Dataset | Set_03_wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy_repos |
Phenotype | phenotype_wtNotch_versus_normalThy.cls#wtNotch_versus_normalThy_repos |
Upregulated in class | wtNotch |
GeneSet | PENG_RAPAMYCIN_DN |
Enrichment Score (ES) | 0.6625339 |
Normalized Enrichment Score (NES) | 1.8684075 |
Nominal p-value | 0.0 |
FDR q-value | 0.004974209 |
FWER p-Value | 0.0050 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | PFKM | 1990156 5720168 | 4 | 9.552 | 0.0397 | Yes | ||
2 | SLC7A5 | 3310746 | 33 | 6.535 | 0.0655 | Yes | ||
3 | SLC29A1 | 2970379 | 38 | 6.165 | 0.0910 | Yes | ||
4 | TCP1 | 2450100 5130524 | 76 | 5.073 | 0.1102 | Yes | ||
5 | EIF3S9 | 2030068 2120044 | 81 | 5.001 | 0.1309 | Yes | ||
6 | AATF | 5220575 | 123 | 4.556 | 0.1477 | Yes | ||
7 | CYC1 | 2850546 | 124 | 4.555 | 0.1667 | Yes | ||
8 | FASN | 430717 | 162 | 4.262 | 0.1825 | Yes | ||
9 | UBE2M | 2450215 | 179 | 4.166 | 0.1990 | Yes | ||
10 | PA2G4 | 2030463 | 194 | 4.069 | 0.2153 | Yes | ||
11 | C1QBP | 3170452 | 207 | 4.008 | 0.2314 | Yes | ||
12 | CCT6A | 2350368 | 221 | 3.944 | 0.2471 | Yes | ||
13 | RARS | 380390 | 270 | 3.725 | 0.2601 | Yes | ||
14 | PSMD14 | 5690593 | 297 | 3.628 | 0.2738 | Yes | ||
15 | MRPL12 | 3120112 | 320 | 3.528 | 0.2874 | Yes | ||
16 | GM2A | 430095 | 321 | 3.527 | 0.3021 | Yes | ||
17 | NARS | 1660722 | 343 | 3.427 | 0.3153 | Yes | ||
18 | ATF5 | 5670685 | 358 | 3.385 | 0.3287 | Yes | ||
19 | GCN5L2 | 2340609 | 365 | 3.360 | 0.3424 | Yes | ||
20 | CYCS | 2030072 | 384 | 3.284 | 0.3551 | Yes | ||
21 | NOL1 | 4570576 4920044 | 399 | 3.222 | 0.3678 | Yes | ||
22 | UBE2L3 | 1690707 5900242 | 401 | 3.213 | 0.3812 | Yes | ||
23 | DHCR24 | 840600 1050672 6290097 | 409 | 3.188 | 0.3941 | Yes | ||
24 | BCS1L | 5360102 | 439 | 3.094 | 0.4055 | Yes | ||
25 | DDX21 | 6100446 | 460 | 3.031 | 0.4171 | Yes | ||
26 | SRM | 1850097 2480162 | 513 | 2.900 | 0.4264 | Yes | ||
27 | IDH3A | 460332 | 561 | 2.773 | 0.4354 | Yes | ||
28 | ETF1 | 6770075 | 582 | 2.725 | 0.4457 | Yes | ||
29 | DDX3X | 2190020 | 681 | 2.564 | 0.4511 | Yes | ||
30 | NOL5A | 5570139 | 757 | 2.422 | 0.4571 | Yes | ||
31 | NME1 | 770014 | 770 | 2.400 | 0.4665 | Yes | ||
32 | CCT4 | 6380161 | 788 | 2.374 | 0.4755 | Yes | ||
33 | USP10 | 2030736 2450333 | 804 | 2.347 | 0.4845 | Yes | ||
34 | PSMD8 | 630142 | 846 | 2.266 | 0.4917 | Yes | ||
35 | PSMC2 | 7040010 | 854 | 2.254 | 0.5008 | Yes | ||
36 | NMT1 | 5810152 | 867 | 2.236 | 0.5095 | Yes | ||
37 | SCD | 2680441 | 909 | 2.162 | 0.5163 | Yes | ||
38 | TIMM17A | 130092 | 934 | 2.131 | 0.5239 | Yes | ||
39 | TOMM40 | 6110017 | 939 | 2.111 | 0.5325 | Yes | ||
