Dataset | Set_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls #truncNotch_versus_wtNotch |
Phenotype | phenotype_truncNotch_versus_wtNotch.cls#truncNotch_versus_wtNotch |
Upregulated in class | wtNotch |
GeneSet | REACTOME_CELL_CYCLE__MITOTIC |
Enrichment Score (ES) | -0.5601966 |
Normalized Enrichment Score (NES) | -1.7248632 |
Nominal p-value | 0.0 |
FDR q-value | 0.1358082 |
FWER p-Value | 0.371 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | TYMS | 940450 1940068 3710008 5570546 | 288 | 2.473 | 0.0055 | No | ||
2 | CDK4 | 540075 4540600 | 515 | 2.120 | 0.0114 | No | ||
3 | TK2 | 70725 | 531 | 2.101 | 0.0285 | No | ||
4 | PSMD2 | 4670706 5050364 | 941 | 1.679 | 0.0207 | No | ||
5 | CDC25B | 6940102 | 1097 | 1.538 | 0.0255 | No | ||
6 | PSMA1 | 380059 2760195 | 1149 | 1.500 | 0.0355 | No | ||
7 | PSMC1 | 6350538 | 1283 | 1.414 | 0.0404 | No | ||
8 | CCNE1 | 110064 | 1324 | 1.384 | 0.0500 | No | ||
9 | PSMD9 | 50020 5890368 | 1407 | 1.336 | 0.0570 | No | ||
10 | PMF1 | 5130273 | 1425 | 1.325 | 0.0674 | No | ||
11 | RFC5 | 3800452 6020091 | 1531 | 1.251 | 0.0724 | No | ||
12 | POLD1 | 4830026 | 1795 | 1.079 | 0.0674 | No | ||
13 | RANGAP1 | 2320593 6650601 | 1814 | 1.071 | 0.0755 | No | ||
14 | PSMA7 | 2230131 | 2006 | 0.993 | 0.0737 | No | ||
15 | TUBB4 | 5310681 | 2432 | 0.789 | 0.0574 | No | ||
16 | LIG1 | 1980438 4540112 5570609 | 2526 | 0.754 | 0.0588 | No | ||
17 | PRKACA | 2640731 4050048 | 2625 | 0.708 | 0.0595 | No | ||
18 | PSMB10 | 630504 6510039 | 2884 | 0.604 | 0.0507 | No | ||
19 | NUMA1 | 6520576 | 3038 | 0.548 | 0.0471 | No | ||
20 | TUBA4A | 6900279 | 3097 | 0.530 | 0.0485 | No | ||
21 | E2F1 | 5360093 | 3237 | 0.483 | 0.0451 | No | ||
22 | POLD2 | 6400148 | 3283 | 0.469 | 0.0467 | No | ||
23 | MCM2 | 5050139 | 3319 | 0.459 | 0.0487 | No | ||
24 | BUB3 | 3170546 | 3396 | 0.440 | 0.0483 | No | ||
25 | CDC20 | 3440017 3440044 6220088 | 3513 | 0.413 | 0.0456 | No | ||
26 | MCM5 | 2680647 | 3531 | 0.411 | 0.0482 | No | ||
27 | DCTN2 | 540471 3780717 | 3928 | 0.333 | 0.0296 | No | ||
28 | SSNA1 | 360593 | 4019 | 0.317 | 0.0274 | No | ||
29 | ACTR1A | 5860070 | 4070 | 0.308 | 0.0273 | No | ||
30 | PSMA5 | 5390537 | 4404 | 0.258 | 0.0115 | No | ||
31 | PLK4 | 430162 5720110 | 4615 | 0.232 | 0.0021 | No | ||
32 | TUBA1A | 610128 4540347 6420070 6980181 | 4716 | 0.220 | -0.0014 | No | ||
33 | POLA2 | 940519 | 4916 | 0.200 | -0.0105 | No | ||
34 | KIF20A | 2650050 | 5090 | 0.183 | -0.0183 | No | ||
35 | UBE2C | 6130017 | 5204 | 0.173 | -0.0229 | No | ||
36 | MCM3 | 5570068 | 5213 | 0.172 | -0.0219 | No | ||
37 | PLK1 | 1780369 2640121 | 5389 | 0.159 | -0.0300 | No | ||
38 | PSMB4 | 520402 | 5847 | 0.127 | -0.0536 | No | ||
39 | CENPE | 2850022 | 5869 | 0.126 | -0.0537 | No | ||
40 | CLIP1 | 2850162 6770397 | 6789 | 0.084 | -0.1027 | No | ||
41 | NUP37 | 2370097 6370435 6380008 | 6973 | 0.077 | -0.1120 | No | ||
42 | RFC3 | 1980600 | 7145 | 0.072 | -0.1206 | No | ||
43 | PSMB9 | 6980471 | 7156 | 0.072 | -0.1205 | No | ||
44 | PAFAH1B1 | 4230333 6420121 6450066 | 7219 | 0.070 | -0.1233 | No | ||
