Details for gene set HSA04110_CELL

Table: GSEA Results Summary

Dataset	Set_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls #truncNotch_versus_wtNotch
Phenotype	phenotype_truncNotch_versus_wtNotch.cls#truncNotch_versus_wtNotch
Upregulated in class	wtNotch
GeneSet	HSA04110_CELL_CYCLE
Enrichment Score (ES)	-0.5937809
Normalized Enrichment Score (NES)	-1.7593199
Nominal p-value	0.0
FDR q-value	0.042307742
FWER p-Value	0.365

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	ANAPC7	5260274	219	2.652	0.0162	No
2	SMAD3	6450671	421	2.238	0.0291	No
3	CDK4	540075 4540600	515	2.120	0.0465	No
4	MAD2L2	1240358	828	1.784	0.0485	No
5	CDC25B	6940102	1097	1.538	0.0504	No
6	CCNE1	110064	1324	1.384	0.0528	No
7	FZR1	6220504 6660670	1436	1.320	0.0608	No
8	GADD45B	2350408	2500	0.766	0.0115	No
9	MAD1L1	5700035	2622	0.712	0.0125	No
10	CDKN2C	5050750 5130148	2627	0.707	0.0197	No
11	TGFB1	1940162	2867	0.610	0.0133	No
12	GADD45A	2900717	3144	0.512	0.0038	No
13	E2F1	5360093	3237	0.483	0.0039	No
14	CDK6	4920253	3281	0.469	0.0066	No
15	CHEK2	610139 1050022	3297	0.465	0.0107	No
16	MCM2	5050139	3319	0.459	0.0144	No
17	CDC26	5570279	3374	0.444	0.0162	No
18	TP53	6130707	3380	0.442	0.0206	No
19	BUB3	3170546	3396	0.440	0.0245	No
20	CDC20	3440017 3440044 6220088	3513	0.413	0.0226	No
21	MCM5	2680647	3531	0.411	0.0260	No
22	CDKN2D	6040035	3716	0.370	0.0200	No
23	CDC14B	2320497 3360162	4035	0.314	0.0061	No
24	SFN	6290301 7510608	4330	0.268	-0.0069	No
25	PRKDC	1400072 4230541	4927	0.199	-0.0370	No
26	ANAPC11	1780601	5028	0.189	-0.0404	No
27	CDKN2B	6020040	5044	0.187	-0.0392	No
28	MCM3	5570068	5213	0.172	-0.0465	No
29	PLK1	1780369 2640121	5389	0.159	-0.0543	No
30	ANAPC2	6660438	6066	0.116	-0.0895	No
31	TGFB2	4920292	6752	0.085	-0.1256	No
32	CCNB3	3360600	7088	0.074	-0.1430	No
33	CDK7	2640451	7739	0.056	-0.1775	No
34	SMC1B	2450397	9152	0.026	-0.2535	No
35	CCND2	5340167	9898	0.014	-0.2936	No
36	BUB1	5390270	10159	0.009	-0.3075	No
37	CCNA1	6290113	10793	-0.001	-0.3417	No
38	CDKN1A	4050088 6400706	11801	-0.019	-0.3959	No
39	ANAPC10	870086 1170037 2260129	11843	-0.019	-0.3979	No
40	YWHAH	1660133 2810053	12901	-0.045	-0.4545	No
41	CCNB2	6510528	13046	-0.050	-0.4618	No
42	CHEK1	50167 1940300	13289	-0.059	-0.4742	No
43	CDC23	3190593	13459	-0.066	-0.4827	No
44	E2F3	50162 460180	13868	-0.086	-0.5038	No
45	PTTG1	520463	13883	-0.086	-0.5036	No
46	ATM	3610110 4050524	13930	-0.090	-0.5052	No
47	CDC25C	2570673 4760161 6520707	14375	-0.124	-0.5278	No
48	RBL2	580446 1400670	14429	-0.128	-0.5293	No
49	RBX1	2120010 2340047	14472	-0.132	-0.5302	No