40 | SLC3A2 | 5270358 | 994 | 2.046 | 0.5381 | Yes | ||
41 | SF3A3 | 6660603 | 1024 | 1.998 | 0.5449 | Yes | ||
42 | CCT2 | 1690113 | 1096 | 1.916 | 0.5490 | Yes | ||
43 | HSPE1 | 3170438 | 1121 | 1.886 | 0.5556 | Yes | ||
44 | HYOU1 | 3060465 | 1126 | 1.883 | 0.5633 | Yes | ||
45 | CCT5 | 1050670 | 1142 | 1.862 | 0.5702 | Yes | ||
46 | CCNC | 3390750 | 1166 | 1.846 | 0.5767 | Yes | ||
47 | PITPNB | 5130039 | 1225 | 1.786 | 0.5810 | Yes | ||
48 | RAE1 | 7050121 | 1237 | 1.778 | 0.5878 | Yes | ||
49 | PSMB5 | 6290242 | 1272 | 1.738 | 0.5932 | Yes | ||
50 | PGAM1 | 2570133 | 1304 | 1.712 | 0.5987 | Yes | ||
51 | RTN4 | 50725 630647 870097 870184 | 1318 | 1.704 | 0.6051 | Yes | ||
52 | CSE1L | 3850086 | 1334 | 1.684 | 0.6114 | Yes | ||
53 | ASNS | 110368 7100687 | 1366 | 1.659 | 0.6166 | Yes | ||
54 | EIF2B2 | 4290048 | 1464 | 1.570 | 0.6179 | Yes | ||
55 | CTPS | 70451 1740132 | 1539 | 1.499 | 0.6202 | Yes | ||
56 | TFRC | 4050551 | 1557 | 1.475 | 0.6254 | Yes | ||
57 | EIF4G1 | 4070446 | 1619 | 1.417 | 0.6280 | Yes | ||
58 | MRPS12 | 4210707 6110341 | 1620 | 1.416 | 0.6339 | Yes | ||
59 | ETFA | 50347 5690040 6370044 | 1626 | 1.412 | 0.6395 | Yes | ||
60 | IDH3B | 5690070 | 1749 | 1.306 | 0.6384 | Yes | ||
61 | FKBP4 | 870035 | 1910 | 1.178 | 0.6346 | Yes | ||
62 | GLO1 | 7040692 | 1924 | 1.169 | 0.6388 | Yes | ||
63 | AK2 | 4590458 4760195 6110097 | 1965 | 1.135 | 0.6414 | Yes | ||
64 | WBSCR22 | 3130070 4120551 5570433 | 2071 | 1.051 | 0.6401 | Yes | ||
65 | HSPA8 | 2120315 1050132 6550746 | 2111 | 1.030 | 0.6423 | Yes | ||
66 | YARS | 70739 | 2128 | 1.018 | 0.6457 | Yes | ||
67 | SNRPA1 | 1050735 6110131 | 2142 | 1.011 | 0.6492 | Yes | ||
68 | PGK1 | 1570494 630300 | 2167 | 1.001 | 0.6521 | Yes | ||
69 | PPP2R2A | 2900014 5700575 | 2249 | 0.978 | 0.6518 | Yes | ||
70 | EIF2B4 | 5270082 | 2258 | 0.974 | 0.6554 | Yes | ||
71 | ATP5G3 | 4230551 | 2327 | 0.925 | 0.6556 | Yes | ||
72 | SDHB | 3120398 4780113 3710435 | 2417 | 0.872 | 0.6544 | Yes | ||
73 | MORF4L2 | 6450133 | 2431 | 0.863 | 0.6573 | Yes | ||
74 | PRDX3 | 1690035 | 2463 | 0.843 | 0.6591 | Yes | ||
75 | TRIP13 | 6860341 | 2466 | 0.841 | 0.6625 | Yes | ||
76 | AHSA1 | 2030520 | 2652 | 0.735 | 0.6556 | No | ||
77 | NDUFS3 | 1690136 5340528 | 2678 | 0.720 | 0.6572 | No | ||
78 | MLF2 | 1940176 | 2775 | 0.670 | 0.6548 | No | ||
79 | PTBP1 | 4070736 | 2814 | 0.653 | 0.6555 | No | ||
80 | HSPA5 | 5130671 | 2859 | 0.636 | 0.6558 | No | ||
81 | TUBG1 | 3140204 | 2914 | 0.609 | 0.6554 | No | ||
82 | INPP5E | 6100619 | 2988 | 0.579 | 0.6538 | No | ||
83 | ADRM1 | 670333 5690162 | 3087 | 0.543 | 0.6508 | No | ||
84 | COX7B | 2340504 | 3094 | 0.540 | 0.6527 | No | ||
