | Yes |
