Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_03_wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy_repos |
| Phenotype | phenotype_wtNotch_versus_normalThy.cls#wtNotch_versus_normalThy_repos |
| Upregulated in class | wtNotch |
| GeneSet | REACTOME_ASSEMBLY_OF_THE_PRE_REPLICATIVE_COMPLEX |
| Enrichment Score (ES) | 0.761649 |
| Normalized Enrichment Score (NES) | 1.7827622 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0028913505 |
| FWER p-Value | 0.021 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | PSMB1 | 2940402 | 120 | 4.592 | 0.0677 | Yes | ||
| 2 | PSMD14 | 5690593 | 297 | 3.628 | 0.1169 | Yes | ||
| 3 | PSMA4 | 4560427 | 344 | 3.426 | 0.1697 | Yes | ||
| 4 | PSMB10 | 630504 6510039 | 349 | 3.408 | 0.2246 | Yes | ||
| 5 | PSMC5 | 2760315 6550021 | 519 | 2.882 | 0.2621 | Yes | ||
| 6 | PSMC3 | 2480184 | 677 | 2.568 | 0.2951 | Yes | ||
| 7 | PSME3 | 2810537 | 703 | 2.529 | 0.3346 | Yes | ||
| 8 | PSMD12 | 730044 | 790 | 2.371 | 0.3683 | Yes | ||
| 9 | PSMD8 | 630142 | 846 | 2.266 | 0.4020 | Yes | ||
| 10 | PSMC2 | 7040010 | 854 | 2.254 | 0.4380 | Yes | ||
| 11 | PSMA7 | 2230131 | 925 | 2.151 | 0.4690 | Yes | ||
| 12 | PSMA2 | 6510093 | 973 | 2.074 | 0.5000 | Yes | ||
| 13 | PSMB9 | 6980471 | 1130 | 1.882 | 0.5220 | Yes | ||
| 14 | PSMB3 | 4280594 | 1211 | 1.799 | 0.5467 | Yes | ||
| 15 | PSMB5 | 6290242 | 1272 | 1.738 | 0.5716 | Yes | ||
| 16 | PSMB6 | 2690711 | 1374 | 1.653 | 0.5929 | Yes | ||
| 17 | PSMD3 | 1400647 | 1574 | 1.461 | 0.6057 | Yes | ||
| 18 | MCM6 | 60092 540181 6510110 | 1636 | 1.407 | 0.6252 | Yes | ||
| 19 | MCM5 | 2680647 | 1718 | 1.334 | 0.6424 | Yes | ||
| 20 | MCM3 | 5570068 | 1745 | 1.310 | 0.6621 | Yes | ||
| 21 | MCM4 | 2760673 5420711 | 1842 | 1.237 | 0.6770 | Yes | ||
| 22 | PSMC6 | 2810021 | 2104 | 1.035 | 0.6796 | Yes | ||
| 23 | PSMC4 | 580050 1580025 | 2169 | 1.001 | 0.6923 | Yes | ||
| 24 | PSMA5 | 5390537 | 2289 | 0.953 | 0.7013 | Yes | ||
| 25 | PSMD7 | 2030619 6220594 | 2407 | 0.876 | 0.7092 | Yes | ||
| 26 | E2F2 | 5270609 5570377 7000465 | 2470 | 0.839 | 0.7194 | Yes | ||
| 27 | MCM7 | 3290292 5220056 | 2495 | 0.823 | 0.7314 | Yes | ||
| 28 | GMNN | 2630148 | 2566 | 0.779 | 0.7402 | Yes | ||
| 29 | PSMC1 | 6350538 | 2674 | 0.725 | 0.7462 | Yes | ||
| 30 | PSME1 | 450193 4480035 | 2780 | 0.668 | 0.7513 | Yes | ||
| 31 | PSMD2 | 4670706 5050364 | 2788 | 0.664 | 0.7616 | Yes | ||
| 32 | MCM2 | 5050139 | 3072 | 0.548 | 0.7553 | No | ||
| 33 | PSMD10 | 520494 1170576 3830050 | 3463 | 0.403 | 0.7408 | No | ||
| 34 | ORC5L | 1940133 1940711 | 3531 | 0.381 | 0.7433 | No | ||
| 35 | ORC4L | 4230538 5550288 | 3728 | 0.315 | 0.7379 | No | ||
| 36 | ORC2L | 1990470 6510019 | 3929 | 0.269 | 0.7314 | No | ||
| 37 | PSMA6 | 50609 | 7110 | 0.045 | 0.5609 | No | ||
| 38 | PSMD5 | 3940139 4570041 | 9264 | 0.006 | 0.4451 | No | ||
| 39 | PSMA1 | 380059 2760195 | 9875 | -0.002 | 0.4123 | No | ||
| 40 | ORC1L | 2370328 6110390 | 11192 | -0.023 | 0.3418 | No | ||
| 41 | PSMB4 | 520402 | 14735 | -0.202 | 0.1543 | No | ||
| 42 | PSMD11 | 2340538 6510053 | 14886 | -0.231 | 0.1500 | No | ||
| 43 | PSMD4 | 430068 | 15355 | -0.356 | 0.1305 | No | ||
| 44 | PSMD9 | 50020 5890368 | 15775 | -0.532 | 0.1166 | No | ||
| 45 | PSMA3 | 5900047 7040161 | 16565 | -1.000 | 0.0902 | No | ||
| 46 | PSMB2 | 940035 4210324 | 16898 | -1.247 | 0.0925 | No |
