Details for gene set UVC_TTD_ALL

Table: GSEA Results Summary

Dataset	Set_03_absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls #truncNotch_versus_absentNotch
Phenotype	phenotype_absentNotch_versus_truncNotch.cls#truncNotch_versus_absentNotch
Upregulated in class	absentNotch
GeneSet	UVC_TTD_ALL_DN
Enrichment Score (ES)	-0.5996542
Normalized Enrichment Score (NES)	-1.867711
Nominal p-value	0.0
FDR q-value	0.0038856366
FWER p-Value	0.018

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	IGF2BP3	2810161 4230338	544	2.645	-0.0163	No
2	PEX14	520603	1024	1.999	-0.0323	No
3	LHFPL2	450020	1124	1.894	-0.0282	No
4	SMAD3	6450671	1267	1.764	-0.0270	No
5	MYST3	5270500	1396	1.648	-0.0257	No
6	MTMR3	1050014 4920180	1625	1.493	-0.0305	No
7	ATXN2	3940017 4810242	1662	1.473	-0.0251	No
8	ZMYND11	630181 2570019 4850138 5360040	1725	1.433	-0.0212	No
9	RBM16	6290286 6400181	2068	1.162	-0.0340	No
10	NUP98	2850465	2161	1.097	-0.0335	No
11	CTAGE5	70053 2100435 6020692	2303	1.019	-0.0360	No
12	PRKCA	6400551	2627	0.839	-0.0494	No
13	PPP2R2A	2900014 5700575	2726	0.786	-0.0508	No
14	HAS2	5360181	2891	0.694	-0.0562	No
15	SEPT9	1940040	3014	0.643	-0.0596	No
16	HIRA	4480609 5270167	3125	0.601	-0.0626	No
17	PKN2	940746 2350168	3193	0.577	-0.0633	No
18	ZHX3	460615	3194	0.576	-0.0604	No
19	ZHX2	2900452	3220	0.567	-0.0589	No
20	CDK8	1050113 1190601 1780358 6110102	3281	0.544	-0.0594	No
21	DLC1	1090632 6450594	3366	0.516	-0.0614	No
22	RBM6	840279 3840563 4780129 6020446	3373	0.514	-0.0591	No
23	MGAT5	1770592 6940441	3378	0.513	-0.0568	No
24	SWAP70	2810577 2850739 5130594	3516	0.466	-0.0619	No
25	DAAM1	1500273	3599	0.442	-0.0641	No
26	MTF2	50333	3610	0.438	-0.0625	No
27	SSBP2	2260725 2900400 4730711	3630	0.435	-0.0613	No
28	CCND1	460524 770309 3120576 6980398	3689	0.419	-0.0624	No
29	ANKS1A	50148	3710	0.415	-0.0613	No
30	CDYL	4200142 4730397 6060400	3724	0.411	-0.0600	No
31	CBLB	3520465 4670348	3829	0.390	-0.0637	No
32	MGLL	2030446 4210520	3832	0.389	-0.0618	No
33	IL7R	2060088 6380500	3854	0.383	-0.0610	No
34	GTF2F2	2690546	3876	0.378	-0.0603	No
35	INPP5F	60010 5360164	3879	0.377	-0.0585	No
36	EGFR	4920138 6480521	4005	0.351	-0.0635	No
37	SOCS5	3830398 7100093	4072	0.339	-0.0654	No
38	PPAP2B	3190397 4730280	4078	0.339	-0.0640	No
39	FGF2	3450433	4167	0.323	-0.0671	No
40	EXT1	4540603	4264	0.307	-0.0708	No
41	XRCC4	1690685 6660427	4267	0.306	-0.0694	No
