Details for gene set CELL_CYCLE_GO

Table: GSEA Results Summary

Dataset	Set_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls #truncNotch_versus_wtNotch
Phenotype	phenotype_truncNotch_versus_wtNotch.cls#truncNotch_versus_wtNotch
Upregulated in class	wtNotch
GeneSet	CELL_CYCLE_GO_0007049
Enrichment Score (ES)	-0.49356228
Normalized Enrichment Score (NES)	-1.6298705
Nominal p-value	0.0
FDR q-value	0.28114828
FWER p-Value	0.94

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	CDK10	60164 1190717 3130128 3990044	93	3.142	0.0131	No
2	BCAT1	3290128 4050408	146	2.890	0.0269	No
3	DTYMK	2340377	235	2.603	0.0372	No
4	SMAD3	6450671	421	2.238	0.0400	No
5	CDK4	540075 4540600	515	2.120	0.0472	No
6	BMP7	870039	571	2.053	0.0561	No
7	ERCC2	2360750 4060390 6550138	712	1.897	0.0594	No
8	ZBTB17	6220082	731	1.873	0.0692	No
9	MAD2L2	1240358	828	1.784	0.0743	No
10	MSH5	1340019 4730333	961	1.651	0.0767	No
11	CHMP1A	5550441	965	1.647	0.0860	No
12	CDC25B	6940102	1097	1.538	0.0878	No
13	BCCIP	670450 2650750 5270519 6660711	1156	1.494	0.0932	No
14	CHFR	3390050 6450300 6450736	1489	1.272	0.0825	No
15	MAP3K11	7000039	1593	1.210	0.0839	No
16	POLD1	4830026	1795	1.079	0.0791	No
17	MFN2	2260195 6100164	1974	1.000	0.0752	No
18	STK11	6550278	2047	0.974	0.0769	No
19	DDB1	6110687	2145	0.927	0.0770	No
20	TARDBP	870390 2350093	2164	0.917	0.0813	No
21	CDKN2C	5050750 5130148	2627	0.707	0.0602	No
22	STAG3	3830112	2683	0.682	0.0612	No
23	RHOB	1500309	2694	0.678	0.0645	No
24	CDK5RAP3	3130576	2764	0.643	0.0645	No
25	PA2G4	2030463	2777	0.638	0.0675	No
26	TGFB1	1940162	2867	0.610	0.0662	No
27	HPGD	6770192	2902	0.599	0.0678	No
28	NUMA1	6520576	3038	0.548	0.0636	No
29	BOLL	6100743	3048	0.545	0.0663	No
30	GADD45A	2900717	3144	0.512	0.0641	No
31	CDK5RAP1	2570471 4010465 5960161	3210	0.491	0.0633	No
32	E2F1	5360093	3237	0.483	0.0647	No
33	TOP3A	7000435	3266	0.476	0.0659	No
34	CDK6	4920253	3281	0.469	0.0679	No
35	CHEK2	610139 1050022	3297	0.465	0.0698	No
36	MCM2	5050139	3319	0.459	0.0713	No
37	TP53	6130707	3380	0.442	0.0705	No
38	RACGAP1	3990162 6620736	3408	0.437	0.0716	No
39	APBB1	2690338	3475	0.422	0.0704	No
40	CENTD2	60408 2510156 6100494	3504	0.415	0.0713	No
41	CDC20	3440017 3440044 6220088	3513	0.413	0.0733	No
42	SERTAD1	2680332	3548	0.408	0.0738	No
43	CDKN2D	6040035	3716	0.370	0.0668	No
44	PFDN1	7000095	3815	0.350	0.0635	No
45	TBX3	2570672	3834	0.348	0.0645	No
46	DCTN2	540471 3780717	3928	0.333	0.0614	No
47	UHMK1	3850670 6450064	3977	0.324	0.0606	No
