Dataset | Set_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls #truncNotch_versus_wtNotch |
Phenotype | phenotype_truncNotch_versus_wtNotch.cls#truncNotch_versus_wtNotch |
Upregulated in class | wtNotch |
GeneSet | CAGTGTT,MIR-141,MIR-200A |
Enrichment Score (ES) | -0.61372024 |
Normalized Enrichment Score (NES) | -1.9832429 |
Nominal p-value | 0.0 |
FDR q-value | 0.0 |
FWER p-Value | 0.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | CDC42BPB | 6350037 | 891 | 1.721 | -0.0356 | No | ||
2 | ST3GAL3 | 2810601 | 1055 | 1.570 | -0.0328 | No | ||
3 | BHLHB2 | 7040603 | 1217 | 1.463 | -0.0307 | No | ||
4 | ACOT7 | 730735 1400176 7050053 | 1462 | 1.298 | -0.0343 | No | ||
5 | EPN1 | 4060725 | 1590 | 1.211 | -0.0322 | No | ||
6 | HRBL | 1850102 3830253 4780176 | 1808 | 1.075 | -0.0360 | No | ||
7 | DMWD | 770019 1690047 | 1922 | 1.019 | -0.0345 | No | ||
8 | TOP1 | 770471 4060632 6650324 | 2058 | 0.968 | -0.0347 | No | ||
9 | SON | 3120148 5860239 7040403 | 2102 | 0.945 | -0.0300 | No | ||
10 | HIC2 | 4010433 | 2150 | 0.923 | -0.0257 | No | ||
11 | PSEN1 | 130403 2030647 6100603 | 2195 | 0.902 | -0.0214 | No | ||
12 | SERF2 | 5720010 | 2333 | 0.840 | -0.0226 | No | ||
13 | STAT5A | 2680458 | 2347 | 0.833 | -0.0171 | No | ||
14 | AMPD2 | 630093 1170070 | 2490 | 0.769 | -0.0191 | No | ||
15 | DEK | 1050451 4560037 | 2600 | 0.722 | -0.0196 | No | ||
16 | FRMD4A | 2190176 | 2763 | 0.644 | -0.0236 | No | ||
17 | MDM1 | 510528 1780280 2680152 2690181 3060025 3120487 4210601 4540037 4610142 5290110 6400433 6480743 | 2985 | 0.570 | -0.0314 | No | ||
18 | TAF12 | 3710746 4920300 6180603 | 3042 | 0.547 | -0.0304 | No | ||
19 | DLC1 | 1090632 6450594 | 3099 | 0.529 | -0.0295 | No | ||
20 | SYT4 | 5080193 | 3357 | 0.448 | -0.0401 | No | ||
21 | SPRYD3 | 50403 | 3530 | 0.411 | -0.0464 | No | ||
22 | PEX5 | 1240746 1570092 2510487 | 3552 | 0.406 | -0.0446 | No | ||
23 | ATXN1 | 5550156 | 3574 | 0.402 | -0.0427 | No | ||
24 | KIF1C | 2480484 | 3984 | 0.323 | -0.0625 | No | ||
25 | MDGA1 | 1170139 | 4321 | 0.269 | -0.0788 | No | ||
26 | SOX5 | 2370576 2900167 3190128 5050528 | 4329 | 0.268 | -0.0772 | No | ||
27 | ACACA | 2490612 2680369 | 4667 | 0.226 | -0.0938 | No | ||
28 | PAPPA | 4230463 | 4896 | 0.202 | -0.1047 | No | ||
29 | CYP26B1 | 2630142 | 4998 | 0.192 | -0.1088 | No | ||
30 | GPC2 | 130647 | 5032 | 0.188 | -0.1092 | No | ||
31 | CSF3 | 2230193 6660707 | 5118 | 0.181 | -0.1125 | No | ||
