Dataset | Set_03_wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy_repos |
Phenotype | phenotype_wtNotch_versus_normalThy.cls#wtNotch_versus_normalThy_repos |
Upregulated in class | wtNotch |
GeneSet | PENG_GLUTAMINE_DN |
Enrichment Score (ES) | 0.5938951 |
Normalized Enrichment Score (NES) | 1.7335516 |
Nominal p-value | 0.0 |
FDR q-value | 0.031849205 |
FWER p-Value | 0.177 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | EIF2B5 | 430315 6900400 | 10 | 8.726 | 0.0233 | Yes | ||
2 | VARS2 | 1410017 3800114 4210270 | 31 | 6.628 | 0.0403 | Yes | ||
3 | FUS | 4760619 | 36 | 6.203 | 0.0570 | Yes | ||
4 | SLC29A1 | 2970379 | 38 | 6.165 | 0.0738 | Yes | ||
5 | ALDOA | 6290672 | 47 | 5.798 | 0.0892 | Yes | ||
6 | BOP1 | 4810040 | 55 | 5.539 | 0.1039 | Yes | ||
7 | FBL | 5130020 | 61 | 5.340 | 0.1182 | Yes | ||
8 | TCP1 | 2450100 5130524 | 76 | 5.073 | 0.1313 | Yes | ||
9 | NOLC1 | 2350195 | 110 | 4.643 | 0.1422 | Yes | ||
10 | CYC1 | 2850546 | 124 | 4.555 | 0.1539 | Yes | ||
11 | RUVBL2 | 1190377 | 129 | 4.511 | 0.1660 | Yes | ||
12 | FASN | 430717 | 162 | 4.262 | 0.1759 | Yes | ||
13 | UBE2M | 2450215 | 179 | 4.166 | 0.1864 | Yes | ||
14 | PA2G4 | 2030463 | 194 | 4.069 | 0.1968 | Yes | ||
15 | SNRP70 | 4200181 | 196 | 4.068 | 0.2078 | Yes | ||
16 | LDHA | 2190594 | 205 | 4.012 | 0.2183 | Yes | ||
17 | C1QBP | 3170452 | 207 | 4.008 | 0.2292 | Yes | ||
18 | CCT6A | 2350368 | 221 | 3.944 | 0.2393 | Yes | ||
19 | TBL3 | 6020575 | 222 | 3.918 | 0.2500 | Yes | ||
20 | PIK3R3 | 1770333 | 268 | 3.727 | 0.2577 | Yes | ||
21 | SLC19A1 | 6770139 | 289 | 3.667 | 0.2666 | Yes | ||
22 | MRPL12 | 3120112 | 320 | 3.528 | 0.2746 | Yes | ||
23 | RNF126 | 2650672 4560563 | 324 | 3.517 | 0.2841 | Yes | ||
24 | CAD | 2340717 | 350 | 3.407 | 0.2920 | Yes | ||
25 | SYNGR2 | 4050332 4560091 6130348 | 380 | 3.310 | 0.2995 | Yes | ||
26 | CYCS | 2030072 | 384 | 3.284 | 0.3083 | Yes | ||
27 | NUDC | 4780025 | 395 | 3.235 | 0.3165 | Yes | ||
28 | NOL1 | 4570576 4920044 | 399 | 3.222 | 0.3252 | Yes | ||
29 | DHCR24 | 840600 1050672 6290097 | 409 | 3.188 | 0.3334 | Yes | ||
30 | IFRD2 | 4150110 | 413 | 3.168 | 0.3419 | Yes | ||
31 | TCEB1 | 1170619 | 419 | 3.147 | 0.3502 | Yes | ||
32 | PRDX4 | 3800039 | 438 | 3.094 | 0.3577 | Yes | ||
33 | ALG3 | 2650647 7100131 | 449 | 3.062 | 0.3655 | Yes | ||