50	CDKN1B	3800025 6450044	14572	-0.142	-0.5341	No
51	ORC2L	1990470 6510019	14587	-0.144	-0.5333	No
52	WEE1	3390070	14732	-0.160	-0.5394	No
53	YWHAE	5310435	14848	-0.178	-0.5437	No
54	ORC1L	2370328 6110390	15143	-0.230	-0.5571	No
55	GADD45G	2510142	15193	-0.240	-0.5572	No
56	CDK2	130484 2260301 4010088 5050110	15400	-0.284	-0.5654	No
57	MDM2	3450053 5080138	15723	-0.375	-0.5788	No
58	TGFB3	1070041	15914	-0.438	-0.5844	No
59	ORC4L	4230538 5550288	16081	-0.494	-0.5881	Yes
60	YWHAQ	6760524	16184	-0.532	-0.5880	Yes
61	MCM7	3290292 5220056	16282	-0.569	-0.5872	Yes
62	CDC25A	3800184	16404	-0.617	-0.5873	Yes
63	CCNA2	5290075	16440	-0.634	-0.5824	Yes
64	CCND3	380528 730500	16452	-0.637	-0.5763	Yes
65	CDC6	4570296 5360600	16457	-0.641	-0.5697	Yes
66	ORC3L	3060348	16470	-0.649	-0.5635	Yes
67	E2F2	5270609 5570377 7000465	16494	-0.660	-0.5577	Yes
68	CDC45L	70537 3130114	16566	-0.690	-0.5543	Yes
69	ABL1	1050593 2030050 4010114	16718	-0.789	-0.5541	Yes
70	YWHAZ	1230717	16788	-0.828	-0.5490	Yes
71	MCM6	60092 540181 6510110	16794	-0.831	-0.5405	Yes
72	TFDP1	1980112	16945	-0.926	-0.5388	Yes
73	CDC14A	4050132	16977	-0.950	-0.5304	Yes
74	CDC16	1940706	17027	-0.980	-0.5227	Yes
75	CDKN2A	4670215 4760047	17236	-1.090	-0.5224	Yes
76	CREBBP	5690035 7040050	17238	-1.091	-0.5109	Yes
77	GSK3B	5360348	17269	-1.119	-0.5007	Yes
78	SMC1A	3060600 5700148 5890113 6370154	17283	-1.130	-0.4894	Yes
79	CDKN1C	6520577	17535	-1.353	-0.4886	Yes
80	CCNE2	3120537	17567	-1.388	-0.4756	Yes
81	ORC5L	1940133 1940711	17603	-1.414	-0.4625	Yes
82	HDAC1	2850670	17640	-1.456	-0.4491	Yes
83	MCM4	2760673 5420711	17712	-1.538	-0.4366	Yes
84	YWHAG	3780341	17748	-1.581	-0.4218	Yes
85	ATR	6860273	17772	-1.606	-0.4060	Yes
86	SMAD2	4200592	17810	-1.643	-0.3906	Yes
87	CUL1	1990632	17844	-1.677	-0.3746	Yes
88	CDC7	4060546 4850041	17891	-1.718	-0.3589	Yes
89	ANAPC5	730164 7100685	18019	-1.862	-0.3461	Yes
90	PCNA	940754	18090	-1.941	-0.3293	Yes
91	SKP2	360711 380093 4810368	18133	-2.012	-0.3103	Yes
92	YWHAB	1740176	18212	-2.133	-0.2919	Yes
93	RB1	5900338	18226	-2.152	-0.2698	Yes
94	HDAC2	4050433	18244	-2.188	-0.2475	Yes
95	CCND1	460524 770309 3120576 6980398	18270	-2.224	-0.2253	Yes
96	CCNH	3190347	18307	-2.289	-0.2031	Yes
97	MAD2L1	4480725	18343	-2.379	-0.1798	Yes
98	ANAPC4	4540338	18344	-2.384	-0.1545	Yes
99	BUB1B	1450288	18355	-2.413	-0.1295	Yes
100	RBL1	3130372	18396	-2.502	-0.1052	Yes
101	CCNB1	4590433 4780372	18405	-2.518	-0.0789	Yes
102	ORC6L	2260592	18445	-2.619	-0.0533	Yes
103	ANAPC1	6350162	18510	-2.840	-0.0267	Yes
104	SMAD4	5670519	18548	-3.059	0.0037	Yes