Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_03_absentNotch_versus_wtNotch.phenotype_absentNotch_versus_wtNotch.cls #wtNotch_versus_absentNotch |
| Phenotype | phenotype_absentNotch_versus_wtNotch.cls#wtNotch_versus_absentNotch |
| Upregulated in class | absentNotch |
| GeneSet | TRANSMEMBRANE_RECEPTOR_PROTEIN_SERINE_THREONINE_KINASE_SIGNALING_PATHWAY |
| Enrichment Score (ES) | -0.6671115 |
| Normalized Enrichment Score (NES) | -1.6611546 |
| Nominal p-value | 0.0018796993 |
| FDR q-value | 0.6763134 |
| FWER p-Value | 0.716 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | FNTA | 70059 | 1852 | 0.579 | -0.0541 | No | ||
| 2 | BMPR2 | 5340066 6960328 | 4278 | 0.138 | -0.1738 | No | ||
| 3 | TGFBR1 | 1400148 4280020 6550711 | 4580 | 0.118 | -0.1807 | No | ||
| 4 | FOXH1 | 2060180 | 5706 | 0.067 | -0.2360 | No | ||
| 5 | IL17F | 670577 | 5850 | 0.062 | -0.2388 | No | ||
| 6 | GDF10 | 4850082 | 6015 | 0.057 | -0.2431 | No | ||
| 7 | ENG | 4280270 | 6439 | 0.047 | -0.2622 | No | ||
| 8 | FMOD | 540577 | 6490 | 0.046 | -0.2613 | No | ||
| 9 | GDF5 | 510440 | 6775 | 0.039 | -0.2734 | No | ||
| 10 | SOST | 1170195 | 6899 | 0.037 | -0.2771 | No | ||
| 11 | KLF10 | 4850056 | 7040 | 0.034 | -0.2819 | No | ||
| 12 | SMAD7 | 430377 | 7519 | 0.026 | -0.3056 | No | ||
| 13 | ACVR2A | 6110647 | 8573 | 0.009 | -0.3616 | No | ||
| 14 | TGFBR3 | 5290577 | 8891 | 0.005 | -0.3783 | No | ||
| 15 | GDF9 | 2350181 | 9517 | -0.004 | -0.4116 | No | ||
| 16 | LEFTY2 | 5670364 | 10346 | -0.015 | -0.4550 | No | ||
| 17 | SNX6 | 6200086 | 10390 | -0.016 | -0.4561 | No | ||
| 18 | TGFB1 | 1940162 | 10755 | -0.021 | -0.4740 | No | ||
| 19 | CIDEA | 4560020 | 10797 | -0.022 | -0.4744 | No | ||
| 20 | ACVRL1 | 3290600 | 11411 | -0.032 | -0.5049 | No | ||
| 21 | SMAD1 | 630537 1850333 | 11611 | -0.036 | -0.5128 | No | ||
| 22 | RGMB | 670504 4570450 | 11682 | -0.037 | -0.5136 | No | ||
| 23 | HIPK2 | 6350647 | 12386 | -0.053 | -0.5473 | No | ||
| 24 | LTBP2 | 4850039 | 13395 | -0.084 | -0.5949 | No | ||
| 25 | GDF15 | 4730017 | 13560 | -0.091 | -0.5965 | No | ||
| 26 | SMAD2 | 4200592 | 13635 | -0.094 | -0.5931 | No | ||
| 27 | MAP3K7 | 6040068 | 13743 | -0.099 | -0.5911 | No | ||
| 28 | ACVR1B | 3610446 5570195 | 14236 | -0.128 | -0.6075 | No | ||
| 29 | ZFYVE9 | 6980288 7100017 | 15345 | -0.245 | -0.6478 | Yes | ||
| 30 | CDKN2B | 6020040 | 15576 | -0.285 | -0.6377 | Yes | ||
| 31 | ACVR1 | 6840671 | 15654 | -0.301 | -0.6181 | Yes | ||
| 32 | BMPR1A | 2190193 4060603 | 15801 | -0.335 | -0.5996 | Yes | ||
| 33 | HPGD | 6770192 | 15892 | -0.355 | -0.5764 | Yes | ||
| 34 | SMURF1 | 520609 580647 | 16168 | -0.424 | -0.5578 | Yes | ||
| 35 | CITED2 | 5670114 5130088 | 16426 | -0.502 | -0.5321 | Yes | ||
| 36 | EID2 | 3130176 | 17057 | -0.751 | -0.5068 | Yes | ||
| 37 | SMAD3 | 6450671 | 17125 | -0.778 | -0.4491 | Yes | ||
| 38 | SMAD5 | 5700497 | 17153 | -0.792 | -0.3881 | Yes | ||
| 39 | STUB1 | 5860086 | 17516 | -0.985 | -0.3299 | Yes | ||
| 40 | CDKN1C | 6520577 | 17550 | -0.999 | -0.2529 | Yes | ||
| 41 | SMAD4 | 5670519 | 17673 | -1.053 | -0.1765 | Yes | ||
| 42 | LEFTY1 | 3290452 | 17704 | -1.075 | -0.0933 | Yes | ||
| 43 | ACVR2B | 1660546 | 18371 | -1.806 | 0.0132 | Yes |