42	SERPINE1	4210403	4396	0.285	-0.0749	No
43	RRAS2	6290170	4474	0.272	-0.0777	No
44	MDN1	60671 770091	4594	0.254	-0.0829	No
45	PBX3	1300424 3710577 6180575	4738	0.236	-0.0895	No
46	SLIT1	50110	4769	0.233	-0.0900	No
47	GPR176	130017	4846	0.226	-0.0930	No
48	CENPA	5080154	4878	0.221	-0.0936	No
49	PAFAH1B1	4230333 6420121 6450066	4946	0.213	-0.0962	No
50	CREB5	2320368	5120	0.191	-0.1046	No
51	ZZZ3	780133 2320239 2640452 5080706 6550341	5399	0.167	-0.1189	No
52	BMP2K	60541 5570504	5451	0.163	-0.1209	No
53	CD2AP	1940369	5498	0.159	-0.1226	No
54	IL1RAP	50546 450711 1580397 3940301 5890181 6370373	5500	0.159	-0.1218	No
55	GULP1	2230725 2350039 5570446	5540	0.156	-0.1232	No
56	ARID5B	110403	5631	0.150	-0.1273	No
57	TUBGCP3	4920563	5692	0.145	-0.1298	No
58	DNMBP	2810368 6900403	5859	0.134	-0.1382	No
59	CXCL12	580546 4150750 4570068	5956	0.127	-0.1428	No
60	FTO	1690477	6087	0.119	-0.1493	No
61	KIF2A	3990286 6130575	6089	0.119	-0.1487	No
62	ATRX	2340039 3610132 4210373	6109	0.118	-0.1492	No
63	PKP4	3710400 5890097	6121	0.117	-0.1492	No
64	EPHA4	460750	6198	0.113	-0.1528	No
65	CAP2	7100315	6254	0.110	-0.1552	No
66	ATXN1	5550156	6268	0.109	-0.1554	No
67	BCAR3	1660717	6388	0.102	-0.1613	No
68	TRAM2	3940112	6497	0.098	-0.1667	No
69	SOS1	7050338	6527	0.096	-0.1678	No
70	FARS2	5340575	6664	0.091	-0.1748	No
71	NFIB	460450	6690	0.089	-0.1757	No
72	GALK2	2360632	6713	0.089	-0.1764	No
73	MID1	4070114 4760458	6716	0.089	-0.1761	No
74	DDX10	520746	6767	0.086	-0.1784	No
75	RGL1	1500097 6900450	6958	0.079	-0.1883	No
76	PHLPP	3440563	6987	0.078	-0.1895	No
77	PTPRM	6370136	7093	0.075	-0.1948	No
78	ANAPC10	870086 1170037 2260129	7177	0.072	-0.1990	No
79	GNAQ	430670 4210131 5900736	7189	0.072	-0.1992	No
80	CNOT2	520546 2060397 4610543 5550113	7406	0.064	-0.2106	No
81	FBXL7	6620711	7955	0.051	-0.2402	No
82	CENPE	2850022	8038	0.049	-0.2445	No
83	CRADD	6770520	8067	0.049	-0.2457	No
84	SYNJ2	3170524	8231	0.045	-0.2544	No
85	ACVR2A	6110647	8377	0.042	-0.2621	No
86	RNF13	2370021	8379	0.042	-0.2619	No
87	MYO1B	770372	8443	0.041	-0.2652	No
88	ROR1	6220026	8461	0.040	-0.2659	No
89	NRG1	1050332	8525	0.039	-0.2691	No
90	RABGAP1L	3190014 6860088	8556	0.038	-0.2706	No
91	PTPN2	130315	8559	0.038	-0.2705	No
92	SKAP2	6760500	8593	0.037	-0.2721	No
93	WDFY3	3610041 4560333 4570273	8747	0.034	-0.2802	No
94	TRIM24	7050670	8765	0.034	-0.2810	No
95	SRGAP2	1050092 1230403 3830066 6130215	8902	0.031	-0.2883	No
