DatasetSet_03_wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls
#wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls
#wtNotch_versus_normalThy_repos
Phenotypephenotype_wtNotch_versus_normalThy.cls#wtNotch_versus_normalThy_repos
Upregulated in classnormalThy
GeneSetREACTOME_COSTIMULATION_BY_THE_CD28_FAMILY
Enrichment Score (ES)-0.83906937
Normalized Enrichment Score (NES)-1.6716908
Nominal p-value0.0
FDR q-value0.04777466
FWER p-Value0.264
Table: GSEA Results Summary



Fig 1: Enrichment plot: REACTOME_COSTIMULATION_BY_THE_CD28_FAMILY   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEDESCRIPTION
(from dataset)		GENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1CD8087011228220.650-0.1361No
2PDCD1412008236670.333-0.1734No
3GRAP27100441 141064763760.065-0.3175No
4PIK3R1473067171650.043-0.3588No
5AKT1529074678080.031-0.3926No
6PTPN112230100 2470180 610052891680.008-0.4655No
7PIK3CA62201299883-0.003-0.5038No
8PAK1454031513219-0.075-0.6813No
9ICOSLG7012814566-0.175-0.7495No
10CD863390471 620028015804-0.543-0.8029No
11MAP3K8294028616231-0.789-0.8068Yes
12FYN2100468 4760520 485068716323-0.850-0.7911Yes
13CSK635059316555-0.997-0.7794Yes
14LCK336014217665-2.357-0.7821Yes
15CD281400739 421009317840-2.716-0.7258Yes
16VAV1602048717923-2.904-0.6600Yes
17CD3D281073917940-2.964-0.5893Yes
18CD4109001018200-3.836-0.5105Yes
19PDPK1665016818323-4.496-0.4084Yes
20CD3E380005618384-4.904-0.2931Yes
21CTLA4659053718511-6.266-0.1484Yes
22CD3G268028818515-6.3720.0054Yes
Table: GSEA details [plain text format]



Fig 2: REACTOME_COSTIMULATION_BY_THE_CD28_FAMILY   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: REACTOME_COSTIMULATION_BY_THE_CD28_FAMILY: Random ES distribution   
Gene set null distribution of ES for REACTOME_COSTIMULATION_BY_THE_CD28_FAMILY