Details for gene set UVC_XPCS_8HR

Table: GSEA Results Summary

Dataset	Set_03_absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls #truncNotch_versus_absentNotch
Phenotype	phenotype_absentNotch_versus_truncNotch.cls#truncNotch_versus_absentNotch
Upregulated in class	absentNotch
GeneSet	UVC_XPCS_8HR_DN
Enrichment Score (ES)	-0.6068977
Normalized Enrichment Score (NES)	-1.9084365
Nominal p-value	0.0
FDR q-value	0.0038725424
FWER p-Value	0.0030

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	IGF2BP3	2810161 4230338	544	2.645	-0.0180	No
2	ARHGEF10	3120593 6900673	1012	2.008	-0.0346	No
3	SLC25A12	7400731	1050	1.964	-0.0279	No
4	LHFPL2	450020	1124	1.894	-0.0235	No
5	SMAD3	6450671	1267	1.764	-0.0235	No
6	MYST3	5270500	1396	1.648	-0.0232	No
7	ATXN2	3940017 4810242	1662	1.473	-0.0311	No
8	ZMYND11	630181 2570019 4850138 5360040	1725	1.433	-0.0282	No
9	XPO6	3940019	1827	1.328	-0.0278	No
10	SON	3120148 5860239 7040403	1865	1.303	-0.0240	No
11	USP24	870672 4560100	2048	1.172	-0.0288	No
12	RBM16	6290286 6400181	2068	1.162	-0.0247	No
13	NUP98	2850465	2161	1.097	-0.0249	No
14	PCMT1	4590338 4590541	2306	1.019	-0.0282	No
15	PRKCA	6400551	2627	0.839	-0.0420	No
16	CRIM1	130491	2907	0.690	-0.0541	No
17	SEPT9	1940040	3014	0.643	-0.0571	No
18	DLG1	2630091 6020286	3119	0.602	-0.0601	No
19	CLOCK	1410070 2940292 3390075	3181	0.581	-0.0608	No
20	PKN2	940746 2350168	3193	0.577	-0.0589	No
21	ZHX3	460615	3194	0.576	-0.0563	No
22	NFKB1	5420358	3229	0.564	-0.0557	No
23	CDS2	1570520	3267	0.549	-0.0553	No
24	CDK8	1050113 1190601 1780358 6110102	3281	0.544	-0.0536	No
25	DOCK9	5080037	3334	0.527	-0.0541	No
26	DLC1	1090632 6450594	3366	0.516	-0.0535	No
27	TJP2	3870397 5570324	3477	0.477	-0.0574	No
28	SSBP2	2260725 2900400 4730711	3630	0.435	-0.0638	No
29	ANKS1A	50148	3710	0.415	-0.0663	No
30	CDYL	4200142 4730397 6060400	3724	0.411	-0.0651	No
31	CBLB	3520465 4670348	3829	0.390	-0.0691	No
32	MGLL	2030446 4210520	3832	0.389	-0.0675	No
33	IL7R	2060088 6380500	3854	0.383	-0.0669	No
34	GTF2F2	2690546	3876	0.378	-0.0664	No
35	INPP5F	60010 5360164	3879	0.377	-0.0649	No
36	EGFR	4920138 6480521	4005	0.351	-0.0701	No
37	SOCS5	3830398 7100093	4072	0.339	-0.0722	No
38	MKLN1	70504 1850129	4081	0.338	-0.0712	No
39	MICAL3	6040333	4106	0.333	-0.0710	No
40	ATP2C1	2630446 6520253	4121	0.331	-0.0703	No
41	FGF2	3450433	4167	0.323	-0.0713	No
42	HOXB2	6450592	4220	0.314	-0.0728	No
43	EXT1	4540603	4264	0.307	-0.0738	No
44	XRCC4	1690685 6660427	4267	0.306	-0.0725	No
45	RB1CC1	510494 7100072	4312	0.298	-0.0736	No
46	CDH2	520435 2450451 2760025 6650477	4395	0.285	-0.0768	No
47	SERPINE1	4210403	4396	0.285	-0.0756	No
48	CUL2	4200278	4463	0.274	-0.0779	No
49	RRAS2	6290170	4474	0.272	-0.0773	No
50	GRK5	1940348 4670053	4533	0.262	-0.0793	No