34 | DDX21 | 6100446 | 460 | 3.031 | 0.3732 | Yes | ||
35 | SRM | 1850097 2480162 | 513 | 2.900 | 0.3783 | Yes | ||
36 | MRPL28 | 3520673 | 533 | 2.849 | 0.3850 | Yes | ||
37 | NCL | 2360463 4540279 | 534 | 2.844 | 0.3928 | Yes | ||
38 | CCND1 | 460524 770309 3120576 6980398 | 547 | 2.823 | 0.3999 | Yes | ||
39 | IDH3A | 460332 | 561 | 2.773 | 0.4067 | Yes | ||
40 | GMPS | 460670 | 614 | 2.679 | 0.4112 | Yes | ||
41 | DDX1 | 3450047 | 625 | 2.660 | 0.4179 | Yes | ||
42 | SNRPF | 3170280 | 640 | 2.631 | 0.4243 | Yes | ||
43 | PIK3R2 | 1660193 | 656 | 2.603 | 0.4306 | Yes | ||
44 | LMNB1 | 5890292 6020008 | 756 | 2.426 | 0.4319 | Yes | ||
45 | NOL5A | 5570139 | 757 | 2.422 | 0.4385 | Yes | ||
46 | NME1 | 770014 | 770 | 2.400 | 0.4444 | Yes | ||
47 | PSMD12 | 730044 | 790 | 2.371 | 0.4498 | Yes | ||
48 | KARS | 6520575 | 792 | 2.364 | 0.4562 | Yes | ||
49 | ABCF1 | 2630707 2760273 3520725 | 812 | 2.333 | 0.4616 | Yes | ||
50 | PSMF1 | 5340056 | 830 | 2.303 | 0.4669 | Yes | ||
51 | PSMD8 | 630142 | 846 | 2.266 | 0.4723 | Yes | ||
52 | SLC5A6 | 2570438 | 849 | 2.263 | 0.4784 | Yes | ||
53 | NMT1 | 5810152 | 867 | 2.236 | 0.4835 | Yes | ||
54 | SCD | 2680441 | 909 | 2.162 | 0.4872 | Yes | ||
55 | TIMM17A | 130092 | 934 | 2.131 | 0.4917 | Yes | ||
56 | TOMM40 | 6110017 | 939 | 2.111 | 0.4973 | Yes | ||
57 | DDX18 | 6980619 | 991 | 2.055 | 0.5001 | Yes | ||
58 | MRPL3 | 1170736 5270025 | 1066 | 1.953 | 0.5014 | Yes | ||
59 | VDAC1 | 4760059 | 1092 | 1.925 | 0.5053 | Yes | ||
60 | CCT2 | 1690113 | 1096 | 1.916 | 0.5104 | Yes | ||
61 | FKBP2 | 2320025 | 1097 | 1.915 | 0.5156 | Yes | ||
62 | HSPE1 | 3170438 | 1121 | 1.886 | 0.5195 | Yes | ||
63 | PAICS | 610142 | 1131 | 1.879 | 0.5241 | Yes | ||
64 | CCT5 | 1050670 | 1142 | 1.862 | 0.5287 | Yes | ||
65 | HPRT1 | 1690398 4920619 6350170 | 1182 | 1.834 | 0.5316 | Yes | ||
66 | PSMB3 | 4280594 | 1211 | 1.799 | 0.5349 | Yes | ||
67 | MAPRE2 | 1660435 5860403 | 1301 | 1.715 | 0.5348 | Yes | ||
68 | PGAM1 | 2570133 | 1304 | 1.712 | 0.5394 | Yes | ||
69 | CSE1L | 3850086 | 1334 | 1.684 | 0.5424 | Yes | ||
70 | PSMB6 | 2690711 | 1374 | 1.653 | 0.5448 | Yes | ||
71 | ATR | 6860273 | 1483 | 1.551 | 0.5431 | Yes | ||
72 | LAMB3 | 7100301 | 1520 | 1.514 | 0.5453 | Yes | ||
73 | ATP2A2 | 1090075 3990279 | 1522 | 1.512 | 0.5494 | Yes | ||
74 | CTPS | 70451 1740132 | 1539 | 1.499 | 0.5526 | Yes | ||