48	MAPK12	450022 1340717 7050484	4012	0.318	0.0606	No
49	CUL2	4200278	4121	0.298	0.0565	No
50	NEK11	5360369 7380521	4243	0.278	0.0515	No
51	RAD54L	2970041	4258	0.276	0.0523	No
52	TPD52L1	4590711 5570575	4391	0.260	0.0466	No
53	ASNS	110368 7100687	4447	0.253	0.0451	No
54	RCC1	2480358	4488	0.246	0.0443	No
55	PLAGL1	3190082 6200193	4502	0.243	0.0450	No
56	PPM1G	610725	4570	0.236	0.0427	No
57	ACVR1	6840671	4652	0.228	0.0396	No
58	CITED2	5670114 5130088	4784	0.213	0.0337	No
59	DUSP13	6400152	4807	0.211	0.0337	No
60	DLG1	2630091 6020286	5006	0.191	0.0240	No
61	ANAPC11	1780601	5028	0.189	0.0240	No
62	CDKN2B	6020040	5044	0.187	0.0243	No
63	ANLN	1780113 2470537 6840047	5049	0.187	0.0251	No
64	AHR	4560671	5070	0.185	0.0251	No
65	UBE2C	6130017	5204	0.173	0.0188	No
66	FANCG	4010471	5351	0.161	0.0118	No
67	PLK1	1780369 2640121	5389	0.159	0.0107	No
68	CDCA5	5670131	5416	0.156	0.0102	No
69	CCNT1	2450563 5390184	5523	0.149	0.0053	No
70	TBRG4	3610239 6370594	5750	0.133	-0.0063	No
71	CENPE	2850022	5869	0.126	-0.0120	No
72	RAD1	4200551	5893	0.125	-0.0125	No
73	RUNX3	3800546	5980	0.121	-0.0165	No
74	PPP1R13B	4010605 4760181	6064	0.116	-0.0203	No
75	ANAPC2	6660438	6066	0.116	-0.0197	No
76	SPHK1	2470113 4230398 6220397	6078	0.115	-0.0197	No
77	NEK6	3360687	6197	0.109	-0.0255	No
78	CUL5	450142	6527	0.094	-0.0428	No
79	DMC1	450341	6562	0.092	-0.0442	No
80	TGFB2	4920292	6752	0.085	-0.0540	No
81	CLIP1	2850162 6770397	6789	0.084	-0.0554	No
82	BTG4	4060020	6852	0.082	-0.0583	No
83	XPC	6370193	6913	0.079	-0.0612	No
84	GPS1	2470037 4760315 6200528 7100040	6981	0.077	-0.0644	No
85	CDK5R2	3800110	7159	0.072	-0.0736	No
86	PAFAH1B1	4230333 6420121 6450066	7219	0.070	-0.0764	No
87	HERC5	4280687	7393	0.065	-0.0855	No
88	NEK2	2120520	7723	0.056	-0.1031	No
89	CDK7	2640451	7739	0.056	-0.1036	No
90	RPRM	1580706	7855	0.053	-0.1095	No
91	KATNA1	6290048	7912	0.051	-0.1123	No
92	APBB2	5130403	7933	0.051	-0.1131	No
93	PPP1R9B	3130619	7938	0.051	-0.1130	No
94	CETN1	6020056	7956	0.050	-0.1136	No
95	SNF1LK	6110403	8053	0.048	-0.1186	No
96	PRMT5	2760180 4590072	8107	0.047	-0.1212	No
97	BMP2	6620687	8294	0.042	-0.1311	No
98	INHA	6100102	8332	0.042	-0.1329	No
99	ALOX15B	450736	8398	0.040	-0.1362	No
100	TTN	2320161 4670056 6550026	8471	0.039	-0.1399	No
101	CDKN3	110520	8482	0.039	-0.1402	No
102	TIMELESS	3710315	8536	0.038	-0.1429	No
103	CKS2	1410156	9063	0.028	-0.1714	No
104	KIF11	5390139	9245	0.025	-0.1811	No
105	FOXC1	580239	9314	0.024	-0.1847	No
106	EGFL6	3940181	9349	0.023	-0.1864	No