32 | SIM2 | 2100044 | 5128 | 0.180 | -0.1116 | No | ||
33 | RAB38 | 2970735 | 5188 | 0.174 | -0.1135 | No | ||
34 | EPHA2 | 5890056 | 5412 | 0.156 | -0.1245 | No | ||
35 | STAT5B | 6200026 | 5493 | 0.151 | -0.1277 | No | ||
36 | STRN | 5570706 7050333 | 5577 | 0.145 | -0.1311 | No | ||
37 | KLHL18 | 4560075 | 5700 | 0.137 | -0.1367 | No | ||
38 | LRRC8A | 2510193 | 5727 | 0.135 | -0.1372 | No | ||
39 | CPD | 5360403 5860685 | 5802 | 0.130 | -0.1402 | No | ||
40 | ELAVL2 | 360181 | 5855 | 0.127 | -0.1421 | No | ||
41 | USP9X | 130435 2370735 3120338 | 5908 | 0.124 | -0.1440 | No | ||
42 | PPP2R2A | 2900014 5700575 | 6075 | 0.115 | -0.1522 | No | ||
43 | PPT2 | 2340059 3450148 | 6106 | 0.114 | -0.1529 | No | ||
44 | JUN | 840170 | 6110 | 0.114 | -0.1523 | No | ||
45 | CNP | 2260451 | 6209 | 0.108 | -0.1568 | No | ||
46 | POU4F1 | 2260315 | 6227 | 0.108 | -0.1569 | No | ||
47 | ELF2 | 1690014 2480132 3060180 3190504 | 6355 | 0.101 | -0.1631 | No | ||
48 | HOXB5 | 2900538 | 6359 | 0.101 | -0.1625 | No | ||
49 | BRUNOL6 | 6840373 | 6495 | 0.096 | -0.1691 | No | ||
50 | PTPRG | 2650524 1340022 | 6633 | 0.090 | -0.1759 | No | ||
51 | CNR1 | 6550494 6760497 | 6638 | 0.090 | -0.1754 | No | ||
52 | TGFB2 | 4920292 | 6752 | 0.085 | -0.1809 | No | ||
53 | TM9SF4 | 450538 1050093 4210112 | 6848 | 0.082 | -0.1855 | No | ||
54 | SLC17A6 | 4210576 | 6885 | 0.080 | -0.1869 | No | ||
55 | TTYH2 | 1450397 3870100 6550347 | 7505 | 0.062 | -0.2201 | No | ||
56 | DRD2 | 5890369 | 7516 | 0.061 | -0.2201 | No | ||
57 | SEMA6A | 2690138 3060021 | 7533 | 0.061 | -0.2206 | No | ||
58 | LYPLA1 | 4480373 5570551 | 7693 | 0.056 | -0.2288 | No | ||
59 | WDR26 | 1090138 | 7706 | 0.056 | -0.2290 | No | ||
60 | FOXA1 | 3710609 | 7733 | 0.056 | -0.2300 | No | ||
61 | TMEFF1 | 2680100 | 7762 | 0.055 | -0.2311 | No | ||
62 | CALCR | 1690494 | 7808 | 0.054 | -0.2332 | No | ||
63 | APBB2 | 5130403 | 7933 | 0.051 | -0.2395 | No | ||
64 | HLF | 2370113 | 7990 | 0.050 | -0.2422 | No | ||
65 | SNF1LK | 6110403 | 8053 | 0.048 | -0.2452 | No | ||
66 | B3GNT1 | 2350446 | 8149 | 0.046 | -0.2501 | No | ||
67 | LPP | 1660541 | 8155 | 0.046 | -0.2500 | No | ||
68 | PCDH9 | 2100136 | 8391 | 0.040 | -0.2625 | No | ||
69 | RBM7 | 5890348 | 8629 | 0.036 | -0.2751 | No | ||
70 | WDFY3 | 3610041 4560333 4570273 | 8643 | 0.036 | -0.2755 | No | ||
71 | LHX6 | 2360731 3360397 | 8650 | 0.036 | -0.2756 | No | ||
