Dataset | Set_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls #truncNotch_versus_wtNotch |
Phenotype | phenotype_truncNotch_versus_wtNotch.cls#truncNotch_versus_wtNotch |
Upregulated in class | wtNotch |
GeneSet | ET743_SARCOMA_72HRS_DN |
Enrichment Score (ES) | -0.56937015 |
Normalized Enrichment Score (NES) | -1.8051983 |
Nominal p-value | 0.0 |
FDR q-value | 0.06010609 |
FWER p-Value | 0.18 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | WNT5B | 5080162 | 10 | 4.536 | 0.0297 | No | ||
2 | KIAA0859 | 510497 770722 1340687 6840711 | 296 | 2.453 | 0.0307 | No | ||
3 | LHFPL2 | 450020 | 371 | 2.327 | 0.0422 | No | ||
4 | GIPC1 | 4590348 5570438 5900707 | 407 | 2.263 | 0.0554 | No | ||
5 | HSPE1 | 3170438 | 526 | 2.106 | 0.0631 | No | ||
6 | SLC2A1 | 2100609 | 705 | 1.907 | 0.0662 | No | ||
7 | RBM14 | 5340731 5690315 | 822 | 1.791 | 0.0719 | No | ||
8 | BAG2 | 2900324 | 925 | 1.693 | 0.0776 | No | ||
9 | SNIP1 | 5360092 | 1039 | 1.585 | 0.0821 | No | ||
10 | FKBP1A | 2450368 | 1722 | 1.130 | 0.0527 | No | ||
11 | PANX1 | 6550632 | 1861 | 1.045 | 0.0522 | No | ||
12 | SIRPA | 130465 5700332 | 1898 | 1.028 | 0.0571 | No | ||
13 | TOP1 | 770471 4060632 6650324 | 2058 | 0.968 | 0.0549 | No | ||
14 | SON | 3120148 5860239 7040403 | 2102 | 0.945 | 0.0589 | No | ||
15 | TARDBP | 870390 2350093 | 2164 | 0.917 | 0.0617 | No | ||
16 | MID1IP1 | 2570739 | 2176 | 0.910 | 0.0672 | No | ||
17 | CHST2 | 3180682 | 2249 | 0.876 | 0.0692 | No | ||
18 | USP3 | 2060332 | 2271 | 0.870 | 0.0738 | No | ||
19 | DNAJA2 | 2630253 6860358 | 2377 | 0.817 | 0.0736 | No | ||
20 | ARFGAP1 | 4780364 5390358 | 2393 | 0.808 | 0.0782 | No | ||
21 | ZDHHC16 | 4230390 | 2446 | 0.783 | 0.0806 | No | ||
22 | DLG5 | 450215 | 2839 | 0.620 | 0.0635 | No | ||
23 | BLZF1 | 630088 | 3211 | 0.491 | 0.0467 | No | ||
24 | BUB3 | 3170546 | 3396 | 0.440 | 0.0396 | No | ||
25 | PDGFB | 3060440 6370008 | 3509 | 0.414 | 0.0363 | No | ||
26 | EPS15 | 4200215 | 3537 | 0.410 | 0.0376 | No | ||
27 | CLCN7 | 2970095 | 3551 | 0.407 | 0.0396 | No | ||
28 | EIF3S10 | 1190079 3840176 | 3569 | 0.403 | 0.0414 | No | ||
29 | MRPL1 | 430626 3130129 5220152 | 4223 | 0.280 | 0.0078 | No | ||
30 | ADSL | 5570484 | 4387 | 0.261 | 0.0008 | No | ||
31 | PSMA5 | 5390537 | 4404 | 0.258 | 0.0016 | No | ||
32 | FAS | 4480112 6110040 | 4477 | 0.247 | -0.0006 | No | ||
33 | RCC1 | 2480358 | 4488 | 0.246 | 0.0005 | No | ||
34 | IL1RL1 | 3990224 6020347 | 4592 | 0.235 | -0.0036 | No | ||
35 | THRAP3 | 6180309 | 4753 | 0.216 | -0.0108 | No | ||
36 | SEH1L | 4590563 | 4839 | 0.208 | -0.0140 | No | ||
37 | HSPA8 | 2120315 1050132 6550746 | 4841 | 0.208 | -0.0127 | No | ||
