Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_03_wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy_repos |
| Phenotype | phenotype_wtNotch_versus_normalThy.cls#wtNotch_versus_normalThy_repos |
| Upregulated in class | wtNotch |
| GeneSet | SCHUMACHER_MYC_UP |
| Enrichment Score (ES) | 0.76920366 |
| Normalized Enrichment Score (NES) | 1.8195052 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.01057288 |
| FWER p-Value | 0.021 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | BOP1 | 4810040 | 55 | 5.539 | 0.0920 | Yes | ||
| 2 | JTV1 | 460324 | 109 | 4.647 | 0.1689 | Yes | ||
| 3 | NOLC1 | 2350195 | 110 | 4.643 | 0.2485 | Yes | ||
| 4 | LDHA | 2190594 | 205 | 4.012 | 0.3122 | Yes | ||
| 5 | DHODH | 3170072 | 214 | 3.970 | 0.3799 | Yes | ||
| 6 | PRDX4 | 3800039 | 438 | 3.094 | 0.4209 | Yes | ||
| 7 | DDX21 | 6100446 | 460 | 3.031 | 0.4718 | Yes | ||
| 8 | AEBP1 | 6450707 | 607 | 2.684 | 0.5099 | Yes | ||
| 9 | POLD2 | 6400148 | 698 | 2.534 | 0.5485 | Yes | ||
| 10 | NME1 | 770014 | 770 | 2.400 | 0.5859 | Yes | ||
| 11 | MRPL3 | 1170736 5270025 | 1066 | 1.953 | 0.6035 | Yes | ||
| 12 | HSPE1 | 3170438 | 1121 | 1.886 | 0.6329 | Yes | ||
| 13 | PAICS | 610142 | 1131 | 1.879 | 0.6646 | Yes | ||
| 14 | PYCR1 | 6180670 | 1238 | 1.777 | 0.6894 | Yes | ||
| 15 | CTPS | 70451 1740132 | 1539 | 1.499 | 0.6990 | Yes | ||
| 16 | TFRC | 4050551 | 1557 | 1.475 | 0.7233 | Yes | ||
| 17 | SLC39A6 | 6100072 | 1716 | 1.338 | 0.7378 | Yes | ||
| 18 | NEFH | 630239 | 1814 | 1.258 | 0.7541 | Yes | ||
| 19 | FKBP4 | 870035 | 1910 | 1.178 | 0.7692 | Yes | ||
| 20 | POLR2H | 5890242 | 2498 | 0.821 | 0.7517 | No | ||
| 21 | GRSF1 | 2100184 | 2843 | 0.641 | 0.7441 | No | ||
| 22 | CYP51A1 | 4590427 | 2962 | 0.590 | 0.7479 | No | ||
| 23 | PRPS2 | 3140707 | 3042 | 0.556 | 0.7532 | No | ||
| 24 | ACSL1 | 2900520 | 3071 | 0.548 | 0.7611 | No | ||
| 25 | ATP1B3 | 6040128 | 3779 | 0.301 | 0.7282 | No | ||
| 26 | SLC39A14 | 670300 1400093 1990711 | 4157 | 0.226 | 0.7118 | No | ||
| 27 | EBNA1BP2 | 50369 1400433 6040019 | 4561 | 0.173 | 0.6930 | No | ||
| 28 | UCHL3 | 1240735 | 4574 | 0.171 | 0.6953 | No | ||
| 29 | CTSC | 2230739 4670408 | 5070 | 0.127 | 0.6708 | No | ||
| 30 | RANBP1 | 430215 1090180 | 5116 | 0.124 | 0.6705 | No | ||
| 31 | PBEF1 | 1090278 | 5166 | 0.121 | 0.6700 | No | ||
| 32 | DDX10 | 520746 | 6178 | 0.072 | 0.6168 | No | ||
| 33 | RRS1 | 4560551 | 7202 | 0.043 | 0.5624 | No | ||
| 34 | MEST | 4780440 6620292 | 7679 | 0.033 | 0.5374 | No | ||
| 35 | AUH | 5570152 | 8958 | 0.011 | 0.4687 | No | ||
| 36 | AKAP1 | 110148 1740735 2260019 7000563 | 9166 | 0.008 | 0.4577 | No | ||
| 37 | LRP8 | 3610746 5360035 | 9894 | -0.003 | 0.4186 | No | ||
| 38 | SLC16A1 | 50433 | 10203 | -0.007 | 0.4022 | No | ||
| 39 | MTHFD1 | 5900398 6520427 | 10575 | -0.013 | 0.3824 | No | ||
| 40 | AHCY | 4230605 | 11518 | -0.029 | 0.3322 | No | ||
| 41 | FABP5 | 730452 4810497 | 11586 | -0.030 | 0.3291 | No | ||
| 42 | ABCE1 | 4280050 | 12861 | -0.061 | 0.2615 | No | ||
| 43 | IARS | 460528 1580739 1690008 | 13452 | -0.085 | 0.2312 | No | ||
| 44 | VRK1 | 5890603 6900347 | 15028 | -0.263 | 0.1509 | No | ||
| 45 | FXN | 4070500 | 16122 | -0.725 | 0.1045 | No | ||
| 46 | SLC20A1 | 6420014 | 17320 | -1.735 | 0.0698 | No |
