Details for gene set BRENTANI

Table: GSEA Results Summary

Dataset	Set_03_wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy_repos
Phenotype	phenotype_wtNotch_versus_normalThy.cls#wtNotch_versus_normalThy_repos
Upregulated in class	normalThy
GeneSet	BRENTANI_SIGNALING
Enrichment Score (ES)	-0.6051976
Normalized Enrichment Score (NES)	-1.6307955
Nominal p-value	0.0
FDR q-value	0.19284374
FWER p-Value	0.785

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	MAP3K7IP1	2120095 5890452 6040167	296	3.632	0.0044	No
2	IL12RB1	2230338 5420053	494	2.962	0.0103	No
3	ITGA9	670180	567	2.758	0.0219	No
4	MAPKAPK2	2850500	616	2.672	0.0343	No
5	STAT5A	2680458	905	2.165	0.0309	No
6	IL10	2340685 2640541 2850403 6590286	1156	1.855	0.0277	No
7	JAK3	70347 3290008	1371	1.655	0.0254	No
8	TYK2	1660465 1740736	1410	1.615	0.0325	No
9	HRAS	1980551	1652	1.391	0.0272	No
10	MAPK13	6760215	1673	1.374	0.0338	No
11	CXCL1	2690537	1676	1.372	0.0414	No
12	SMO	5340538 6350132	1961	1.136	0.0324	No
13	JAG2	1500341	1984	1.116	0.0375	No
14	MYD88	2100717	1997	1.105	0.0431	No
15	ABL1	1050593 2030050 4010114	2011	1.099	0.0485	No
16	NOTCH3	3060603	2257	0.974	0.0407	No
17	TYRO3	3130193	2400	0.878	0.0380	No
18	STAT6	1190010 5720019	2499	0.821	0.0373	No
19	TNFSF13	2650170	2638	0.740	0.0339	No
20	ROCK1	130044	2909	0.612	0.0227	No
21	MAPK10	6110193	2956	0.591	0.0236	No
22	ITGB7	4670619	2972	0.586	0.0260	No
23	MAP2K4	5130133	2991	0.578	0.0283	No
24	NOTCH4	2450040 6370707	3068	0.549	0.0273	No
25	TNF	6650603	3118	0.530	0.0276	No
26	SUFU	6650181	3391	0.432	0.0153	No
27	ZAP70	1410494 2260504	3430	0.417	0.0156	No
28	TNFSF4	3940594	3733	0.312	0.0010	No
29	ITGA3	4570427	3889	0.278	-0.0059	No
30	ERG	50154 1770739	3890	0.277	-0.0043	No
31	REL	360707	3934	0.268	-0.0052	No
32	APC	3850484 5860722	4177	0.222	-0.0170	No
33	CAMK4	1690091	4340	0.200	-0.0247	No
34	IL1B	2640364	4401	0.191	-0.0269	No
35	WNT5A	840685 3120152	4412	0.189	-0.0263	No
36	BIRC2	2940435 4730020	4414	0.189	-0.0253	No
37	INHA	6100102	4481	0.181	-0.0279	No
38	MAP2K2	4590601	4513	0.178	-0.0286	No
39	TNFRSF10B	940671 1500451 6550768 6900500	4527	0.176	-0.0283	No
40	DLG1	2630091 6020286	4577	0.171	-0.0300	No
41	SOS1	7050338	4633	0.165	-0.0320	No
42	ITGB5	70129	4878	0.142	-0.0445	No
43	ITGA4	2470739	4938	0.137	-0.0469	No
44	MPL	2360253	4984	0.133	-0.0486	No
45	ILK	870601 4480180	5035	0.129	-0.0506	No
46	MAPK7	5670079 6100128	5225	0.117	-0.0601	No
47	TANK	1090020 2060458 2370400	5272	0.114	-0.0620	No
48	IL13	7040021	5273	0.114	-0.0614	No
49	MAPK11	130452 3120440 3610465	5405	0.107	-0.0679	No
50	WNT1	4780148	5578	0.098	-0.0766	No