45 | NEK2 | 2120520 | 7723 | 0.056 | -0.1500 | No | ||
46 | CDK7 | 2640451 | 7739 | 0.056 | -0.1504 | No | ||
47 | PSMA3 | 5900047 7040161 | 8176 | 0.045 | -0.1736 | No | ||
48 | PSMC3 | 2480184 | 8367 | 0.041 | -0.1835 | No | ||
49 | SGOL1 | 1980075 5220092 6020711 | 8402 | 0.040 | -0.1850 | No | ||
50 | PSMD5 | 3940139 4570041 | 8769 | 0.033 | -0.2046 | No | ||
51 | KIF2A | 3990286 6130575 | 8816 | 0.032 | -0.2068 | No | ||
52 | POLE2 | 6110041 | 9434 | 0.021 | -0.2400 | No | ||
53 | POLA1 | 4760541 | 9609 | 0.018 | -0.2493 | No | ||
54 | DYNLL1 | 5570113 | 9946 | 0.013 | -0.2673 | No | ||
55 | BUB1 | 5390270 | 10159 | 0.009 | -0.2787 | No | ||
56 | PSMA6 | 50609 | 10307 | 0.006 | -0.2866 | No | ||
57 | CCNA1 | 6290113 | 10793 | -0.001 | -0.3129 | No | ||
58 | XPO1 | 540707 | 10863 | -0.002 | -0.3166 | No | ||
59 | PSMD8 | 630142 | 11013 | -0.005 | -0.3246 | No | ||
60 | UBE2D1 | 1850400 | 11164 | -0.007 | -0.3327 | No | ||
61 | CLASP2 | 2510139 | 11412 | -0.011 | -0.3460 | No | ||
62 | CENPC1 | 610273 | 11790 | -0.018 | -0.3662 | No | ||
63 | CDKN1A | 4050088 6400706 | 11801 | -0.019 | -0.3666 | No | ||
64 | SDCCAG8 | 1780687 | 12332 | -0.030 | -0.3950 | No | ||
65 | CCNB2 | 6510528 | 13046 | -0.050 | -0.4332 | No | ||
66 | PSMB5 | 6290242 | 13050 | -0.050 | -0.4329 | No | ||
67 | MCM10 | 4920632 | 13362 | -0.062 | -0.4492 | No | ||
68 | DHFR | 6350315 | 13517 | -0.069 | -0.4570 | No | ||
69 | PSMD11 | 2340538 6510053 | 13588 | -0.072 | -0.4602 | No | ||
70 | DCTN3 | 6840131 | 13849 | -0.085 | -0.4735 | No | ||
71 | PTTG1 | 520463 | 13883 | -0.086 | -0.4745 | No | ||
72 | OFD1 | 4810670 | 14367 | -0.123 | -0.4996 | No | ||
73 | CDC25C | 2570673 4760161 6520707 | 14375 | -0.124 | -0.4990 | No | ||
74 | ORC2L | 1990470 6510019 | 14587 | -0.144 | -0.5092 | No | ||
75 | WEE1 | 3390070 | 14732 | -0.160 | -0.5156 | No | ||
76 | YWHAE | 5310435 | 14848 | -0.178 | -0.5203 | No | ||
77 | CLASP1 | 6860279 | 15087 | -0.218 | -0.5313 | No | ||
78 | ORC1L | 2370328 6110390 | 15143 | -0.230 | -0.5323 | No | ||
79 | PPP1CC | 6380300 2510647 | 15240 | -0.251 | -0.5354 | No | ||
80 | TUBG1 | 3140204 | 15374 | -0.280 | -0.5402 | No | ||
81 | RPA2 | 2760301 5420195 | 15395 | -0.283 | -0.5389 | No | ||
82 | CDK2 | 130484 2260301 4010088 5050110 | 15400 | -0.284 | -0.5367 | No | ||
83 | FEN1 | 1770541 | 15480 | -0.302 | -0.5383 | No | ||
84 | PSMB2 | 940035 4210324 | 15519 | -0.313 | -0.5377 | No | ||
85 | PSMB1 | 2940402 | 15530 | -0.317 | -0.5356 | No | ||
86 | RANBP2 | 4280338 | 15909 | -0.437 | -0.5523 | No | ||
87 | STAG2 | 4540132 | 16056 | -0.485 | -0.5561 | Yes | ||
88 | ORC4L | 4230538 5550288 | 16081 | -0.494 | -0.5531 | Yes | ||
89 | PRKAR2B | 3130593 5220577 | 16104 | -0.501 | -0.5501 | Yes | ||
90 | PSME3 | 2810537 | 16141 | -0.515 | -0.5476 | Yes | ||
91 | PSMC4 | 580050 1580025 | 16153 | -0.518 | -0.5438 | Yes | ||
92 | SEC13 | 380577 | 16229 | -0.549 | -0.5432 | Yes | ||
93 | PSMC6 | 2810021 | 16260 | -0.560 | -0.5400 | Yes | ||
94 | MCM7 | 3290292 5220056 | 16282 | -0.569 | -0.5363 | Yes | ||