51	MDN1	60671 770091	4594	0.254	-0.0814	No
52	HIVEP1	3850632	4659	0.246	-0.0838	No
53	PPP2R5C	3310121 6650672	4724	0.238	-0.0863	No
54	PBX3	1300424 3710577 6180575	4738	0.236	-0.0859	No
55	DOCK4	5910102	4811	0.229	-0.0889	No
56	PAFAH1B1	4230333 6420121 6450066	4946	0.213	-0.0952	No
57	ABCE1	4280050	4988	0.209	-0.0965	No
58	ZZZ3	780133 2320239 2640452 5080706 6550341	5399	0.167	-0.1182	No
59	PMM2	670673 2570044 2690093 4540068 6450056	5442	0.164	-0.1197	No
60	CD2AP	1940369	5498	0.159	-0.1220	No
61	IL1RAP	50546 450711 1580397 3940301 5890181 6370373	5500	0.159	-0.1214	No
62	TUBGCP3	4920563	5692	0.145	-0.1312	No
63	DNMBP	2810368 6900403	5859	0.134	-0.1396	No
64	USP9X	130435 2370735 3120338	5935	0.128	-0.1432	No
65	CXCL12	580546 4150750 4570068	5956	0.127	-0.1437	No
66	ATRX	2340039 3610132 4210373	6109	0.118	-0.1515	No
67	PKP4	3710400 5890097	6121	0.117	-0.1515	No
68	EPHA4	460750	6198	0.113	-0.1552	No
69	PARN	3840129	6332	0.106	-0.1620	No
70	BCAR3	1660717	6388	0.102	-0.1645	No
71	PHF21A	610014	6463	0.099	-0.1681	No
72	TRAM2	3940112	6497	0.098	-0.1695	No
73	NBN	730538 2470619 4780594	6543	0.095	-0.1715	No
74	CREB3L2	3390484	6599	0.093	-0.1741	No
75	WASF3	5130017	6649	0.091	-0.1764	No
76	FARS2	5340575	6664	0.091	-0.1768	No
77	MID1	4070114 4760458	6716	0.089	-0.1791	No
78	DDX10	520746	6767	0.086	-0.1815	No
79	RAGE	730102 2120706 7050315	6846	0.083	-0.1854	No
80	PHLPP	3440563	6987	0.078	-0.1927	No
81	KIAA0427	1690435	7074	0.075	-0.1970	No
82	PRKCI	5420139	7178	0.072	-0.2023	No
83	GNAQ	430670 4210131 5900736	7189	0.072	-0.2026	No
84	NPEPPS	2630731	7313	0.068	-0.2090	No
85	CNOT2	520546 2060397 4610543 5550113	7406	0.064	-0.2137	No
86	LRPPRC	2370072 2470408	7464	0.063	-0.2165	No
87	MTX2	6660288	7523	0.061	-0.2194	No
88	TDRD7	6550520	7895	0.053	-0.2394	No
89	CENPE	2850022	8038	0.049	-0.2470	No
90	CRADD	6770520	8067	0.049	-0.2483	No
91	RNF13	2370021	8379	0.042	-0.2651	No
92	MYO1B	770372	8443	0.041	-0.2683	No
93	TRIM2	430546 1170286	8514	0.039	-0.2720	No
94	NRG1	1050332	8525	0.039	-0.2723	No
95	PTPN2	130315	8559	0.038	-0.2740	No
96	SRGAP2	1050092 1230403 3830066 6130215	8902	0.031	-0.2925	No
97	NMT2	6900148	9143	0.026	-0.3055	No
98	RGS7	3390044	9319	0.023	-0.3149	No
99	ITSN1	2640577	9376	0.022	-0.3179	No
100	NFYC	1400746	9433	0.021	-0.3209	No
101	GBE1	2190368	9606	0.018	-0.3302	No
102	FBXW11	6450632	9778	0.015	-0.3394	No
103	LYN	6040600	9800	0.015	-0.3405	No
104	PTX3	870309 3520102	9822	0.014	-0.3416	No
105	EPS8	7050204	9837	0.014	-0.3423	No
106	SATB2	2470181	9856	0.014	-0.3432	No
107	RPGR	5910711	10210	0.008	-0.3624	No
108	SAMD4A	1170717	10258	0.007	-0.3650	No
109	NEK7	4540026	10604	0.001	-0.3838	No
110	NR2F2	3170609 3310577	10615	0.001	-0.3843	No
111	SLIT2	1940037	10629	0.001	-0.3850	No
112	HOMER1	360131 1690092 1990300 4590068	10640	0.000	-0.3856	No
