Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls #truncNotch_versus_wtNotch |
| Phenotype | phenotype_truncNotch_versus_wtNotch.cls#truncNotch_versus_wtNotch |
| Upregulated in class | wtNotch |
| GeneSet | SANSOM_APC_LOSS5_UP |
| Enrichment Score (ES) | -0.6017911 |
| Normalized Enrichment Score (NES) | -1.7265602 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.05466366 |
| FWER p-Value | 0.563 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | SMYD5 | 6220025 | 429 | 2.228 | 0.0142 | No | ||
| 2 | GRWD1 | 6350528 | 617 | 2.004 | 0.0376 | No | ||
| 3 | SLC27A1 | 6110093 | 668 | 1.945 | 0.0675 | No | ||
| 4 | ZBTB17 | 6220082 | 731 | 1.873 | 0.0955 | No | ||
| 5 | TIAM1 | 5420288 | 1541 | 1.244 | 0.0727 | No | ||
| 6 | KCNQ1 | 1580050 6860441 | 2512 | 0.761 | 0.0331 | No | ||
| 7 | ADAM8 | 450347 5670609 | 3077 | 0.535 | 0.0116 | No | ||
| 8 | DDIT4 | 2570408 | 3564 | 0.404 | -0.0079 | No | ||
| 9 | TXNL4A | 4120286 6510242 | 3624 | 0.391 | -0.0045 | No | ||
| 10 | MDFI | 6200041 | 3765 | 0.359 | -0.0060 | No | ||
| 11 | TNFRSF19 | 3870731 6940730 | 4470 | 0.248 | -0.0399 | No | ||
| 12 | KIF20A | 2650050 | 5090 | 0.183 | -0.0702 | No | ||
| 13 | SYNCRIP | 1690195 3140113 4670279 | 5278 | 0.167 | -0.0775 | No | ||
| 14 | LAMC2 | 450692 2680041 4200059 4670148 | 5842 | 0.128 | -0.1057 | No | ||
| 15 | CD44 | 3990072 4850671 5860411 6860148 7050551 | 5857 | 0.127 | -0.1044 | No | ||
| 16 | KIF5A | 510435 | 5921 | 0.123 | -0.1057 | No | ||
| 17 | MYO1B | 770372 | 6464 | 0.097 | -0.1333 | No | ||
| 18 | PLA2G12A | 1740463 4010066 4050348 | 6774 | 0.084 | -0.1486 | No | ||
| 19 | PLA2G2A | 3190458 | 7204 | 0.070 | -0.1705 | No | ||
| 20 | CEBPZ | 2970053 2680068 | 7598 | 0.059 | -0.1908 | No | ||
| 21 | CITED1 | 2350670 | 7992 | 0.050 | -0.2111 | No | ||
| 22 | 1110014J01RIK | 1980332 | 8013 | 0.049 | -0.2114 | No | ||
| 23 | PTBP2 | 1240398 | 8341 | 0.041 | -0.2283 | No | ||
| 24 | HELLS | 4560086 4810025 | 8968 | 0.029 | -0.2616 | No | ||
| 25 | EPHB3 | 6650341 | 9595 | 0.019 | -0.2951 | No | ||
| 26 | KCND2 | 1170128 2100112 | 9607 | 0.018 | -0.2954 | No | ||
| 27 | SEMA3C | 7000020 | 9768 | 0.015 | -0.3037 | No | ||
| 28 | MMP7 | 1780497 | 10124 | 0.010 | -0.3227 | No | ||
| 29 | RIN2 | 2450184 | 10293 | 0.007 | -0.3317 | No | ||
| 30 | PKP1 | 1500433 | 10919 | -0.003 | -0.3653 | No | ||
| 31 | RNF149 | 5270494 | 10975 | -0.004 | -0.3682 | No | ||
| 32 | BTC | 3190133 | 10993 | -0.004 | -0.3691 | No | ||
| 33 | TSPAN12 | 4120010 | 11156 | -0.007 | -0.3777 | No | ||
| 34 | FAM60A | 3940092 | 11704 | -0.017 | -0.4069 | No | ||
| 35 | ZFP90 | 580121 | 12094 | -0.025 | -0.4275 | No | ||
| 36 | MYC | 380541 4670170 | 12234 | -0.028 | -0.4345 | No | ||
| 37 | ZFP97 | 520324 | 12384 | -0.031 | -0.4421 | No | ||
| 38 | CD24 | 1780091 | 13244 | -0.057 | -0.4874 | No | ||