95 | CDC25A | 3800184 | 16404 | -0.617 | -0.5376 | Yes | ||
96 | CCNA2 | 5290075 | 16440 | -0.634 | -0.5340 | Yes | ||
97 | PSMC5 | 2760315 6550021 | 16473 | -0.650 | -0.5302 | Yes | ||
98 | CSNK1E | 2850347 5050093 6110301 | 16546 | -0.684 | -0.5283 | Yes | ||
99 | CDC45L | 70537 3130114 | 16566 | -0.690 | -0.5234 | Yes | ||
100 | BIRC5 | 110408 580014 1770632 | 16722 | -0.790 | -0.5251 | Yes | ||
101 | CENPA | 5080154 | 16744 | -0.803 | -0.5194 | Yes | ||
102 | PSMD3 | 1400647 | 16762 | -0.811 | -0.5134 | Yes | ||
103 | NUP43 | 3360482 | 16806 | -0.839 | -0.5085 | Yes | ||
104 | RAD21 | 1990278 | 16835 | -0.856 | -0.5027 | Yes | ||
105 | GMNN | 2630148 | 16925 | -0.916 | -0.4997 | Yes | ||
106 | KNTC1 | 430079 | 16964 | -0.940 | -0.4937 | Yes | ||
107 | CDC16 | 1940706 | 17027 | -0.980 | -0.4887 | Yes | ||
108 | PRIM1 | 6420746 | 17077 | -0.999 | -0.4829 | Yes | ||
109 | CETN2 | 3170148 | 17139 | -1.024 | -0.4774 | Yes | ||
110 | ZW10 | 2900735 3520687 | 17254 | -1.103 | -0.4742 | Yes | ||
111 | SMC1A | 3060600 5700148 5890113 6370154 | 17283 | -1.130 | -0.4660 | Yes | ||
112 | UBE2E1 | 4230064 1090440 | 17347 | -1.186 | -0.4593 | Yes | ||
113 | PSMD4 | 430068 | 17380 | -1.214 | -0.4507 | Yes | ||
114 | KIF23 | 5570112 | 17597 | -1.409 | -0.4503 | Yes | ||
115 | ORC5L | 1940133 1940711 | 17603 | -1.414 | -0.4385 | Yes | ||
116 | NUP160 | 1990551 | 17608 | -1.419 | -0.4266 | Yes | ||
117 | ZWINT | 6940670 | 17662 | -1.481 | -0.4169 | Yes | ||
118 | MCM4 | 2760673 5420711 | 17712 | -1.538 | -0.4064 | Yes | ||
119 | YWHAG | 3780341 | 17748 | -1.581 | -0.3948 | Yes | ||
120 | NDC80 | 4120465 | 17749 | -1.583 | -0.3813 | Yes | ||
121 | MNAT1 | 730292 2350364 | 17785 | -1.616 | -0.3694 | Yes | ||
122 | RPA3 | 5700136 | 17795 | -1.631 | -0.3559 | Yes | ||
123 | CUL1 | 1990632 | 17844 | -1.677 | -0.3442 | Yes | ||
124 | SGOL2 | 2030338 | 17861 | -1.693 | -0.3306 | Yes | ||
125 | RFC1 | 1190673 | 17986 | -1.828 | -0.3217 | Yes | ||
126 | MAPRE1 | 3290037 | 17996 | -1.839 | -0.3065 | Yes | ||
127 | POLD3 | 6400278 | 18063 | -1.899 | -0.2939 | Yes | ||
128 | PCNA | 940754 | 18090 | -1.941 | -0.2787 | Yes | ||
129 | PSMD12 | 730044 | 18128 | -2.007 | -0.2636 | Yes | ||
130 | FGFR1OP | 6510300 | 18156 | -2.046 | -0.2476 | Yes | ||
131 | RB1 | 5900338 | 18226 | -2.152 | -0.2329 | Yes | ||
132 | RPA1 | 360452 | 18231 | -2.159 | -0.2147 | Yes | ||
133 | PSMA2 | 6510093 | 18263 | -2.215 | -0.1975 | Yes | ||
134 | CCNH | 3190347 | 18307 | -2.289 | -0.1802 | Yes | ||
135 | PSMD7 | 2030619 6220594 | 18323 | -2.337 | -0.1611 | Yes | ||
136 | MAD2L1 | 4480725 | 18343 | -2.379 | -0.1418 | Yes | ||
137 | POLE | 6020538 | 18351 | -2.398 | -0.1217 | Yes | ||
138 | BUB1B | 1450288 | 18355 | -2.413 | -0.1013 | Yes | ||
139 | CCNB1 | 4590433 4780372 | 18405 | -2.518 | -0.0824 | Yes | ||
140 | PSMA4 | 4560427 | 18418 | -2.539 | -0.0614 | Yes | ||
141 | NUP107 | 6380021 | 18420 | -2.542 | -0.0398 | Yes | ||
142 | PSMD14 | 5690593 | 18497 | -2.806 | -0.0199 | Yes | ||
143 | RFC4 | 3800082 6840142 | 18552 | -3.081 | 0.0035 | Yes |