96	SMAD7	430377	9300	0.023	-0.3098	No
97	RGS7	3390044	9319	0.023	-0.3106	No
98	ITSN1	2640577	9376	0.022	-0.3136	No
99	CTGF	4540577	9479	0.020	-0.3190	No
100	GBE1	2190368	9606	0.018	-0.3258	No
101	FBXW11	6450632	9778	0.015	-0.3350	No
102	LYN	6040600	9800	0.015	-0.3361	No
103	SATB2	2470181	9856	0.014	-0.3390	No
104	ERC1	1580170 2630717 6110762 6840280	9933	0.012	-0.3431	No
105	SAMD4A	1170717	10258	0.007	-0.3607	No
106	NUP153	7000452	10430	0.004	-0.3700	No
107	ARNT2	1740594	10535	0.002	-0.3757	No
108	NEK7	4540026	10604	0.001	-0.3794	No
109	SHB	4920494	10628	0.001	-0.3806	No
110	HOMER1	360131 1690092 1990300 4590068	10640	0.000	-0.3812	No
111	STAG1	1190300 1400722 4590100	10654	0.000	-0.3819	No
112	KLF10	4850056	10681	-0.000	-0.3834	No
113	PCTK2	5700673	10825	-0.002	-0.3911	No
114	PUM2	4200441 5910446	10923	-0.004	-0.3964	No
115	PLEKHC1	2650066	10996	-0.005	-0.4003	No
116	CRY1	6770039	11048	-0.006	-0.4030	No
117	ARHGEF7	1690441	11219	-0.009	-0.4123	No
118	TLE4	1450064 1500519	11293	-0.010	-0.4162	No
119	AUH	5570152	11416	-0.013	-0.4228	No
120	CLASP2	2510139	11667	-0.018	-0.4363	No
121	VEGFC	5910494	11694	-0.018	-0.4376	No
122	EHBP1	430348	11986	-0.024	-0.4534	No
123	SCHIP1	4560152	12061	-0.026	-0.4573	No
124	MITF	380056	12093	-0.026	-0.4588	No
125	SLC16A7	2320672	12147	-0.028	-0.4616	No
126	DPYD	6110095	12303	-0.031	-0.4699	No
127	TGFB2	4920292	12423	-0.034	-0.4762	No
128	ARHGAP12	1050181	12556	-0.038	-0.4832	No
129	EDG2	6290215	12557	-0.038	-0.4830	No
130	FGF5	5270204	12662	-0.041	-0.4884	No
131	TSPAN5	6770019	12666	-0.041	-0.4884	No
132	GOLGA4	460300	12800	-0.045	-0.4954	No
133	PARD3	3390324 5390541	12872	-0.047	-0.4990	No
134	ZCCHC11	3390731 5360039	12890	-0.048	-0.4997	No
135	CDC42BPA	840671	12955	-0.050	-0.5030	No
136	BICD1	110128 2940324	13048	-0.053	-0.5077	No
137	COL5A2	780040	13100	-0.054	-0.5102	No
138	F3	2940180	13140	-0.056	-0.5121	No
139	MYST4	1400563 2570687 3360458 6840402	13280	-0.061	-0.5193	No
140	LARS2	7000706	13363	-0.065	-0.5235	No
141	GNAI1	4560390	13389	-0.065	-0.5245	No
142	SEMA3C	7000020	13391	-0.066	-0.5242	No
143	IRAK1BP1	610037	13405	-0.066	-0.5246	No
144	BLM	520619 5570170	13581	-0.075	-0.5338	No
145	PTPN12	2030309 6020725 6130746 6290609	13765	-0.085	-0.5433	No
146	FYN	2100468 4760520 4850687	13831	-0.091	-0.5464	No
147	SERPINB2	70487	13867	-0.093	-0.5478	No
148	DAPK1	5570010	13872	-0.093	-0.5476	No
