Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_03_wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy_repos |
| Phenotype | phenotype_wtNotch_versus_normalThy.cls#wtNotch_versus_normalThy_repos |
| Upregulated in class | normalThy |
| GeneSet | BLEO_HUMAN_LYMPH_HIGH_24HRS_UP |
| Enrichment Score (ES) | -0.65207046 |
| Normalized Enrichment Score (NES) | -1.5770682 |
| Nominal p-value | 0.0017985612 |
| FDR q-value | 0.27397138 |
| FWER p-Value | 0.986 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | MRPL49 | 460541 610162 5340156 | 22 | 7.249 | 0.0515 | No | ||
| 2 | GCH1 | 670364 6550358 | 591 | 2.707 | 0.0405 | No | ||
| 3 | EI24 | 3120433 | 781 | 2.381 | 0.0476 | No | ||
| 4 | RPS6KA1 | 4120647 | 789 | 2.372 | 0.0644 | No | ||
| 5 | CDKN1A | 4050088 6400706 | 809 | 2.336 | 0.0803 | No | ||
| 6 | TAX1BP3 | 940706 6100687 6220176 | 1274 | 1.737 | 0.0679 | No | ||
| 7 | ICAM1 | 6980138 | 1614 | 1.420 | 0.0600 | No | ||
| 8 | ENC1 | 4810348 | 2015 | 1.097 | 0.0463 | No | ||
| 9 | PKIG | 2030300 5260255 | 2178 | 0.999 | 0.0449 | No | ||
| 10 | LPXN | 2360142 | 2596 | 0.762 | 0.0279 | No | ||
| 11 | HCLS1 | 7100309 | 2608 | 0.756 | 0.0328 | No | ||
| 12 | RUNX3 | 3800546 | 2976 | 0.583 | 0.0172 | No | ||
| 13 | CCL4 | 50368 430047 | 3297 | 0.460 | 0.0033 | No | ||
| 14 | CAPN1 | 6660300 | 3357 | 0.444 | 0.0033 | No | ||
| 15 | MYO5A | 2900288 5270333 | 3372 | 0.440 | 0.0058 | No | ||
| 16 | ACTA2 | 60008 1230082 | 3624 | 0.345 | -0.0053 | No | ||
| 17 | FAS | 4480112 6110040 | 3651 | 0.337 | -0.0042 | No | ||
| 18 | ZFP36L2 | 510180 | 3995 | 0.253 | -0.0209 | No | ||
| 19 | DUSP14 | 1230358 | 4071 | 0.240 | -0.0232 | No | ||
| 20 | CRYZ | 1770110 2360484 4810541 | 4246 | 0.211 | -0.0310 | No | ||
| 21 | TNFRSF10B | 940671 1500451 6550768 6900500 | 4527 | 0.176 | -0.0449 | No | ||
| 22 | AIM1 | 2810142 | 4809 | 0.148 | -0.0589 | No | ||
| 23 | GDF15 | 4730017 | 4905 | 0.140 | -0.0631 | No | ||
| 24 | CCL2 | 4760019 | 5083 | 0.126 | -0.0717 | No | ||
| 25 | TANK | 1090020 2060458 2370400 | 5272 | 0.114 | -0.0810 | No | ||
| 26 | FDXR | 2100576 5910528 | 5349 | 0.110 | -0.0843 | No | ||
| 27 | FUCA1 | 610075 | 5356 | 0.110 | -0.0838 | No | ||
| 28 | ADAM8 | 450347 5670609 | 5999 | 0.079 | -0.1179 | No | ||
| 29 | SMTN | 670563 1190438 | 6036 | 0.077 | -0.1193 | No | ||
| 30 | PLEK | 1090039 | 7443 | 0.038 | -0.1948 | No | ||
| 31 | PTP4A1 | 130692 | 8497 | 0.019 | -0.2515 | No | ||
| 32 | NCF2 | 540129 2370441 2650133 | 9602 | 0.001 | -0.3111 | No | ||
| 33 | CFLAR | 2320605 6180440 | 10426 | -0.011 | -0.3554 | No | ||
| 34 | HIF1A | 5670605 | 10446 | -0.011 | -0.3563 | No | ||
| 35 | CCNG1 | 870402 1500685 6110594 | 10821 | -0.017 | -0.3764 | No | ||
| 36 | XPC | 6370193 | 12117 | -0.041 | -0.4459 | No | ||