51	GRB14	510035 3060369	5615	0.096	-0.0780	No
52	PTCH2	2900092	5669	0.093	-0.0804	No
53	CXCL2	610398	5670	0.093	-0.0799	No
54	MAP2K7	2260086	5781	0.087	-0.0853	No
55	MUSK	1190113	5809	0.086	-0.0863	No
56	MAS1	2650600	5858	0.084	-0.0884	No
57	RASA1	1240315	5862	0.084	-0.0881	No
58	ATM	3610110 4050524	6074	0.076	-0.0991	No
59	MCC	620750	6173	0.072	-0.1040	No
60	ITGAM	1190373	6378	0.065	-0.1147	No
61	ARHGAP6	2060121	7444	0.038	-0.1723	No
62	TTK	3800129	7453	0.038	-0.1725	No
63	RAN	2260446 4590647	7457	0.038	-0.1724	No
64	MAPKAPK5	2510601	7512	0.037	-0.1751	No
65	IGFBP3	2370500	7562	0.036	-0.1776	No
66	AKT1	5290746	7808	0.031	-0.1907	No
67	WNT4	4150619	7920	0.029	-0.1966	No
68	ARHGEF12	3990195	7937	0.029	-0.1973	No
69	IFNB1	1400142	8084	0.026	-0.2050	No
70	MAP2K1	840739	8442	0.019	-0.2243	No
71	NRAS	6900577	8445	0.019	-0.2243	No
72	CALM1	380128	8847	0.013	-0.2459	No
73	WNT2	4610020	9299	0.006	-0.2703	No
74	ARHGEF16	3990372	9503	0.003	-0.2813	No
75	NCK1	6200575 6510050	9651	0.001	-0.2893	No
76	SKIL	1090364	9741	-0.001	-0.2941	No
77	BTK	3130044	9841	-0.002	-0.2995	No
78	MAPK4	870142	9905	-0.003	-0.3029	No
79	YWHAE	5310435	10140	-0.006	-0.3155	No
80	IGFBP1	5720435	10363	-0.010	-0.3275	No
81	MAP3K12	2470373 6420162	10936	-0.019	-0.3584	No
82	SRC	580132	11142	-0.022	-0.3694	No
83	RAP1A	1090025	11445	-0.027	-0.3856	No
84	AKT2	3850541 3870519	11862	-0.036	-0.4079	No
85	MAP3K4	5720041	12130	-0.041	-0.4222	No
86	IRS1	1190204	12187	-0.043	-0.4250	No
87	ROS1	1090019	12216	-0.044	-0.4263	No
88	NF1	6980433	12559	-0.052	-0.4445	No
89	ABL2	580021	12686	-0.056	-0.4510	No
90	JAG1	3440390	12840	-0.061	-0.4590	No
91	IFNG	5670592	13106	-0.070	-0.4729	No
92	ITGAX	6130524	13264	-0.077	-0.4810	No
93	IL15	4560332 5860438	13419	-0.084	-0.4889	No
94	ITGAE	4210632 4670239 5340253 5420746 5690154 5700685 6770154	13771	-0.104	-0.5073	No
95	SYK	6940133	13785	-0.106	-0.5074	No
96	PTPRK	1450433 2640142	13803	-0.106	-0.5078	No
97	MAP3K5	6020041 6380162	13822	-0.108	-0.5081	No
98	CXCL12	580546 4150750 4570068	13854	-0.110	-0.5092	No
99	IFNAR1	4730672	13977	-0.119	-0.5151	No
100	ITGA7	1230739	13987	-0.120	-0.5150	No
101	SHC1	2900731 3170504 6520537	14198	-0.138	-0.5256	No
102	MAP2K3	5570193	14571	-0.175	-0.5447	No
103	STAT5B	6200026	14806	-0.214	-0.5562	No
104	MAPK12	450022 1340717 7050484	14849	-0.225	-0.5572	No
105	TNFRSF1B	3990035 5860372	14850	-0.225	-0.5560	No
106	MAPK1	3190193 6200253	14867	-0.227	-0.5556	No
107	VIPR1	2480292 5720288 6760537	14937	-0.244	-0.5579	No
108	BCR	2260020 4230180 6040195	15064	-0.272	-0.5632	No
109	ITGB3	5270463	15112	-0.281	-0.5642	No
110	ITGAV	2340020	15144	-0.288	-0.5643	No
