Details for gene set ET743_SARCOMA

Table: GSEA Results Summary

Dataset	Set_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls #truncNotch_versus_wtNotch
Phenotype	phenotype_truncNotch_versus_wtNotch.cls#truncNotch_versus_wtNotch
Upregulated in class	wtNotch
GeneSet	ET743_SARCOMA_DN
Enrichment Score (ES)	-0.56712043
Normalized Enrichment Score (NES)	-1.8028102
Nominal p-value	0.0
FDR q-value	0.049543656
FWER p-Value	0.186

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	WNT5B	5080162	10	4.536	0.0273	No
2	KIAA0859	510497 770722 1340687 6840711	296	2.453	0.0269	No
3	LHFPL2	450020	371	2.327	0.0372	No
4	HSPE1	3170438	526	2.106	0.0417	No
5	HIST1H4B	4210524	635	1.982	0.0481	No
6	SLC2A1	2100609	705	1.907	0.0560	No
7	HIST1H4C	5570528	721	1.886	0.0668	No
8	RBM14	5340731 5690315	822	1.791	0.0724	No
9	BAG2	2900324	925	1.693	0.0772	No
10	SNIP1	5360092	1039	1.585	0.0808	No
11	PANX1	6550632	1861	1.045	0.0427	No
12	SIRPA	130465 5700332	1898	1.028	0.0470	No
13	FAF1	2450717 2510121 4730156	1967	1.002	0.0495	No
14	TOP1	770471 4060632 6650324	2058	0.968	0.0505	No
15	SON	3120148 5860239 7040403	2102	0.945	0.0540	No
16	TARDBP	870390 2350093	2164	0.917	0.0563	No
17	MID1IP1	2570739	2176	0.910	0.0613	No
18	USP3	2060332	2271	0.870	0.0616	No
19	DNAJA2	2630253 6860358	2377	0.817	0.0609	No
20	ARFGAP1	4780364 5390358	2393	0.808	0.0650	No
21	ZDHHC16	4230390	2446	0.783	0.0670	No
22	DLG5	450215	2839	0.620	0.0495	No
23	BLZF1	630088	3211	0.491	0.0324	No
24	BUB3	3170546	3396	0.440	0.0251	No
25	PDGFB	3060440 6370008	3509	0.414	0.0216	No
26	EPS15	4200215	3537	0.410	0.0226	No
27	CLCN7	2970095	3551	0.407	0.0244	No
28	EIF3S10	1190079 3840176	3569	0.403	0.0260	No
29	PHF6	3120632 3990041	4159	0.291	-0.0042	No
30	MRPL1	430626 3130129 5220152	4223	0.280	-0.0059	No
31	EGFR	4920138 6480521	4256	0.276	-0.0059	No
32	ADSL	5570484	4387	0.261	-0.0114	No
33	FYN	2100468 4760520 4850687	4389	0.260	-0.0099	No
34	PSMA5	5390537	4404	0.258	-0.0090	No
35	LUZP1	940075 4280458 6180070	4437	0.253	-0.0092	No
36	ARPC5L	1090148	4485	0.246	-0.0102	No
37	RCC1	2480358	4488	0.246	-0.0088	No
38	PKN2	940746 2350168	4619	0.232	-0.0145	No
39	THRAP3	6180309	4753	0.216	-0.0204	No
40	HSPA8	2120315 1050132 6550746	4841	0.208	-0.0238	No
41	ANLN	1780113 2470537 6840047	5049	0.187	-0.0339	No
42	MTMR4	4540524	5056	0.186	-0.0331	No
43	UBE2C	6130017	5204	0.173	-0.0400	No
44	MCM3	5570068	5213	0.172	-0.0394	No
45	PLK1	1780369 2640121	5389	0.159	-0.0479	No
46	B4GALT5	1230692	5672	0.138	-0.0624	No
47	CTGF	4540577	5729	0.135	-0.0646	No
48	NUFIP1	6350241	6343	0.102	-0.0972	No
49	MAP3K4	5720041	6385	0.100	-0.0988	No
50	HS3ST3B1	380040	6470	0.096	-0.1028	No
51	RNF14	50402 1340041 6370687	6718	0.087	-0.1157	No
52	MRPS35	2370603 4070551	6783	0.084	-0.1186	No
53	EIF4B	5390563 5270577	6850	0.082	-0.1217	No
54	HSPA1L	4010538	7122	0.073	-0.1360	No
55	TIAM2	360195	7124	0.072	-0.1356	No
56	BIRC6	70148	7578	0.060	-0.1598	No
57	CDH11	1230133 2100180 4610110	7613	0.059	-0.1613	No
58	CDK7	2640451	7739	0.056	-0.1678	No
59	NPAS2	770670	7791	0.054	-0.1702	No
60	UBN1	5900195	7928	0.051	-0.1773	No
