Dataset | Set_03_wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy_repos |
Phenotype | phenotype_wtNotch_versus_normalThy.cls#wtNotch_versus_normalThy_repos |
Upregulated in class | wtNotch |
GeneSet | REACTOME_METABOLISM_OF_PROTEINS |
Enrichment Score (ES) | 0.66519064 |
Normalized Enrichment Score (NES) | 1.7798789 |
Nominal p-value | 0.0 |
FDR q-value | 0.0024217637 |
FWER p-Value | 0.022 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | EIF2B5 | 430315 6900400 | 10 | 8.726 | 0.0776 | Yes | ||
2 | EIF2S2 | 770095 2810487 | 116 | 4.607 | 0.1132 | Yes | ||
3 | RPS19 | 5860066 | 163 | 4.257 | 0.1488 | Yes | ||
4 | RPS3A | 2470086 | 188 | 4.101 | 0.1843 | Yes | ||
5 | CCT6A | 2350368 | 221 | 3.944 | 0.2178 | Yes | ||
6 | CCT3 | 7100403 | 319 | 3.535 | 0.2443 | Yes | ||
7 | RPL38 | 70040 4060138 6200601 | 472 | 3.001 | 0.2629 | Yes | ||
8 | RPS24 | 5420377 | 487 | 2.973 | 0.2888 | Yes | ||
9 | ETF1 | 6770075 | 582 | 2.725 | 0.3081 | Yes | ||
10 | RPL30 | 4810369 | 617 | 2.672 | 0.3302 | Yes | ||
11 | EIF2B1 | 4610082 7040242 | 624 | 2.662 | 0.3537 | Yes | ||
12 | EIF4B | 5390563 5270577 | 653 | 2.610 | 0.3756 | Yes | ||
13 | ACTB | 1660736 2030204 2060215 5050047 | 665 | 2.589 | 0.3982 | Yes | ||
14 | EEF1D | 2320524 2510341 | 701 | 2.532 | 0.4190 | Yes | ||
15 | CCT4 | 6380161 | 788 | 2.374 | 0.4356 | Yes | ||
16 | PFDN6 | 4150519 | 837 | 2.284 | 0.4534 | Yes | ||
17 | F2 | 5720280 | 852 | 2.255 | 0.4729 | Yes | ||
18 | GPAA1 | 1500463 | 873 | 2.228 | 0.4917 | Yes | ||
19 | TBCA | 6400095 | 954 | 2.095 | 0.5062 | Yes | ||
20 | VBP1 | 4070050 | 989 | 2.057 | 0.5228 | Yes | ||
21 | CCT2 | 1690113 | 1096 | 1.916 | 0.5342 | Yes | ||
22 | CCT5 | 1050670 | 1142 | 1.862 | 0.5484 | Yes | ||
23 | CCT8 | 6220019 | 1198 | 1.818 | 0.5617 | Yes | ||
24 | DHPS | 5340735 | 1287 | 1.730 | 0.5725 | Yes | ||
25 | EIF4A1 | 1990341 2810300 | 1458 | 1.576 | 0.5774 | Yes | ||
26 | EIF2B2 | 4290048 | 1464 | 1.570 | 0.5912 | Yes | ||
27 | F10 | 3830450 | 1615 | 1.418 | 0.5958 | Yes | ||
28 | EIF4G1 | 4070446 | 1619 | 1.417 | 0.6083 | Yes | ||
29 | RPS4X | 2690020 | 1689 | 1.364 | 0.6168 | Yes | ||
30 | RPS23 | 7100594 | 1727 | 1.325 | 0.6267 | Yes | ||
31 | RPS15A | 1170180 | 1753 | 1.302 | 0.6370 | Yes | ||
32 | RPL14 | 5080471 | 1809 | 1.261 | 0.6453 | Yes | ||
33 | PLAUR | 5910280 | 2096 | 1.040 | 0.6392 | Yes | ||
34 | PABPC1 | 2650180 2690253 6020632 1990270 | 2171 | 1.000 | 0.6441 | Yes | ||
35 | EEF1G | 3940603 | 2397 | 0.882 | 0.6399 | Yes | ||
36 | GAS6 | 4480021 | 2409 | 0.876 | 0.6471 | Yes | ||
37 | RPS3 | 1570017 2370170 | 2477 | 0.834 | 0.6510 | Yes | ||
38 | DPM2 | 3610253 | 2563 | 0.781 | 0.6534 | Yes | ||
39 | F7 | 5080411 | 2616 | 0.749 | 0.6573 | Yes | ||
40 | RPL5 | 840095 | 2661 | 0.732 | 0.6615 | Yes | ||
41 | RPS2 | 1340647 | 2710 | 0.706 | 0.6652 | Yes | ||
42 | RPL37A | 7040717 | 3104 | 0.537 | 0.6488 | No | ||
43 | RPL4 | 2940014 5420324 | 3232 | 0.487 | 0.6463 | No | ||
44 | RPL18A | 4570619 | 3238 | 0.485 | 0.6503 | No | ||
45 | RPS13 | 1570364 | 3334 | 0.448 | 0.6492 | No | ||
46 | GGCX | 770377 3990441 | 3339 | 0.447 | 0.6530 | No | ||
