Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_03_wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy_repos |
| Phenotype | phenotype_wtNotch_versus_normalThy.cls#wtNotch_versus_normalThy_repos |
| Upregulated in class | normalThy |
| GeneSet | FLECHNER_KIDNEY_TRANSPLANT_REJECTION_UP |
| Enrichment Score (ES) | -0.65249556 |
| Normalized Enrichment Score (NES) | -1.5722966 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.25999296 |
| FWER p-Value | 0.99 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | ADAM15 | 5890707 | 103 | 4.725 | 0.0265 | No | ||
| 2 | LGALS9 | 1230079 2640181 2970398 | 448 | 3.064 | 0.0288 | No | ||
| 3 | ACTB | 1660736 2030204 2060215 5050047 | 665 | 2.589 | 0.0347 | No | ||
| 4 | CD14 | 5570600 | 887 | 2.203 | 0.0377 | No | ||
| 5 | ECGF1 | 1990685 | 1017 | 2.012 | 0.0444 | No | ||
| 6 | FCGR3A | 3840184 | 1172 | 1.839 | 0.0486 | No | ||
| 7 | PTPRC | 130402 5290148 | 1316 | 1.706 | 0.0525 | No | ||
| 8 | LCP1 | 4280397 | 1419 | 1.608 | 0.0579 | No | ||
| 9 | EIF2AK2 | 870239 | 1436 | 1.593 | 0.0678 | No | ||
| 10 | PDE6D | 3130537 3390014 | 1499 | 1.532 | 0.0749 | No | ||
| 11 | PSMB8 | 2850707 | 1560 | 1.473 | 0.0816 | No | ||
| 12 | C1QB | 5910292 | 1645 | 1.397 | 0.0866 | No | ||
| 13 | VSIG4 | 1580722 | 2141 | 1.012 | 0.0668 | No | ||
| 14 | AIF1 | 130332 5220017 | 2453 | 0.848 | 0.0557 | No | ||
| 15 | HCLS1 | 7100309 | 2608 | 0.756 | 0.0526 | No | ||
| 16 | IL10RB | 2900025 | 2891 | 0.622 | 0.0416 | No | ||
| 17 | POLR2A | 5220647 | 3043 | 0.556 | 0.0372 | No | ||
| 18 | CUGBP2 | 6180121 6840139 | 3053 | 0.553 | 0.0405 | No | ||
| 19 | GAPDH | 110022 430039 6220161 | 3637 | 0.342 | 0.0114 | No | ||
| 20 | LY86 | 2230093 | 4300 | 0.204 | -0.0230 | No | ||
| 21 | USP9X | 130435 2370735 3120338 | 5115 | 0.124 | -0.0660 | No | ||
| 22 | CD48 | 1570647 | 5228 | 0.117 | -0.0713 | No | ||
| 23 | LILRB4 | 630465 2940193 | 6358 | 0.066 | -0.1317 | No | ||
| 24 | GZMA | 3390315 | 6432 | 0.063 | -0.1352 | No | ||
| 25 | AOAH | 5390672 | 6510 | 0.060 | -0.1390 | No | ||
| 26 | FCER1G | 5550020 | 8984 | 0.010 | -0.2722 | No | ||
| 27 | CD163 | 2480315 | 9146 | 0.008 | -0.2809 | No | ||
| 28 | IFI30 | 730309 2940500 | 9446 | 0.004 | -0.2970 | No | ||
| 29 | RHOH | 130184 | 9467 | 0.003 | -0.2980 | No | ||
| 30 | MOXD1 | 2450301 | 10227 | -0.008 | -0.3389 | No | ||
| 31 | DARC | 3940050 | 11159 | -0.022 | -0.3890 | No | ||
| 32 | GBP2 | 50301 | 13014 | -0.067 | -0.4885 | No | ||
| 33 | COL6A3 | 2640717 4070064 5390717 | 13473 | -0.086 | -0.5126 | No | ||
| 34 | APOC1 | 5900066 6220408 | 14422 | -0.162 | -0.5626 | No | ||