61	IPO7	2190746	8346	0.041	-0.1996	No
62	CXXC5	840010	8406	0.040	-0.2026	No
63	RAB5A	6520324	8472	0.039	-0.2059	No
64	JAG1	3440390	8475	0.039	-0.2058	No
65	ARHGEF2	3360577	8524	0.038	-0.2081	No
66	OSBP	5390471	8569	0.037	-0.2103	No
67	CDC42BPA	840671	8865	0.031	-0.2261	No
68	CRSP6	2940358	8953	0.029	-0.2306	No
69	FOSL1	430021	8986	0.029	-0.2322	No
70	EPS8	7050204	9057	0.028	-0.2358	No
71	KIF11	5390139	9245	0.025	-0.2458	No
72	ACSL3	3140195	9465	0.021	-0.2576	No
73	FZD1	3140215	9539	0.020	-0.2614	No
74	XRCC5	7100286	9721	0.016	-0.2712	No
75	MFAP1	6660092	9810	0.015	-0.2759	No
76	BUB1	5390270	10159	0.009	-0.2947	No
77	CFLAR	2320605 6180440	10607	0.002	-0.3189	No
78	ATG5	6200433 5360324	11032	-0.005	-0.3419	No
79	FBXL7	6620711	11362	-0.010	-0.3597	No
80	NMI	520270	11445	-0.012	-0.3641	No
81	NCOA6	1780333 6450110	11461	-0.012	-0.3648	No
82	GDI2	2370068	11546	-0.014	-0.3693	No
83	VEGFC	5910494	11571	-0.014	-0.3705	No
84	MAPKAPK5	2510601	11592	-0.015	-0.3715	No
85	TDG	2900358 2940079	11708	-0.017	-0.3777	No
86	PLAG1	1450142 3870139 6520039	11711	-0.017	-0.3777	No
87	SPRY2	5860184	11844	-0.019	-0.3847	No
88	GGPS1	840128 2320215	11961	-0.022	-0.3909	No
89	CRK	1230162 4780128	11967	-0.022	-0.3910	No
90	MYC	380541 4670170	12234	-0.028	-0.4053	No
91	MTIF2	2260270	12648	-0.038	-0.4275	No
92	SAMD4A	1170717	12807	-0.042	-0.4358	No
93	TCERG1	2350551 4540397 5220746	13273	-0.059	-0.4607	No
94	NBN	730538 2470619 4780594	13322	-0.060	-0.4629	No
95	PRKD3	5220520 5890519	13346	-0.061	-0.4638	No
96	TRIP4	630072	13408	-0.064	-0.4667	No
97	CDC23	3190593	13459	-0.066	-0.4690	No
98	RBM27	4050603	13474	-0.067	-0.4694	No
99	TRIM24	7050670	13770	-0.080	-0.4849	No
100	RAD23B	2190671	13794	-0.082	-0.4856	No
101	PTPRK	1450433 2640142	13856	-0.085	-0.4884	No
102	SFRS9	3800047	14243	-0.112	-0.5087	No
103	JMJD1C	940575 2120025	14253	-0.113	-0.5085	No
104	CSNK2A1	1580577	14287	-0.116	-0.5095	No
105	ATF1	4570142 5550095	14358	-0.123	-0.5126	No
106	CDC25C	2570673 4760161 6520707	14375	-0.124	-0.5127	No
107	CYHR1	940609 2810463 3190332 3290692 4280411	14447	-0.130	-0.5158	No
108	PSMC2	7040010	14507	-0.135	-0.5181	No
109	SSFA2	3870133	14546	-0.139	-0.5193	No
110	WEE1	3390070	14732	-0.160	-0.5284	No
111	GOPC	6620400	14775	-0.168	-0.5296	No
112	CDC5L	3130446 3390025 6400204	14845	-0.177	-0.5323	No
113	YWHAE	5310435	14848	-0.178	-0.5313	No
114	RAB6A	3840463 4780731	15031	-0.206	-0.5399	No
115	USP12	6130735 6620280	15102	-0.221	-0.5424	No
116	PAFAH2	3140451 5720593 6510014	15176	-0.235	-0.5449	No
117	FNDC3A	2690097 3290044	15178	-0.236	-0.5435	No
118	PPP1CC	6380300 2510647	15240	-0.251	-0.5453	No
119	CORO1C	4570397	15368	-0.278	-0.5505	No
120	PSMB1	2940402	15530	-0.317	-0.5573	No
121	USP8	2640347 3840451 6100672	15623	-0.344	-0.5601	No
122	ARFGEF2	5550500	15631	-0.346	-0.5584	No
123	MRPL15	360390	15720	-0.375	-0.5609	No
124	FBXL3	5910142	15764	-0.387	-0.5608	No
125	SMARCA5	6620050	15842	-0.416	-0.5624	No
126	GTF2H1	2570746 2650148	15865	-0.423	-0.5610	No
127	PRIM2A	7000692	15959	-0.456	-0.5633	No