113	STAG1	1190300 1400722 4590100	10654	0.000	-0.3863	No
114	KIF11	5390139	10668	0.000	-0.3870	No
115	EPS15	4200215	10846	-0.003	-0.3966	No
116	PUM2	4200441 5910446	10923	-0.004	-0.4008	No
117	PLEKHC1	2650066	10996	-0.005	-0.4047	No
118	XPO1	540707	11124	-0.008	-0.4116	No
119	ARHGEF7	1690441	11219	-0.009	-0.4167	No
120	PLCB4	50576	11247	-0.010	-0.4181	No
121	ADAM10	3780156	11270	-0.010	-0.4193	No
122	TLE4	1450064 1500519	11293	-0.010	-0.4204	No
123	AUH	5570152	11416	-0.013	-0.4270	No
124	E2F5	5860575	11453	-0.014	-0.4289	No
125	GLRB	2510433 4280736	11617	-0.017	-0.4377	No
126	CLASP2	2510139	11667	-0.018	-0.4403	No
127	VEGFC	5910494	11694	-0.018	-0.4417	No
128	USP13	1450670	11797	-0.020	-0.4471	No
129	RAB6A	3840463 4780731	11950	-0.023	-0.4553	No
130	EHBP1	430348	11986	-0.024	-0.4571	No
131	PLCE1	4780685	12013	-0.025	-0.4584	No
132	CENPF	5050088	12052	-0.026	-0.4604	No
133	TIPARP	50397	12055	-0.026	-0.4604	No
134	SCHIP1	4560152	12061	-0.026	-0.4606	No
135	TRIM37	5270091	12097	-0.026	-0.4623	No
136	DPYD	6110095	12303	-0.031	-0.4734	No
137	TGFB2	4920292	12423	-0.034	-0.4797	No
138	FGF5	5270204	12662	-0.041	-0.4925	No
139	TSPAN5	6770019	12666	-0.041	-0.4925	No
140	PKD2	4670390	12709	-0.042	-0.4946	No
141	GOLGA4	460300	12800	-0.045	-0.4993	No
142	OSBPL8	50603	12866	-0.047	-0.5027	No
143	PARD3	3390324 5390541	12872	-0.047	-0.5028	No
144	ZCCHC11	3390731 5360039	12890	-0.048	-0.5035	No
145	IGF1R	3360494	12897	-0.048	-0.5036	No
146	CDC42BPA	840671	12955	-0.050	-0.5065	No
147	F3	2940180	13140	-0.056	-0.5163	No
148	MYST4	1400563 2570687 3360458 6840402	13280	-0.061	-0.5236	No
149	LARS2	7000706	13363	-0.065	-0.5278	No
150	RAD23B	2190671	13382	-0.065	-0.5285	No
151	SEC14L1	2120551 3610537	13384	-0.065	-0.5282	No
152	PIK3C2A	6040593	13385	-0.065	-0.5279	No
153	SEMA3C	7000020	13391	-0.066	-0.5279	No
154	IRAK1BP1	610037	13405	-0.066	-0.5283	No
155	ACSL3	3140195	13515	-0.072	-0.5340	No
156	STK24	6760484	13657	-0.079	-0.5413	No
157	PTPN12	2030309 6020725 6130746 6290609	13765	-0.085	-0.5468	No
158	FYN	2100468 4760520 4850687	13831	-0.091	-0.5499	No
159	KLF6	110541 5360026	13853	-0.092	-0.5507	No
160	DAPK1	5570010	13872	-0.093	-0.5512	No
161	TOPBP1	6020333	14021	-0.105	-0.5588	No
162	PTPRK	1450433 2640142	14037	-0.106	-0.5592	No
163	NUP133	2360168 4760017	14251	-0.127	-0.5703	No
164	STARD13	540722	14252	-0.128	-0.5697	No
165	SLC7A1	2450193 2710241	14336	-0.137	-0.5736	No
166	MYO10	3830576 5570092	14462	-0.153	-0.5798	No
167	ATRN	870735 3360390	14468	-0.154	-0.5793	No
168	NUMB	2450735 3800253 6350040	14665	-0.187	-0.5892	No
169	STK39	50692	14763	-0.207	-0.5936	No
170	ORC2L	1990470 6510019	14885	-0.231	-0.5992	No
171	RGS20	4540541 4730086	14926	-0.242	-0.6003	No
172	RANBP2	4280338	14930	-0.242	-0.5994	No