| 35 | PRKCB1 | 870019 3130092 | 14833 | -0.221 | -0.5832 | No | ||
| 36 | TNFRSF1B | 3990035 5860372 | 14850 | -0.225 | -0.5826 | No | ||
| 37 | TYROBP | 2230020 | 15203 | -0.310 | -0.5995 | No | ||
| 38 | ALDOC | 450121 610427 | 15289 | -0.336 | -0.6018 | No | ||
| 39 | SFN | 6290301 7510608 | 15592 | -0.446 | -0.6150 | No | ||
| 40 | CFD | 2320736 | 15762 | -0.526 | -0.6206 | No | ||
| 41 | S100A4 | 3780113 | 15765 | -0.528 | -0.6171 | No | ||
| 42 | CD2 | 430672 | 15811 | -0.546 | -0.6158 | No | ||
| 43 | GLUL | 6040253 | 16173 | -0.752 | -0.6302 | No | ||
| 44 | IFITM1 | 1690601 3120438 6510075 | 16588 | -1.009 | -0.6456 | Yes | ||
| 45 | UBC | 1190129 1570161 5390079 6770097 7100500 | 16599 | -1.013 | -0.6393 | Yes | ||
| 46 | RAB27A | 450019 | 16627 | -1.025 | -0.6338 | Yes | ||
| 47 | RAC2 | 1580541 | 16776 | -1.151 | -0.6340 | Yes | ||
| 48 | LAPTM5 | 5550372 | 16941 | -1.289 | -0.6341 | Yes | ||
| 49 | UBE2L6 | 60048 1170687 | 17068 | -1.435 | -0.6311 | Yes | ||
| 50 | RASSF2 | 2480079 5720546 | 17340 | -1.774 | -0.6337 | Yes | ||
| 51 | WARS | 2570717 3290139 | 17342 | -1.777 | -0.6217 | Yes | ||
| 52 | PIM2 | 840136 5720692 7100577 | 17393 | -1.853 | -0.6118 | Yes | ||
| 53 | ITGB2 | 6380348 | 17422 | -1.900 | -0.6004 | Yes | ||
| 54 | DOCK2 | 2940040 | 17655 | -2.342 | -0.5970 | Yes | ||
| 55 | LCK | 3360142 | 17665 | -2.357 | -0.5815 | Yes | ||
| 56 | LST1 | 5420372 | 17746 | -2.516 | -0.5688 | Yes | ||
| 57 | STAT1 | 6510204 6590553 | 17835 | -2.706 | -0.5551 | Yes | ||
| 58 | SLA | 2000070 | 17846 | -2.731 | -0.5372 | Yes | ||
| 59 | CXCR4 | 4590519 | 17937 | -2.959 | -0.5219 | Yes | ||
| 60 | CD3D | 2810739 | 17940 | -2.964 | -0.5019 | Yes | ||
| 61 | MMP9 | 580338 | 18017 | -3.118 | -0.4848 | Yes | ||
| 62 | ISG20 | 1770750 | 18198 | -3.830 | -0.4686 | Yes | ||
| 63 | CD53 | 5550162 | 18221 | -3.932 | -0.4431 | Yes | ||
| 64 | LCN2 | 2510112 | 18244 | -4.082 | -0.4165 | Yes | ||
| 65 | CCND3 | 380528 730500 | 18358 | -4.702 | -0.3907 | Yes | ||
| 66 | INPP5D | 3450731 | 18474 | -5.772 | -0.3577 | Yes | ||
| 67 | IL4R | 2370520 | 18488 | -5.911 | -0.3183 | Yes | ||
| 68 | RGS10 | 2340292 | 18498 | -6.090 | -0.2775 | Yes | ||
| 69 | S100A8 | 70112 | 18510 | -6.250 | -0.2356 | Yes | ||
| 70 | GMFG | 1230142 6940242 | 18512 | -6.275 | -0.1931 | Yes | ||
| 71 | CD52 | 5910242 | 18519 | -6.411 | -0.1499 | Yes | ||
| 72 | IL10RA | 1770164 | 18530 | -6.591 | -0.1057 | Yes | ||
| 73 | CORO1A | 3140609 3190020 3190037 | 18574 | -7.823 | -0.0549 | Yes | ||
| 74 | CCL5 | 3710397 | 18593 | -8.422 | 0.0012 | Yes |
