Dataset | Set_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls #truncNotch_versus_wtNotch |
Phenotype | phenotype_truncNotch_versus_wtNotch.cls#truncNotch_versus_wtNotch |
Upregulated in class | wtNotch |
GeneSet | MITOTIC_CELL_CYCLE |
Enrichment Score (ES) | -0.5169219 |
Normalized Enrichment Score (NES) | -1.5801877 |
Nominal p-value | 0.0 |
FDR q-value | 0.31520826 |
FWER p-Value | 0.995 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | CDK10 | 60164 1190717 3130128 3990044 | 93 | 3.142 | 0.0286 | No | ||
2 | BCAT1 | 3290128 4050408 | 146 | 2.890 | 0.0567 | No | ||
3 | SMAD3 | 6450671 | 421 | 2.238 | 0.0658 | No | ||
4 | CDK4 | 540075 4540600 | 515 | 2.120 | 0.0834 | No | ||
5 | MAD2L2 | 1240358 | 828 | 1.784 | 0.0856 | No | ||
6 | CHMP1A | 5550441 | 965 | 1.647 | 0.0959 | No | ||
7 | CDC25B | 6940102 | 1097 | 1.538 | 0.1053 | No | ||
8 | CHFR | 3390050 6450300 6450736 | 1489 | 1.272 | 0.0977 | No | ||
9 | MAP3K11 | 7000039 | 1593 | 1.210 | 0.1051 | No | ||
10 | POLD1 | 4830026 | 1795 | 1.079 | 0.1058 | No | ||
11 | TARDBP | 870390 2350093 | 2164 | 0.917 | 0.0957 | No | ||
12 | CDKN2C | 5050750 5130148 | 2627 | 0.707 | 0.0782 | No | ||
13 | TGFB1 | 1940162 | 2867 | 0.610 | 0.0718 | No | ||
14 | NUMA1 | 6520576 | 3038 | 0.548 | 0.0685 | No | ||
15 | E2F1 | 5360093 | 3237 | 0.483 | 0.0629 | No | ||
16 | CDK6 | 4920253 | 3281 | 0.469 | 0.0656 | No | ||
17 | APBB1 | 2690338 | 3475 | 0.422 | 0.0597 | No | ||
18 | CDKN2D | 6040035 | 3716 | 0.370 | 0.0507 | No | ||
19 | DCTN2 | 540471 3780717 | 3928 | 0.333 | 0.0428 | No | ||
20 | CUL2 | 4200278 | 4121 | 0.298 | 0.0356 | No | ||
21 | TPD52L1 | 4590711 5570575 | 4391 | 0.260 | 0.0239 | No | ||
22 | ASNS | 110368 7100687 | 4447 | 0.253 | 0.0236 | No | ||
23 | RCC1 | 2480358 | 4488 | 0.246 | 0.0241 | No | ||
24 | ACVR1 | 6840671 | 4652 | 0.228 | 0.0177 | No | ||
25 | DLG1 | 2630091 6020286 | 5006 | 0.191 | 0.0006 | No | ||
26 | ANAPC11 | 1780601 | 5028 | 0.189 | 0.0015 | No | ||
27 | CDKN2B | 6020040 | 5044 | 0.187 | 0.0027 | No | ||
28 | ANLN | 1780113 2470537 6840047 | 5049 | 0.187 | 0.0045 | No | ||
29 | UBE2C | 6130017 | 5204 | 0.173 | -0.0020 | No | ||
30 | PLK1 | 1780369 2640121 | 5389 | 0.159 | -0.0102 | No | ||
31 | CDCA5 | 5670131 | 5416 | 0.156 | -0.0100 | No | ||
32 | TBRG4 | 3610239 6370594 | 5750 | 0.133 | -0.0266 | No | ||
33 | CENPE | 2850022 | 5869 | 0.126 | -0.0316 | No | ||
34 | SPHK1 | 2470113 4230398 6220397 | 6078 | 0.115 | -0.0416 | No | ||
35 | NEK6 | 3360687 | 6197 | 0.109 | -0.0468 | No | ||
36 | CUL5 | 450142 | 6527 | 0.094 | -0.0636 | No | ||
37 | CLIP1 | 2850162 6770397 | 6789 | 0.084 | -0.0768 | No | ||
38 | PAFAH1B1 | 4230333 6420121 6450066 | 7219 | 0.070 | -0.0993 | No | ||
39 | NEK2 | 2120520 | 7723 | 0.056 | -0.1259 | No | ||
