Details for gene set REACTOME_SIGNALING_BY

Table: GSEA Results Summary

Dataset	Set_03_wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy_repos
Phenotype	phenotype_wtNotch_versus_normalThy.cls#wtNotch_versus_normalThy_repos
Upregulated in class	normalThy
GeneSet	REACTOME_SIGNALING_BY_GPCR
Enrichment Score (ES)	-0.6191301
Normalized Enrichment Score (NES)	-1.6389548
Nominal p-value	0.0
FDR q-value	0.06859014
FWER p-Value	0.495

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	CNR2	2760398	600	2.694	0.0014	No
2	F2	5720280	852	2.255	0.0162	No
3	P2RY6	5290400	1610	1.422	-0.0069	No
4	GAL	3930279	1828	1.246	-0.0029	No
5	P2RY10	6370039 6840204	2410	0.875	-0.0234	No
6	P2RY2	2640180 2810128	2759	0.674	-0.0337	No
7	GPR17	5890671	2770	0.670	-0.0258	No
8	ROCK1	130044	2909	0.612	-0.0256	No
9	CCL25	450541 540435	3111	0.533	-0.0298	No
10	ADCY6	450364 6290670 6940286	3129	0.525	-0.0241	No
11	HRH2	3840440	3131	0.524	-0.0176	No
12	SCTR	2940070	3575	0.367	-0.0369	No
13	LTB4R	1770056	3804	0.298	-0.0455	No
14	PDE4D	2470528 6660014	3848	0.288	-0.0442	No
15	NTSR1	6510136	3923	0.271	-0.0448	No
16	PDYN	5720408	3935	0.268	-0.0420	No
17	PNOC	1990114	4179	0.222	-0.0524	No
18	OPN1SW	6420377	4593	0.169	-0.0726	No
19	AVP	2100113	4724	0.156	-0.0777	No
20	GRK5	1940348 4670053	4902	0.140	-0.0855	No
21	AVPR1A	2120300	4928	0.138	-0.0851	No
22	ADCYAP1	520086	4988	0.132	-0.0867	No
23	GCG	6220735	5111	0.125	-0.0917	No
24	ADRA1D	380035 540025	5238	0.116	-0.0971	No
25	PTGER2	3170039	5288	0.114	-0.0983	No
26	PLCB2	360132	5366	0.109	-0.1011	No
27	IAPP	4230040	5409	0.107	-0.1020	No
28	GNA14	3390017	5504	0.101	-0.1058	No
29	SSTR1	2630471	5628	0.096	-0.1113	No
30	KISS1	1580398	5834	0.085	-0.1213	No
31	GALR1	6020452	6020	0.078	-0.1303	No
32	MC2R	2970504	6038	0.077	-0.1303	No
33	PTGER3	2900739 6770750	6096	0.075	-0.1324	No
34	CGB	580273	6250	0.069	-0.1398	No
35	NTS	380300 2120592	6276	0.068	-0.1403	No
36	IL8RB	450592 1170537	6360	0.066	-0.1440	No
37	CASR	610504	6393	0.064	-0.1449	No
38	TSHR	1190687 5270364	6424	0.063	-0.1457	No
39	CCK	6370368	6922	0.049	-0.1720	No
40	CCR3	50427	6932	0.049	-0.1719	No
41	CXCL11	1090551	6946	0.049	-0.1720	No
42	HCRTR2	2350463	7144	0.044	-0.1821	No
43	PIK3R1	4730671	7165	0.043	-0.1826	No
44	TACR3	4780017	7168	0.043	-0.1822	No
45	MTNR1A	380204	7306	0.041	-0.1891	No
46	TACR2	1740358	7309	0.041	-0.1887	No
47	HTR1F	670148	7319	0.040	-0.1887	No
48	LHCGR	4560465 5860551	7378	0.039	-0.1913	No
49	DRD1	430025	7409	0.039	-0.1925	No
50	VIP	2850647	7468	0.037	-0.1951	No
51	PPY	2340373	7556	0.036	-0.1994	No
52	GLP2R	4150577 5290273 7050095	7573	0.035	-0.1998	No
53	AKT1	5290746	7808	0.031	-0.2121	No
54	SST	6590142	8046	0.027	-0.2246	No
55	HCRT	2970463	8060	0.026	-0.2249	No
56	ADM2	4060102	8072	0.026	-0.2252	No
57	CCKBR	2760128	8161	0.024	-0.2297	No
58	C5AR1	4540402	8229	0.023	-0.2330	No
59	GLP1R	6420528	8317	0.022	-0.2374	No
60	EDNRA	6900133	8319	0.022	-0.2372	No
61	GNAT1	5270048 6100170	8381	0.021	-0.2403	No
62	GRPR	6020170	8427	0.020	-0.2424	No
63	ADRA2A	5340520	8443	0.019	-0.2430	No
64	PPYR1	1410072	8548	0.018	-0.2484	No
65	VIPR2	6520050	8628	0.016	-0.2525	No
66	GNAZ	6130296	8655	0.016	-0.2537	No
67	GPRC6A	4560576	8758	0.014	-0.2590	No