38 | PAPPA | 4230463 | 4896 | 0.202 | -0.0142 | No | ||
39 | ANLN | 1780113 2470537 6840047 | 5049 | 0.187 | -0.0212 | No | ||
40 | MTMR4 | 4540524 | 5056 | 0.186 | -0.0203 | No | ||
41 | UBE2C | 6130017 | 5204 | 0.173 | -0.0271 | No | ||
42 | MCM3 | 5570068 | 5213 | 0.172 | -0.0264 | No | ||
43 | B4GALT5 | 1230692 | 5672 | 0.138 | -0.0503 | No | ||
44 | CTGF | 4540577 | 5729 | 0.135 | -0.0525 | No | ||
45 | NUFIP1 | 6350241 | 6343 | 0.102 | -0.0850 | No | ||
46 | HS3ST3B1 | 380040 | 6470 | 0.096 | -0.0912 | No | ||
47 | RNF14 | 50402 1340041 6370687 | 6718 | 0.087 | -0.1040 | No | ||
48 | EIF4B | 5390563 5270577 | 6850 | 0.082 | -0.1105 | No | ||
49 | HSPA1L | 4010538 | 7122 | 0.073 | -0.1247 | No | ||
50 | TIAM2 | 360195 | 7124 | 0.072 | -0.1243 | No | ||
51 | CPT1A | 6350093 | 7308 | 0.067 | -0.1338 | No | ||
52 | BIRC6 | 70148 | 7578 | 0.060 | -0.1480 | No | ||
53 | CDH11 | 1230133 2100180 4610110 | 7613 | 0.059 | -0.1494 | No | ||
54 | CDK7 | 2640451 | 7739 | 0.056 | -0.1558 | No | ||
55 | IPO7 | 2190746 | 8346 | 0.041 | -0.1884 | No | ||
56 | CXXC5 | 840010 | 8406 | 0.040 | -0.1913 | No | ||
57 | RAB5A | 6520324 | 8472 | 0.039 | -0.1946 | No | ||
58 | JAG1 | 3440390 | 8475 | 0.039 | -0.1944 | No | ||
59 | ARHGEF2 | 3360577 | 8524 | 0.038 | -0.1968 | No | ||
60 | CRSP6 | 2940358 | 8953 | 0.029 | -0.2198 | No | ||
61 | FOSL1 | 430021 | 8986 | 0.029 | -0.2213 | No | ||
62 | EPS8 | 7050204 | 9057 | 0.028 | -0.2249 | No | ||
63 | ACSL3 | 3140195 | 9465 | 0.021 | -0.2469 | No | ||
64 | FZD1 | 3140215 | 9539 | 0.020 | -0.2507 | No | ||
65 | XRCC5 | 7100286 | 9721 | 0.016 | -0.2604 | No | ||
66 | MFAP1 | 6660092 | 9810 | 0.015 | -0.2651 | No | ||
67 | BUB1 | 5390270 | 10159 | 0.009 | -0.2839 | No | ||
68 | MRPL35 | 1990671 | 10578 | 0.002 | -0.3065 | No | ||
69 | CFLAR | 2320605 6180440 | 10607 | 0.002 | -0.3080 | No | ||
70 | ATG5 | 6200433 5360324 | 11032 | -0.005 | -0.3309 | No | ||
71 | FBXL7 | 6620711 | 11362 | -0.010 | -0.3487 | No | ||
72 | NCOA6 | 1780333 6450110 | 11461 | -0.012 | -0.3539 | No | ||
73 | GDI2 | 2370068 | 11546 | -0.014 | -0.3584 | No | ||
74 | VEGFC | 5910494 | 11571 | -0.014 | -0.3596 | No | ||
75 | TDG | 2900358 2940079 | 11708 | -0.017 | -0.3669 | No | ||
76 | PLAG1 | 1450142 3870139 6520039 | 11711 | -0.017 | -0.3669 | No | ||
77 | SPRY2 | 5860184 | 11844 | -0.019 | -0.3739 | No | ||
78 | GGPS1 | 840128 2320215 | 11961 | -0.022 | -0.3800 | No | ||
79 | CRK | 1230162 4780128 | 11967 | -0.022 | -0.3802 | No | ||
80 | MYC | 380541 4670170 | 12234 | -0.028 | -0.3944 | No | ||
81 | MTIF2 | 2260270 | 12648 | -0.038 | -0.4165 | No | ||
82 | LYN | 6040600 | 13008 | -0.048 | -0.4356 | No | ||