75 | UMPS | 2340541 4730438 | 1546 | 1.490 | 0.5563 | Yes | ||
76 | TFRC | 4050551 | 1557 | 1.475 | 0.5598 | Yes | ||
77 | PSMD3 | 1400647 | 1574 | 1.461 | 0.5629 | Yes | ||
78 | EIF4G1 | 4070446 | 1619 | 1.417 | 0.5644 | Yes | ||
79 | MRPS12 | 4210707 6110341 | 1620 | 1.416 | 0.5683 | Yes | ||
80 | PES1 | 2470427 | 1642 | 1.402 | 0.5710 | Yes | ||
81 | HRAS | 1980551 | 1652 | 1.391 | 0.5743 | Yes | ||
82 | SFRS2 | 50707 380593 | 1695 | 1.356 | 0.5757 | Yes | ||
83 | PRPS1 | 6350129 | 1706 | 1.347 | 0.5788 | Yes | ||
84 | TGFB1 | 1940162 | 1841 | 1.237 | 0.5749 | Yes | ||
85 | CDC20 | 3440017 3440044 6220088 | 1858 | 1.226 | 0.5774 | Yes | ||
86 | PDCD4 | 3360403 5690110 | 1892 | 1.193 | 0.5789 | Yes | ||
87 | FKBP4 | 870035 | 1910 | 1.178 | 0.5811 | Yes | ||
88 | AK2 | 4590458 4760195 6110097 | 1965 | 1.135 | 0.5813 | Yes | ||
89 | MYD88 | 2100717 | 1997 | 1.105 | 0.5826 | Yes | ||
90 | COPS3 | 780039 | 2047 | 1.070 | 0.5829 | Yes | ||
91 | BZW1 | 460270 | 2078 | 1.049 | 0.5841 | Yes | ||
92 | PRDX1 | 5720253 | 2080 | 1.048 | 0.5869 | Yes | ||
93 | HSPA8 | 2120315 1050132 6550746 | 2111 | 1.030 | 0.5881 | Yes | ||
94 | SNRPA1 | 1050735 6110131 | 2142 | 1.011 | 0.5892 | Yes | ||
95 | SMARCC1 | 5080019 7100047 | 2150 | 1.007 | 0.5916 | Yes | ||
96 | PPP2R2A | 2900014 5700575 | 2249 | 0.978 | 0.5890 | Yes | ||
97 | EIF2B4 | 5270082 | 2258 | 0.974 | 0.5912 | Yes | ||
98 | ATP5G3 | 4230551 | 2327 | 0.925 | 0.5900 | Yes | ||
99 | NUP160 | 1990551 | 2354 | 0.909 | 0.5911 | Yes | ||
100 | SEC61B | 840113 4540687 | 2369 | 0.902 | 0.5928 | Yes | ||
101 | MORF4L2 | 6450133 | 2431 | 0.863 | 0.5918 | Yes | ||
102 | TRIP13 | 6860341 | 2466 | 0.841 | 0.5923 | Yes | ||
103 | SC4MOL | 3140524 | 2486 | 0.829 | 0.5935 | Yes | ||
104 | CELSR2 | 2320148 6220152 | 2520 | 0.808 | 0.5939 | Yes | ||
105 | AHSA1 | 2030520 | 2652 | 0.735 | 0.5888 | No | ||
106 | RQCD1 | 1850139 | 2706 | 0.708 | 0.5878 | No | ||
107 | MLF2 | 1940176 | 2775 | 0.670 | 0.5860 | No | ||
108 | HSPA5 | 5130671 | 2859 | 0.636 | 0.5832 | No | ||
109 | TUBG1 | 3140204 | 2914 | 0.609 | 0.5819 | No | ||
110 | ADRM1 | 670333 5690162 | 3087 | 0.543 | 0.5740 | No | ||
111 | RBBP6 | 2320129 | 3246 | 0.481 | 0.5668 | No | ||
112 | SGTA | 3940154 | 3341 | 0.447 | 0.5629 | No | ||
113 | SF3B4 | 110072 | 3472 | 0.402 | 0.5569 | No | ||
