DatasetSet_03_wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls
#wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls
#wtNotch_versus_normalThy_repos
Phenotypephenotype_wtNotch_versus_normalThy.cls#wtNotch_versus_normalThy_repos
Upregulated in classwtNotch
GeneSetREACTOME_APC_C_CDH1_MEDIATED_DEGRADATION_OF_CDC20_AND_OTHER_APC_C_CDH1_TARGETED_PROTEINS_IN_LATE_MITOSIS_EARLY_G1
Enrichment Score (ES)0.77451676
Normalized Enrichment Score (NES)1.7846551
Nominal p-value0.0
FDR q-value0.0031592997
FWER p-Value0.02
Table: GSEA Results Summary



Fig 1: Enrichment plot: REACTOME_APC_C_CDH1_MEDIATED_DEGRADATION_OF_CDC20_AND_OTHER_APC_C_CDH1_TARGETED_PROTEINS_IN_LATE_MITOSIS_EARLY_G1   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEDESCRIPTION
(from dataset)		GENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1PSMB129404021204.5920.0756Yes
2PSMD1456905932973.6280.1309Yes
3PSMA445604273443.4260.1896Yes
4PSMB10630504 65100393493.4080.2503Yes
5PSMC52760315 65500215192.8820.2927Yes
6PSMC324801846772.5680.3301Yes
7PSME328105377032.5290.3739Yes
8PSMD127300447902.3710.4116Yes
9PSMD86301428462.2660.4492Yes
10PSMC270400108542.2540.4890Yes
11PSMA722301319252.1510.5237Yes
12PSMA265100939732.0740.5582Yes
13PSMB9698047111301.8820.5834Yes
14PSMB3428059412111.7990.6112Yes
15PSMB5629024212721.7380.6391Yes
16PSMB6269071113741.6530.6631Yes
17PTTG152046314671.5670.6862Yes
18UBE2E14230064 109044015121.5170.7109Yes
19PSMD3140064715741.4610.7337Yes
20PSMC6281002121041.0350.7237Yes
21PSMC4580050 158002521691.0010.7382Yes
22PSMA5539053722890.9530.7488Yes
23PSMD72030619 622059424070.8760.7581Yes
24PSMC1635053826740.7250.7568Yes
25PSME1450193 448003527800.6680.7630Yes
26PSMD24670706 505036427880.6640.7745Yes
27PSMD10520494 1170576 383005034630.4030.7454No
28CDC16194070649640.1340.6671No
29UBE2C613001751060.1250.6617No
30PSMA65060971100.0450.5547No
31PSMD53940139 457004192640.0060.4389No
32PSMA1380059 27601959875-0.0020.4062No
33UBE2D1185040010642-0.0140.3652No
34PSMB452040214735-0.2020.1485No
35PSMD112340538 651005314886-0.2310.1446No
36PSMD443006815355-0.3560.1257No
37PSMD950020 589036815775-0.5320.1127No
38PSMA35900047 704016116565-1.0000.0881No
39PSMB2940035 421032416898-1.2470.0925No
Table: GSEA details [plain text format]



Fig 2: REACTOME_APC_C_CDH1_MEDIATED_DEGRADATION_OF_CDC20_AND_OTHER_APC_C_CDH1_TARGETED_PROTEINS_IN_LATE_MITOSIS_EARLY_G1   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: REACTOME_APC_C_CDH1_MEDIATED_DEGRADATION_OF_CDC20_AND_OTHER_APC_C_CDH1_TARGETED_PROTEINS_IN_LATE_MITOSIS_EARLY_G1: Random ES distribution   
Gene set null distribution of ES for REACTOME_APC_C_CDH1_MEDIATED_DEGRADATION_OF_CDC20_AND_OTHER_APC_C_CDH1_TARGETED_PROTEINS_IN_LATE_MITOSIS_EARLY_G1