| 39 | HDC | 4150463 | 13288 | -0.059 | -0.4888 | No | ||
| 40 | FGFR4 | 2650072 | 14069 | -0.099 | -0.5292 | No | ||
| 41 | TGFBR1 | 1400148 4280020 6550711 | 14213 | -0.109 | -0.5351 | No | ||
| 42 | OLFR91 | 6290020 | 14366 | -0.123 | -0.5412 | No | ||
| 43 | MAP4K4 | 2360059 | 14379 | -0.125 | -0.5398 | No | ||
| 44 | ORC2L | 1990470 6510019 | 14587 | -0.144 | -0.5485 | No | ||
| 45 | ZRF1 | 6020181 6510484 | 14606 | -0.147 | -0.5471 | No | ||
| 46 | UTP14A | 6590048 | 14618 | -0.148 | -0.5452 | No | ||
| 47 | 9630050M13RIK | 2370086 | 14650 | -0.151 | -0.5443 | No | ||
| 48 | FOXA2 | 540338 5860441 | 14882 | -0.184 | -0.5537 | No | ||
| 49 | ZZZ3 | 780133 2320239 2640452 5080706 6550341 | 14952 | -0.194 | -0.5542 | No | ||
| 50 | 2300002G24RIK | 2320040 | 15189 | -0.239 | -0.5629 | No | ||
| 51 | ANP32B | 940095 2450494 4200368 | 15291 | -0.261 | -0.5640 | No | ||
| 52 | REPS1 | 2320603 2510333 | 15296 | -0.261 | -0.5598 | No | ||
| 53 | CDK9 | 630707 | 15436 | -0.290 | -0.5625 | No | ||
| 54 | HK2 | 2640722 | 15620 | -0.343 | -0.5666 | No | ||
| 55 | PES1 | 2470427 | 15908 | -0.437 | -0.5748 | No | ||
| 56 | PRIM2A | 7000692 | 15959 | -0.456 | -0.5698 | No | ||
| 57 | NUP54 | 940546 2360156 4060278 | 16051 | -0.483 | -0.5667 | No | ||
| 58 | FUSIP1 | 520082 5390114 | 16369 | -0.602 | -0.5737 | No | ||
| 59 | CIRH1A | 2340372 | 16891 | -0.891 | -0.5869 | Yes | ||
| 60 | EIF4G2 | 3800575 6860184 | 16927 | -0.918 | -0.5734 | Yes | ||
| 61 | RNF4 | 580286 1400152 | 17003 | -0.968 | -0.5612 | Yes | ||
| 62 | GNL2 | 6620022 | 17235 | -1.088 | -0.5555 | Yes | ||
| 63 | IFIT2 | 4810735 | 17270 | -1.121 | -0.5385 | Yes | ||
| 64 | 4930573I19RIK | 5270402 | 17395 | -1.227 | -0.5247 | Yes | ||
| 65 | EIF1 | 5080100 | 17401 | -1.230 | -0.5044 | Yes | ||
| 66 | SOX4 | 2260091 | 17476 | -1.291 | -0.4868 | Yes | ||
| 67 | NOL5 | 580731 | 17548 | -1.368 | -0.4677 | Yes | ||
| 68 | COPS2 | 3060142 | 17767 | -1.596 | -0.4527 | Yes | ||
| 69 | HNRPAB | 540504 | 17825 | -1.660 | -0.4280 | Yes | ||
| 70 | FEM1B | 1230110 | 17994 | -1.837 | -0.4063 | Yes | ||
| 71 | PRKRIR | 2370402 | 18006 | -1.851 | -0.3759 | Yes | ||
| 72 | NCL | 2360463 4540279 | 18025 | -1.866 | -0.3457 | Yes | ||
| 73 | ETS2 | 360451 | 18058 | -1.897 | -0.3156 | Yes | ||
| 74 | NSUN2 | 2120193 | 18099 | -1.961 | -0.2850 | Yes | ||
| 75 | ETF1 | 6770075 | 18136 | -2.016 | -0.2532 | Yes | ||
| 76 | DDX21 | 6100446 | 18174 | -2.073 | -0.2205 | Yes | ||
| 77 | FTSJ3 | 3140100 | 18209 | -2.122 | -0.1868 | Yes | ||
| 78 | 1190002H23RIK | 4480128 | 18251 | -2.193 | -0.1523 | Yes | ||
| 79 | GNL3 | 4050338 4810500 | 18298 | -2.275 | -0.1167 | Yes | ||
| 80 | SRR | 1190465 3800494 | 18424 | -2.553 | -0.0807 | Yes | ||
| 81 | 2810037C14RIK | 5290575 | 18446 | -2.619 | -0.0380 | Yes | ||
| 82 | CDCA7 | 3060097 | 18500 | -2.812 | 0.0063 | Yes |
