DatasetSet_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls
#truncNotch_versus_wtNotch
Phenotypephenotype_truncNotch_versus_wtNotch.cls#truncNotch_versus_wtNotch
Upregulated in classwtNotch
GeneSetET743_SARCOMA_48HRS_DN
Enrichment Score (ES)-0.5673441
Normalized Enrichment Score (NES)-1.7431602
Nominal p-value0.0
FDR q-value0.044970233
FWER p-Value0.446
Table: GSEA Results Summary



Fig 1: Enrichment plot: ET743_SARCOMA_48HRS_DN   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEDESCRIPTION
(from dataset)
GENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1WNT5B5080162104.5360.0347No
2KIAA0859510497 770722 1340687 68407112962.4530.0383No
3LHFPL24500203712.3270.0524No
4HSPE131704385262.1060.0605No
5SLC2A121006097051.9070.0656No
6RBM145340731 56903158221.7910.0733No
7BAG229003249251.6930.0809No
8SNIP1536009210391.5850.0871No
9PANX1655063218611.0450.0508No
10SIRPA130465 570033218981.0280.0569No
11TOP1770471 4060632 665032420580.9680.0558No
12SON3120148 5860239 704040321020.9450.0608No
13TARDBP870390 235009321640.9170.0646No
14MID1IP1257073921760.9100.0711No
15USP3206033222710.8700.0728No
16DNAJA22630253 686035823770.8170.0734No
17ARFGAP14780364 539035823930.8080.0789No
18ZDHHC16423039024460.7830.0822No
19DLG545021528390.6200.0658No
20BLZF163008832110.4910.0495No
21BUB3317054633960.4400.0430No
22PDGFB3060440 637000835090.4140.0401No
23CLCN7297009535510.4070.0411No
24EIF3S101190079 384017635690.4030.0433No
25MRPL1430626 3130129 522015242230.2800.0101No
26ADSL557048443870.2610.0033No
27PSMA5539053744040.2580.0044No
28THRAP3618030947530.216-0.0127No
29HSPA82120315 1050132 655074648410.208-0.0158No
30MTMR4454052450560.186-0.0259No
31UBE2C613001752040.173-0.0326No
32MCM3557006852130.172-0.0316No
33PLK11780369 264012153890.159-0.0399No
34B4GALT5123069256720.138-0.0541No
35CTGF454057757290.135-0.0561No
36NUFIP1635024163430.102-0.0884No
37HS3ST3B138004064700.096-0.0945No
38RNF1450402 1340041 637068767180.087-0.1072No
39HSPA1L401053871220.073-0.1285No
40TIAM236019571240.072-0.1279No
41BIRC67014875780.060-0.1520No
42CDH111230133 2100180 461011076130.059-0.1534No
43CDK7264045177390.056-0.1597No
44UBN1590019579280.051-0.1695No
45IPO7219074683460.041-0.1917No
46CXXC584001084060.040-0.1946No
47RAB5A652032484720.039-0.1978No
48CDC42BPA84067188650.031-0.2188No
49CRSP6294035889530.029-0.2233No
50FOSL143002189860.029-0.2248No
51EPS8705020490570.028-0.2284No
52KIF11539013992450.025-0.2383No
53FZD1314021595390.020-0.2540No
54MFAP1666009298100.015-0.2685No
55BUB15390270101590.009-0.2873No
56CFLAR2320605 6180440106070.002-0.3115No
57ATG56200433 536032411032-0.005-0.3344No
58FBXL7662071111362-0.010-0.3521No
59NMI52027011445-0.012-0.3565No
60NCOA61780333 645011011461-0.012-0.3572No
61VEGFC591049411571-0.014-0.3630No
62MAPKAPK5251060111592-0.015-0.3639No
63TDG2900358 294007911708-0.017-0.3700No
64PLAG11450142 3870139 652003911711-0.017-0.3700No
65MTIF2226027012648-0.038-0.4204No
66TCERG12350551 4540397 522074613273-0.059-0.4537No
67NBN730538 2470619 478059413322-0.060-0.4558No
68TRIP463007213408-0.064-0.4599No
69CDC23319059313459-0.066-0.4621No
