Details for gene set ICHIBA

Table: GSEA Results Summary

Dataset	Set_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls #truncNotch_versus_wtNotch
Phenotype	phenotype_truncNotch_versus_wtNotch.cls#truncNotch_versus_wtNotch
Upregulated in class	truncNotch
GeneSet	ICHIBA_GVHD
Enrichment Score (ES)	0.5479271
Normalized Enrichment Score (NES)	1.6614918
Nominal p-value	0.0
FDR q-value	0.12095545
FWER p-Value	0.72

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	SLC11A1	940286 2810435 6370647	51	3.418	0.0138	Yes
2	KLF2	6860270	104	3.049	0.0258	Yes
3	PLAC8	2900019	107	3.022	0.0403	Yes
4	H2-DMA	6290463	109	3.020	0.0549	Yes
5	SCOTIN	670332 3450167 6450022	125	2.932	0.0684	Yes
6	LGALS3BP	840692	135	2.909	0.0820	Yes
7	FLOT1	1660575 1690040	160	2.827	0.0944	Yes
8	SNX12	4060026	164	2.822	0.1079	Yes
9	VEGFB	5360152	187	2.750	0.1201	Yes
10	UBE1L	6660242	226	2.625	0.1308	Yes
11	NXN	2350180	227	2.620	0.1435	Yes
12	TSPAN4	5050647	234	2.604	0.1558	Yes
13	TYROBP	2230020	258	2.536	0.1669	Yes
14	IFI35	4230739	261	2.526	0.1790	Yes
15	LGMN	3610301	300	2.444	0.1888	Yes
16	QSCN6	3120441	322	2.408	0.1993	Yes
17	GPX3	1340450	356	2.360	0.2090	Yes
18	TAP1	4050047	372	2.324	0.2195	Yes
19	CYB561	5080341	454	2.190	0.2257	Yes
20	ISG15	3170093	467	2.176	0.2356	Yes
21	CYBA	4760739	491	2.152	0.2448	Yes
22	SERPINA3G	610600	570	2.055	0.2505	Yes
23	H2-DMB1	4760026	575	2.040	0.2602	Yes
24	ELA1	3390167	590	2.030	0.2693	Yes
25	TFF3	1580129	638	1.979	0.2763	Yes
26	CRYL1	1340427	675	1.935	0.2838	Yes
27	SLC25A10	1400609	691	1.919	0.2923	Yes
28	PSMB8	2850707	692	1.918	0.3016	Yes
29	H2-AA	5290673	696	1.916	0.3107	Yes
30	PTPN1	2650056	747	1.862	0.3170	Yes
31	PLD3	510041	777	1.835	0.3244	Yes
32	PDZK1	2320128	794	1.822	0.3323	Yes
33	C1QC	5700131	815	1.798	0.3400	Yes
34	C1QA	5390687	921	1.694	0.3425	Yes
35	HES6	540411 6550504	1013	1.605	0.3453	Yes
36	CAMP	6290735	1017	1.602	0.3529	Yes
37	ALAS2	6550176	1022	1.598	0.3604	Yes
38	TAPBP	1980110	1046	1.580	0.3669	Yes
39	FBXO21	6550070	1051	1.576	0.3743	Yes
40	HBA-A1	360435	1067	1.564	0.3811	Yes
41	CCL7	2650519	1093	1.539	0.3872	Yes
42	CD68	6350450	1109	1.529	0.3938	Yes
43	S100A6	1690204	1146	1.504	0.3991	Yes
44	IRF7	1570605	1159	1.493	0.4057	Yes
45	MT2A	6860286	1227	1.456	0.4091	Yes
46	CCL5	3710397	1229	1.453	0.4161	Yes
47	IRF1	2340152 3450592 6290121 6980577	1313	1.388	0.4183	Yes
48	H2-EB1	2350079	1331	1.379	0.4241	Yes
49	SLFN2	3120114	1348	1.370	0.4299	Yes
50	CCL4	50368 430047	1374	1.353	0.4351	Yes
51	NGP	2640133	1458	1.300	0.4369	Yes