149	JMJD2C	3290341	13956	-0.099	-0.5516	No
150	TOPBP1	6020333	14021	-0.105	-0.5545	No
151	PTPRK	1450433 2640142	14037	-0.106	-0.5548	No
152	ACVR1	6840671	14141	-0.115	-0.5599	No
153	UST	2100053	14174	-0.119	-0.5610	No
154	STARD13	540722	14252	-0.128	-0.5645	No
155	THRAP1	2470121	14284	-0.131	-0.5656	No
156	PIP5K3	5360112	14309	-0.134	-0.5662	No
157	DUSP1	6860121	14399	-0.144	-0.5703	No
158	MYO10	3830576 5570092	14462	-0.153	-0.5729	No
159	SPAG9	580497 2510180 4210685	14493	-0.157	-0.5738	No
160	STK39	50692	14763	-0.207	-0.5874	No
161	ORC2L	1990470 6510019	14885	-0.231	-0.5928	No
162	RGS20	4540541 4730086	14926	-0.242	-0.5938	No
163	TCF7L2	2190348 5220113	14949	-0.248	-0.5937	No
164	ZFYVE9	6980288 7100017	14979	-0.254	-0.5940	No
165	FNDC3A	2690097 3290044	14981	-0.255	-0.5928	No
166	DOK5	770113 3450156	15003	-0.261	-0.5926	No
167	BARD1	3170348	15004	-0.261	-0.5913	No
168	EIF4E	1580403 70133 6380215	15012	-0.264	-0.5904	No
169	CASK	2340215 3290576 6770215	15035	-0.271	-0.5902	No
170	LASS6	5890576 6520138	15109	-0.294	-0.5927	No
171	ROCK2	1780035 5720025	15118	-0.295	-0.5916	No
172	ZRF1	6020181 6510484	15127	-0.297	-0.5906	No
173	STK3	7100427	15154	-0.306	-0.5904	No
174	MYC	380541 4670170	15244	-0.337	-0.5936	No
175	E2F3	50162 460180	15296	-0.350	-0.5946	No
176	NRIP1	3190039	15347	-0.369	-0.5955	No
177	MAD1L1	5700035	15378	-0.379	-0.5952	No
178	ATF2	2260348 2480441	15390	-0.383	-0.5939	No
179	MARCH7	3800020 6620168	15392	-0.383	-0.5920	No
180	MELK	130022 5220537	15534	-0.430	-0.5975	Yes
181	CTBP2	430309 3710079	15569	-0.445	-0.5971	Yes
182	ARFGEF1	6760494	15585	-0.452	-0.5956	Yes
183	STRN3	1450093 6200685	15595	-0.454	-0.5938	Yes
184	ZNF148	6420403	15604	-0.459	-0.5920	Yes
185	FUT8	1340068 2340056	15634	-0.470	-0.5912	Yes
186	AMPH	2260338 3140576	15669	-0.480	-0.5906	Yes
187	AQR	3800139	15696	-0.492	-0.5895	Yes
188	MAST2	6200348	15711	-0.496	-0.5878	Yes
189	FLNB	2510575	15755	-0.516	-0.5875	Yes
190	IFRD1	4590215	15760	-0.519	-0.5851	Yes
191	THRAP2	4920600	15773	-0.524	-0.5831	Yes
192	MPHOSPH1	4610427	15799	-0.532	-0.5818	Yes
193	ANKRD17	2120402 3850035 6400044	15875	-0.565	-0.5831	Yes
194	MAP4K5	3190286 4760300 5270070 5550494	15930	-0.591	-0.5830	Yes
195	MSH3	6770575	15968	-0.612	-0.5819	Yes
196	SMURF2	1940161	15992	-0.622	-0.5801	Yes
197	TRIM33	580619 2230280 3990433 6200747	16084	-0.659	-0.5817	Yes
198	LRP6	5130064	16112	-0.674	-0.5798	Yes
