Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_03_absentNotch_versus_wtNotch.phenotype_absentNotch_versus_wtNotch.cls #wtNotch_versus_absentNotch |
| Phenotype | phenotype_absentNotch_versus_wtNotch.cls#wtNotch_versus_absentNotch |
| Upregulated in class | absentNotch |
| GeneSet | MAGNESIUM_ION_BINDING |
| Enrichment Score (ES) | -0.61444515 |
| Normalized Enrichment Score (NES) | -1.5427637 |
| Nominal p-value | 0.009451796 |
| FDR q-value | 0.6942526 |
| FWER p-Value | 0.999 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | PINK1 | 380044 580577 | 853 | 1.024 | 0.0008 | No | ||
| 2 | HPRT1 | 1690398 4920619 6350170 | 1619 | 0.663 | -0.0101 | No | ||
| 3 | ABL1 | 1050593 2030050 4010114 | 1832 | 0.585 | 0.0052 | No | ||
| 4 | MAST1 | 6940215 | 2077 | 0.507 | 0.0152 | No | ||
| 5 | MARK2 | 7210608 | 2995 | 0.288 | -0.0210 | No | ||
| 6 | ERN1 | 2360403 | 3237 | 0.247 | -0.0227 | No | ||
| 7 | BRSK2 | 4050292 | 3849 | 0.175 | -0.0476 | No | ||
| 8 | MSH6 | 4480064 6520093 | 3939 | 0.166 | -0.0448 | No | ||
| 9 | TSSK6 | 2190136 | 4040 | 0.158 | -0.0429 | No | ||
| 10 | STK3 | 7100427 | 4217 | 0.142 | -0.0459 | No | ||
| 11 | SNRK | 630021 2030731 6350017 | 4525 | 0.121 | -0.0569 | No | ||
| 12 | STK38 | 7100114 | 4967 | 0.096 | -0.0763 | No | ||
| 13 | GCLC | 2810731 | 6878 | 0.038 | -0.1774 | No | ||
| 14 | TSSK2 | 5220324 | 7637 | 0.024 | -0.2172 | No | ||
| 15 | MAP2K7 | 2260086 | 8192 | 0.015 | -0.2463 | No | ||
| 16 | MOV10L1 | 4050411 | 8846 | 0.005 | -0.2812 | No | ||
| 17 | NLRC4 | 5570332 | 9146 | 0.002 | -0.2973 | No | ||
| 18 | MAP3K6 | 6400390 | 10277 | -0.014 | -0.3575 | No | ||
| 19 | SPHK1 | 2470113 4230398 6220397 | 10527 | -0.018 | -0.3700 | No | ||
| 20 | NLK | 2030010 2450041 | 10808 | -0.022 | -0.3841 | No | ||
| 21 | TGM3 | 840576 | 10854 | -0.023 | -0.3855 | No | ||
| 22 | SNF1LK2 | 4280739 2480463 | 11159 | -0.028 | -0.4006 | No | ||
| 23 | MAP3K5 | 6020041 6380162 | 11712 | -0.038 | -0.4286 | No | ||
| 24 | TSSK3 | 1740673 | 11850 | -0.041 | -0.4341 | No | ||
| 25 | ABL2 | 580021 | 12265 | -0.050 | -0.4541 | No | ||
| 26 | SNF1LK | 6110403 | 12549 | -0.056 | -0.4667 | No | ||
| 27 | STK38L | 840133 | 12886 | -0.066 | -0.4818 | No | ||
| 28 | CDC42BPA | 840671 | 12947 | -0.068 | -0.4819 | No | ||
| 29 | ERN2 | 7000411 | 13581 | -0.092 | -0.5118 | No | ||
| 30 | TSSK1A | 4480537 | 13687 | -0.097 | -0.5131 | No | ||
| 31 | SRPK2 | 6380341 | 13729 | -0.098 | -0.5108 | No | ||
| 32 | MARK1 | 450484 | 14998 | -0.198 | -0.5700 | No | ||
| 33 | MAPK12 | 450022 1340717 7050484 | 15286 | -0.236 | -0.5747 | No | ||
| 34 | NEK6 | 3360687 | 15498 | -0.272 | -0.5737 | No | ||
| 35 | FIGNL1 | 6860390 | 15783 | -0.331 | -0.5738 | No | ||
| 36 | CERK | 110397 670168 | 16272 | -0.454 | -0.5794 | No | ||
| 37 | NME1 | 770014 | 16924 | -0.688 | -0.5830 | Yes | ||
| 38 | ICK | 1580746 3140021 | 17065 | -0.752 | -0.5562 | Yes | ||
| 39 | MSH2 | 6180273 | 17144 | -0.787 | -0.5244 | Yes | ||
| 40 | CDC42BPB | 6350037 | 17177 | -0.805 | -0.4894 | Yes | ||
| 41 | IRAK3 | 4050102 | 17192 | -0.814 | -0.4530 | Yes | ||
| 42 | DYRK3 | 1090014 | 17436 | -0.947 | -0.4228 | Yes | ||
| 43 | STK11 | 6550278 | 17517 | -0.985 | -0.3821 | Yes | ||
| 44 | PRKACB | 4210170 | 17621 | -1.021 | -0.3410 | Yes | ||
| 45 | MTHFD2 | 3800411 | 17651 | -1.039 | -0.2951 | Yes | ||
| 46 | STK4 | 2640152 | 18025 | -1.319 | -0.2550 | Yes | ||
| 47 | MAST2 | 6200348 | 18344 | -1.734 | -0.1929 | Yes | ||
| 48 | SRPK1 | 450110 | 18484 | -2.155 | -0.1019 | Yes | ||
| 49 | TESC | 6550273 | 18542 | -2.385 | 0.0040 | Yes |