85 | NDUFA9 | 2260280 | 3148 | 0.519 | 0.6520 | No | ||
86 | RBBP6 | 2320129 | 3246 | 0.481 | 0.6488 | No | ||
87 | MAPKAPK3 | 630520 | 3289 | 0.462 | 0.6484 | No | ||
88 | BMP1 | 380594 2940576 3710593 | 3320 | 0.452 | 0.6487 | No | ||
89 | TARS | 50440 1340086 | 3359 | 0.443 | 0.6485 | No | ||
90 | GOT2 | 4570164 5220450 | 3364 | 0.442 | 0.6501 | No | ||
91 | DAP3 | 1660528 2120039 5420593 | 3459 | 0.405 | 0.6467 | No | ||
92 | EBP | 2760292 | 3546 | 0.376 | 0.6436 | No | ||
93 | CDC25A | 3800184 | 3565 | 0.371 | 0.6442 | No | ||
94 | KPNA3 | 7040088 | 3572 | 0.369 | 0.6454 | No | ||
95 | ICT1 | 430138 | 3622 | 0.345 | 0.6442 | No | ||
96 | ATP1B3 | 6040128 | 3779 | 0.301 | 0.6370 | No | ||
97 | WNT10B | 510050 | 3781 | 0.301 | 0.6382 | No | ||
98 | SLC39A14 | 670300 1400093 1990711 | 4157 | 0.226 | 0.6188 | No | ||
99 | AMD1 | 6290128 | 4209 | 0.217 | 0.6169 | No | ||
100 | DNAJA1 | 1660010 2320358 6840136 | 4387 | 0.193 | 0.6082 | No | ||
101 | EIF4G2 | 3800575 6860184 | 4422 | 0.188 | 0.6071 | No | ||
102 | ACAT2 | 2680400 3610440 | 4495 | 0.180 | 0.6039 | No | ||
103 | ARMET | 5130670 | 4547 | 0.174 | 0.6019 | No | ||
104 | EBNA1BP2 | 50369 1400433 6040019 | 4561 | 0.173 | 0.6019 | No | ||
105 | VCP | 5340168 | 4860 | 0.144 | 0.5864 | No | ||
106 | ARF1 | 3840291 | 4955 | 0.135 | 0.5818 | No | ||
107 | SLC1A5 | 670133 3140020 | 4983 | 0.133 | 0.5809 | No | ||
108 | CTSC | 2230739 4670408 | 5070 | 0.127 | 0.5768 | No | ||
109 | GORASP2 | 2970059 4060309 7040706 | 5101 | 0.125 | 0.5757 | No | ||
110 | PPIB | 4280450 | 5119 | 0.124 | 0.5753 | No | ||
111 | RAB1A | 2370671 | 5886 | 0.083 | 0.5341 | No | ||
112 | GCDH | 2190324 4280347 | 6451 | 0.062 | 0.5038 | No | ||
113 | PICALM | 1940280 | 6457 | 0.062 | 0.5038 | No | ||
114 | IDI1 | 1450736 | 6620 | 0.057 | 0.4952 | No | ||
115 | TDG | 2900358 2940079 | 7002 | 0.048 | 0.4748 | No | ||
116 | SREBF1 | 4780333 | 7022 | 0.047 | 0.4739 | No | ||
117 | GTF2A2 | 2230184 | 7496 | 0.037 | 0.4485 | No | ||
118 | COPB2 | 610154 | 7905 | 0.029 | 0.4265 | No | ||
119 | CAPZA2 | 110427 4590064 | 8058 | 0.026 | 0.4183 | No | ||
120 | CALU | 2680403 3520056 4610348 5720176 6130121 | 8083 | 0.026 | 0.4171 | No | ||
121 | PTDSS1 | 6020215 | 8155 | 0.024 | 0.4134 | No | ||
122 | HCCS | 670397 3170341 | 8297 | 0.022 | 0.4058 | No | ||
123 | NP | 2630577 3120142 5670068 6290039 | 8368 | 0.021 | 0.4021 | No | ||
124 | ATP6V0C | 1780609 | 8632 | 0.016 | 0.3879 | No | ||
125 | PTRF | 2260204 | 8885 | 0.012 | 0.3743 | No | ||
126 | RTCD1 | 7000041 | 8970 | 0.011 | 0.3698 | No | ||
127 | PSMD5 | 3940139 4570041 | 9264 | 0.006 | 0.3540 | No | ||
