Dataset | Set_03_absentNotch_versus_wtNotch.phenotype_absentNotch_versus_wtNotch.cls #wtNotch_versus_absentNotch |
Phenotype | phenotype_absentNotch_versus_wtNotch.cls#wtNotch_versus_absentNotch |
Upregulated in class | absentNotch |
GeneSet | REACTOME_HEMOSTASIS |
Enrichment Score (ES) | -0.5057481 |
Normalized Enrichment Score (NES) | -1.5094563 |
Nominal p-value | 0.0017301039 |
FDR q-value | 0.6370591 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | ALDOA | 6290672 | 72 | 2.228 | 0.0292 | No | ||
2 | ITGB2 | 6380348 | 303 | 1.590 | 0.0403 | No | ||
3 | SPN | 3520338 3870671 | 379 | 1.468 | 0.0581 | No | ||
4 | CD2 | 430672 | 433 | 1.387 | 0.0758 | No | ||
5 | CFL1 | 2340735 | 849 | 1.027 | 0.0686 | No | ||
6 | BSG | 2900193 6520053 | 881 | 1.007 | 0.0819 | No | ||
7 | PLCG2 | 5720008 | 1101 | 0.899 | 0.0834 | No | ||
8 | PTPN6 | 4230128 | 1132 | 0.885 | 0.0949 | No | ||
9 | ITGAL | 1450324 | 1192 | 0.848 | 0.1043 | No | ||
10 | SELP | 6040193 | 1269 | 0.808 | 0.1122 | No | ||
11 | PPIL2 | 6020279 | 1285 | 0.799 | 0.1232 | No | ||
12 | CSK | 6350593 | 1294 | 0.796 | 0.1346 | No | ||
13 | VAV1 | 6020487 | 1466 | 0.727 | 0.1361 | No | ||
14 | PIK3CG | 5890110 | 1823 | 0.589 | 0.1256 | No | ||
15 | SERPINB2 | 70487 | 2167 | 0.481 | 0.1142 | No | ||
16 | SOD1 | 5890070 | 2642 | 0.356 | 0.0938 | No | ||
17 | F7 | 5080411 | 2792 | 0.325 | 0.0906 | No | ||
18 | SELL | 1190500 | 2815 | 0.322 | 0.0941 | No | ||
19 | TBXA2R | 2370292 3940066 | 3016 | 0.286 | 0.0876 | No | ||
20 | KLKB1 | 5390446 | 3283 | 0.241 | 0.0768 | No | ||
21 | SOS1 | 7050338 | 3591 | 0.201 | 0.0631 | No | ||
22 | SLC16A3 | 1030564 4830452 | 3764 | 0.183 | 0.0565 | No | ||
23 | SERPINF2 | 2470390 2690292 | 3905 | 0.169 | 0.0514 | No | ||
24 | PPIA | 2900368 4850162 | 4070 | 0.156 | 0.0449 | No | ||
25 | F2R | 4810180 | 4071 | 0.155 | 0.0472 | No | ||
26 | ANGPT2 | 1230458 5720706 6040605 | 4110 | 0.151 | 0.0474 | No | ||
27 | F2 | 5720280 | 4430 | 0.127 | 0.0320 | No | ||
28 | APOB | 2370672 | 4502 | 0.123 | 0.0300 | No | ||
29 | GP5 | 2510088 | 4616 | 0.116 | 0.0256 | No | ||
30 | THBS1 | 4560494 430288 | 4657 | 0.114 | 0.0251 | No | ||
31 | FGG | 4610717 | 4777 | 0.107 | 0.0202 | No | ||
32 | GRB14 | 510035 3060369 | 4887 | 0.100 | 0.0158 | No | ||
33 | FN1 | 1170601 2970647 6220288 6940037 | 4923 | 0.099 | 0.0154 | No | ||
34 | EGF | 5220154 | 4980 | 0.096 | 0.0138 | No | ||
35 | VWF | 4670519 | 5064 | 0.092 | 0.0107 | No | ||
36 | ITGAM | 1190373 | 5752 | 0.065 | -0.0256 | No | ||
37 | PTPN1 | 2650056 | 5784 | 0.064 | -0.0263 | No | ||
38 | ITGA4 | 2470739 | 5878 | 0.061 | -0.0304 | No | ||
39 | LYN | 6040600 | 6066 | 0.056 | -0.0397 | No | ||
40 | ITGB3 | 5270463 | 6086 | 0.056 | -0.0399 | No | ||
41 | HGF | 3360593 | 6118 | 0.055 | -0.0408 | No | ||
42 | TEK | 6350541 | 6195 | 0.053 | -0.0441 | No | ||
43 | A2M | 6620039 | 6360 | 0.049 | -0.0522 | No | ||
44 | OLR1 | 50025 3840484 | 6735 | 0.040 | -0.0719 | No | ||
45 | SPARC | 1690086 | 7266 | 0.030 | -0.1001 | No | ||
46 | FGB | 7000010 | 7488 | 0.026 | -0.1117 | No | ||