107	NPM1	4730427	9492	0.020	-0.1940	No
108	POLA1	4760541	9609	0.018	-0.2002	No
109	MSH4	3940068	9622	0.018	-0.2008	No
110	CCND2	5340167	9898	0.014	-0.2157	No
111	BUB1	5390270	10159	0.009	-0.2298	No
112	EREG	50519 4920129	10683	0.001	-0.2583	No
113	CCNA1	6290113	10793	-0.001	-0.2642	No
114	DHRS2	4200577	10866	-0.002	-0.2681	No
115	JMY	3360242	10875	-0.003	-0.2685	No
116	BTG3	7050079	10953	-0.004	-0.2727	No
117	MDM4	4070504 4780008	11308	-0.010	-0.2920	No
118	MLF1	4570722	11426	-0.012	-0.2983	No
119	KIF2C	6940082	11750	-0.018	-0.3158	No
120	RAD9A	110300 1940632 3990390 6040014	11770	-0.018	-0.3167	No
121	CDKN1A	4050088 6400706	11801	-0.019	-0.3182	No
122	RAN	2260446 4590647	11827	-0.019	-0.3195	No
123	ANAPC10	870086 1170037 2260129	11843	-0.019	-0.3202	No
124	PAM	5290528	11865	-0.020	-0.3212	No
125	CENPF	5050088	11951	-0.022	-0.3257	No
126	SPO11	540288 4780239	12023	-0.023	-0.3295	No
127	TTK	3800129	12149	-0.026	-0.3361	No
128	MYC	380541 4670170	12234	-0.028	-0.3405	No
129	BMP4	380113	12616	-0.037	-0.3611	No
130	GAS1	2120504	12747	-0.041	-0.3679	No
131	RAD52	110093	12754	-0.041	-0.3680	No
132	GPS2	5910672	12896	-0.045	-0.3754	No
133	UHRF2	60050 840280 1340746 5080091	13083	-0.051	-0.3853	No
134	CCNK	6980048	13250	-0.057	-0.3940	No
135	EPGN	6980450	13283	-0.059	-0.3954	No
136	CHEK1	50167 1940300	13289	-0.059	-0.3953	No
137	NBN	730538 2470619 4780594	13322	-0.060	-0.3967	No
138	KIF15	610731 4070731 6520014	13416	-0.064	-0.4014	No
139	CDC23	3190593	13459	-0.066	-0.4033	No
140	PIM2	840136 5720692 7100577	13685	-0.076	-0.4152	No
141	SYCP1	2570010	13761	-0.080	-0.4188	No
142	DCTN3	6840131	13849	-0.085	-0.4230	No
143	UPF1	430164 1190750	13888	-0.087	-0.4246	No
144	ATM	3610110 4050524	13930	-0.090	-0.4263	No
145	TUBE1	2360079 6520685	13952	-0.091	-0.4269	No
146	FBXO5	2630551	13963	-0.092	-0.4269	No
147	PML	50093 2190435 2450402 3840082	13983	-0.093	-0.4274	No
148	USH1C	1570372 4230364	14222	-0.110	-0.4398	No
149	CCNT2	2100390 4150563	14235	-0.111	-0.4398	No
150	CDC25C	2570673 4760161 6520707	14375	-0.124	-0.4466	No
151	SH3BP4	3140242	14461	-0.131	-0.4505	No
152	NOTCH2	2570397	14467	-0.131	-0.4500	No
153	DDX11	6590671	14481	-0.133	-0.4500	No
154	CCNG1	870402 1500685 6110594	14508	-0.135	-0.4506	No
155	CDKN1B	3800025 6450044	14572	-0.142	-0.4532	No
156	ERN1	2360403	14585	-0.143	-0.4530	No
157	MAP2K6	1230056 2940204	14593	-0.145	-0.4526	No
158	NPM2	6040139	14613	-0.148	-0.4528	No
159	SMC3	870546 1400411 5700039 6450577	14706	-0.158	-0.4569	No
160	TGFA	1570332	14796	-0.172	-0.4607	No