72 | HOXA11 | 6980133 | 8863 | 0.031 | -0.2869 | No | ||
73 | EPHA7 | 1190288 4010278 | 8903 | 0.030 | -0.2888 | No | ||
74 | CSNK1A1 | 2340427 | 8940 | 0.030 | -0.2905 | No | ||
75 | ZFR | 5910647 | 9092 | 0.027 | -0.2985 | No | ||
76 | GPM6B | 6220458 | 9126 | 0.027 | -0.3001 | No | ||
77 | ACVR2A | 6110647 | 9148 | 0.026 | -0.3011 | No | ||
78 | GRIN3A | 2370592 | 9196 | 0.025 | -0.3034 | No | ||
79 | STK35 | 2360121 | 9309 | 0.024 | -0.3093 | No | ||
80 | CHES1 | 4570121 5700162 | 9347 | 0.023 | -0.3112 | No | ||
81 | ZCCHC3 | 580438 1990035 4780278 | 9410 | 0.022 | -0.3144 | No | ||
82 | ITSN1 | 2640577 | 9525 | 0.020 | -0.3204 | No | ||
83 | ESRRG | 4010181 | 9926 | 0.013 | -0.3421 | No | ||
84 | LENG8 | 3130731 | 10009 | 0.012 | -0.3465 | No | ||
85 | DIXDC1 | 6980435 | 10047 | 0.011 | -0.3484 | No | ||
86 | SP4 | 3850176 | 10063 | 0.011 | -0.3491 | No | ||
87 | PAFAH1B2 | 5360546 6860672 | 10218 | 0.008 | -0.3574 | No | ||
88 | SPG3A | 2760091 3120170 | 10276 | 0.007 | -0.3605 | No | ||
89 | NR2C2 | 6100097 | 10393 | 0.005 | -0.3668 | No | ||
90 | PCDH8 | 2360047 4200452 | 10517 | 0.003 | -0.3734 | No | ||
91 | HNRPF | 670138 | 10939 | -0.004 | -0.3963 | No | ||
92 | SLC1A1 | 520372 6420059 | 10966 | -0.004 | -0.3977 | No | ||
93 | SLC16A7 | 2320672 | 11007 | -0.005 | -0.3998 | No | ||
94 | MYT1L | 5670369 6660403 | 11049 | -0.005 | -0.4020 | No | ||
95 | KHDRBS2 | 3520717 | 11079 | -0.006 | -0.4035 | No | ||
96 | PITX2 | 870537 2690139 | 11222 | -0.008 | -0.4112 | No | ||
97 | MMP16 | 2680139 | 11237 | -0.009 | -0.4119 | No | ||
98 | DUSP3 | 1240129 6840215 | 11397 | -0.011 | -0.4204 | No | ||
99 | CLASP2 | 2510139 | 11412 | -0.011 | -0.4211 | No | ||
100 | TRHDE | 1690068 | 11484 | -0.012 | -0.4249 | No | ||
101 | DR1 | 5860750 | 11705 | -0.017 | -0.4367 | No | ||
102 | PLAG1 | 1450142 3870139 6520039 | 11711 | -0.017 | -0.4369 | No | ||
103 | ATXN7 | 1450435 | 11753 | -0.018 | -0.4390 | No | ||
104 | CXCL12 | 580546 4150750 4570068 | 11898 | -0.020 | -0.4467 | No | ||
105 | PHYHIPL | 2360706 3840692 | 12077 | -0.024 | -0.4561 | No | ||
106 | SNAP91 | 3170056 5690520 | 12210 | -0.027 | -0.4631 | No | ||
107 | NRP2 | 4070400 5860041 6650446 | 12309 | -0.030 | -0.4682 | No | ||
108 | SRC | 580132 | 12374 | -0.031 | -0.4715 | No | ||
109 | THRB | 1780673 | 12379 | -0.031 | -0.4715 | No | ||
110 | MYRIP | 1580471 | 12483 | -0.033 | -0.4768 | No | ||