47 | SERPINE1 | 4210403 | 7590 | 0.025 | -0.1168 | No | ||
48 | LCP2 | 2680066 6650707 | 7738 | 0.022 | -0.1245 | No | ||
49 | PLA2G4A | 6380364 | 7770 | 0.021 | -0.1258 | No | ||
50 | GP1BA | 6590372 | 7957 | 0.019 | -0.1356 | No | ||
51 | CD48 | 1570647 | 8199 | 0.015 | -0.1484 | No | ||
52 | HRG | 2340161 | 8227 | 0.015 | -0.1497 | No | ||
53 | CD36 | 5890575 | 8238 | 0.014 | -0.1500 | No | ||
54 | PIK3R1 | 4730671 | 8630 | 0.008 | -0.1711 | No | ||
55 | SERPINC1 | 1780717 | 8659 | 0.008 | -0.1724 | No | ||
56 | PROC | 6520270 | 8842 | 0.005 | -0.1822 | No | ||
57 | ANGPT1 | 3990368 5130288 6770035 | 8885 | 0.005 | -0.1844 | No | ||
58 | ITGA2B | 2680538 | 8927 | 0.004 | -0.1866 | No | ||
59 | ADRA2A | 5340520 | 9041 | 0.003 | -0.1927 | No | ||
60 | AKT1 | 5290746 | 9115 | 0.002 | -0.1966 | No | ||
61 | APBB1IP | 4560441 4570706 6520739 | 9325 | -0.001 | -0.2079 | No | ||
62 | F3 | 2940180 | 9901 | -0.009 | -0.2389 | No | ||
63 | F9 | 3190154 | 9983 | -0.010 | -0.2431 | No | ||
64 | FCER1G | 5550020 | 10022 | -0.011 | -0.2450 | No | ||
65 | F13B | 6220278 | 10042 | -0.011 | -0.2459 | No | ||
66 | KNG1 | 6400576 6770347 | 10116 | -0.012 | -0.2497 | No | ||
67 | CAV1 | 870025 | 10151 | -0.013 | -0.2513 | No | ||
68 | F2RL2 | 6110736 | 10266 | -0.014 | -0.2573 | No | ||
69 | F8 | 2190647 2340465 | 10330 | -0.015 | -0.2605 | No | ||
70 | LEFTY2 | 5670364 | 10346 | -0.015 | -0.2610 | No | ||
71 | GP9 | 1190181 | 10431 | -0.017 | -0.2653 | No | ||
72 | PLG | 3360270 3840100 | 10651 | -0.020 | -0.2769 | No | ||
73 | P2RY1 | 6040121 | 10954 | -0.025 | -0.2929 | No | ||
74 | CFD | 2320736 | 11161 | -0.028 | -0.3036 | No | ||
75 | PPBP | 5130446 | 11414 | -0.032 | -0.3168 | No | ||
76 | PTPN11 | 2230100 2470180 6100528 | 11527 | -0.034 | -0.3223 | No | ||
77 | SHC1 | 2900731 3170504 6520537 | 11609 | -0.036 | -0.3262 | No | ||
78 | CXADR | 6370068 | 11773 | -0.039 | -0.3344 | No | ||
79 | BCAR1 | 1340215 | 11859 | -0.041 | -0.3384 | No | ||
80 | GP1BB | 3780075 | 11895 | -0.041 | -0.3397 | No | ||
81 | TMSB4X | 6620114 | 12177 | -0.048 | -0.3542 | No | ||
82 | SYK | 6940133 | 12413 | -0.053 | -0.3661 | No | ||
83 | RAP1A | 1090025 | 12489 | -0.055 | -0.3694 | No | ||
84 | MAG | 2370037 | 12583 | -0.057 | -0.3736 | No | ||
85 | ITGA5 | 5550520 | 12796 | -0.064 | -0.3841 | No | ||
86 | ITGAX | 6130524 | 12847 | -0.065 | -0.3858 | No | ||
87 | HSPA5 | 5130671 | 12931 | -0.068 | -0.3893 | No | ||
88 | PLEK | 1090039 | 13099 | -0.073 | -0.3973 | No | ||
89 | F5 | 1990619 | 13117 | -0.074 | -0.3971 | No | ||
90 | STXBP3 | 780706 | 13148 | -0.075 | -0.3976 | No | ||
91 | CALM1 | 380128 | 13169 | -0.076 | -0.3976 | No | ||
92 | JAM2 | 1410164 5080114 5290541 | 13193 | -0.076 | -0.3977 | No | ||
93 | THBD | 1500092 | 13435 | -0.086 | -0.4094 | No | ||
94 | MMRN1 | 7050278 | 13437 | -0.086 | -0.4082 | No | ||
95 | PROS1 | 5420465 | 13452 | -0.086 | -0.4077 | No | ||
96 | PLAT | 6860128 | 13534 | -0.090 | -0.4108 | No | ||
97 | F10 | 3830450 | 13593 | -0.092 | -0.4125 | No | ||
98 | F11 | 6370577 6510373 | 13932 | -0.109 | -0.4292 | No | ||