52	HP	2940551 6350068	1490	1.271	0.4413	Yes
53	HBB-B2	2450131	1529	1.252	0.4454	Yes
54	C1QB	5910292	1586	1.214	0.4482	Yes
55	LTF	6770364	1612	1.200	0.4527	Yes
56	CD53	5550162	1640	1.178	0.4569	Yes
57	S100A4	3780113	1646	1.175	0.4623	Yes
58	S100A8	70112	1731	1.127	0.4632	Yes
59	NFKBIA	1570152	1757	1.101	0.4672	Yes
60	SLPI	2120446	1761	1.098	0.4724	Yes
61	RRAS	4150609	1766	1.094	0.4775	Yes
62	S100A9	7050528	1770	1.091	0.4826	Yes
63	LCK	3360142	1776	1.087	0.4876	Yes
64	PRTN3	6900670	1882	1.035	0.4869	Yes
65	SIRPA	130465 5700332	1898	1.028	0.4911	Yes
66	CTPS	70451 1740132	1902	1.027	0.4959	Yes
67	H2-AB1	4230427	1905	1.025	0.5008	Yes
68	WARS	2570717 3290139	1954	1.005	0.5030	Yes
69	IL18BP	3450128	1969	1.000	0.5071	Yes
70	CD14	5570600	2022	0.987	0.5091	Yes
71	CLIC1	110600	2033	0.981	0.5133	Yes
72	CTSC	2230739 4670408	2042	0.976	0.5176	Yes
73	LGALS3	2120239	2082	0.958	0.5201	Yes
74	LITAF	6940671	2132	0.932	0.5220	Yes
75	D12ERTD647E	5290364	2207	0.898	0.5223	Yes
76	CFP	2100619	2274	0.868	0.5229	Yes
77	VCAM1	2900450	2305	0.852	0.5254	Yes
78	1110038F14RIK	1190075	2412	0.798	0.5235	Yes
79	ITPK1	3360056	2436	0.787	0.5261	Yes
80	COL4A1	1740575	2519	0.756	0.5253	Yes
81	SELPL	1770167	2606	0.717	0.5240	Yes
82	G6PC	430093	2610	0.716	0.5274	Yes
83	HPXN	3440114	2640	0.701	0.5292	Yes
84	PRM3	4810577	2753	0.649	0.5262	Yes
85	SAA3P	6510390	2786	0.637	0.5276	Yes
86	MT1A	4850164	2787	0.636	0.5307	Yes
87	CD7	3140465	2796	0.633	0.5333	Yes
88	FKBP11	3170575	2804	0.631	0.5360	Yes
89	TMSB10	2340484	2822	0.626	0.5381	Yes
90	LAPTM5	5550372	2834	0.622	0.5405	Yes
91	ELAC2	3440167 4730546	2853	0.614	0.5425	Yes
92	CTSE	2030292	2855	0.614	0.5454	Yes
93	PSMB10	630504 6510039	2884	0.604	0.5468	Yes
94	NOL1	4570576 4920044	2951	0.583	0.5461	Yes
95	IRGM	6110148 6660685	2991	0.567	0.5467	Yes
96	SOCS1	730139	3019	0.558	0.5479	Yes
97	IRF8	610161	3113	0.522	0.5454	No
98	NAT8	6520500	3133	0.517	0.5469	No
99	AKAP9	510184 2060195 2470136 4280048	3425	0.433	0.5331	No
100	GRN	4050239	3446	0.428	0.5341	No
101	D17H6S56E-5	4760095	3452	0.426	0.5359	No
102	EMR1	70136 1500592	3577	0.402	0.5311	No
103	MS4A6C	3870427	3640	0.387	0.5296	No
104	CCR1	3440672	3692	0.375	0.5286	No
105	CTSS	1740056	3822	0.349	0.5233	No
106	CXCL1	2690537	3826	0.349	0.5248	No
107	ITGB2	6380348	3899	0.338	0.5225	No
108	PROM1	3170537	3946	0.329	0.5216	No
109	NR1D1	2360471 770746 6590204	4046	0.313	0.5177	No
110	LPHN1	1400113 3130301	4106	0.301	0.5160	No
111	CYP8B1	2350369	4257	0.276	0.5091	No
