Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls #truncNotch_versus_wtNotch |
| Phenotype | phenotype_truncNotch_versus_wtNotch.cls#truncNotch_versus_wtNotch |
| Upregulated in class | wtNotch |
| GeneSet | G1_TO_S_CELL_CYCLE_REACTOME |
| Enrichment Score (ES) | -0.646116 |
| Normalized Enrichment Score (NES) | -1.7790933 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.03847445 |
| FWER p-Value | 0.273 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | CDK4 | 540075 4540600 | 515 | 2.120 | 0.0150 | No | ||
| 2 | CCNE1 | 110064 | 1324 | 1.384 | -0.0007 | No | ||
| 3 | CDKN2C | 5050750 5130148 | 2627 | 0.707 | -0.0566 | No | ||
| 4 | GADD45A | 2900717 | 3144 | 0.512 | -0.0741 | No | ||
| 5 | CREB3 | 5220408 | 3200 | 0.493 | -0.0672 | No | ||
| 6 | E2F1 | 5360093 | 3237 | 0.483 | -0.0594 | No | ||
| 7 | MCM2 | 5050139 | 3319 | 0.459 | -0.0545 | No | ||
| 8 | TP53 | 6130707 | 3380 | 0.442 | -0.0488 | No | ||
| 9 | MCM5 | 2680647 | 3531 | 0.411 | -0.0486 | No | ||
| 10 | CDKN2D | 6040035 | 3716 | 0.370 | -0.0511 | No | ||
| 11 | POLA2 | 940519 | 4916 | 0.200 | -0.1117 | No | ||
| 12 | CDKN2B | 6020040 | 5044 | 0.187 | -0.1147 | No | ||
| 13 | MCM3 | 5570068 | 5213 | 0.172 | -0.1203 | No | ||
| 14 | GBA2 | 2900372 | 7067 | 0.074 | -0.2187 | No | ||
| 15 | CDK7 | 2640451 | 7739 | 0.056 | -0.2538 | No | ||
| 16 | NACA | 520326 5890673 | 8697 | 0.035 | -0.3046 | No | ||
| 17 | POLE2 | 6110041 | 9434 | 0.021 | -0.3439 | No | ||
| 18 | CCND2 | 5340167 | 9898 | 0.014 | -0.3686 | No | ||
| 19 | CREB3L4 | 1980736 | 10200 | 0.008 | -0.3846 | No | ||
| 20 | CREB3L3 | 3450471 | 10542 | 0.003 | -0.4029 | No | ||
| 21 | CCNA1 | 6290113 | 10793 | -0.001 | -0.4164 | No | ||
| 22 | MYT1 | 6770524 | 11674 | -0.016 | -0.4635 | No | ||
| 23 | CDKN1A | 4050088 6400706 | 11801 | -0.019 | -0.4699 | No | ||
| 24 | MYC | 380541 4670170 | 12234 | -0.028 | -0.4926 | No | ||
| 25 | E2F5 | 5860575 | 12364 | -0.031 | -0.4990 | No | ||
| 26 | CREB3L1 | 2350687 | 13745 | -0.079 | -0.5718 | No | ||
| 27 | E2F3 | 50162 460180 | 13868 | -0.086 | -0.5766 | No | ||
| 28 | ATM | 3610110 4050524 | 13930 | -0.090 | -0.5781 | No | ||
| 29 | E2F6 | 3120133 3850332 4070324 | 14349 | -0.122 | -0.5982 | No | ||
| 30 | CDKN1B | 3800025 6450044 | 14572 | -0.142 | -0.6073 | No | ||
| 31 | ORC2L | 1990470 6510019 | 14587 | -0.144 | -0.6051 | No | ||
| 32 | WEE1 | 3390070 | 14732 | -0.160 | -0.6097 | No | ||
| 33 | ORC1L | 2370328 6110390 | 15143 | -0.230 | -0.6271 | No | ||
| 34 | RPA2 | 2760301 5420195 | 15395 | -0.283 | -0.6350 | No | ||
| 35 | CDK2 | 130484 2260301 4010088 5050110 | 15400 | -0.284 | -0.6295 | No | ||
| 36 | CREBL1 | 1340546 | 15407 | -0.285 | -0.6240 | No | ||
| 37 | MDM2 | 3450053 5080138 | 15723 | -0.375 | -0.6334 | No | ||
| 38 | PRIM2A | 7000692 | 15959 | -0.456 | -0.6369 | Yes | ||
| 39 | ORC4L | 4230538 5550288 | 16081 | -0.494 | -0.6335 | Yes | ||
| 40 | MCM7 | 3290292 5220056 | 16282 | -0.569 | -0.6328 | Yes | ||
| 41 | CDC25A | 3800184 | 16404 | -0.617 | -0.6269 | Yes | ||
| 42 | CCND3 | 380528 730500 | 16452 | -0.637 | -0.6166 | Yes | ||
| 43 | ORC3L | 3060348 | 16470 | -0.649 | -0.6044 | Yes | ||
| 44 | E2F2 | 5270609 5570377 7000465 | 16494 | -0.660 | -0.5924 | Yes | ||
| 45 | CDC45L | 70537 3130114 | 16566 | -0.690 | -0.5823 | Yes | ||
| 46 | CCNG2 | 3190095 | 16627 | -0.734 | -0.5708 | Yes | ||
| 47 | MCM6 | 60092 540181 6510110 | 16794 | -0.831 | -0.5630 | Yes | ||
| 48 | TFDP1 | 1980112 | 16945 | -0.926 | -0.5524 | Yes | ||
| 49 | PRIM1 | 6420746 | 17077 | -0.999 | -0.5393 | Yes | ||
| 50 | CDKN2A | 4670215 4760047 | 17236 | -1.090 | -0.5259 | Yes | ||
| 51 | CDKN1C | 6520577 | 17535 | -1.353 | -0.5147 | Yes | ||
| 52 | CCNE2 | 3120537 | 17567 | -1.388 | -0.4884 | Yes | ||
| 53 | ORC5L | 1940133 1940711 | 17603 | -1.414 | -0.4618 | Yes | ||
| 54 | MCM4 | 2760673 5420711 | 17712 | -1.538 | -0.4366 | Yes | ||
| 55 | MNAT1 | 730292 2350364 | 17785 | -1.616 | -0.4079 | Yes | ||
| 56 | RPA3 | 5700136 | 17795 | -1.631 | -0.3755 | Yes | ||
| 57 | PCNA | 940754 | 18090 | -1.941 | -0.3522 | Yes | ||
| 58 | RB1 | 5900338 | 18226 | -2.152 | -0.3161 | Yes | ||
| 59 | RPA1 | 360452 | 18231 | -2.159 | -0.2728 | Yes | ||
| 60 | CCND1 | 460524 770309 3120576 6980398 | 18270 | -2.224 | -0.2300 | Yes | ||
| 61 | CCNH | 3190347 | 18307 | -2.289 | -0.1858 | Yes | ||
| 62 | POLE | 6020538 | 18351 | -2.398 | -0.1398 | Yes | ||
| 63 | RBL1 | 3130372 | 18396 | -2.502 | -0.0918 | Yes | ||
| 64 | CCNB1 | 4590433 4780372 | 18405 | -2.518 | -0.0415 | Yes | ||
| 65 | ORC6L | 2260592 | 18445 | -2.619 | 0.0092 | Yes |
