Details for gene set UVB_NHEK1

Table: GSEA Results Summary

Dataset	Set_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls #truncNotch_versus_wtNotch
Phenotype	phenotype_truncNotch_versus_wtNotch.cls#truncNotch_versus_wtNotch
Upregulated in class	wtNotch
GeneSet	UVB_NHEK1_DN
Enrichment Score (ES)	-0.5624497
Normalized Enrichment Score (NES)	-1.7828108
Nominal p-value	0.0
FDR q-value	0.04076267
FWER p-Value	0.26

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	ADRB2	3290373	91	3.156	0.0214	No
2	IGF2BP3	2810161 4230338	214	2.664	0.0371	No
3	PHC2	1430433	228	2.617	0.0582	No
4	SMAD3	6450671	421	2.238	0.0665	No
5	NAGK	730041 3170086 5890053	556	2.070	0.0765	No
6	CCNE1	110064	1324	1.384	0.0465	No
7	SART3	6060646	1592	1.210	0.0421	No
8	SSBP2	2260725 2900400 4730711	1689	1.151	0.0465	No
9	MYST3	5270500	1802	1.077	0.0494	No
10	USP24	870672 4560100	1804	1.076	0.0584	No
11	DOCK9	5080037	2140	0.930	0.0480	No
12	NFKB1	5420358	2374	0.822	0.0422	No
13	PSCD1	110113 2470592	2437	0.787	0.0454	No
14	BACH1	290195	2587	0.727	0.0434	No
15	MKI67	3440750 4480072 7050288	3171	0.502	0.0160	No
16	CEBPD	3360176	3230	0.485	0.0169	No
17	AKAP9	510184 2060195 2470136 4280048	3425	0.433	0.0100	No
18	TAF5L	5690152	3438	0.430	0.0129	No
19	SHOC2	1340064 1570546	3455	0.426	0.0156	No
20	HDHD1A	6220328	3559	0.405	0.0134	No
21	DDIT4	2570408	3564	0.404	0.0166	No
22	CNOT2	520546 2060397 4610543 5550113	4083	0.305	-0.0090	No
23	CDYL	4200142 4730397 6060400	4198	0.284	-0.0128	No
24	MEGF9	2320097	4318	0.269	-0.0170	No
25	FYN	2100468 4760520 4850687	4389	0.260	-0.0186	No
26	SH2B3	4810451 4850128	4528	0.240	-0.0241	No
27	PLK4	430162 5720110	4615	0.232	-0.0268	No
28	USP1	2760541 5690438 6220673	4671	0.225	-0.0279	No
29	NFE2L2	2810619 3390162	4711	0.221	-0.0282	No
30	DOCK4	5910102	4925	0.199	-0.0381	No
31	PER2	3120204 3390593	5062	0.186	-0.0439	No
32	AHR	4560671	5070	0.185	-0.0428	No
33	ARID5B	110403	5496	0.151	-0.0645	No
34	STRN	5570706 7050333	5577	0.145	-0.0677	No
35	ADORA2B	6860253	5866	0.126	-0.0822	No
36	RAPGEF5	1500603 3450427 6130056	5909	0.124	-0.0835	No
37	RABGAP1L	3190014 6860088	5996	0.120	-0.0871	No
38	CREB3L2	3390484	6004	0.119	-0.0865	No
39	ZNF318	5890091 6130021	6181	0.110	-0.0952	No
40	MAP3K5	6020041 6380162	6661	0.089	-0.1204	No
41	GNE	6100465	6827	0.083	-0.1287	No
42	MTM1	3060112 3170161	6909	0.079	-0.1324	No
43	TUBGCP3	4920563	7041	0.075	-0.1389	No
44	RNF13	2370021	7098	0.073	-0.1413	No
45	PAFAH1B1	4230333 6420121 6450066	7219	0.070	-0.1472	No
46	LPHN2	4480010	7442	0.063	-0.1587	No
47	CPEB3	3940164	7648	0.058	-0.1694	No
48	BRD8	1170463 2900075 4050397 6590332	7774	0.055	-0.1757	No
49	NPAS2	770670	7791	0.054	-0.1761	No
50	ARHGEF7	1690441	7815	0.054	-0.1769	No
51	NRIP1	3190039	8067	0.048	-0.1901	No
52	LPP	1660541	8155	0.046	-0.1945	No
53	MEIS1	1400575	8223	0.044	-0.1977	No
54	CBLB	3520465 4670348	8227	0.044	-0.1975	No
55	RRS1	4560551	8283	0.043	-0.2001	No