47 | RPS17 | 2360528 | 3711 | 0.320 | 0.6359 | No | ||
48 | RPL27A | 3130451 110195 6840494 | 3767 | 0.304 | 0.6356 | No | ||
49 | DPM1 | 1240050 4810019 6380398 | 4293 | 0.206 | 0.6091 | No | ||
50 | EIF2S1 | 5360292 | 4415 | 0.189 | 0.6043 | No | ||
51 | RPSA | 2360408 2680736 | 5191 | 0.119 | 0.5635 | No | ||
52 | PROC | 6520270 | 5596 | 0.097 | 0.5425 | No | ||
53 | PIGW | 4810072 | 6375 | 0.065 | 0.5011 | No | ||
54 | RPL41 | 6940112 | 7639 | 0.034 | 0.4332 | No | ||
55 | PROZ | 3440541 | 7685 | 0.033 | 0.4311 | No | ||
56 | RPL17 | 2690167 5690504 | 7836 | 0.031 | 0.4233 | No | ||
57 | PFDN1 | 7000095 | 7984 | 0.028 | 0.4156 | No | ||
58 | PIGP | 4280204 5890440 | 8864 | 0.012 | 0.3682 | No | ||
59 | PIGN | 4210736 | 9005 | 0.010 | 0.3607 | No | ||
60 | F9 | 3190154 | 9644 | 0.001 | 0.3263 | No | ||
61 | TBCE | 520692 | 10352 | -0.009 | 0.2882 | No | ||
62 | EIF5B | 1190102 4200440 | 11195 | -0.023 | 0.2429 | No | ||
63 | SEMA6D | 4050324 5860138 6350307 | 12780 | -0.059 | 0.1579 | No | ||
64 | RPS21 | 3120673 | 13047 | -0.068 | 0.1442 | No | ||
65 | RPL27 | 1940088 | 13280 | -0.078 | 0.1323 | No | ||
66 | EIF5 | 6380750 | 13457 | -0.086 | 0.1236 | No | ||
67 | EEF2 | 1050369 4670035 5890598 | 13557 | -0.090 | 0.1191 | No | ||
68 | PIGF | 5690050 | 13830 | -0.108 | 0.1054 | No | ||
69 | RPL18 | 6380181 3870195 | 13885 | -0.112 | 0.1034 | No | ||
70 | RPL37 | 3170494 3870750 4280494 | 13891 | -0.113 | 0.1042 | No | ||
71 | RPS28 | 3830221 | 13919 | -0.114 | 0.1038 | No | ||
72 | RPS15 | 580100 | 14572 | -0.175 | 0.0701 | No | ||
73 | RPLP2 | 5290020 | 14619 | -0.184 | 0.0693 | No | ||
74 | RPS20 | 1740092 | 14776 | -0.209 | 0.0627 | No | ||
75 | RPL39 | 2370446 | 14790 | -0.211 | 0.0639 | No | ||
76 | RPL35A | 2370706 | 15010 | -0.260 | 0.0544 | No | ||
77 | RPL6 | 6040735 | 15035 | -0.263 | 0.0555 | No | ||
78 | PROS1 | 5420465 | 15076 | -0.274 | 0.0558 | No | ||
79 | GSPT2 | 6590674 | 15165 | -0.296 | 0.0537 | No | ||
80 | RPS16 | 510722 | 15218 | -0.314 | 0.0537 | No | ||
81 | RPS11 | 4120403 | 15288 | -0.336 | 0.0530 | No | ||
82 | RPS14 | 430541 | 15300 | -0.339 | 0.0554 | No | ||
83 | RPS5 | 580093 | 15345 | -0.353 | 0.0562 | No | ||
84 | FURIN | 4120168 | 15450 | -0.385 | 0.0540 | No | ||
85 | PIGA | 1940435 5290692 | 15487 | -0.403 | 0.0557 | No | ||
86 | RPS25 | 520139 | 15616 | -0.457 | 0.0529 | No | ||
87 | RPL8 | 20296 | 15702 | -0.498 | 0.0527 | No | ||
88 | RPLP1 | 3140292 | 15715 | -0.504 | 0.0566 | No | ||
89 | RPL28 | 6900136 | 15855 | -0.570 | 0.0542 | No | ||
90 | PIGH | 1500484 | 15935 | -0.619 | 0.0555 | No | ||
91 | EIF4H | 610324 | 15958 | -0.632 | 0.0599 | No | ||
92 | FAU | 7100465 | 16024 | -0.664 | 0.0624 | No | ||
93 | RPS29 | 580324 | 16239 | -0.797 | 0.0579 | No | ||
94 | EIF4E | 1580403 70133 6380215 | 16348 | -0.866 | 0.0599 | No | ||
95 | RPL19 | 5550592 | 16436 | -0.918 | 0.0634 | No | ||
96 | RPL11 | 3780435 | 16978 | -1.319 | 0.0460 | No | ||
97 | EIF4EBP1 | 60132 5720148 | 17318 | -1.734 | 0.0432 | No | ||
98 | TBCC | 4810021 | 17963 | -2.996 | 0.0353 | No |