128	JMJD2B	6350372 6400471	15991	-0.464	-0.5621	No
129	BCL2L1	1580452 4200152 5420484	16084	-0.495	-0.5641	Yes
130	SRRM2	2940746 6350253	16132	-0.512	-0.5635	Yes
131	PSME3	2810537	16141	-0.515	-0.5608	Yes
132	GABPB2	6130450 7050735	16200	-0.538	-0.5606	Yes
133	ERCC3	6900008	16234	-0.551	-0.5590	Yes
134	PSMC6	2810021	16260	-0.560	-0.5569	Yes
135	RCOR1	5360717	16331	-0.587	-0.5571	Yes
136	ZDHHC5	1690711	16359	-0.598	-0.5549	Yes
137	CCNA2	5290075	16440	-0.634	-0.5554	Yes
138	CRLF3	6620019	16549	-0.685	-0.5570	Yes
139	BIRC2	2940435 4730020	16663	-0.757	-0.5585	Yes
140	CDK5R1	3870161	16667	-0.758	-0.5540	Yes
141	STK17B	130091	16859	-0.874	-0.5590	Yes
142	FADD	2360593 4210692 6520019	16904	-0.901	-0.5559	Yes
143	EML4	5700373	16965	-0.941	-0.5534	Yes
144	MAT2A	4070026 4730079 6020280	17061	-0.995	-0.5524	Yes
145	BTG1	4200735 6040131 6200133	17083	-1.000	-0.5474	Yes
146	TXNRD1	6590446	17245	-1.098	-0.5494	Yes
147	UBE2D2	4590671 6510446	17253	-1.102	-0.5430	Yes
148	AURKA	780537	17299	-1.140	-0.5385	Yes
149	MAPK14	5290731	17315	-1.150	-0.5322	Yes
150	SUPV3L1	1170072	17329	-1.165	-0.5258	Yes
151	SIRT1	1190731	17371	-1.201	-0.5206	Yes
152	HSPH1	1690017	17447	-1.265	-0.5169	Yes
153	RBM17	870592	17448	-1.265	-0.5091	Yes
154	GTF2B	6860685	17511	-1.328	-0.5043	Yes
155	TMPO	4050494	17673	-1.489	-0.5039	Yes
156	XBP1	3840594	17677	-1.491	-0.4949	Yes
157	TOP2A	360717	17707	-1.531	-0.4871	Yes
158	ELOVL6	5340746	17800	-1.633	-0.4821	Yes
159	PPP2R5E	70671 2120056	17878	-1.710	-0.4758	Yes
160	OSBPL9	2570373	17888	-1.715	-0.4657	Yes
161	MCTS1	6130133	17980	-1.821	-0.4595	Yes
162	STAU1	2320494	18000	-1.845	-0.4492	Yes
163	TNFSF5IP1	2060095	18012	-1.858	-0.4384	Yes
164	RAP1B	3710138	18017	-1.861	-0.4272	Yes
165	NET1	2900707	18026	-1.867	-0.4161	Yes
166	SRPK2	6380341	18036	-1.872	-0.4051	Yes
167	POLD3	6400278	18063	-1.899	-0.3949	Yes
168	UBE2D3	3190452	18074	-1.915	-0.3836	Yes
169	MAP3K7	6040068	18082	-1.929	-0.3722	Yes
170	PCNA	940754	18090	-1.941	-0.3606	Yes
171	PJA2	430537	18146	-2.037	-0.3511	Yes
172	GTF2H2	5130358	18171	-2.069	-0.3397	Yes
173	DDX21	6100446	18174	-2.073	-0.3271	Yes
174	FNTA	70059	18207	-2.120	-0.3158	Yes
175	HDAC2	4050433	18244	-2.188	-0.3043	Yes
176	SLC25A17	2100369	18246	-2.189	-0.2910	Yes
177	TBK1	5690338	18268	-2.222	-0.2784	Yes
178	AOF2	2060300	18273	-2.228	-0.2650	Yes
179	PRKACB	4210170	18277	-2.235	-0.2514	Yes
180	RIPK1	3190025	18291	-2.264	-0.2382	Yes
181	CCNH	3190347	18307	-2.289	-0.2250	Yes
182	SFRS3	770315 4230593	18340	-2.375	-0.2121	Yes
183	DCK	6900411	18375	-2.451	-0.1989	Yes
184	RABGAP1	5050397	18380	-2.466	-0.1840	Yes
185	RPP14	7040014	18382	-2.470	-0.1689	Yes
186	PSMA4	4560427	18418	-2.539	-0.1552	Yes
187	DDX20	3290348	18454	-2.649	-0.1408	Yes
188	RABGGTB	3120037	18464	-2.678	-0.1249	Yes
189	RAB1A	2370671	18476	-2.727	-0.1087	Yes
190	EP400	3940722	18487	-2.757	-0.0923	Yes
191	PSMD14	5690593	18497	-2.806	-0.0756	Yes
192	OGT	2360131 4610333	18507	-2.829	-0.0587	Yes
193	CCT4	6380161	18545	-3.052	-0.0420	Yes
194	LBR	4540671	18590	-3.582	-0.0224	Yes
195	SLC4A1AP	3190576	18602	-3.866	0.0008	Yes