173	TCF7L2	2190348 5220113	14949	-0.248	-0.5993	No
174	ZFYVE9	6980288 7100017	14979	-0.254	-0.5997	No
175	FNDC3A	2690097 3290044	14981	-0.255	-0.5986	No
176	BARD1	3170348	15004	-0.261	-0.5987	No
177	EIF4E	1580403 70133 6380215	15012	-0.264	-0.5979	No
178	CASK	2340215 3290576 6770215	15035	-0.271	-0.5979	No
179	LASS6	5890576 6520138	15109	-0.294	-0.6006	No
180	ROCK2	1780035 5720025	15118	-0.295	-0.5997	No
181	R3HDM1	940685 3290161	15131	-0.299	-0.5991	No
182	KIF5C	6370717	15143	-0.304	-0.5983	No
183	STK3	7100427	15154	-0.306	-0.5975	No
184	USP12	6130735 6620280	15158	-0.309	-0.5963	No
185	PICALM	1940280	15162	-0.310	-0.5951	No
186	MALT1	4670292	15166	-0.311	-0.5939	No
187	MYC	380541 4670170	15244	-0.337	-0.5966	No
188	NRIP1	3190039	15347	-0.369	-0.6005	No
189	PAWR	5130546 6330706	15356	-0.372	-0.5993	No
190	ATF2	2260348 2480441	15390	-0.383	-0.5994	No
191	PDE8A	5080446	15528	-0.429	-0.6050	Yes
192	MELK	130022 5220537	15534	-0.430	-0.6034	Yes
193	NEDD4	460736 1190280	15556	-0.438	-0.6026	Yes
194	CTBP2	430309 3710079	15569	-0.445	-0.6013	Yes
195	ARFGEF1	6760494	15585	-0.452	-0.6001	Yes
196	ATP11B	4230100	15594	-0.454	-0.5985	Yes
197	STRN3	1450093 6200685	15595	-0.454	-0.5965	Yes
198	ZNF148	6420403	15604	-0.459	-0.5949	Yes
199	FUT8	1340068 2340056	15634	-0.470	-0.5944	Yes
200	MSH2	6180273	15689	-0.488	-0.5952	Yes
201	MYO9B	1230435 3060358	15742	-0.510	-0.5958	Yes
202	IFRD1	4590215	15760	-0.519	-0.5944	Yes
203	THRAP2	4920600	15773	-0.524	-0.5928	Yes
204	MPHOSPH1	4610427	15799	-0.532	-0.5918	Yes
205	ANKRD17	2120402 3850035 6400044	15875	-0.565	-0.5934	Yes
206	PPM1B	380180 450154 3610215	15964	-0.611	-0.5955	Yes
207	ADARB1	780451	15984	-0.617	-0.5938	Yes
208	SMURF2	1940161	15992	-0.622	-0.5914	Yes
209	SOS2	2060722	16027	-0.639	-0.5904	Yes
210	ADCY9	5690168	16077	-0.656	-0.5902	Yes
211	TRIM33	580619 2230280 3990433 6200747	16084	-0.659	-0.5876	Yes
212	GMPS	460670	16093	-0.663	-0.5851	Yes
213	MAP2K1	840739	16129	-0.683	-0.5840	Yes
214	PPP1R12A	4070066 4590162	16223	-0.748	-0.5858	Yes
215	RNGTT	780152 780746 1090471	16226	-0.749	-0.5826	Yes
216	DYRK1A	3190181	16263	-0.763	-0.5812	Yes
217	WDR7	670279 1090121	16267	-0.765	-0.5779	Yes
218	PEX3	2760100	16274	-0.769	-0.5749	Yes
219	PCCA	3390400	16284	-0.773	-0.5719	Yes
220	NCOA3	4540195	16332	-0.802	-0.5710	Yes
221	KPNA3	7040088	16389	-0.834	-0.5703	Yes
222	PTEN	3390064	16399	-0.838	-0.5671	Yes
223	CLASP1	6860279	16434	-0.859	-0.5652	Yes
224	RPS6KA3	1980707	16486	-0.889	-0.5640	Yes
225	OPA1	2030433 3520390 4730537	16561	-0.937	-0.5639	Yes
226	SLC25A13	4920072 5690722	16566	-0.939	-0.5600	Yes
227	ANKMY2	780600 2230440	16699	-1.001	-0.5627	Yes
228	SEC24B	460717 3060040	16731	-1.021	-0.5599	Yes
229	NVL	2690687 6900735	16781	-1.057	-0.5579	Yes
230	REV3L	1090717	16793	-1.065	-0.5538	Yes