56	POGZ	870348 7040286	8639	0.036	-0.2191	No
57	WDFY3	3610041 4560333 4570273	8643	0.036	-0.2190	No
58	NCK1	6200575 6510050	8777	0.033	-0.2259	No
59	KIF2A	3990286 6130575	8816	0.032	-0.2277	No
60	SKAP2	6760500	9032	0.028	-0.2391	No
61	TIPARP	50397	9093	0.027	-0.2422	No
62	KIF11	5390139	9245	0.025	-0.2501	No
63	BDKRB2	4780706	9273	0.024	-0.2514	No
64	ZCCHC14	5900288	9387	0.022	-0.2573	No
65	POLE2	6110041	9434	0.021	-0.2597	No
66	SERTAD2	2810673 6840450	9604	0.019	-0.2687	No
67	PLEKHC1	2650066	9777	0.015	-0.2779	No
68	SLC7A1	2450193 2710241	9925	0.013	-0.2857	No
69	MTUS1	780348 4920609	9973	0.012	-0.2882	No
70	BTBD3	1980041 2510577 3190053 4200746	9984	0.012	-0.2886	No
71	XPO1	540707	10863	-0.002	-0.3362	No
72	SP3	3840338	10973	-0.004	-0.3421	No
73	WDR37	2630519 6840347	10996	-0.004	-0.3433	No
74	MTMR6	4810520	11152	-0.007	-0.3516	No
75	SMAD7	430377	11203	-0.008	-0.3543	No
76	IRS1	1190204	11519	-0.013	-0.3712	No
77	VEGFC	5910494	11571	-0.014	-0.3739	No
78	PUM2	4200441 5910446	11603	-0.015	-0.3754	No
79	ZCCHC11	3390731 5360039	11779	-0.018	-0.3848	No
80	CENPC1	610273	11790	-0.018	-0.3852	No
81	PTPN3	870369	11819	-0.019	-0.3865	No
82	MYST4	1400563 2570687 3360458 6840402	11924	-0.021	-0.3920	No
83	CENPF	5050088	11951	-0.022	-0.3932	No
84	TTC9	460463	12103	-0.025	-0.4012	No
85	MYC	380541 4670170	12234	-0.028	-0.4080	No
86	E2F5	5860575	12364	-0.031	-0.4148	No
87	NUP153	7000452	12531	-0.035	-0.4235	No
88	SPEN	2060041	12625	-0.037	-0.4282	No
89	MTIF2	2260270	12648	-0.038	-0.4291	No
90	ATRX	2340039 3610132 4210373	12753	-0.041	-0.4344	No
91	NR2F2	3170609 3310577	12988	-0.048	-0.4467	No
92	CCNB2	6510528	13046	-0.050	-0.4494	No
93	PIP5K2B	6520156 6620541	13184	-0.055	-0.4563	No
94	IRAK1BP1	610037	13376	-0.062	-0.4662	No
95	GCLC	2810731	13481	-0.067	-0.4713	No
96	FGFR2	4670601 5570402 6940377	13521	-0.069	-0.4728	No
97	SLBP	6220601	13541	-0.069	-0.4732	No
98	PRSS12	1230364 6220059	13561	-0.070	-0.4737	No
99	BCAR3	1660717	13628	-0.073	-0.4767	No
100	HMGA2	2940121 3390647 5130279 6400136	13670	-0.076	-0.4783	No
101	EFNB2	5340136	13710	-0.077	-0.4797	No
102	PIP5K3	5360112	13791	-0.082	-0.4834	No
103	PIK3R4	1990132	13835	-0.084	-0.4850	No
104	E2F3	50162 460180	13868	-0.086	-0.4860	No
105	PPP1R3C	2640170	13870	-0.086	-0.4854	No
106	RSBN1	7000487	13951	-0.091	-0.4889	No
107	TBC1D8	2340253	14153	-0.105	-0.4990	No
108	PHLPP	3440563	14257	-0.114	-0.5036	No
109	THRAP2	4920600	14483	-0.134	-0.5147	No
110	CDKN1B	3800025 6450044	14572	-0.142	-0.5183	No
111	ORC2L	1990470 6510019	14587	-0.144	-0.5178	No
112	LASS6	5890576 6520138	14625	-0.149	-0.5186	No
113	WEE1	3390070	14732	-0.160	-0.5230	No
114	TLE4	1450064 1500519	14863	-0.181	-0.5286	No
115	ZZZ3	780133 2320239 2640452 5080706 6550341	14952	-0.194	-0.5317	No
116	PPRC1	1740441	14966	-0.198	-0.5308	No
117	SLC9A6	4570091 7100097	15061	-0.212	-0.5341	No
118	NPAT	3800594 4670026	15073	-0.214	-0.5329	No