70RBM27405060313474-0.067-0.4624No
71SFRS9380004714243-0.112-0.5031No
72JMJD1C940575 212002514253-0.113-0.5027No
73CSNK2A1158057714287-0.116-0.5035No
74ATF14570142 555009514358-0.123-0.5064No
75CYHR1940609 2810463 3190332 3290692 428041114447-0.130-0.5101No
76PSMC2704001014507-0.135-0.5123No
77SSFA2387013314546-0.139-0.5133No
78GOPC662040014775-0.168-0.5243No
79CDC5L3130446 3390025 640020414845-0.177-0.5266No
80USP126130735 662028015102-0.221-0.5388No
81PAFAH23140451 5720593 651001415176-0.235-0.5409No
82FNDC3A2690097 329004415178-0.236-0.5391No
83PPP1CC6380300 251064715240-0.251-0.5405No
84PSMB1294040215530-0.317-0.5537No
85MRPL1536039015720-0.375-0.5610No
86FBXL3591014215764-0.387-0.5603No
87SMARCA5662005015842-0.416-0.5612No
88GTF2H12570746 265014815865-0.423-0.5591No
89PRIM2A700069215959-0.456-0.5606No
90BCL2L11580452 4200152 542048416084-0.495-0.5635Yes
91PSME3281053716141-0.515-0.5625Yes
92GABPB26130450 705073516200-0.538-0.5615Yes
93ERCC3690000816234-0.551-0.5590Yes
94PSMC6281002116260-0.560-0.5560Yes
95RCOR1536071716331-0.587-0.5552Yes
96ZDHHC5169071116359-0.598-0.5520Yes
97CCNA2529007516440-0.634-0.5514Yes
98CRLF3662001916549-0.685-0.5520Yes
99BIRC22940435 473002016663-0.757-0.5522Yes
100STK17B13009116859-0.874-0.5560Yes
101EML4570037316965-0.941-0.5543Yes
102MAT2A4070026 4730079 602028017061-0.995-0.5517Yes
103TXNRD1659044617245-1.098-0.5531Yes
104UBE2D24590671 651044617253-1.102-0.5449Yes
105MAPK14529073117315-1.150-0.5393Yes
106SUPV3L1117007217329-1.165-0.5309Yes
107SIRT1119073117371-1.201-0.5238Yes
108HSPH1169001717447-1.265-0.5180Yes
109RBM1787059217448-1.265-0.5082Yes
110GTF2B686068517511-1.328-0.5012Yes
111TMPO405049417673-1.489-0.4984Yes
112XBP1384059417677-1.491-0.4870Yes
113TOP2A36071717707-1.531-0.4766Yes
114ELOVL6534074617800-1.633-0.4689Yes
115OSBPL9257037317888-1.715-0.4603Yes
116MCTS1613013317980-1.821-0.4511Yes
117TNFSF5IP1206009518012-1.858-0.4383Yes
118RAP1B371013818017-1.861-0.4240Yes
119POLD3640027818063-1.899-0.4117Yes
120UBE2D3319045218074-1.915-0.3974Yes
121MAP3K7604006818082-1.929-0.3828Yes
122PCNA94075418090-1.941-0.3681Yes
123PJA243053718146-2.037-0.3552Yes
124GTF2H2513035818171-2.069-0.3404Yes
125DDX21610044618174-2.073-0.3244Yes
126FNTA7005918207-2.120-0.3097Yes
127HDAC2405043318244-2.188-0.2946Yes
128SLC25A17210036918246-2.189-0.2777Yes
129TBK1569033818268-2.222-0.2615Yes
130PRKACB421017018277-2.235-0.2446Yes
131RIPK1319002518291-2.264-0.2277Yes
132CCNH319034718307-2.289-0.2107Yes
133RPP14704001418382-2.470-0.1955Yes
134PSMA4456042718418-2.539-0.1777Yes
135DDX20329034818454-2.649-0.1590Yes
136RABGGTB312003718464-2.678-0.1387Yes
137RAB1A237067118476-2.727-0.1181Yes
138PSMD14569059318497-2.806-0.0974Yes
139OGT2360131 461033318507-2.829-0.0759Yes
140CCT4638016118545-3.052-0.0541Yes
141LBR454067118590-3.582-0.0287Yes
142SLC4A1AP319057618602-3.8660.0008Yes
Table: GSEA details [plain text format]



Fig 2: ET743_SARCOMA_48HRS_DN   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: ET743_SARCOMA_48HRS_DN: Random ES distribution   
Gene set null distribution of ES for ET743_SARCOMA_48HRS_DN