231	PRIM2A	7000692	16825	-1.081	-0.5507	Yes
232	PCNT	4760053	16856	-1.102	-0.5475	Yes
233	STAU2	2810411	16870	-1.117	-0.5433	Yes
234	ITSN2	780484	16896	-1.139	-0.5396	Yes
235	THBS2	2850136	16899	-1.140	-0.5346	Yes
236	MARK3	2370450	16905	-1.145	-0.5298	Yes
237	NT5C2	4280735 4670528	16909	-1.148	-0.5249	Yes
238	RYK	1500338 1770072	16976	-1.208	-0.5232	Yes
239	MBNL1	2640762 7100048	17040	-1.263	-0.5210	Yes
240	PJA2	430537	17072	-1.296	-0.5170	Yes
241	OGT	2360131 4610333	17074	-1.298	-0.5113	Yes
242	DNAJC13	4730091	17096	-1.317	-0.5066	Yes
243	ZNF638	6510112	17142	-1.369	-0.5030	Yes
244	ATR	6860273	17157	-1.381	-0.4977	Yes
245	TIAM1	5420288	17196	-1.424	-0.4935	Yes
246	SMC5	3440164	17324	-1.561	-0.4935	Yes
247	TCF12	3610324 7000156	17340	-1.578	-0.4873	Yes
248	CUL1	1990632	17375	-1.620	-0.4820	Yes
249	CENTG2	4210053	17380	-1.626	-0.4751	Yes
250	CHD1	4590048	17440	-1.692	-0.4708	Yes
251	ARIH1	6900025	17448	-1.698	-0.4637	Yes
252	TOP2A	360717	17451	-1.703	-0.4562	Yes
253	TRIP12	130154 5080288 5720446	17466	-1.728	-0.4493	Yes
254	IBTK	780242	17497	-1.759	-0.4432	Yes
255	TLE1	540390 1580309 3710019	17508	-1.770	-0.4359	Yes
256	RUNX1	3840711	17573	-1.837	-0.4313	Yes
257	UPF2	4810471	17631	-1.906	-0.4260	Yes
258	MAN2A1	6650176	17674	-1.980	-0.4195	Yes
259	TLK2	1170161	17708	-2.029	-0.4123	Yes
260	RAD51C	3780592	17714	-2.044	-0.4036	Yes
261	RASA1	1240315	17822	-2.176	-0.3998	Yes
262	PPP2R5E	70671 2120056	17840	-2.202	-0.3910	Yes
263	UBE2D2	4590671 6510446	17855	-2.229	-0.3819	Yes
264	ORC5L	1940133 1940711	17862	-2.234	-0.3723	Yes
265	SFRS3	770315 4230593	17869	-2.240	-0.3627	Yes
266	TBL1X	6400524	17890	-2.280	-0.3537	Yes
267	RAB6IP1	4150044	17915	-2.320	-0.3448	Yes
268	UBL3	6450458	17992	-2.441	-0.3381	Yes
269	HNRPDL	1050102 1090181 5360471	18013	-2.480	-0.3283	Yes
270	PAIP1	3870576	18053	-2.557	-0.3191	Yes
271	CREBBP	5690035 7040050	18081	-2.625	-0.3089	Yes
272	GSK3B	5360348	18106	-2.696	-0.2983	Yes
273	CUTL1	1570113 1770091 1850273 2100286 5340605	18147	-2.771	-0.2883	Yes
274	PARG	50139	18158	-2.797	-0.2764	Yes
275	SLC4A7	2370056	18169	-2.822	-0.2645	Yes
276	RB1	5900338	18205	-2.912	-0.2535	Yes
277	PIK3C3	6590717	18230	-2.975	-0.2417	Yes
278	FCHSD2	5720092	18323	-3.256	-0.2323	Yes
279	MTAP	2120136	18339	-3.321	-0.2184	Yes
280	KLF7	50390	18427	-3.660	-0.2070	Yes
281	EIF4G3	670707	18431	-3.687	-0.1908	Yes
282	TLK1	7100605	18433	-3.696	-0.1745	Yes
283	MAP2K4	5130133	18441	-3.735	-0.1584	Yes
284	SRPK2	6380341	18529	-4.282	-0.1442	Yes
285	UBE2G1	2230546 5420528 7040463	18536	-4.350	-0.1253	Yes
286	DHX15	870632	18572	-4.807	-0.1059	Yes
287	PRMT3	1660609	18601	-5.671	-0.0824	Yes
288	APPBP2	5130215	18603	-5.776	-0.0569	Yes
289	PRKACB	4210170	18607	-6.062	-0.0302	Yes
290	PTK2	1780148	18615	-6.937	0.0001	Yes