40 | KATNA1 | 6290048 | 7912 | 0.051 | -0.1355 | No | ||
41 | APBB2 | 5130403 | 7933 | 0.051 | -0.1361 | No | ||
42 | CETN1 | 6020056 | 7956 | 0.050 | -0.1367 | No | ||
43 | SNF1LK | 6110403 | 8053 | 0.048 | -0.1414 | No | ||
44 | PRMT5 | 2760180 4590072 | 8107 | 0.047 | -0.1438 | No | ||
45 | TTN | 2320161 4670056 6550026 | 8471 | 0.039 | -0.1630 | No | ||
46 | CDKN3 | 110520 | 8482 | 0.039 | -0.1631 | No | ||
47 | KIF11 | 5390139 | 9245 | 0.025 | -0.2040 | No | ||
48 | FOXC1 | 580239 | 9314 | 0.024 | -0.2075 | No | ||
49 | POLA1 | 4760541 | 9609 | 0.018 | -0.2232 | No | ||
50 | BUB1 | 5390270 | 10159 | 0.009 | -0.2528 | No | ||
51 | EREG | 50519 4920129 | 10683 | 0.001 | -0.2811 | No | ||
52 | BTG3 | 7050079 | 10953 | -0.004 | -0.2956 | No | ||
53 | KIF2C | 6940082 | 11750 | -0.018 | -0.3384 | No | ||
54 | CDKN1A | 4050088 6400706 | 11801 | -0.019 | -0.3409 | No | ||
55 | RAN | 2260446 4590647 | 11827 | -0.019 | -0.3421 | No | ||
56 | ANAPC10 | 870086 1170037 2260129 | 11843 | -0.019 | -0.3427 | No | ||
57 | PAM | 5290528 | 11865 | -0.020 | -0.3436 | No | ||
58 | CENPF | 5050088 | 11951 | -0.022 | -0.3480 | No | ||
59 | TTK | 3800129 | 12149 | -0.026 | -0.3583 | No | ||
60 | EPGN | 6980450 | 13283 | -0.059 | -0.4190 | No | ||
61 | NBN | 730538 2470619 4780594 | 13322 | -0.060 | -0.4204 | No | ||
62 | KIF15 | 610731 4070731 6520014 | 13416 | -0.064 | -0.4248 | No | ||
63 | CDC23 | 3190593 | 13459 | -0.066 | -0.4263 | No | ||
64 | DCTN3 | 6840131 | 13849 | -0.085 | -0.4465 | No | ||
65 | ATM | 3610110 4050524 | 13930 | -0.090 | -0.4498 | No | ||
66 | FBXO5 | 2630551 | 13963 | -0.092 | -0.4506 | No | ||
67 | PML | 50093 2190435 2450402 3840082 | 13983 | -0.093 | -0.4506 | No | ||
68 | USH1C | 1570372 4230364 | 14222 | -0.110 | -0.4623 | No | ||
69 | CDC25C | 2570673 4760161 6520707 | 14375 | -0.124 | -0.4692 | No | ||
70 | DDX11 | 6590671 | 14481 | -0.133 | -0.4734 | No | ||
71 | CDKN1B | 3800025 6450044 | 14572 | -0.142 | -0.4768 | No | ||
72 | NPM2 | 6040139 | 14613 | -0.148 | -0.4774 | No | ||
73 | SMC3 | 870546 1400411 5700039 6450577 | 14706 | -0.158 | -0.4807 | No | ||
74 | TGFA | 1570332 | 14796 | -0.172 | -0.4836 | No | ||
75 | PIN1 | 2970408 | 14858 | -0.180 | -0.4850 | No | ||
76 | GFI1B | 4570131 | 15009 | -0.204 | -0.4909 | No | ||
77 | ACVR1B | 3610446 5570195 | 15345 | -0.272 | -0.5062 | No | ||
78 | CDK2 | 130484 2260301 4010088 5050110 | 15400 | -0.284 | -0.5060 | No | ||
79 | RAD17 | 5220739 | 15422 | -0.288 | -0.5041 | No | ||
80 | LATS2 | 4480593 6020494 | 15450 | -0.294 | -0.5024 | No | ||
81 | KIF22 | 1190368 | 15549 | -0.321 | -0.5043 | No | ||
82 | GFI1 | 730180 | 15709 | -0.371 | -0.5089 | No | ||
83 | NOLC1 | 2350195 | 15741 | -0.381 | -0.5065 | No | ||
84 | PPP5C | 3130047 | 15821 | -0.409 | -0.5064 | No | ||
