Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls #truncNotch_versus_wtNotch |
| Phenotype | phenotype_truncNotch_versus_wtNotch.cls#truncNotch_versus_wtNotch |
| Upregulated in class | wtNotch |
| GeneSet | IDX_TSA_UP_CLUSTER3 |
| Enrichment Score (ES) | -0.60682285 |
| Normalized Enrichment Score (NES) | -1.7484517 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0438301 |
| FWER p-Value | 0.418 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | DTYMK | 2340377 | 235 | 2.603 | 0.0262 | No | ||
| 2 | TYMS | 940450 1940068 3710008 5570546 | 288 | 2.473 | 0.0603 | No | ||
| 3 | TCF19 | 6200152 | 1236 | 1.449 | 0.0309 | No | ||
| 4 | RFC5 | 3800452 6020091 | 1531 | 1.251 | 0.0337 | No | ||
| 5 | GAS6 | 4480021 | 1662 | 1.166 | 0.0441 | No | ||
| 6 | CENPK | 1740722 6200068 | 2165 | 0.917 | 0.0307 | No | ||
| 7 | ASF1B | 6590706 | 2342 | 0.835 | 0.0337 | No | ||
| 8 | ADAM8 | 450347 5670609 | 3077 | 0.535 | 0.0021 | No | ||
| 9 | MKI67 | 3440750 4480072 7050288 | 3171 | 0.502 | 0.0045 | No | ||
| 10 | MCM2 | 5050139 | 3319 | 0.459 | 0.0035 | No | ||
| 11 | RACGAP1 | 3990162 6620736 | 3408 | 0.437 | 0.0052 | No | ||
| 12 | CDC20 | 3440017 3440044 6220088 | 3513 | 0.413 | 0.0058 | No | ||
| 13 | MCM5 | 2680647 | 3531 | 0.411 | 0.0110 | No | ||
| 14 | SLCO3A1 | 1050408 2370156 6110072 | 3747 | 0.363 | 0.0049 | No | ||
| 15 | IMPDH2 | 5220138 | 4049 | 0.313 | -0.0067 | No | ||
| 16 | LRP5 | 2100397 3170484 | 4138 | 0.295 | -0.0071 | No | ||
| 17 | CX3CL1 | 3990707 | 4299 | 0.272 | -0.0116 | No | ||
| 18 | USP1 | 2760541 5690438 6220673 | 4671 | 0.225 | -0.0283 | No | ||
| 19 | KIF20A | 2650050 | 5090 | 0.183 | -0.0481 | No | ||
| 20 | MCM3 | 5570068 | 5213 | 0.172 | -0.0521 | No | ||
| 21 | PLK1 | 1780369 2640121 | 5389 | 0.159 | -0.0592 | No | ||
| 22 | NQO1 | 3450136 6840121 | 5414 | 0.156 | -0.0581 | No | ||
| 23 | LMO4 | 3800746 | 6356 | 0.101 | -0.1074 | No | ||
| 24 | BRCA1 | 4780669 | 6644 | 0.090 | -0.1215 | No | ||
| 25 | OSMR | 1990519 | 7832 | 0.053 | -0.1848 | No | ||
| 26 | IL13RA1 | 5550609 | 8059 | 0.048 | -0.1963 | No | ||
| 27 | ABCA1 | 6290156 | 8659 | 0.035 | -0.2281 | No | ||
| 28 | WNT4 | 4150619 | 8861 | 0.031 | -0.2384 | No | ||
| 29 | PTGFR | 3850373 | 8945 | 0.030 | -0.2425 | No | ||
| 30 | HELLS | 4560086 4810025 | 8968 | 0.029 | -0.2432 | No | ||
| 31 | CKS2 | 1410156 | 9063 | 0.028 | -0.2479 | No | ||
| 32 | CSRP2 | 1030575 | 9241 | 0.025 | -0.2571 | No | ||
| 33 | KIF11 | 5390139 | 9245 | 0.025 | -0.2569 | No | ||
| 34 | POLA1 | 4760541 | 9609 | 0.018 | -0.2762 | No | ||
| 35 | BUB1 | 5390270 | 10159 | 0.009 | -0.3057 | No | ||
| 36 | KLF5 | 3840348 | 11248 | -0.009 | -0.3642 | No | ||
| 37 | KIF2C | 6940082 | 11750 | -0.018 | -0.3910 | No | ||
| 38 | CCNF | 6370288 | 11830 | -0.019 | -0.3950 | No | ||