111	ARHGAP1	2810010 5270064	15228	-0.319	-0.5670	No
112	ITGA5	5550520	15396	-0.367	-0.5740	No
113	IKBKG	3450092 3840377 6590592	15419	-0.375	-0.5730	No
114	SFN	6290301 7510608	15592	-0.446	-0.5799	No
115	ITGB4	1740021 3840482	15601	-0.449	-0.5778	No
116	IL18R1	270546	15684	-0.491	-0.5795	No
117	GRB7	2100471	16160	-0.742	-0.6010	Yes
118	MAP2K5	2030440	16192	-0.764	-0.5984	Yes
119	MAP3K8	2940286	16231	-0.789	-0.5960	Yes
120	JAK1	5910746	16259	-0.809	-0.5930	Yes
121	ITGB1	5080156 6270528	16264	-0.811	-0.5886	Yes
122	FYN	2100468 4760520 4850687	16323	-0.850	-0.5870	Yes
123	CRK	1230162 4780128	16534	-0.989	-0.5928	Yes
124	MAPK9	2060273 3780209 4070397	16570	-1.002	-0.5891	Yes
125	PIK3CG	5890110	16778	-1.152	-0.5938	Yes
126	IFNAR2	4070687 7100484	16796	-1.165	-0.5882	Yes
127	RALBP1	4780632	16852	-1.205	-0.5844	Yes
128	PTEN	3390064	16854	-1.207	-0.5777	Yes
129	IL2RB	4730072	16881	-1.233	-0.5722	Yes
130	PIK3C3	6590717	16982	-1.326	-0.5702	Yes
131	RGS16	780091	16984	-1.327	-0.5628	Yes
132	MAP4K4	2360059	17112	-1.492	-0.5613	Yes
133	TRAF6	4810292 6200132	17171	-1.553	-0.5557	Yes
134	RELA	3830075	17220	-1.623	-0.5492	Yes
135	RAF1	1770600	17237	-1.646	-0.5408	Yes
136	MAP3K14	5890435	17267	-1.682	-0.5329	Yes
137	RELB	1400048	17302	-1.724	-0.5251	Yes
138	AXIN2	3850131	17407	-1.881	-0.5201	Yes
139	ITGB2	6380348	17422	-1.900	-0.5102	Yes
140	TNFRSF4	6840056	17487	-2.012	-0.5024	Yes
141	DGKA	5720152 5890328	17539	-2.106	-0.4933	Yes
142	MKNK1	6510161	17575	-2.159	-0.4831	Yes
143	AXL	1770095	17625	-2.273	-0.4730	Yes
144	STAT2	3780519	17691	-2.398	-0.4630	Yes
145	SH3BP2	610131	17723	-2.463	-0.4509	Yes
146	ITGA6	3830129	17737	-2.489	-0.4376	Yes
147	STAT1	6510204 6590553	17835	-2.706	-0.4276	Yes
148	AXIN1	3360358 6940451	17852	-2.743	-0.4131	Yes
149	MAP2K6	1230056 2940204	17854	-2.745	-0.3977	Yes
150	VAV1	6020487	17923	-2.904	-0.3851	Yes
151	IL6ST	5890047	17936	-2.959	-0.3691	Yes
152	ITGAL	1450324	17984	-3.043	-0.3546	Yes
153	GNB1	2120397	18005	-3.100	-0.3383	Yes
154	BCL10	2360397	18036	-3.190	-0.3220	Yes
155	TNFRSF14	5050438	18038	-3.207	-0.3040	Yes
156	TIAM1	5420288	18120	-3.517	-0.2886	Yes
157	DGKQ	2480609	18163	-3.687	-0.2702	Yes
158	STAT3	460040 3710341	18169	-3.701	-0.2497	Yes
159	CRKL	4050427	18209	-3.866	-0.2301	Yes
160	TRAF1	3440735	18283	-4.285	-0.2100	Yes
161	PDPK1	6650168	18323	-4.496	-0.1868	Yes
162	MAP3K3	610685	18366	-4.757	-0.1624	Yes
163	IFNGR1	610577	18382	-4.889	-0.1357	Yes
164	TRAF3	5690647	18422	-5.287	-0.1081	Yes
165	DGKG	1770025	18513	-6.335	-0.0774	Yes
166	PTK2B	4730411	18521	-6.456	-0.0415	Yes
167	TNFRSF1A	1090390 6520735	18584	-8.303	0.0017	Yes