112	MARCO	870056	4411	0.258	0.5020	No
113	CXCL9	1570673	4438	0.253	0.5018	No
114	FAS	4480112 6110040	4477	0.247	0.5010	No
115	CYBB	3870020	4810	0.210	0.4839	No
116	FCGR1	6100176	4842	0.208	0.4832	No
117	SAMHD1	2350338 5390451	4854	0.207	0.4836	No
118	MKLN1	70504 1850129	4914	0.200	0.4813	No
119	S100A11	2260064	4970	0.194	0.4793	No
120	NNMT	450471	4995	0.192	0.4789	No
121	KRT1-18	4060563	5018	0.190	0.4786	No
122	CYP2B10	3390100	5034	0.188	0.4787	No
123	IGFALS	6350195	5067	0.185	0.4779	No
124	OSBPL5	3840537 6040286	5074	0.184	0.4785	No
125	CASP1	2360546	5214	0.172	0.4717	No
126	SCD5	5690309 5220332 7040278	5347	0.161	0.4653	No
127	PLK1	1780369 2640121	5389	0.159	0.4638	No
128	PTGS1	730193 1780273 6450195	5564	0.146	0.4550	No
129	SCMH1	3190019 6770450	5715	0.136	0.4475	No
130	BMPR2	5340066 6960328	5780	0.132	0.4447	No
131	SERPINA10	2360114	6087	0.115	0.4285	No
132	ORM2	2100048	6202	0.109	0.4228	No
133	ORM3	3310128	6207	0.109	0.4232	No
134	SULT4A1	5270161	6244	0.107	0.4217	No
135	IL18R1	270546	6371	0.101	0.4153	No
136	HCK	4230592	6440	0.098	0.4121	No
137	CYP26A1	380022 2690600	6524	0.094	0.4080	No
138	SAA2	1090139	6532	0.094	0.4081	No
139	LBP	6860019	6597	0.091	0.4050	No
140	SLC1A2	2230520	6701	0.087	0.3999	No
141	PSMB9	6980471	7156	0.072	0.3754	No
142	MS4A4D	4850632	7173	0.071	0.3749	No
143	CYP2B13	5420672	7347	0.066	0.3658	No
144	CTLA2B	4210168	7428	0.064	0.3617	No
145	CD5L	4070605	7473	0.062	0.3596	No
146	SH3GL1	6110154	7731	0.056	0.3459	No
147	CYP4A10	3170288 6130131	7883	0.052	0.3379	No
148	CYP7B1	1190309	7900	0.052	0.3373	No
149	SLC26A1	2190142	7901	0.052	0.3375	No
150	GBP1	780075	7962	0.050	0.3345	No
151	ADRB3	6900072	8459	0.039	0.3077	No
152	RELN	6510037	8535	0.038	0.3037	No
153	GHR	2260156	8877	0.031	0.2853	No
154	FGL2	3170731	8905	0.030	0.2840	No
155	ELOVL2	5720064	8906	0.030	0.2841	No
156	MUP5	6770279	8978	0.029	0.2804	No
157	GBP2	50301	9124	0.027	0.2726	No
158	HSD3B2	70068 770037 4120114 4230170 5690333	9320	0.023	0.2621	No
159	CXCL10	2450408	9764	0.016	0.2380	No
160	TMSB4X	6620114	9838	0.014	0.2341	No
161	RPS6KC1	5220619	9950	0.013	0.2281	No
162	TGTP	2810138	9976	0.012	0.2268	No
163	PKLR	1170400 2470114	10067	0.011	0.2219	No
164	CCL6	6660390	10091	0.010	0.2207	No
165	KEG1	6940603	10122	0.010	0.2191	No
166	GSTM6	3940358 5670019	10221	0.008	0.2138	No
167	CAR14	1450528	10286	0.007	0.2104	No
168	SULT2A2	2650397	10623	0.002	0.1921	No
169	IL1RN	2370333	10640	0.001	0.1912	No
170	ACTL7B	460341	10752	-0.001	0.1851	No
171	PROCR	4920687	10764	-0.001	0.1846	No
