Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_03_wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy_repos |
| Phenotype | phenotype_wtNotch_versus_normalThy.cls#wtNotch_versus_normalThy_repos |
| Upregulated in class | normalThy |
| GeneSet | REACTOME_TCR_SIGNALING |
| Enrichment Score (ES) | -0.77809566 |
| Normalized Enrichment Score (NES) | -1.6672158 |
| Nominal p-value | 0.0018050541 |
| FDR q-value | 0.04013232 |
| FWER p-Value | 0.295 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | PTPRC | 130402 5290148 | 1316 | 1.706 | -0.0383 | No | ||
| 2 | NFKB1 | 5420358 | 2322 | 0.926 | -0.0748 | No | ||
| 3 | MAP3K7 | 6040068 | 2753 | 0.679 | -0.0850 | No | ||
| 4 | ZAP70 | 1410494 2260504 | 3430 | 0.417 | -0.1134 | No | ||
| 5 | UBE2N | 520369 2900047 | 4546 | 0.174 | -0.1701 | No | ||
| 6 | ENAH | 1690292 5700300 | 4552 | 0.174 | -0.1670 | No | ||
| 7 | RIPK2 | 5050072 6290632 | 5335 | 0.111 | -0.2070 | No | ||
| 8 | GRAP2 | 7100441 1410647 | 6376 | 0.065 | -0.2617 | No | ||
| 9 | PIK3R1 | 4730671 | 7165 | 0.043 | -0.3033 | No | ||
| 10 | PRKCQ | 2260170 3870193 | 9201 | 0.007 | -0.4127 | No | ||
| 11 | NCK1 | 6200575 6510050 | 9651 | 0.001 | -0.4368 | No | ||
| 12 | CHUK | 7050736 | 11886 | -0.036 | -0.5563 | No | ||
| 13 | PLCG1 | 6020369 | 12826 | -0.060 | -0.6057 | No | ||
| 14 | PAK1 | 4540315 | 13219 | -0.075 | -0.6254 | No | ||
| 15 | IKBKB | 6840072 | 15462 | -0.391 | -0.7386 | No | ||
| 16 | LCP2 | 2680066 6650707 | 16159 | -0.742 | -0.7619 | Yes | ||
| 17 | WAS | 5270193 | 16461 | -0.938 | -0.7602 | Yes | ||
| 18 | CSK | 6350593 | 16555 | -0.997 | -0.7463 | Yes | ||
| 19 | PIK3CB | 3800600 | 16603 | -1.014 | -0.7295 | Yes | ||
| 20 | LAT | 3170025 | 16642 | -1.039 | -0.7117 | Yes | ||
| 21 | FYB | 1690440 | 16760 | -1.136 | -0.6964 | Yes | ||
| 22 | PTEN | 3390064 | 16854 | -1.207 | -0.6784 | Yes | ||
| 23 | RELA | 3830075 | 17220 | -1.623 | -0.6671 | Yes | ||
| 24 | LCK | 3360142 | 17665 | -2.357 | -0.6461 | Yes | ||
| 25 | CD3D | 2810739 | 17940 | -2.964 | -0.6044 | Yes | ||
| 26 | BCL10 | 2360397 | 18036 | -3.190 | -0.5488 | Yes | ||
| 27 | NFKBIA | 1570152 | 18160 | -3.680 | -0.4853 | Yes | ||
| 28 | CD4 | 1090010 | 18200 | -3.836 | -0.4144 | Yes | ||
| 29 | PDPK1 | 6650168 | 18323 | -4.496 | -0.3353 | Yes | ||
| 30 | CD3E | 3800056 | 18384 | -4.904 | -0.2452 | Yes | ||
| 31 | CD3G | 2680288 | 18515 | -6.372 | -0.1308 | Yes | ||
| 32 | ITK | 2230592 | 18551 | -7.151 | 0.0035 | Yes |