83 | TCERG1 | 2350551 4540397 5220746 | 13273 | -0.059 | -0.4496 | No | ||
84 | PRKD3 | 5220520 5890519 | 13346 | -0.061 | -0.4531 | No | ||
85 | CDC23 | 3190593 | 13459 | -0.066 | -0.4587 | No | ||
86 | RBM27 | 4050603 | 13474 | -0.067 | -0.4590 | No | ||
87 | SFRS9 | 3800047 | 14243 | -0.112 | -0.4999 | No | ||
88 | CDC25C | 2570673 4760161 6520707 | 14375 | -0.124 | -0.5062 | No | ||
89 | CYHR1 | 940609 2810463 3190332 3290692 4280411 | 14447 | -0.130 | -0.5091 | No | ||
90 | SSFA2 | 3870133 | 14546 | -0.139 | -0.5135 | No | ||
91 | WEE1 | 3390070 | 14732 | -0.160 | -0.5225 | No | ||
92 | GOPC | 6620400 | 14775 | -0.168 | -0.5236 | No | ||
93 | CDC5L | 3130446 3390025 6400204 | 14845 | -0.177 | -0.5262 | No | ||
94 | USP12 | 6130735 6620280 | 15102 | -0.221 | -0.5386 | No | ||
95 | FNDC3A | 2690097 3290044 | 15178 | -0.236 | -0.5411 | No | ||
96 | PPP1CC | 6380300 2510647 | 15240 | -0.251 | -0.5427 | No | ||
97 | CORO1C | 4570397 | 15368 | -0.278 | -0.5477 | No | ||
98 | PSMB1 | 2940402 | 15530 | -0.317 | -0.5543 | No | ||
99 | ARFGEF2 | 5550500 | 15631 | -0.346 | -0.5575 | No | ||
100 | SNRPG | 2340551 | 15653 | -0.353 | -0.5562 | No | ||
101 | MRPL15 | 360390 | 15720 | -0.375 | -0.5573 | No | ||
102 | FBXL3 | 5910142 | 15764 | -0.387 | -0.5571 | No | ||
103 | SMARCA5 | 6620050 | 15842 | -0.416 | -0.5585 | No | ||
104 | GTF2H1 | 2570746 2650148 | 15865 | -0.423 | -0.5568 | No | ||
105 | GCNT1 | 940129 1780215 2370253 | 15869 | -0.424 | -0.5542 | No | ||
106 | PRIM2A | 7000692 | 15959 | -0.456 | -0.5559 | No | ||
107 | JMJD2B | 6350372 6400471 | 15991 | -0.464 | -0.5545 | No | ||
108 | BCL2L1 | 1580452 4200152 5420484 | 16084 | -0.495 | -0.5562 | No | ||
109 | GABPB2 | 6130450 7050735 | 16200 | -0.538 | -0.5588 | No | ||
110 | ERCC3 | 6900008 | 16234 | -0.551 | -0.5569 | No | ||
111 | PSMC6 | 2810021 | 16260 | -0.560 | -0.5546 | No | ||
112 | ZDHHC5 | 1690711 | 16359 | -0.598 | -0.5559 | No | ||
113 | RPS7 | 6860113 | 16401 | -0.615 | -0.5540 | No | ||
114 | CCNA2 | 5290075 | 16440 | -0.634 | -0.5518 | No | ||
115 | BIRC2 | 2940435 4730020 | 16663 | -0.757 | -0.5588 | No | ||
116 | STK17B | 130091 | 16859 | -0.874 | -0.5635 | Yes | ||
117 | FADD | 2360593 4210692 6520019 | 16904 | -0.901 | -0.5599 | Yes | ||
118 | EML4 | 5700373 | 16965 | -0.941 | -0.5569 | Yes | ||
119 | ACTL6A | 5220543 6290541 2450093 4590332 5270722 | 17037 | -0.982 | -0.5542 | Yes | ||
120 | MAT2A | 4070026 4730079 6020280 | 17061 | -0.995 | -0.5488 | Yes | ||
121 | GNL2 | 6620022 | 17235 | -1.088 | -0.5509 | Yes | ||
122 | TXNRD1 | 6590446 | 17245 | -1.098 | -0.5440 | Yes | ||
123 | UBE2D2 | 4590671 6510446 | 17253 | -1.102 | -0.5370 | Yes | ||