161	PIN1	2970408	14858	-0.180	-0.4630	No
162	GAS7	2120358 6450494	14879	-0.183	-0.4630	No
163	GFI1B	4570131	15009	-0.204	-0.4689	No
164	RAD51L1	4010112 5860435	15068	-0.213	-0.4708	No
165	RAD51	6110450 6980280	15117	-0.225	-0.4721	No
166	UBB	4810138	15289	-0.260	-0.4800	No
167	ACVR1B	3610446 5570195	15345	-0.272	-0.4814	No
168	BRCA2	4280372	15357	-0.274	-0.4804	No
169	TUBG1	3140204	15374	-0.280	-0.4797	No
170	CDK2	130484 2260301 4010088 5050110	15400	-0.284	-0.4794	No
171	RAD17	5220739	15422	-0.288	-0.4789	No
172	LATS2	4480593 6020494	15450	-0.294	-0.4786	No
173	KIF22	1190368	15549	-0.321	-0.4821	No
174	AIF1	130332 5220017	15703	-0.369	-0.4883	No
175	GFI1	730180	15709	-0.371	-0.4865	No
176	NOLC1	2350195	15741	-0.381	-0.4859	No
177	PPP5C	3130047	15821	-0.409	-0.4879	No
178	GTF2H1	2570746 2650148	15865	-0.423	-0.4878	No
179	XRCC2	4920706	15972	-0.458	-0.4909	Yes
180	SSSCA1	1240402 780309	16008	-0.469	-0.4901	Yes
181	STRN3	1450093 6200685	16018	-0.471	-0.4879	Yes
182	APC	3850484 5860722	16027	-0.475	-0.4856	Yes
183	CUL4A	1170088 2320008 2470278	16110	-0.504	-0.4871	Yes
184	EGF	5220154	16142	-0.515	-0.4859	Yes
185	SMC4	5910240	16168	-0.524	-0.4842	Yes
186	CIT	2370601	16181	-0.528	-0.4818	Yes
187	SUGT1	1690670	16186	-0.532	-0.4789	Yes
188	HUS1	3440494 3800156	16187	-0.533	-0.4759	Yes
189	ERCC3	6900008	16234	-0.551	-0.4752	Yes
190	ING4	510632 2340619 2850176 5290706	16248	-0.554	-0.4727	Yes
191	RASSF1	2760364 4850725	16292	-0.574	-0.4717	Yes
192	RAD50	4050184 6770746	16302	-0.577	-0.4689	Yes
193	MYH10	2640673	16399	-0.614	-0.4706	Yes
194	CDC25A	3800184	16404	-0.617	-0.4672	Yes
195	CCNA2	5290075	16440	-0.634	-0.4655	Yes
196	STMN1	1990717	16449	-0.636	-0.4622	Yes
197	CCND3	380528 730500	16452	-0.637	-0.4586	Yes
198	MADD	6100725 7000088	16454	-0.638	-0.4550	Yes
199	CDC6	4570296 5360600	16457	-0.641	-0.4514	Yes
200	CDC45L	70537 3130114	16566	-0.690	-0.4533	Yes
201	NDE1	1580242 3830097	16589	-0.703	-0.4505	Yes
202	TBRG1	6110678 6520181	16623	-0.729	-0.4480	Yes
203	CCNG2	3190095	16627	-0.734	-0.4440	Yes
204	CDC37	2570537	16647	-0.742	-0.4407	Yes
205	MRE11A	3850601 4670332	16658	-0.748	-0.4369	Yes
206	CDK5R1	3870161	16667	-0.758	-0.4330	Yes
207	DLG7	3120041	16674	-0.763	-0.4289	Yes
208	CDK2AP1	2340156	16688	-0.770	-0.4252	Yes
209	ABL1	1050593 2030050 4010114	16718	-0.789	-0.4222	Yes
210	BIRC5	110408 580014 1770632	16722	-0.790	-0.4178	Yes
211	PCAF	2230161 2570369 6550451	16765	-0.812	-0.4154	Yes
212	RAD21	1990278	16835	-0.856	-0.4142	Yes