172	PSCDBP	1780408	10816	-0.002	0.1818	No
173	BTG2	2350411	10911	-0.003	0.1767	No
174	LIPC	2690497	10924	-0.003	0.1760	No
175	5830411E10RIK	2940053	11031	-0.005	0.1703	No
176	DCLRE1A	5890427	11246	-0.009	0.1586	No
177	PAX3	50551	11247	-0.009	0.1587	No
178	IFI202B	4070398	11344	-0.010	0.1535	No
179	HSD17B2	3800541	11372	-0.010	0.1521	No
180	H2-D1	2190725	11374	-0.011	0.1521	No
181	IFIT3	2450278 3190113 6200113	11516	-0.013	0.1444	No
182	ZIC3	380020	11532	-0.013	0.1437	No
183	TLR6	510102 3390148	11610	-0.015	0.1396	No
184	GIMAP4	5570673 6550041	11672	-0.016	0.1363	No
185	IFIT1	5270373	11722	-0.017	0.1337	No
186	FABP1	6940035	11824	-0.019	0.1283	No
187	HAO3	6100368	11834	-0.019	0.1279	No
188	PIRA1	4120632	11885	-0.020	0.1253	No
189	HSD3B3	4570113	11927	-0.021	0.1232	No
190	CASP6	5690239 6420551	11928	-0.021	0.1233	No
191	CYP2B9	360152	12073	-0.024	0.1155	No
192	PRLR	1980647 1990097	12169	-0.026	0.1105	No
193	ODZ3	3060725 6450292	12235	-0.028	0.1071	No
194	MUP3	4480152	12289	-0.029	0.1043	No
195	A130022J15RIK	4150494	12344	-0.030	0.1015	No
196	PDK3	510484	12370	-0.031	0.1003	No
197	LIFR	3360068 3830102	12452	-0.033	0.0960	No
198	ORM1	1500563	12499	-0.034	0.0937	No
199	CES3	5050167 3290458	12501	-0.034	0.0938	No
200	KLF10	4850056	12645	-0.038	0.0862	No
201	GAS1	2120504	12747	-0.041	0.0809	No
202	CCL2	4760019	12785	-0.042	0.0791	No
203	VNN1	3940400	12855	-0.043	0.0755	No
204	SC5DL	6650390	12858	-0.044	0.0756	No
205	SERPINA6	1850707	13182	-0.055	0.0583	No
206	CRYAA	2030164	13187	-0.055	0.0583	No
207	MSR1	940538	13308	-0.060	0.0521	No
208	MCM10	4920632	13362	-0.062	0.0495	No
209	DIO1	4570279 5290112 5420148	13390	-0.063	0.0483	No
210	MUP4	670253 4560487	13527	-0.069	0.0412	No
211	H2-EA	3870301	13599	-0.072	0.0377	No
212	AVPR1A	2120300	13677	-0.076	0.0339	No
213	FPR1	3800577	13686	-0.076	0.0338	No
214	GDF5	510440	13733	-0.078	0.0317	No
215	LRG1	5690605	13813	-0.083	0.0278	No
216	UBD	5570632	13863	-0.086	0.0255	No
217	PPP1R3C	2640170	13870	-0.086	0.0256	No
218	GBP4	6520471 1980670	14113	-0.102	0.0129	No
219	OAT	540632	14188	-0.107	0.0094	No
220	CSF1R	2340110 6420408	14370	-0.124	0.0001	No
221	LY75	1990358 4590136	14412	-0.127	-0.0015	No
222	CHI3L3	2120332	14415	-0.127	-0.0010	No
223	LCP2	2680066 6650707	14482	-0.134	-0.0040	No
224	APBB1IP	4560441 4570706 6520739	14498	-0.135	-0.0041	No
225	GP49A	1940390	14518	-0.136	-0.0045	No
226	RPL22	4070070	14562	-0.141	-0.0062	No
227	ATP11A	1240717 5570603	14568	-0.141	-0.0058	No