| 37 | PMAIP1 | 1400717 5360047 5900039 | 12878 | -0.062 | -0.4865 | No | ||
| 38 | BASP1 | 5700044 | 13523 | -0.089 | -0.5206 | No | ||
| 39 | MS4A1 | 4210598 | 13720 | -0.101 | -0.5304 | No | ||
| 40 | DDB2 | 3520341 4610168 4850184 4920717 | 13864 | -0.111 | -0.5373 | No | ||
| 41 | BIRC3 | 6550411 | 14074 | -0.127 | -0.5477 | No | ||
| 42 | CTSH | 60524 | 14270 | -0.146 | -0.5572 | No | ||
| 43 | BTG2 | 2350411 | 14579 | -0.176 | -0.5725 | No | ||
| 44 | ANXA4 | 1400315 | 14834 | -0.221 | -0.5846 | No | ||
| 45 | CCR1 | 3440672 | 14906 | -0.236 | -0.5867 | No | ||
| 46 | TNFSF9 | 1190408 | 14909 | -0.237 | -0.5851 | No | ||
| 47 | SH3BP5 | 7100408 | 15208 | -0.312 | -0.5989 | No | ||
| 48 | LTA | 1740088 | 15617 | -0.457 | -0.6176 | No | ||
| 49 | CD40 | 2760471 2940390 6220402 6220452 | 15955 | -0.631 | -0.6312 | No | ||
| 50 | VASP | 7050500 | 16343 | -0.863 | -0.6458 | Yes | ||
| 51 | MARCKS | 7040450 | 16376 | -0.885 | -0.6411 | Yes | ||
| 52 | RAD51C | 3780592 | 16451 | -0.931 | -0.6383 | Yes | ||
| 53 | TNFRSF9 | 2510400 6650484 | 16498 | -0.960 | -0.6338 | Yes | ||
| 54 | LRMP | 6290193 | 16726 | -1.108 | -0.6380 | Yes | ||
| 55 | GPX1 | 4150093 | 16775 | -1.150 | -0.6323 | Yes | ||
| 56 | LAPTM5 | 5550372 | 16941 | -1.289 | -0.6318 | Yes | ||
| 57 | RGS16 | 780091 | 16984 | -1.327 | -0.6245 | Yes | ||
| 58 | NFKB2 | 2320670 | 17059 | -1.421 | -0.6181 | Yes | ||
| 59 | SOX4 | 2260091 | 17066 | -1.434 | -0.6080 | Yes | ||
| 60 | TUSC2 | 1580253 | 17089 | -1.460 | -0.5986 | Yes | ||
| 61 | PRKAR1A | 3450369 | 17347 | -1.790 | -0.5995 | Yes | ||
| 62 | PPM1D | 1690193 | 17389 | -1.847 | -0.5883 | Yes | ||
| 63 | PIM2 | 840136 5720692 7100577 | 17393 | -1.853 | -0.5750 | Yes | ||
| 64 | DUSP2 | 2370184 | 17558 | -2.134 | -0.5683 | Yes | ||
| 65 | NCOA3 | 4540195 | 17726 | -2.466 | -0.5594 | Yes | ||
| 66 | PRKAB1 | 7050403 | 17955 | -2.981 | -0.5501 | Yes | ||
| 67 | CD83 | 4150242 | 18016 | -3.118 | -0.5307 | Yes | ||
| 68 | NFKBIA | 1570152 | 18160 | -3.680 | -0.5117 | Yes | ||
| 69 | STAT3 | 460040 3710341 | 18169 | -3.701 | -0.4852 | Yes | ||
| 70 | BRD2 | 1450300 5340484 6100605 | 18266 | -4.192 | -0.4600 | Yes | ||
| 71 | TRAF1 | 3440735 | 18283 | -4.285 | -0.4297 | Yes | ||
| 72 | GADD45A | 2900717 | 18319 | -4.477 | -0.3991 | Yes | ||
| 73 | PLD3 | 510041 | 18412 | -5.170 | -0.3665 | Yes | ||
| 74 | CYFIP2 | 520577 6040300 | 18449 | -5.552 | -0.3282 | Yes | ||
| 75 | SORL1 | 630204 | 18493 | -5.965 | -0.2872 | Yes | ||
| 76 | WDR1 | 1090129 3990121 | 18543 | -6.863 | -0.2400 | Yes | ||
| 77 | TNFAIP3 | 2900142 | 18562 | -7.402 | -0.1872 | Yes | ||
| 78 | CCND2 | 5340167 | 18589 | -8.378 | -0.1278 | Yes | ||
| 79 | CCL5 | 3710397 | 18593 | -8.422 | -0.0668 | Yes | ||
| 80 | BTG1 | 4200735 6040131 6200133 | 18614 | -9.359 | 0.0001 | Yes |
