Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_03_wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy_repos |
| Phenotype | phenotype_wtNotch_versus_normalThy.cls#wtNotch_versus_normalThy_repos |
| Upregulated in class | normalThy |
| GeneSet | CALCIUM_ION_BINDING |
| Enrichment Score (ES) | -0.6288105 |
| Normalized Enrichment Score (NES) | -1.5582492 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.23948783 |
| FWER p-Value | 0.982 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | HSP90B1 | 5670576 | 755 | 2.427 | -0.0055 | No | ||
| 2 | TESC | 6550273 | 1423 | 1.602 | -0.0182 | No | ||
| 3 | LRP1 | 6270386 | 1571 | 1.465 | -0.0048 | No | ||
| 4 | CABP1 | 6350750 | 1671 | 1.376 | 0.0098 | No | ||
| 5 | RASGRP1 | 1050148 4050632 6510671 | 2118 | 1.023 | 0.0006 | No | ||
| 6 | FBN1 | 3170181 | 2217 | 0.990 | 0.0097 | No | ||
| 7 | S100A1 | 6770707 | 2433 | 0.861 | 0.0107 | No | ||
| 8 | PRSS2 | 1090286 | 2716 | 0.702 | 0.0057 | No | ||
| 9 | NOTCH4 | 2450040 6370707 | 3068 | 0.549 | -0.0053 | No | ||
| 10 | LTBP4 | 50164 1780301 | 3451 | 0.409 | -0.0200 | No | ||
| 11 | CAPN9 | 3450097 5910687 | 3595 | 0.358 | -0.0225 | No | ||
| 12 | CALML3 | 1980593 | 3696 | 0.324 | -0.0232 | No | ||
| 13 | CABP4 | 1660471 | 3820 | 0.293 | -0.0256 | No | ||
| 14 | SLC25A13 | 4920072 5690722 | 4250 | 0.211 | -0.0456 | No | ||
| 15 | GSN | 3830168 | 4342 | 0.200 | -0.0476 | No | ||
| 16 | ASPH | 360722 1940039 2100066 2340121 2650113 2810064 2970008 3140040 3800750 4210014 4280133 4590035 4760433 6370671 6940338 | 4595 | 0.169 | -0.0588 | No | ||
| 17 | THBS3 | 2360465 4050176 | 4655 | 0.162 | -0.0596 | No | ||
| 18 | GPD2 | 2350075 2690411 | 5021 | 0.130 | -0.0774 | No | ||
| 19 | CPNE6 | 6520338 | 5146 | 0.122 | -0.0823 | No | ||
| 20 | KCNIP3 | 6290050 | 5368 | 0.109 | -0.0927 | No | ||
| 21 | ANXA1 | 2320053 | 5526 | 0.100 | -0.0997 | No | ||
| 22 | ANXA10 | 4050750 | 5641 | 0.095 | -0.1044 | No | ||
| 23 | REPS2 | 2690066 | 5876 | 0.084 | -0.1159 | No | ||
| 24 | CABP2 | 840142 | 6064 | 0.076 | -0.1248 | No | ||
| 25 | MAN1C1 | 730133 870398 2340044 | 6066 | 0.076 | -0.1238 | No | ||
| 26 | GCA | 380148 2120576 1170670 3190301 | 6106 | 0.075 | -0.1248 | No | ||
| 27 | RCVRN | 4010279 | 6316 | 0.067 | -0.1351 | No | ||
| 28 | CALB1 | 460070 | 6444 | 0.062 | -0.1411 | No | ||
| 29 | PKD2 | 4670390 | 6489 | 0.061 | -0.1425 | No | ||
| 30 | SPARC | 1690086 | 6520 | 0.060 | -0.1433 | No | ||
| 31 | TPT1 | 3450035 | 6562 | 0.059 | -0.1446 | No | ||
| 32 | DUOX2 | 1410575 | 6933 | 0.049 | -0.1639 | No | ||
| 33 | PLEK | 1090039 | 7443 | 0.038 | -0.1908 | No | ||
| 34 | THBS4 | 3710348 | 7526 | 0.036 | -0.1947 | No | ||
| 35 | PDCD6 | 4760239 | 7713 | 0.033 | -0.2043 | No | ||
| 36 | DSPP | 5890403 | 7923 | 0.029 | -0.2151 | No | ||
| 37 | CALU | 2680403 3520056 4610348 5720176 6130121 | 8083 | 0.026 | -0.2233 | No | ||