| 39 | TTK | 3800129 | 12149 | -0.026 | -0.4117 | No | ||
| 40 | CCNB2 | 6510528 | 13046 | -0.050 | -0.4593 | No | ||
| 41 | MCM10 | 4920632 | 13362 | -0.062 | -0.4754 | No | ||
| 42 | SLBP | 6220601 | 13541 | -0.069 | -0.4840 | No | ||
| 43 | HGF | 3360593 | 13659 | -0.075 | -0.4892 | No | ||
| 44 | HMGB2 | 2640603 | 13950 | -0.091 | -0.5034 | No | ||
| 45 | TOPBP1 | 6020333 | 14549 | -0.139 | -0.5336 | No | ||
| 46 | AQP1 | 450338 6020292 | 14560 | -0.140 | -0.5321 | No | ||
| 47 | EZH2 | 6130605 6380524 | 14633 | -0.150 | -0.5337 | No | ||
| 48 | RAD51 | 6110450 6980280 | 15117 | -0.225 | -0.5564 | No | ||
| 49 | FEN1 | 1770541 | 15480 | -0.302 | -0.5714 | No | ||
| 50 | KIF22 | 1190368 | 15549 | -0.321 | -0.5703 | No | ||
| 51 | SMC2 | 4810133 | 16227 | -0.548 | -0.5986 | Yes | ||
| 52 | MCM7 | 3290292 5220056 | 16282 | -0.569 | -0.5931 | Yes | ||
| 53 | BZW1 | 460270 | 16408 | -0.619 | -0.5905 | Yes | ||
| 54 | CDC6 | 4570296 5360600 | 16457 | -0.641 | -0.5836 | Yes | ||
| 55 | TRIP13 | 6860341 | 16493 | -0.659 | -0.5756 | Yes | ||
| 56 | CDC45L | 70537 3130114 | 16566 | -0.690 | -0.5692 | Yes | ||
| 57 | DLG7 | 3120041 | 16674 | -0.763 | -0.5636 | Yes | ||
| 58 | BIRC5 | 110408 580014 1770632 | 16722 | -0.790 | -0.5543 | Yes | ||
| 59 | TACC3 | 5130592 | 16768 | -0.814 | -0.5446 | Yes | ||
| 60 | TFDP1 | 1980112 | 16945 | -0.926 | -0.5402 | Yes | ||
| 61 | MAN2A1 | 6650176 | 17050 | -0.990 | -0.5311 | Yes | ||
| 62 | PRIM1 | 6420746 | 17077 | -0.999 | -0.5175 | Yes | ||
| 63 | RRM2 | 6350059 6940162 | 17182 | -1.046 | -0.5075 | Yes | ||
| 64 | INCENP | 520593 | 17229 | -1.082 | -0.4938 | Yes | ||
| 65 | AURKA | 780537 | 17299 | -1.140 | -0.4805 | Yes | ||
| 66 | CDCA8 | 2340286 6980019 | 17502 | -1.320 | -0.4717 | Yes | ||
| 67 | CCNE2 | 3120537 | 17567 | -1.388 | -0.4545 | Yes | ||
| 68 | ILF2 | 2900253 | 17637 | -1.455 | -0.4364 | Yes | ||
| 69 | PRC1 | 870092 5890204 | 17654 | -1.472 | -0.4153 | Yes | ||
| 70 | MCM4 | 2760673 5420711 | 17712 | -1.538 | -0.3954 | Yes | ||
| 71 | KIF4A | 1410465 4760070 | 17838 | -1.670 | -0.3772 | Yes | ||
| 72 | RAD51AP1 | 4050736 6370528 | 17885 | -1.714 | -0.3541 | Yes | ||
| 73 | NUSAP1 | 940048 3120435 | 17902 | -1.733 | -0.3291 | Yes | ||
| 74 | RRM1 | 4150433 | 18035 | -1.872 | -0.3082 | Yes | ||
| 75 | NASP | 2260139 2940369 5130707 | 18318 | -2.326 | -0.2887 | Yes | ||
| 76 | MAD2L1 | 4480725 | 18343 | -2.379 | -0.2545 | Yes | ||
| 77 | DCK | 6900411 | 18375 | -2.451 | -0.2195 | Yes | ||
| 78 | CCNB1 | 4590433 4780372 | 18405 | -2.518 | -0.1835 | Yes | ||
| 79 | CDCA7 | 3060097 | 18500 | -2.812 | -0.1466 | Yes | ||
| 80 | NCAPH | 6220435 | 18560 | -3.183 | -0.1022 | Yes | ||
| 81 | FIGNL1 | 6860390 | 18581 | -3.510 | -0.0509 | Yes | ||
| 82 | CSTF2 | 6040463 | 18583 | -3.529 | 0.0018 | Yes |