228	PBEF1	1090278	14774	-0.168	-0.0161	No
229	CDC5L	3130446 3390025 6400204	14845	-0.177	-0.0191	No
230	MARVELD1	6110309	14866	-0.181	-0.0193	No
231	MMP12	4920070	14967	-0.198	-0.0238	No
232	NFKBIZ	2970450	14989	-0.200	-0.0240	No
233	XDH	6840446	15119	-0.225	-0.0299	No
234	GLT25D1	540088	15186	-0.238	-0.0323	No
235	PAPSS2	870113	15302	-0.263	-0.0373	No
236	NCOA3	4540195	15312	-0.265	-0.0365	No
237	NR2F6	1340239 5670239 60338 4280088	15316	-0.265	-0.0354	No
238	CD52	5910242	15525	-0.315	-0.0452	No
239	ADCY9	5690168	15548	-0.321	-0.0449	No
240	UBAP2L	4120128 6650133	15551	-0.321	-0.0434	No
241	PPP1R2	3710278 1400725	15579	-0.329	-0.0433	No
242	STX3	1190563 2640215	15580	-0.330	-0.0417	No
243	AIF1	130332 5220017	15703	-0.369	-0.0466	No
244	IL6ST	5890047	15820	-0.409	-0.0509	No
245	SNX10	3800035	15840	-0.415	-0.0499	No
246	SPTLC2	6840324 520017	15843	-0.416	-0.0480	No
247	LY86	2230093	15891	-0.433	-0.0485	No
248	HMGCS2	770725	15971	-0.458	-0.0506	No
249	LY6A	6110605	16038	-0.479	-0.0518	No
250	STAT1	6510204 6590553	16041	-0.480	-0.0496	No
251	PSME2	4850086	16165	-0.523	-0.0538	No
252	GLTP	3440603	16291	-0.573	-0.0578	No
253	1700013L23RIK	3390097	16413	-0.622	-0.0614	No
254	AIM1	2810142	16469	-0.647	-0.0613	No
255	9830147J24RIK	2690451	16561	-0.688	-0.0629	No
256	LPL	1450735 2970706	16673	-0.762	-0.0652	No
257	BIRC5	110408 580014 1770632	16722	-0.790	-0.0640	No
258	NEK9	3440402	16763	-0.811	-0.0623	No
259	PSME1	450193 4480035	16780	-0.823	-0.0591	No
260	POM121	70152	16803	-0.838	-0.0563	No
261	NCF4	610164	16816	-0.844	-0.0528	No
262	RPAP1	4670152 6450068	16817	-0.848	-0.0487	No
263	UCK1	2650398 3130113 5130725	16828	-0.853	-0.0451	No
264	IFI47	3060673	16860	-0.874	-0.0426	No
265	USP18	4010110	16968	-0.941	-0.0438	No
266	LYZS	50068 6770717	17074	-0.999	-0.0447	No
267	ACSL1	2900520	17111	-1.010	-0.0418	No
268	ICAM1	6980138	17164	-1.039	-0.0396	No
269	SMOC2	1170170	17193	-1.055	-0.0360	No
270	BC004022	3440142	17219	-1.075	-0.0321	No
271	4921506I22RIK	1340279	17398	-1.228	-0.0359	No
272	EIF1	5080100	17401	-1.230	-0.0300	No
273	FKBP5	2190048	17709	-1.535	-0.0393	No
274	MCM4	2760673 5420711	17712	-1.538	-0.0319	No
275	IQGAP1	6660494	17762	-1.591	-0.0269	No
276	ELOVL6	5340746	17800	-1.633	-0.0210	No
277	PTPRC	130402 5290148	17828	-1.663	-0.0144	No
278	EXOSC8	360427	18018	-1.862	-0.0156	No
279	1500011J06RIK	5130056	18201	-2.112	-0.0153	No
280	ATP1B3	6040128	18248	-2.191	-0.0072	No
281	TAP2	2810347	18415	-2.534	-0.0039	No
282	PKM2	6520403 70500	18547	-3.058	0.0038	No