114 | EBP | 2760292 | 3546 | 0.376 | 0.5540 | No | ||
115 | CDC25A | 3800184 | 3565 | 0.371 | 0.5540 | No | ||
116 | DHX15 | 870632 | 3655 | 0.335 | 0.5501 | No | ||
117 | HNRPL | 4210593 | 3675 | 0.330 | 0.5499 | No | ||
118 | ATP1B3 | 6040128 | 3779 | 0.301 | 0.5452 | No | ||
119 | SLC29A2 | 3290497 | 3888 | 0.278 | 0.5400 | No | ||
120 | TARDBP | 870390 2350093 | 3982 | 0.257 | 0.5357 | No | ||
121 | ALG8 | 4150497 4780500 6290563 | 4098 | 0.235 | 0.5301 | No | ||
122 | AMD1 | 6290128 | 4209 | 0.217 | 0.5247 | No | ||
123 | DNAJA1 | 1660010 2320358 6840136 | 4387 | 0.193 | 0.5156 | No | ||
124 | EIF4G2 | 3800575 6860184 | 4422 | 0.188 | 0.5142 | No | ||
125 | ACAT2 | 2680400 3610440 | 4495 | 0.180 | 0.5108 | No | ||
126 | UBE2N | 520369 2900047 | 4546 | 0.174 | 0.5086 | No | ||
127 | ARMET | 5130670 | 4547 | 0.174 | 0.5091 | No | ||
128 | EBNA1BP2 | 50369 1400433 6040019 | 4561 | 0.173 | 0.5088 | No | ||
129 | VCP | 5340168 | 4860 | 0.144 | 0.4930 | No | ||
130 | CTSC | 2230739 4670408 | 5070 | 0.127 | 0.4820 | No | ||
131 | PPIB | 4280450 | 5119 | 0.124 | 0.4797 | No | ||
132 | CHD4 | 5420059 6130338 6380717 | 5129 | 0.123 | 0.4796 | No | ||
133 | PSME4 | 380348 1770131 | 5651 | 0.094 | 0.4515 | No | ||
134 | ERF | 110551 1770278 | 5690 | 0.092 | 0.4497 | No | ||
135 | POLR2C | 1690020 | 5718 | 0.091 | 0.4485 | No | ||
136 | PFKP | 70138 6760040 1170278 | 5877 | 0.084 | 0.4401 | No | ||
137 | GCDH | 2190324 4280347 | 6451 | 0.062 | 0.4091 | No | ||
138 | IDI1 | 1450736 | 6620 | 0.057 | 0.4001 | No | ||
139 | DNAJB6 | 2810309 5570451 | 6772 | 0.053 | 0.3921 | No | ||
140 | SSB | 460286 3140717 | 6856 | 0.051 | 0.3877 | No | ||
141 | TDG | 2900358 2940079 | 7002 | 0.048 | 0.3799 | No | ||
142 | PSMA6 | 50609 | 7110 | 0.045 | 0.3742 | No | ||
143 | RRS1 | 4560551 | 7202 | 0.043 | 0.3694 | No | ||
144 | PTDSS1 | 6020215 | 8155 | 0.024 | 0.3177 | No | ||
145 | XPO1 | 540707 | 8282 | 0.022 | 0.3109 | No | ||
146 | FDFT1 | 5340039 | 8355 | 0.021 | 0.3071 | No | ||
147 | NP | 2630577 3120142 5670068 6290039 | 8368 | 0.021 | 0.3065 | No | ||
148 | GRIN2A | 6550538 | 8547 | 0.018 | 0.2968 | No | ||
149 | ODC1 | 5670168 | 9071 | 0.009 | 0.2684 | No | ||
150 | MPHOSPH10 | 6860114 | 9140 | 0.008 | 0.2647 | No | ||
151 | IFI30 | 730309 2940500 | 9446 | 0.004 | 0.2482 | No | ||
152 | INHBC | 3780242 | 9799 | -0.001 | 0.2290 | No | ||