| 38 | RCN1 | 2480041 | 8399 | 0.020 | -0.2400 | No | ||
| 39 | GPR98 | 6400647 | 8876 | 0.012 | -0.2655 | No | ||
| 40 | RCN2 | 840324 | 8895 | 0.012 | -0.2663 | No | ||
| 41 | FREQ | 3140039 4060600 4560670 | 9325 | 0.005 | -0.2894 | No | ||
| 42 | HPCAL1 | 1980129 2350348 | 9370 | 0.005 | -0.2917 | No | ||
| 43 | S100G | 2340064 | 9470 | 0.003 | -0.2970 | No | ||
| 44 | SPOCK2 | 6650369 | 9521 | 0.003 | -0.2996 | No | ||
| 45 | TGM3 | 840576 | 9594 | 0.001 | -0.3035 | No | ||
| 46 | MYL2 | 70471 | 9678 | 0.000 | -0.3080 | No | ||
| 47 | ITIH1 | 670044 | 9913 | -0.003 | -0.3206 | No | ||
| 48 | FKBP9 | 1400044 | 10046 | -0.005 | -0.3276 | No | ||
| 49 | CANX | 4760402 | 10218 | -0.008 | -0.3367 | No | ||
| 50 | SCUBE1 | 5130551 | 10831 | -0.017 | -0.3695 | No | ||
| 51 | KCNIP2 | 60088 1780324 | 10849 | -0.017 | -0.3702 | No | ||
| 52 | TPD52 | 670463 4610541 | 11503 | -0.028 | -0.4050 | No | ||
| 53 | NUCB2 | 5690181 | 11699 | -0.032 | -0.4150 | No | ||
| 54 | CETN1 | 6020056 | 12098 | -0.041 | -0.4359 | No | ||
| 55 | CALR | 510446 | 12392 | -0.047 | -0.4510 | No | ||
| 56 | RGN | 6200095 | 12565 | -0.052 | -0.4596 | No | ||
| 57 | DMP1 | 4760398 | 12802 | -0.059 | -0.4714 | No | ||
| 58 | HPCAL4 | 2600484 | 13162 | -0.072 | -0.4898 | No | ||
| 59 | DNASE1L2 | 2120400 5700465 | 13244 | -0.076 | -0.4930 | No | ||
| 60 | THBD | 1500092 | 13451 | -0.085 | -0.5029 | No | ||
| 61 | HRC | 2690563 | 13995 | -0.120 | -0.5305 | No | ||
| 62 | PPM2C | 3360209 | 14179 | -0.137 | -0.5383 | No | ||
| 63 | CIB1 | 7100722 | 15504 | -0.413 | -0.6038 | No | ||
| 64 | COMP | 3800273 | 15577 | -0.441 | -0.6012 | No | ||
| 65 | S100A4 | 3780113 | 15765 | -0.528 | -0.6037 | No | ||
| 66 | PPP3CB | 6020156 | 15807 | -0.545 | -0.5979 | No | ||
| 67 | SLC25A12 | 7400731 | 16380 | -0.887 | -0.6159 | Yes | ||
| 68 | FBLN2 | 730601 3440215 | 16538 | -0.991 | -0.6100 | Yes | ||
| 69 | CDH24 | 6980592 | 16544 | -0.995 | -0.5958 | Yes | ||
| 70 | BNIP2 | 1410475 6770088 | 16563 | -0.999 | -0.5822 | Yes | ||
| 71 | PCLO | 580059 3140131 | 16709 | -1.092 | -0.5742 | Yes | ||
| 72 | ATP2A1 | 110309 | 16770 | -1.146 | -0.5608 | Yes | ||
| 73 | CAMKK2 | 5270047 | 16998 | -1.342 | -0.5535 | Yes | ||
| 74 | LETM1 | 2680019 4920113 6220112 | 17311 | -1.729 | -0.5452 | Yes | ||
| 75 | CALM3 | 3390288 | 17601 | -2.209 | -0.5287 | Yes | ||
| 76 | LRPAP1 | 5570253 | 17673 | -2.370 | -0.4981 | Yes | ||
| 77 | S100A13 | 520019 | 18102 | -3.423 | -0.4714 | Yes | ||
| 78 | STIM1 | 6380138 | 18357 | -4.701 | -0.4168 | Yes | ||
| 79 | DNASE1L3 | 670086 | 18418 | -5.251 | -0.3437 | Yes | ||
| 80 | SCIN | 5420180 | 18445 | -5.529 | -0.2647 | Yes | ||
| 81 | S100A9 | 7050528 | 18495 | -6.000 | -0.1802 | Yes | ||
| 82 | S100A8 | 70112 | 18510 | -6.250 | -0.0901 | Yes | ||
| 83 | CDK5R1 | 3870161 | 18529 | -6.586 | 0.0047 | Yes |