213	RAD51L3	2230609 2810286 3190008 3390053 4230168	16913	-0.906	-0.4132	Yes
214	GMNN	2630148	16925	-0.916	-0.4085	Yes
215	EIF4G2	3800575 6860184	16927	-0.918	-0.4032	Yes
216	KNTC1	430079	16964	-0.940	-0.3998	Yes
217	CDC16	1940706	17027	-0.980	-0.3975	Yes
218	CD28	1400739 4210093	17038	-0.983	-0.3924	Yes
219	PCBP4	6350722	17053	-0.991	-0.3874	Yes
220	TIPIN	1570301 2480113	17184	-1.048	-0.3884	Yes
221	PTEN	3390064	17207	-1.066	-0.3835	Yes
222	USP16	2030671	17228	-1.082	-0.3783	Yes
223	CDKN2A	4670215 4760047	17236	-1.090	-0.3724	Yes
224	ZW10	2900735 3520687	17254	-1.103	-0.3669	Yes
225	SMC1A	3060600 5700148 5890113 6370154	17283	-1.130	-0.3619	Yes
226	AURKA	780537	17299	-1.140	-0.3562	Yes
227	HSPA2	6420592	17312	-1.149	-0.3502	Yes
228	KHDRBS1	1240403 6040040	17319	-1.152	-0.3439	Yes
229	CDT1	3780682	17348	-1.186	-0.3385	Yes
230	LIG3	2940300	17350	-1.187	-0.3317	Yes
231	MPHOSPH6	5570164	17437	-1.259	-0.3292	Yes
232	CDKN1C	6520577	17535	-1.353	-0.3266	Yes
233	CCNE2	3120537	17567	-1.388	-0.3203	Yes
234	GSPT1	5420050	17593	-1.408	-0.3135	Yes
235	KIF23	5570112	17597	-1.409	-0.3056	Yes
236	PRC1	870092 5890204	17654	-1.472	-0.3001	Yes
237	ZWINT	6940670	17662	-1.481	-0.2919	Yes
238	CETN3	3170402	17668	-1.485	-0.2836	Yes
239	NDC80	4120465	17749	-1.583	-0.2788	Yes
240	ATR	6860273	17772	-1.606	-0.2708	Yes
241	PPP6C	2450670	17776	-1.613	-0.2616	Yes
242	MNAT1	730292 2350364	17785	-1.616	-0.2527	Yes
243	PTPRC	130402 5290148	17828	-1.663	-0.2454	Yes
244	CUL1	1990632	17844	-1.677	-0.2365	Yes
245	CDC7	4060546 4850041	17891	-1.718	-0.2291	Yes
246	NUSAP1	940048 3120435	17902	-1.733	-0.2196	Yes
247	ANAPC5	730164 7100685	18019	-1.862	-0.2152	Yes
248	SESN1	2120021	18080	-1.926	-0.2073	Yes
249	SKP2	360711 380093 4810368	18133	-2.012	-0.1986	Yes
250	HCFC1	2260008	18153	-2.041	-0.1878	Yes
251	CUL3	1850520	18170	-2.066	-0.1767	Yes
252	POLS	5890438	18192	-2.095	-0.1658	Yes
253	RB1	5900338	18226	-2.152	-0.1551	Yes
254	CCND1	460524 770309 3120576 6980398	18270	-2.224	-0.1446	Yes
255	TPX2	6420324	18310	-2.306	-0.1334	Yes
256	NASP	2260139 2940369 5130707	18318	-2.326	-0.1204	Yes
257	MAD2L1	4480725	18343	-2.379	-0.1080	Yes
258	ANAPC4	4540338	18344	-2.384	-0.0942	Yes
259	GTPBP4	6840332	18347	-2.393	-0.0805	Yes
260	POLE	6020538	18351	-2.398	-0.0668	Yes
261	BUB1B	1450288	18355	-2.413	-0.0530	Yes
262	RABGAP1	5050397	18380	-2.466	-0.0401	Yes
263	KPNA2	3450114	18491	-2.781	-0.0300	Yes
264	AKAP8	4210026	18559	-3.171	-0.0153	Yes
265	NCAPH	6220435	18560	-3.183	0.0031	Yes