128 | IFI30 | 730309 2940500 | 9446 | 0.004 | 0.3442 | No | ||
129 | WDR18 | 6020102 | 9555 | 0.002 | 0.3383 | No | ||
130 | BTK | 3130044 | 9841 | -0.002 | 0.3229 | No | ||
131 | PPIF | 1740059 | 10274 | -0.008 | 0.2995 | No | ||
132 | ACVRL1 | 3290600 | 10276 | -0.008 | 0.2995 | No | ||
133 | BYSL | 3170110 | 11054 | -0.021 | 0.2574 | No | ||
134 | PHB | 2260739 | 11141 | -0.022 | 0.2529 | No | ||
135 | POLR2B | 3780138 | 11796 | -0.034 | 0.2176 | No | ||
136 | CHUK | 7050736 | 11886 | -0.036 | 0.2129 | No | ||
137 | P2RX5 | 5570427 6130435 | 12030 | -0.039 | 0.2053 | No | ||
138 | SYNCRIP | 1690195 3140113 4670279 | 12153 | -0.042 | 0.1989 | No | ||
139 | MYCBP | 4280528 | 12471 | -0.049 | 0.1819 | No | ||
140 | PAPOLA | 4200286 4850112 | 12676 | -0.055 | 0.1710 | No | ||
141 | EEF1E1 | 4540711 | 12817 | -0.060 | 0.1637 | No | ||
142 | BCAP31 | 1190520 | 13260 | -0.076 | 0.1401 | No | ||
143 | RPS26 | 510139 | 13607 | -0.093 | 0.1217 | No | ||
144 | NUP98 | 2850465 | 13883 | -0.112 | 0.1073 | No | ||
145 | MMP15 | 5900717 | 14823 | -0.219 | 0.0573 | No | ||
146 | PSMD11 | 2340538 6510053 | 14886 | -0.231 | 0.0549 | No | ||
147 | GSPT1 | 5420050 | 15031 | -0.263 | 0.0482 | No | ||
148 | RNASEH1 | 3840575 | 15188 | -0.301 | 0.0410 | No | ||
149 | COX11 | 1580121 | 15243 | -0.323 | 0.0394 | No | ||
150 | EXTL3 | 540309 3130215 5860500 | 15268 | -0.330 | 0.0395 | No | ||
151 | S100A4 | 3780113 | 15765 | -0.528 | 0.0148 | No | ||
152 | ALDH4A1 | 2450450 | 16113 | -0.718 | -0.0010 | No | ||
153 | CDK4 | 540075 4540600 | 16170 | -0.750 | -0.0009 | No | ||
154 | EMP3 | 1500722 1570039 | 16298 | -0.836 | -0.0043 | No | ||
155 | TIMM44 | 4670746 4730050 | 16306 | -0.844 | -0.0012 | No | ||
156 | UCHL1 | 1230066 | 16391 | -0.893 | -0.0020 | No | ||
157 | HSPA4 | 1050170 3450309 | 16403 | -0.901 | 0.0012 | No | ||
158 | PTPN1 | 2650056 | 16631 | -1.030 | -0.0068 | No | ||
159 | SQLE | 50180 940092 | 16720 | -1.102 | -0.0070 | No | ||
160 | CHERP | 1240594 | 16844 | -1.201 | -0.0087 | No | ||
161 | RABGGTB | 3120037 | 16930 | -1.272 | -0.0080 | No | ||
162 | XPO6 | 3940019 | 16934 | -1.277 | -0.0028 | No | ||
163 | JTB | 6980400 | 17028 | -1.377 | -0.0021 | No | ||
164 | LIMK2 | 2650446 4050164 | 17035 | -1.382 | 0.0034 | No | ||
165 | RAB14 | 6860139 | 17120 | -1.499 | 0.0051 | No | ||
166 | NXF1 | 1570377 | 17179 | -1.567 | 0.0085 | No | ||
167 | NPM3 | 3610300 | 17454 | -1.959 | 0.0018 | No | ||
168 | CD47 | 1850603 | 17731 | -2.476 | -0.0028 | No | ||
169 | GTF3C1 | 1990368 4210037 | 17918 | -2.892 | -0.0008 | No | ||
170 | XBP1 | 3840594 | 18340 | -4.607 | -0.0044 | No | ||
171 | PIP5K1A | 4560672 | 18343 | -4.618 | 0.0148 | No |