68	GHRHR	3130500 4010154	8910	0.012	-0.2671	No
69	PTGER1	6100132	9084	0.009	-0.2763	No
70	PTGFR	3850373	9145	0.008	-0.2795	No
71	OXT	3850692	9269	0.006	-0.2860	No
72	GHRH	4570575	9361	0.005	-0.2909	No
73	BAI3	940692	9500	0.003	-0.2983	No
74	ADORA1	6370520	9664	0.000	-0.3071	No
75	GIP	3170364	9670	0.000	-0.3074	No
76	EDN1	1770047	9776	-0.001	-0.3131	No
77	PIK3CA	6220129	9883	-0.003	-0.3188	No
78	ADCYAP1R1	3390020 4280184 5360180	10115	-0.006	-0.3312	No
79	HTR6	4850022	10205	-0.007	-0.3359	No
80	P2RY4	630053	10528	-0.012	-0.3532	No
81	CRH	3710301	10541	-0.012	-0.3537	No
82	HRH1	840100	10576	-0.013	-0.3554	No
83	CALCA	5860167	10676	-0.015	-0.3606	No
84	CCR10	4050097	10819	-0.017	-0.3680	No
85	GNGT1	5220156	11089	-0.021	-0.3823	No
86	DARC	3940050	11159	-0.022	-0.3858	No
87	TACR1	70358 3840411	11256	-0.024	-0.3907	No
88	IL8RA	1580100	11347	-0.026	-0.3952	No
89	CHRM5	5390333	11392	-0.027	-0.3973	No
90	CHRM2	870750	11399	-0.027	-0.3973	No
91	KNG1	6400576 6770347	11477	-0.028	-0.4011	No
92	DRD3	4780402	11577	-0.030	-0.4061	No
93	TAC1	7000195 380706	11613	-0.030	-0.4076	No
94	GCGR	6620497	11625	-0.031	-0.4078	No
95	LHB	1450368	11638	-0.031	-0.4080	No
96	HCRTR1	1580273	11670	-0.031	-0.4093	No
97	AGTR1	4780524 2680592	11674	-0.031	-0.4091	No
98	CALCR	1690494	12290	-0.045	-0.4418	No
99	FSHR	610041 7040121	12317	-0.046	-0.4426	No
100	CGA	630403	12441	-0.048	-0.4487	No
101	CXCR6	3190440	12460	-0.049	-0.4490	No
102	TSHB	6770500	12756	-0.058	-0.4643	No
103	XCR1	5080072	12839	-0.061	-0.4680	No
104	PTGDR	3850161	13104	-0.070	-0.4814	No
105	FSHB	7100592	13233	-0.075	-0.4874	No
106	AGT	7000575	13253	-0.076	-0.4874	No
107	MC5R	2640176	13519	-0.089	-0.5007	No
108	NPFF	2030280	13567	-0.091	-0.5021	No
109	BDKRB1	730592	13933	-0.115	-0.5204	No
110	OPRM1	5360279	13964	-0.118	-0.5205	No
111	P2RY1	6040121	14139	-0.133	-0.5283	No
112	CRHR2	4590672	14144	-0.134	-0.5268	No
113	ADORA2A	1990687	14147	-0.134	-0.5252	No
114	CALCRL	4280035	14365	-0.155	-0.5350	No
115	CCR6	5720368 6020176	14371	-0.156	-0.5333	No
116	GRM6	2030398	14384	-0.157	-0.5320	No
117	CX3CL1	3990707	14550	-0.173	-0.5387	No
118	GNAQ	430670 4210131 5900736	14693	-0.195	-0.5440	No
119	AVPR2	360064	14963	-0.250	-0.5554	No
120	GNA12	1230301	15157	-0.292	-0.5622	No
121	HTR2A	360037 6330255	15252	-0.327	-0.5631	No
122	SCT	2230348	15459	-0.388	-0.5694	No
123	P2RY14	6100497	16180	-0.758	-0.5988	No
124	GNAS	630441 1850373 4050152	16556	-0.998	-0.6066	Yes
125	GNA13	4590102	16772	-1.147	-0.6038	Yes
126	PIK3CG	5890110	16778	-1.152	-0.5896	Yes
127	NMB	3360735	16942	-1.289	-0.5822	Yes
128	ADRBK1	1340333	17027	-1.377	-0.5694	Yes
129	PTGIR	2100563	17132	-1.521	-0.5559	Yes
130	RHOA	580142 5900131 5340450	17313	-1.730	-0.5439	Yes
131	RHOG	6760575	17437	-1.919	-0.5264	Yes
132	F2R	4810180	17732	-2.480	-0.5111	Yes
133	RAMP1	2320168	17760	-2.546	-0.4805	Yes
134	GNG2	2230390	17790	-2.614	-0.4492	Yes
135	GNB1	2120397	18005	-3.100	-0.4218	Yes
136	ADRB2	3290373	18009	-3.105	-0.3829	Yes
137	PDPK1	6650168	18323	-4.496	-0.3433	Yes
138	TBXA2R	2370292 3940066	18518	-6.411	-0.2731	Yes
139	XCL1	3800504	18523	-6.528	-0.1912	Yes
140	CCR7	2060687	18554	-7.168	-0.1026	Yes
141	CCL5	3710397	18593	-8.422	0.0012	Yes