111 | MTSS1 | 780435 2370114 | 12568 | -0.035 | -0.4811 | No | ||
112 | RARB | 430139 1410138 | 12614 | -0.037 | -0.4833 | No | ||
113 | SOX11 | 610279 | 12668 | -0.038 | -0.4859 | No | ||
114 | HOXC13 | 4070722 | 12735 | -0.040 | -0.4892 | No | ||
115 | TSC1 | 1850672 | 13024 | -0.049 | -0.5045 | No | ||
116 | PTP4A1 | 130692 | 13161 | -0.054 | -0.5115 | No | ||
117 | EXOC5 | 7000711 | 13191 | -0.055 | -0.5126 | No | ||
118 | ARPC5 | 1740411 3450300 | 13268 | -0.058 | -0.5163 | No | ||
119 | TCERG1 | 2350551 4540397 5220746 | 13273 | -0.059 | -0.5161 | No | ||
120 | FGFR2 | 4670601 5570402 6940377 | 13521 | -0.069 | -0.5290 | No | ||
121 | HIPK1 | 110193 | 13682 | -0.076 | -0.5372 | No | ||
122 | RAD23B | 2190671 | 13794 | -0.082 | -0.5426 | No | ||
123 | TIAL1 | 4150048 6510605 | 13803 | -0.082 | -0.5424 | No | ||
124 | E2F3 | 50162 460180 | 13868 | -0.086 | -0.5453 | No | ||
125 | RTN4RL1 | 2630368 | 13919 | -0.089 | -0.5473 | No | ||
126 | KCNJ2 | 630019 | 13986 | -0.094 | -0.5502 | No | ||
127 | RPH3AL | 70110 | 14023 | -0.096 | -0.5514 | No | ||
128 | PCTK2 | 5700673 | 14026 | -0.096 | -0.5508 | No | ||
129 | NRXN1 | 460408 5340270 6370066 | 14110 | -0.101 | -0.5546 | No | ||
130 | STXBP1 | 360072 6220717 | 14127 | -0.103 | -0.5547 | No | ||
131 | PHLPP | 3440563 | 14257 | -0.114 | -0.5609 | No | ||
132 | CSNK2A1 | 1580577 | 14287 | -0.116 | -0.5616 | No | ||
133 | NFASC | 1940619 2470156 4590168 6840524 | 14288 | -0.116 | -0.5607 | No | ||
134 | OLFM1 | 3360161 5570066 | 14298 | -0.117 | -0.5603 | No | ||
135 | HMG20A | 4590113 | 14348 | -0.122 | -0.5621 | No | ||
136 | THRAP2 | 4920600 | 14483 | -0.134 | -0.5684 | No | ||
137 | KPNA3 | 7040088 | 14523 | -0.137 | -0.5695 | No | ||
138 | DDX5 | 940021 2630338 3440148 | 14526 | -0.137 | -0.5686 | No | ||
139 | QKI | 5220093 6130044 | 14544 | -0.139 | -0.5685 | No | ||
140 | SEPT7 | 2760685 | 14705 | -0.158 | -0.5760 | No | ||
141 | BAP1 | 3830131 | 14771 | -0.168 | -0.5783 | No | ||
142 | PBEF1 | 1090278 | 14774 | -0.168 | -0.5771 | No | ||
143 | OLIG3 | 1050603 | 14794 | -0.171 | -0.5769 | No | ||
144 | ATF5 | 5670685 | 14857 | -0.180 | -0.5789 | No | ||
145 | SLC39A9 | 3940348 | 14934 | -0.192 | -0.5816 | No | ||
146 | TTR | 4150072 | 15027 | -0.206 | -0.5851 | No | ||
147 | CBL | 6380068 | 15047 | -0.209 | -0.5846 | No | ||
148 | TNS3 | 6380242 | 15083 | -0.216 | -0.5849 | No | ||