124 | MAPK14 | 5290731 | 17315 | -1.150 | -0.5327 | Yes | ||
125 | SUPV3L1 | 1170072 | 17329 | -1.165 | -0.5256 | Yes | ||
126 | SIRT1 | 1190731 | 17371 | -1.201 | -0.5198 | Yes | ||
127 | EMP1 | 4120438 | 17427 | -1.248 | -0.5144 | Yes | ||
128 | HSPH1 | 1690017 | 17447 | -1.265 | -0.5070 | Yes | ||
129 | RBM17 | 870592 | 17448 | -1.265 | -0.4986 | Yes | ||
130 | GTF2B | 6860685 | 17511 | -1.328 | -0.4931 | Yes | ||
131 | TMPO | 4050494 | 17673 | -1.489 | -0.4918 | Yes | ||
132 | XBP1 | 3840594 | 17677 | -1.491 | -0.4820 | Yes | ||
133 | TOP2A | 360717 | 17707 | -1.531 | -0.4734 | Yes | ||
134 | ELOVL6 | 5340746 | 17800 | -1.633 | -0.4675 | Yes | ||
135 | PPP2R5E | 70671 2120056 | 17878 | -1.710 | -0.4602 | Yes | ||
136 | PPP2CB | 5570593 | 17893 | -1.724 | -0.4495 | Yes | ||
137 | EXOC2 | 3190132 | 17967 | -1.799 | -0.4414 | Yes | ||
138 | MCTS1 | 6130133 | 17980 | -1.821 | -0.4299 | Yes | ||
139 | TNFSF5IP1 | 2060095 | 18012 | -1.858 | -0.4192 | Yes | ||
140 | RAP1B | 3710138 | 18017 | -1.861 | -0.4070 | Yes | ||
141 | SRPK2 | 6380341 | 18036 | -1.872 | -0.3954 | Yes | ||
142 | POLD3 | 6400278 | 18063 | -1.899 | -0.3842 | Yes | ||
143 | UBE2D3 | 3190452 | 18074 | -1.915 | -0.3719 | Yes | ||
144 | MAP3K7 | 6040068 | 18082 | -1.929 | -0.3594 | Yes | ||
145 | PCNA | 940754 | 18090 | -1.941 | -0.3468 | Yes | ||
146 | PSMD12 | 730044 | 18128 | -2.007 | -0.3354 | Yes | ||
147 | PJA2 | 430537 | 18146 | -2.037 | -0.3228 | Yes | ||
148 | GTF2H2 | 5130358 | 18171 | -2.069 | -0.3102 | Yes | ||
149 | DDX21 | 6100446 | 18174 | -2.073 | -0.2965 | Yes | ||
150 | FNTA | 70059 | 18207 | -2.120 | -0.2841 | Yes | ||
151 | HDAC2 | 4050433 | 18244 | -2.188 | -0.2714 | Yes | ||
152 | SLC25A17 | 2100369 | 18246 | -2.189 | -0.2569 | Yes | ||
153 | TBK1 | 5690338 | 18268 | -2.222 | -0.2432 | Yes | ||
154 | RIPK1 | 3190025 | 18291 | -2.264 | -0.2292 | Yes | ||
155 | CCNH | 3190347 | 18307 | -2.289 | -0.2148 | Yes | ||
156 | RABGAP1 | 5050397 | 18380 | -2.466 | -0.2022 | Yes | ||
157 | PIK3C3 | 6590717 | 18390 | -2.492 | -0.1860 | Yes | ||
158 | PSMA4 | 4560427 | 18418 | -2.539 | -0.1706 | Yes | ||
159 | ATP2A2 | 1090075 3990279 | 18452 | -2.633 | -0.1548 | Yes | ||
160 | DDX20 | 3290348 | 18454 | -2.649 | -0.1371 | Yes | ||
161 | RABGGTB | 3120037 | 18464 | -2.678 | -0.1197 | Yes | ||
162 | RAB1A | 2370671 | 18476 | -2.727 | -0.1021 | Yes | ||
163 | OGT | 2360131 4610333 | 18507 | -2.829 | -0.0849 | Yes | ||
164 | CCT4 | 6380161 | 18545 | -3.052 | -0.0665 | Yes | ||
165 | SMAD4 | 5670519 | 18548 | -3.059 | -0.0462 | Yes | ||
166 | LBR | 4540671 | 18590 | -3.582 | -0.0245 | Yes | ||
167 | SLC4A1AP | 3190576 | 18602 | -3.866 | 0.0008 | Yes |