119	CLASP1	6860279	15087	-0.218	-0.5318	No
120	FNDC3A	2690097 3290044	15178	-0.236	-0.5347	No
121	NCOA3	4540195	15312	-0.265	-0.5397	No
122	CTBP2	430309 3710079	15405	-0.285	-0.5423	No
123	DTX2	4210041 7000008	15512	-0.312	-0.5455	No
124	ADCY9	5690168	15548	-0.321	-0.5447	No
125	PCF11	1240180	15652	-0.353	-0.5473	No
126	ATF2	2260348 2480441	15819	-0.409	-0.5529	No
127	DYRK1A	3190181	15866	-0.423	-0.5519	No
128	ZHX2	2900452	15981	-0.461	-0.5542	No
129	RCHY1	3800739	16134	-0.512	-0.5582	Yes
130	SMC4	5910240	16168	-0.524	-0.5556	Yes
131	PPP1R12A	4070066 4590162	16212	-0.543	-0.5534	Yes
132	FOXO1A	3120670	16243	-0.553	-0.5504	Yes
133	ZNF148	6420403	16444	-0.635	-0.5559	Yes
134	CNOT4	2320242 6760706	16547	-0.685	-0.5557	Yes
135	KLF9	3840022	16607	-0.722	-0.5529	Yes
136	BIRC2	2940435 4730020	16663	-0.757	-0.5496	Yes
137	ABL1	1050593 2030050 4010114	16718	-0.789	-0.5459	Yes
138	CENPA	5080154	16744	-0.803	-0.5406	Yes
139	KEAP1	1570121 2900546 3840576	16747	-0.805	-0.5339	Yes
140	INSIG2	3840603 5700605 6450451	16970	-0.944	-0.5381	Yes
141	ARID3A	6520605	17104	-1.006	-0.5369	Yes
142	DMTF1	5910047 1570497 2480100 6620239	17122	-1.016	-0.5293	Yes
143	REV3L	1090717	17192	-1.054	-0.5243	Yes
144	EIF2C2	770451	17196	-1.057	-0.5156	Yes
145	CREBBP	5690035 7040050	17238	-1.091	-0.5087	Yes
146	AURKA	780537	17299	-1.140	-0.5024	Yes
147	CASP8	4850154	17331	-1.166	-0.4944	Yes
148	KBTBD2	2320014	17441	-1.261	-0.4898	Yes
149	BCL7A	4560095	17468	-1.282	-0.4805	Yes
150	TAF11	5720538	17488	-1.306	-0.4706	Yes
151	SFRS2IP	730687 1500373	17499	-1.317	-0.4601	Yes
152	USP6NL	2940068	17585	-1.400	-0.4530	Yes
153	KLF7	50390	17587	-1.403	-0.4414	Yes
154	KIF23	5570112	17597	-1.409	-0.4301	Yes
155	PTK2	1780148	17646	-1.461	-0.4205	Yes
156	PRKCD	770592	17702	-1.525	-0.4107	Yes
157	TOP2A	360717	17707	-1.531	-0.3982	Yes
158	CHD1	4590048	17736	-1.565	-0.3866	Yes
159	MECP2	1940450	17781	-1.615	-0.3755	Yes
160	CUL1	1990632	17844	-1.677	-0.3648	Yes
161	SPOP	450035	17876	-1.710	-0.3522	Yes
162	DIDO1	1500601	17890	-1.717	-0.3386	Yes
163	TLK2	1170161	17903	-1.733	-0.3248	Yes
164	WDHD1	3450390	17924	-1.755	-0.3112	Yes
165	XPA	6660133	17941	-1.776	-0.2972	Yes
166	ZBTB24	4570504	17981	-1.825	-0.2841	Yes
167	FEM1B	1230110	17994	-1.837	-0.2694	Yes
168	TLK1	7100605	18049	-1.887	-0.2566	Yes
169	POLD3	6400278	18063	-1.899	-0.2414	Yes
170	TNFAIP8	2760551	18112	-1.986	-0.2274	Yes
171	ZNF638	6510112	18122	-1.998	-0.2112	Yes
172	SMC5	3440164	18179	-2.080	-0.1969	Yes
173	POLS	5890438	18192	-2.095	-0.1800	Yes
174	UBL3	6450458	18289	-2.259	-0.1664	Yes
175	ZBED4	770441	18373	-2.450	-0.1504	Yes
176	PIK3C3	6590717	18390	-2.492	-0.1304	Yes
177	CTCF	5340017	18444	-2.618	-0.1114	Yes
178	UBE2G1	2230546 5420528 7040463	18555	-3.099	-0.0915	Yes
179	ELF1	4780450	18577	-3.453	-0.0638	Yes
180	APPBP2	5130215	18579	-3.469	-0.0349	Yes
181	SMAD5	5700497	18612	-4.407	0.0002	Yes