149 | GATA6 | 1770010 | 15179 | -0.236 | -0.5883 | No | ||
150 | CALU | 2680403 3520056 4610348 5720176 6130121 | 15246 | -0.251 | -0.5900 | No | ||
151 | FBXL2 | 6450722 | 15348 | -0.273 | -0.5935 | No | ||
152 | CHD9 | 430037 2570129 5420398 | 15363 | -0.277 | -0.5922 | No | ||
153 | SLC6A9 | 2470520 | 15413 | -0.287 | -0.5927 | No | ||
154 | BICD2 | 1090411 | 15489 | -0.306 | -0.5945 | No | ||
155 | SPAG9 | 580497 2510180 4210685 | 15545 | -0.321 | -0.5951 | No | ||
156 | PTGES3 | 2190440 2680524 | 15558 | -0.323 | -0.5934 | No | ||
157 | MARCH7 | 3800020 6620168 | 15632 | -0.347 | -0.5948 | No | ||
158 | AK3L1 | 7100601 | 15694 | -0.367 | -0.5953 | No | ||
159 | YTHDF3 | 4540632 4670717 7040609 | 15856 | -0.421 | -0.6010 | No | ||
160 | FUS | 4760619 | 15876 | -0.426 | -0.5988 | No | ||
161 | MOBKL2B | 940128 | 15949 | -0.452 | -0.5994 | No | ||
162 | SLC25A3 | 670112 | 15956 | -0.455 | -0.5963 | No | ||
163 | UBE3A | 1240152 2690438 5860609 | 15982 | -0.461 | -0.5943 | No | ||
164 | BACE1 | 2650438 | 16341 | -0.592 | -0.6093 | Yes | ||
165 | FOXP1 | 6510433 | 16376 | -0.605 | -0.6067 | Yes | ||
166 | TCF12 | 3610324 7000156 | 16383 | -0.608 | -0.6025 | Yes | ||
167 | MYH10 | 2640673 | 16399 | -0.614 | -0.5987 | Yes | ||
168 | CDC25A | 3800184 | 16404 | -0.617 | -0.5943 | Yes | ||
169 | WDR44 | 130195 1050609 1570685 | 16412 | -0.621 | -0.5901 | Yes | ||
170 | GRB2 | 6650398 | 16567 | -0.690 | -0.5933 | Yes | ||
171 | MBNL1 | 2640762 7100048 | 16585 | -0.700 | -0.5890 | Yes | ||
172 | KIF3A | 5050348 6650079 | 16675 | -0.763 | -0.5882 | Yes | ||
173 | ARHGEF18 | 2120279 | 16713 | -0.785 | -0.5844 | Yes | ||
174 | STAT4 | 1660373 3130019 | 16725 | -0.792 | -0.5791 | Yes | ||
175 | YAF2 | 940053 | 16761 | -0.810 | -0.5750 | Yes | ||
176 | RTF1 | 2100735 | 16773 | -0.818 | -0.5695 | Yes | ||
177 | PPP1R15B | 2640280 5860082 | 16827 | -0.852 | -0.5660 | Yes | ||
178 | RBMS1 | 6400014 | 16951 | -0.929 | -0.5658 | Yes | ||
179 | SIPA1L2 | 4850731 | 16952 | -0.930 | -0.5589 | Yes | ||
180 | CDC14A | 4050132 | 16977 | -0.950 | -0.5531 | Yes | ||
181 | TFRC | 4050551 | 16994 | -0.963 | -0.5468 | Yes | ||
182 | DNAJC13 | 4730091 | 17225 | -1.082 | -0.5513 | Yes | ||
183 | PDCD4 | 3360403 5690110 | 17260 | -1.111 | -0.5448 | Yes | ||
184 | ARNTL | 3170463 | 17281 | -1.129 | -0.5375 | Yes | ||
185 | SIRT1 | 1190731 | 17371 | -1.201 | -0.5334 | Yes | ||
186 | MIB1 | 3800537 | 17399 | -1.228 | -0.5258 | Yes | ||