99 | GNAQ | 430670 4210131 5900736 | 13945 | -0.110 | -0.4282 | No | ||
100 | COL1A1 | 730020 | 14172 | -0.124 | -0.4386 | No | ||
101 | F12 | 1090215 3520736 | 14530 | -0.150 | -0.4557 | No | ||
102 | PLCG1 | 6020369 | 14633 | -0.160 | -0.4589 | No | ||
103 | FGA | 4210056 5220239 | 14963 | -0.193 | -0.4738 | No | ||
104 | APOA1 | 110152 | 15531 | -0.278 | -0.5004 | No | ||
105 | P2RX1 | 2940021 3290338 | 15631 | -0.296 | -0.5014 | Yes | ||
106 | FYN | 2100468 4760520 4850687 | 15696 | -0.311 | -0.5002 | Yes | ||
107 | ITGAV | 2340020 | 15734 | -0.319 | -0.4975 | Yes | ||
108 | PSAP | 2810338 | 15739 | -0.320 | -0.4929 | Yes | ||
109 | TIMP1 | 1010326 | 15882 | -0.351 | -0.4954 | Yes | ||
110 | COL1A2 | 380364 | 15969 | -0.373 | -0.4945 | Yes | ||
111 | DOK2 | 5340273 | 16025 | -0.389 | -0.4917 | Yes | ||
112 | CALU | 2680403 3520056 4610348 5720176 6130121 | 16074 | -0.400 | -0.4884 | Yes | ||
113 | CD47 | 1850603 | 16127 | -0.413 | -0.4851 | Yes | ||
114 | CAP1 | 2650278 | 16144 | -0.417 | -0.4797 | Yes | ||
115 | MAPK14 | 5290731 | 16148 | -0.418 | -0.4737 | Yes | ||
116 | SERPING1 | 5550440 | 16170 | -0.424 | -0.4685 | Yes | ||
117 | PLAUR | 5910280 | 16201 | -0.432 | -0.4637 | Yes | ||
118 | TUBA4A | 6900279 | 16358 | -0.484 | -0.4650 | Yes | ||
119 | MERTK | 6420056 | 16571 | -0.553 | -0.4683 | Yes | ||
120 | C1QBP | 3170452 | 16584 | -0.556 | -0.4607 | Yes | ||
121 | STX4 | 6270632 | 16609 | -0.564 | -0.4536 | Yes | ||
122 | TFPI | 1400288 5550008 | 16840 | -0.652 | -0.4563 | Yes | ||
123 | IGF1 | 1990193 3130377 3290280 | 16886 | -0.674 | -0.4488 | Yes | ||
124 | WDR1 | 1090129 3990121 | 16935 | -0.692 | -0.4411 | Yes | ||
125 | KRAS | 2060170 | 16950 | -0.698 | -0.4315 | Yes | ||
126 | LAMP2 | 1230402 1980373 | 17408 | -0.932 | -0.4424 | Yes | ||
127 | GAS6 | 4480021 | 17500 | -0.979 | -0.4328 | Yes | ||
128 | PIK3CB | 3800600 | 17779 | -1.134 | -0.4310 | Yes | ||
129 | CLU | 5420075 | 17796 | -1.148 | -0.4148 | Yes | ||
130 | PDPK1 | 6650168 | 17818 | -1.163 | -0.3987 | Yes | ||
131 | PLAU | 6510047 | 17819 | -1.164 | -0.3814 | Yes | ||
132 | PFN1 | 6130132 | 17829 | -1.169 | -0.3645 | Yes | ||
133 | FYB | 1690440 | 17835 | -1.178 | -0.3473 | Yes | ||
134 | APP | 2510053 | 17838 | -1.180 | -0.3299 | Yes | ||
135 | GNA13 | 4590102 | 17876 | -1.205 | -0.3140 | Yes | ||
136 | ACTN4 | 3840301 4590390 7050132 | 18044 | -1.337 | -0.3032 | Yes | ||
137 | FLNA | 5390193 | 18128 | -1.422 | -0.2865 | Yes | ||
138 | GNB1 | 2120397 | 18190 | -1.508 | -0.2675 | Yes | ||
139 | PF4 | 6130332 | 18220 | -1.542 | -0.2461 | Yes | ||
140 | GNG2 | 2230390 | 18284 | -1.627 | -0.2254 | Yes | ||
141 | VCL | 4120487 | 18343 | -1.734 | -0.2028 | Yes | ||
142 | GRB7 | 2100471 | 18367 | -1.791 | -0.1774 | Yes | ||
143 | CD9 | 4730041 | 18408 | -1.912 | -0.1512 | Yes | ||
144 | CD63 | 6660451 | 18443 | -1.986 | -0.1235 | Yes | ||
145 | ITGB1 | 5080156 6270528 | 18580 | -2.818 | -0.0891 | Yes | ||
146 | PTK2 | 1780148 | 18588 | -3.004 | -0.0448 | Yes | ||
147 | PRKCZ | 3780279 | 18595 | -3.117 | 0.0011 | Yes |