DatasetSet_03_wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls
#wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls
#wtNotch_versus_normalThy_repos
Phenotypephenotype_wtNotch_versus_normalThy.cls#wtNotch_versus_normalThy_repos
Upregulated in classwtNotch
GeneSetREACTOME_METABOLISM_OF_PROTEINS
Enrichment Score (ES)0.66519064
Normalized Enrichment Score (NES)1.7798789
Nominal p-value0.0
FDR q-value0.0024217637
FWER p-Value0.022
Table: GSEA Results Summary



Fig 1: Enrichment plot: REACTOME_METABOLISM_OF_PROTEINS   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEDESCRIPTION
(from dataset)
GENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1EIF2B5430315 6900400108.7260.0776Yes
2EIF2S2770095 28104871164.6070.1132Yes
3RPS1958600661634.2570.1488Yes
4RPS3A24700861884.1010.1843Yes
5CCT6A23503682213.9440.2178Yes
6CCT371004033193.5350.2443Yes
7RPL3870040 4060138 62006014723.0010.2629Yes
8RPS2454203774872.9730.2888Yes
9ETF167700755822.7250.3081Yes
10RPL3048103696172.6720.3302Yes
11EIF2B14610082 70402426242.6620.3537Yes
12EIF4B5390563 52705776532.6100.3756Yes
13ACTB1660736 2030204 2060215 50500476652.5890.3982Yes
14EEF1D2320524 25103417012.5320.4190Yes
15CCT463801617882.3740.4356Yes
16PFDN641505198372.2840.4534Yes
17F257202808522.2550.4729Yes
18GPAA115004638732.2280.4917Yes
19TBCA64000959542.0950.5062Yes
20VBP140700509892.0570.5228Yes
21CCT2169011310961.9160.5342Yes
22CCT5105067011421.8620.5484Yes
23CCT8622001911981.8180.5617Yes
24DHPS534073512871.7300.5725Yes
25EIF4A11990341 281030014581.5760.5774Yes
26EIF2B2429004814641.5700.5912Yes
27F10383045016151.4180.5958Yes
28EIF4G1407044616191.4170.6083Yes
29RPS4X269002016891.3640.6168Yes
30RPS23710059417271.3250.6267Yes
31RPS15A117018017531.3020.6370Yes
32RPL14508047118091.2610.6453Yes
33PLAUR591028020961.0400.6392Yes
34PABPC12650180 2690253 6020632 199027021711.0000.6441Yes
35EEF1G394060323970.8820.6399Yes
36GAS6448002124090.8760.6471Yes
37RPS31570017 237017024770.8340.6510Yes
38DPM2361025325630.7810.6534Yes
39F7508041126160.7490.6573Yes
40RPL584009526610.7320.6615Yes
41RPS2134064727100.7060.6652Yes
42RPL37A704071731040.5370.6488No
43RPL42940014 542032432320.4870.6463No
44RPL18A457061932380.4850.6503No
45RPS13157036433340.4480.6492No
46GGCX770377 399044133390.4470.6530No
47RPS17236052837110.3200.6359No
48RPL27A3130451 110195 684049437670.3040.6356No
49DPM11240050 4810019 638039842930.2060.6091No
50EIF2S1536029244150.1890.6043No
51RPSA2360408 268073651910.1190.5635No
52PROC652027055960.0970.5425No
53PIGW481007263750.0650.5011No
54RPL41694011276390.0340.4332No
55PROZ344054176850.0330.4311No
56RPL172690167 569050478360.0310.4233No
57PFDN1700009579840.0280.4156No
58PIGP4280204 589044088640.0120.3682No
59PIGN421073690050.0100.3607No
60F9319015496440.0010.3263No
61TBCE52069210352-0.0090.2882No
62EIF5B1190102 420044011195-0.0230.2429No
63SEMA6D4050324 5860138 635030712780-0.0590.1579No
64RPS21312067313047-0.0680.1442No
65RPL27194008813280-0.0780.1323No
66EIF5638075013457-0.0860.1236No
67EEF21050369 4670035 589059813557-0.0900.1191No
68PIGF569005013830-0.1080.1054No
69RPL186380181 387019513885-0.1120.1034No
70RPL373170494 3870750 428049413891-0.1130.1042No
71RPS28383022113919-0.1140.1038No
72RPS1558010014572-0.1750.0701No
73RPLP2529002014619-0.1840.0693No
74RPS20174009214776-0.2090.0627No
75RPL39237044614790-0.2110.0639No
76RPL35A237070615010-0.2600.0544No
77RPL6604073515035-0.2630.0555No
78PROS1542046515076-0.2740.0558No
79GSPT2659067415165-0.2960.0537No
80RPS1651072215218-0.3140.0537No
81RPS11412040315288-0.3360.0530No
82RPS1443054115300-0.3390.0554No
83RPS558009315345-0.3530.0562No
84FURIN412016815450-0.3850.0540No
85PIGA1940435 529069215487-0.4030.0557No
86RPS2552013915616-0.4570.0529No
87RPL82029615702-0.4980.0527No
88RPLP1314029215715-0.5040.0566No
89RPL28690013615855-0.5700.0542No
90PIGH150048415935-0.6190.0555No
91EIF4H61032415958-0.6320.0599No
92FAU710046516024-0.6640.0624No
93RPS2958032416239-0.7970.0579No
94EIF4E1580403 70133 638021516348-0.8660.0599No
95RPL19555059216436-0.9180.0634No
96RPL11378043516978-1.3190.0460No
97EIF4EBP160132 572014817318-1.7340.0432No
98TBCC481002117963-2.9960.0353No
Table: GSEA details [plain text format]



Fig 2: REACTOME_METABOLISM_OF_PROTEINS   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: REACTOME_METABOLISM_OF_PROTEINS: Random ES distribution   
Gene set null distribution of ES for REACTOME_METABOLISM_OF_PROTEINS