187 | ATP6V1B2 | 4060528 | 17500 | -1.319 | -0.5214 | Yes | ||
188 | ATP6V1A | 6590242 | 17513 | -1.330 | -0.5121 | Yes | ||
189 | SLC20A1 | 6420014 | 17517 | -1.332 | -0.5024 | Yes | ||
190 | SLC23A2 | 6660722 | 17562 | -1.380 | -0.4945 | Yes | ||
191 | CCNE2 | 3120537 | 17567 | -1.388 | -0.4844 | Yes | ||
192 | PLAGL2 | 1770148 | 17572 | -1.390 | -0.4743 | Yes | ||
193 | ANKFY1 | 360309 5390021 | 17617 | -1.436 | -0.4660 | Yes | ||
194 | OSBPL11 | 1770044 | 17636 | -1.455 | -0.4561 | Yes | ||
195 | YTHDF2 | 4060332 4610279 | 17690 | -1.501 | -0.4479 | Yes | ||
196 | RUNX1 | 3840711 | 17706 | -1.531 | -0.4373 | Yes | ||
197 | FKBP5 | 2190048 | 17709 | -1.535 | -0.4260 | Yes | ||
198 | ATP1B1 | 3130594 | 17741 | -1.572 | -0.4160 | Yes | ||
199 | YWHAG | 3780341 | 17748 | -1.581 | -0.4045 | Yes | ||
200 | MECP2 | 1940450 | 17781 | -1.615 | -0.3942 | Yes | ||
201 | H2AFZ | 1470168 | 17794 | -1.628 | -0.3828 | Yes | ||
202 | CSNK1G3 | 110450 | 17807 | -1.640 | -0.3712 | Yes | ||
203 | CDV3 | 1940577 | 17840 | -1.671 | -0.3605 | Yes | ||
204 | HOXB4 | 540131 | 17850 | -1.681 | -0.3485 | Yes | ||
205 | CD47 | 1850603 | 17979 | -1.820 | -0.3419 | Yes | ||
206 | BRD3 | 6130672 | 17983 | -1.826 | -0.3285 | Yes | ||
207 | MAP2K4 | 5130133 | 18021 | -1.863 | -0.3167 | Yes | ||
208 | RAP2C | 1690132 | 18028 | -1.868 | -0.3031 | Yes | ||
209 | TULP4 | 2320364 | 18067 | -1.905 | -0.2910 | Yes | ||
210 | DOLPP1 | 4780619 6400053 | 18123 | -2.000 | -0.2791 | Yes | ||
211 | CUL3 | 1850520 | 18170 | -2.066 | -0.2662 | Yes | ||
212 | MTPN | 3940167 | 18216 | -2.138 | -0.2527 | Yes | ||
213 | PRKACB | 4210170 | 18277 | -2.235 | -0.2394 | Yes | ||
214 | RABGAP1 | 5050397 | 18380 | -2.466 | -0.2266 | Yes | ||
215 | RNF44 | 5910692 | 18381 | -2.469 | -0.2082 | Yes | ||
216 | APRIN | 2810050 | 18392 | -2.494 | -0.1902 | Yes | ||
217 | ANP32E | 6510706 | 18450 | -2.630 | -0.1737 | Yes | ||
218 | ATP2A2 | 1090075 3990279 | 18452 | -2.633 | -0.1542 | Yes | ||
219 | SUPT6H | 3170082 | 18495 | -2.797 | -0.1356 | Yes | ||
220 | OGT | 2360131 4610333 | 18507 | -2.829 | -0.1152 | Yes | ||
221 | SFPQ | 4760110 | 18556 | -3.132 | -0.0945 | Yes | ||
222 | TRAM1 | 2340441 6620592 | 18565 | -3.221 | -0.0710 | Yes | ||
223 | WSB1 | 870563 | 18567 | -3.256 | -0.0468 | Yes | ||
224 | PPP2CA | 3990113 | 18569 | -3.290 | -0.0224 | Yes | ||
225 | PITPNB | 5130039 | 18571 | -3.342 | 0.0024 | Yes |