153 | BTK | 3130044 | 9841 | -0.002 | 0.2268 | No | ||
154 | XRCC5 | 7100286 | 10049 | -0.005 | 0.2156 | No | ||
155 | PPIF | 1740059 | 10274 | -0.008 | 0.2034 | No | ||
156 | MTHFD1 | 5900398 6520427 | 10575 | -0.013 | 0.1871 | No | ||
157 | ZMPSTE24 | 1090112 2030593 3780129 4590044 | 10589 | -0.013 | 0.1865 | No | ||
158 | BYSL | 3170110 | 11054 | -0.021 | 0.1613 | No | ||
159 | PHB | 2260739 | 11141 | -0.022 | 0.1567 | No | ||
160 | DHCR7 | 1470138 | 11927 | -0.037 | 0.1141 | No | ||
161 | DHX9 | 60017 1170095 2260014 | 12123 | -0.041 | 0.1036 | No | ||
162 | SYNCRIP | 1690195 3140113 4670279 | 12153 | -0.042 | 0.1021 | No | ||
163 | CALR | 510446 | 12392 | -0.047 | 0.0893 | No | ||
164 | SNRPB2 | 5720577 | 12674 | -0.055 | 0.0742 | No | ||
165 | EEF1E1 | 4540711 | 12817 | -0.060 | 0.0666 | No | ||
166 | GJB1 | 1240441 | 13196 | -0.074 | 0.0463 | No | ||
167 | BCAP31 | 1190520 | 13260 | -0.076 | 0.0431 | No | ||
168 | EIF5 | 6380750 | 13457 | -0.086 | 0.0326 | No | ||
169 | RPS26 | 510139 | 13607 | -0.093 | 0.0248 | No | ||
170 | NUP98 | 2850465 | 13883 | -0.112 | 0.0101 | No | ||
171 | METTL1 | 4540670 5860162 7040433 | 14105 | -0.129 | -0.0015 | No | ||
172 | KPNA2 | 3450114 | 14510 | -0.169 | -0.0230 | No | ||
173 | RBM14 | 5340731 5690315 | 14596 | -0.180 | -0.0272 | No | ||
174 | RPLP2 | 5290020 | 14619 | -0.184 | -0.0279 | No | ||
175 | ADCY3 | 2350347 3440242 | 14667 | -0.190 | -0.0299 | No | ||
176 | MMP15 | 5900717 | 14823 | -0.219 | -0.0377 | No | ||
177 | OGFR | 5700397 | 14855 | -0.225 | -0.0388 | No | ||
178 | ILF2 | 2900253 | 14869 | -0.228 | -0.0389 | No | ||
179 | PSMD11 | 2340538 6510053 | 14886 | -0.231 | -0.0391 | No | ||
180 | CCNB1 | 4590433 4780372 | 14993 | -0.257 | -0.0442 | No | ||
181 | GSPT1 | 5420050 | 15031 | -0.263 | -0.0455 | No | ||
182 | RNASEH1 | 3840575 | 15188 | -0.301 | -0.0531 | No | ||
183 | UBE2G2 | 1240035 3870184 | 15294 | -0.337 | -0.0579 | No | ||
184 | MRPL23 | 4070142 | 15378 | -0.362 | -0.0615 | No | ||
185 | DOK4 | 4060452 | 15636 | -0.463 | -0.0742 | No | ||
186 | COG2 | 5900129 | 15645 | -0.466 | -0.0733 | No | ||
187 | SLC4A7 | 2370056 | 15867 | -0.579 | -0.0838 | No | ||
188 | SFRS1 | 2360440 | 15931 | -0.616 | -0.0855 | No | ||
189 | GOLGA1 | 5860471 | 15974 | -0.641 | -0.0860 | No | ||
190 | EMP3 | 1500722 1570039 | 16298 | -0.836 | -0.1013 | No | ||
