Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_03_wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy_repos |
| Phenotype | phenotype_wtNotch_versus_normalThy.cls#wtNotch_versus_normalThy_repos |
| Upregulated in class | normalThy |
| GeneSet | PROTEIN_PROCESSING |
| Enrichment Score (ES) | -0.74199176 |
| Normalized Enrichment Score (NES) | -1.6337835 |
| Nominal p-value | 0.0037105752 |
| FDR q-value | 0.21730402 |
| FWER p-Value | 0.58 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | PSEN2 | 130382 | 2754 | 0.678 | -0.1258 | No | ||
| 2 | METAP2 | 1570441 4010026 4850204 | 3424 | 0.420 | -0.1478 | No | ||
| 3 | PTCH1 | 430278 | 3830 | 0.292 | -0.1600 | No | ||
| 4 | PPP2R5C | 3310121 6650672 | 3893 | 0.277 | -0.1541 | No | ||
| 5 | TNK1 | 4730279 | 5017 | 0.130 | -0.2102 | No | ||
| 6 | TTN | 2320161 4670056 6550026 | 5291 | 0.113 | -0.2212 | No | ||
| 7 | CUZD1 | 7100673 | 6329 | 0.067 | -0.2748 | No | ||
| 8 | MAP3K9 | 3290707 | 6885 | 0.050 | -0.3030 | No | ||
| 9 | AKT1 | 5290746 | 7808 | 0.031 | -0.3516 | No | ||
| 10 | MAP3K10 | 3360168 4850180 | 8267 | 0.023 | -0.3755 | No | ||
| 11 | PSEN1 | 130403 2030647 6100603 | 8356 | 0.021 | -0.3795 | No | ||
| 12 | APH1A | 4060273 4670465 6450711 | 8524 | 0.018 | -0.3879 | No | ||
| 13 | PCSK5 | 5720600 | 9429 | 0.004 | -0.4364 | No | ||
| 14 | MAP3K13 | 3190017 | 9942 | -0.003 | -0.4639 | No | ||
| 15 | CDKL5 | 2450070 | 10141 | -0.006 | -0.4743 | No | ||
| 16 | MYO3A | 5290494 | 10627 | -0.014 | -0.5000 | No | ||
| 17 | MAP3K12 | 2470373 6420162 | 10936 | -0.019 | -0.5159 | No | ||
| 18 | PCSK9 | 3120044 | 13088 | -0.069 | -0.6294 | No | ||
| 19 | PAK1 | 4540315 | 13219 | -0.075 | -0.6339 | No | ||
| 20 | ECE2 | 4070750 | 13363 | -0.081 | -0.6389 | No | ||
| 21 | SCG5 | 4390328 | 15279 | -0.334 | -0.7309 | Yes | ||
| 22 | FURIN | 4120168 | 15450 | -0.385 | -0.7273 | Yes | ||
| 23 | INSR | 1190504 | 15509 | -0.415 | -0.7167 | Yes | ||
| 24 | LMTK2 | 6650692 | 15701 | -0.498 | -0.7105 | Yes | ||
| 25 | MIPEP | 6370497 6400609 | 15995 | -0.649 | -0.7048 | Yes | ||
| 26 | UHMK1 | 3850670 6450064 | 16003 | -0.654 | -0.6835 | Yes | ||
| 27 | PAK2 | 360438 7050068 | 16123 | -0.727 | -0.6658 | Yes | ||
| 28 | EIF2AK1 | 2470301 | 16431 | -0.915 | -0.6520 | Yes | ||
| 29 | CRKRS | 510537 2510551 | 16752 | -1.127 | -0.6319 | Yes | ||
| 30 | CAMKK2 | 5270047 | 16998 | -1.342 | -0.6006 | Yes | ||
| 31 | IGF1R | 3360494 | 17121 | -1.500 | -0.5574 | Yes | ||
| 32 | NCSTN | 940601 6400594 | 17469 | -1.981 | -0.5105 | Yes | ||
| 33 | EIF2AK3 | 4280161 | 17796 | -2.616 | -0.4414 | Yes | ||
| 34 | STK4 | 2640152 | 17801 | -2.623 | -0.3547 | Yes | ||
| 35 | MAP3K11 | 7000039 | 17928 | -2.933 | -0.2643 | Yes | ||
| 36 | DYRK1A | 3190181 | 18295 | -4.333 | -0.1404 | Yes | ||
| 37 | MAP3K3 | 610685 | 18366 | -4.757 | 0.0135 | Yes |