85 | SSSCA1 | 1240402 780309 | 16008 | -0.469 | -0.5115 | No | ||
86 | CUL4A | 1170088 2320008 2470278 | 16110 | -0.504 | -0.5115 | Yes | ||
87 | EGF | 5220154 | 16142 | -0.515 | -0.5077 | Yes | ||
88 | SMC4 | 5910240 | 16168 | -0.524 | -0.5035 | Yes | ||
89 | CIT | 2370601 | 16181 | -0.528 | -0.4985 | Yes | ||
90 | SUGT1 | 1690670 | 16186 | -0.532 | -0.4930 | Yes | ||
91 | CCNA2 | 5290075 | 16440 | -0.634 | -0.4999 | Yes | ||
92 | STMN1 | 1990717 | 16449 | -0.636 | -0.4935 | Yes | ||
93 | CDC6 | 4570296 5360600 | 16457 | -0.641 | -0.4870 | Yes | ||
94 | DLG7 | 3120041 | 16674 | -0.763 | -0.4906 | Yes | ||
95 | CDK2AP1 | 2340156 | 16688 | -0.770 | -0.4830 | Yes | ||
96 | ABL1 | 1050593 2030050 4010114 | 16718 | -0.789 | -0.4762 | Yes | ||
97 | BIRC5 | 110408 580014 1770632 | 16722 | -0.790 | -0.4679 | Yes | ||
98 | KNTC1 | 430079 | 16964 | -0.940 | -0.4709 | Yes | ||
99 | CDC16 | 1940706 | 17027 | -0.980 | -0.4637 | Yes | ||
100 | CD28 | 1400739 4210093 | 17038 | -0.983 | -0.4538 | Yes | ||
101 | PCBP4 | 6350722 | 17053 | -0.991 | -0.4439 | Yes | ||
102 | CDKN2A | 4670215 4760047 | 17236 | -1.090 | -0.4421 | Yes | ||
103 | ZW10 | 2900735 3520687 | 17254 | -1.103 | -0.4312 | Yes | ||
104 | SMC1A | 3060600 5700148 5890113 6370154 | 17283 | -1.130 | -0.4207 | Yes | ||
105 | AURKA | 780537 | 17299 | -1.140 | -0.4093 | Yes | ||
106 | KHDRBS1 | 1240403 6040040 | 17319 | -1.152 | -0.3980 | Yes | ||
107 | MPHOSPH6 | 5570164 | 17437 | -1.259 | -0.3908 | Yes | ||
108 | CDKN1C | 6520577 | 17535 | -1.353 | -0.3816 | Yes | ||
109 | GSPT1 | 5420050 | 17593 | -1.408 | -0.3697 | Yes | ||
110 | KIF23 | 5570112 | 17597 | -1.409 | -0.3547 | Yes | ||
111 | PRC1 | 870092 5890204 | 17654 | -1.472 | -0.3420 | Yes | ||
112 | ZWINT | 6940670 | 17662 | -1.481 | -0.3266 | Yes | ||
113 | NDC80 | 4120465 | 17749 | -1.583 | -0.3143 | Yes | ||
114 | PPP6C | 2450670 | 17776 | -1.613 | -0.2985 | Yes | ||
115 | CUL1 | 1990632 | 17844 | -1.677 | -0.2841 | Yes | ||
116 | CDC7 | 4060546 4850041 | 17891 | -1.718 | -0.2683 | Yes | ||
117 | NUSAP1 | 940048 3120435 | 17902 | -1.733 | -0.2503 | Yes | ||
118 | ANAPC5 | 730164 7100685 | 18019 | -1.862 | -0.2366 | Yes | ||
119 | SKP2 | 360711 380093 4810368 | 18133 | -2.012 | -0.2212 | Yes | ||
120 | CUL3 | 1850520 | 18170 | -2.066 | -0.2011 | Yes | ||
121 | TPX2 | 6420324 | 18310 | -2.306 | -0.1839 | Yes | ||
122 | MAD2L1 | 4480725 | 18343 | -2.379 | -0.1602 | Yes | ||
123 | ANAPC4 | 4540338 | 18344 | -2.384 | -0.1347 | Yes | ||
124 | POLE | 6020538 | 18351 | -2.398 | -0.1094 | Yes | ||
125 | BUB1B | 1450288 | 18355 | -2.413 | -0.0837 | Yes | ||
126 | KPNA2 | 3450114 | 18491 | -2.781 | -0.0613 | Yes | ||
127 | AKAP8 | 4210026 | 18559 | -3.171 | -0.0310 | Yes | ||
128 | NCAPH | 6220435 | 18560 | -3.183 | 0.0030 | Yes |