191 | PTPN6 | 4230128 | 16387 | -0.891 | -0.1037 | No | ||
192 | HSPA4 | 1050170 3450309 | 16403 | -0.901 | -0.1020 | No | ||
193 | PRPF4 | 430301 2970364 | 16521 | -0.978 | -0.1057 | No | ||
194 | HNRPA2B1 | 1240619 6200161 6200494 6980408 | 16560 | -0.999 | -0.1051 | No | ||
195 | ME2 | 5080121 | 16596 | -1.013 | -0.1042 | No | ||
196 | TOP1 | 770471 4060632 6650324 | 16657 | -1.051 | -0.1046 | No | ||
197 | MAZ | 3360121 6940750 | 16660 | -1.052 | -0.1018 | No | ||
198 | PCBP1 | 1050088 | 16705 | -1.090 | -0.1013 | No | ||
199 | SQLE | 50180 940092 | 16720 | -1.102 | -0.0990 | No | ||
200 | CLIC1 | 110600 | 16739 | -1.114 | -0.0969 | No | ||
201 | PABPN1 | 460519 | 16839 | -1.197 | -0.0991 | No | ||
202 | RABGGTB | 3120037 | 16930 | -1.272 | -0.1005 | No | ||
203 | LIMK2 | 2650446 4050164 | 17035 | -1.382 | -0.1024 | No | ||
204 | IDH1 | 1990021 | 17046 | -1.408 | -0.0991 | No | ||
205 | SFPQ | 4760110 | 17096 | -1.466 | -0.0977 | No | ||
206 | ARS2 | 2370348 4920577 6840427 | 17218 | -1.623 | -0.0999 | No | ||
207 | YPEL1 | 6590435 | 17232 | -1.635 | -0.0961 | No | ||
208 | RANGAP1 | 2320593 6650601 | 17256 | -1.669 | -0.0928 | No | ||
209 | HNRPAB | 540504 | 17271 | -1.689 | -0.0890 | No | ||
210 | PFN1 | 6130132 | 17292 | -1.714 | -0.0854 | No | ||
211 | ACLY | 1740609 | 17301 | -1.723 | -0.0811 | No | ||
212 | EIF5A | 1500059 5290022 6370026 | 17435 | -1.918 | -0.0831 | No | ||
213 | MYST1 | 2190397 | 17528 | -2.083 | -0.0824 | No | ||
214 | PPP1R10 | 110136 3170725 3610484 | 17533 | -2.092 | -0.0769 | No | ||
215 | IMPDH1 | 3190735 7050546 | 17606 | -2.217 | -0.0748 | No | ||
216 | SRRM1 | 6110025 | 17716 | -2.447 | -0.0740 | No | ||
217 | TAP1 | 4050047 | 17717 | -2.447 | -0.0673 | No | ||
218 | ADAM19 | 5340075 | 17753 | -2.529 | -0.0623 | No | ||
219 | STAT1 | 6510204 6590553 | 17835 | -2.706 | -0.0594 | No | ||
220 | MAP3K11 | 7000039 | 17928 | -2.933 | -0.0564 | No | ||
221 | ERH | 1770156 4570148 | 17939 | -2.963 | -0.0488 | No | ||
222 | DYRK1A | 3190181 | 18295 | -4.333 | -0.0563 | No | ||
223 | XBP1 | 3840594 | 18340 | -4.607 | -0.0461 | No | ||
224 | DNAJB1 | 1090041 | 18371 | -4.807 | -0.0346 | No | ||
225 | SRPK1 | 450110 | 18396 | -5.003 | -0.0223 | No | ||
226 | HS6ST1 | 4760373 | 18424 | -5.303 | -0.0092 | No | ||
227 | PRODH | 1240452 | 18555 | -7.192 | 0.0033 | No |