199	SLC25A24	5360017 5860484	16117	-0.676	-0.5766	Yes
200	TDRD3	540292	16172	-0.710	-0.5759	Yes
201	CNOT4	2320242 6760706	16176	-0.713	-0.5725	Yes
202	PPP1R12A	4070066 4590162	16223	-0.748	-0.5712	Yes
203	RNGTT	780152 780746 1090471	16226	-0.749	-0.5676	Yes
204	LRIG1	1050136	16231	-0.750	-0.5640	Yes
205	DYRK1A	3190181	16263	-0.763	-0.5619	Yes
206	WDR7	670279 1090121	16267	-0.765	-0.5582	Yes
207	NCOA3	4540195	16332	-0.802	-0.5576	Yes
208	CLASP1	6860279	16434	-0.859	-0.5588	Yes
209	BHLHB2	7040603	16464	-0.878	-0.5559	Yes
210	CASP8	4850154	16519	-0.907	-0.5543	Yes
211	SOCS6	1170347 7100280	16564	-0.938	-0.5520	Yes
212	SLC25A13	4920072 5690722	16566	-0.939	-0.5473	Yes
213	ATBF1	1240131 7040465	16717	-1.013	-0.5503	Yes
214	SEC24B	460717 3060040	16731	-1.021	-0.5459	Yes
215	REV3L	1090717	16793	-1.065	-0.5438	Yes
216	EVI5	6380040	16807	-1.070	-0.5392	Yes
217	PRIM2A	7000692	16825	-1.081	-0.5346	Yes
218	ITSN2	780484	16896	-1.139	-0.5327	Yes
219	MBNL1	2640762 7100048	17040	-1.263	-0.5341	Yes
220	OGT	2360131 4610333	17074	-1.298	-0.5294	Yes
221	ZNF638	6510112	17142	-1.369	-0.5261	Yes
222	WDHD1	3450390	17327	-1.563	-0.5283	Yes
223	TCF12	3610324 7000156	17340	-1.578	-0.5210	Yes
224	CENTG2	4210053	17380	-1.626	-0.5149	Yes
225	CHD1	4590048	17440	-1.692	-0.5096	Yes
226	ARIH1	6900025	17448	-1.698	-0.5014	Yes
227	MPP6	6020148	17471	-1.734	-0.4938	Yes
228	TLE1	540390 1580309 3710019	17508	-1.770	-0.4869	Yes
229	ENC1	4810348	17562	-1.828	-0.4805	Yes
230	RUNX1	3840711	17573	-1.837	-0.4718	Yes
231	UPF2	4810471	17631	-1.906	-0.4653	Yes
232	TLK2	1170161	17708	-2.029	-0.4592	Yes
233	PPP2R5E	70671 2120056	17840	-2.202	-0.4553	Yes
234	UGCG	3420053	17861	-2.234	-0.4451	Yes
235	ORC5L	1940133 1940711	17862	-2.234	-0.4338	Yes
236	ZNF292	840736 1500390	17882	-2.263	-0.4234	Yes
237	TBL1X	6400524	17890	-2.280	-0.4123	Yes
238	SIPA1L1	50292	17907	-2.305	-0.4016	Yes
239	RBM39	4230458 6450280	17941	-2.355	-0.3915	Yes
240	KIF23	5570112	17948	-2.363	-0.3799	Yes
241	NCOA1	3610438	17979	-2.418	-0.3693	Yes
242	UBL3	6450458	17992	-2.441	-0.3577	Yes
243	HNRPDL	1050102 1090181 5360471	18013	-2.480	-0.3463	Yes
244	CREBBP	5690035 7040050	18081	-2.625	-0.3367	Yes
245	GSK3B	5360348	18106	-2.696	-0.3244	Yes
246	CUTL1	1570113 1770091 1850273 2100286 5340605	18147	-2.771	-0.3126	Yes
247	PARG	50139	18158	-2.797	-0.2990	Yes
248	SLC4A7	2370056	18169	-2.822	-0.2853	Yes
249	FCHSD2	5720092	18323	-3.256	-0.2772	Yes
250	MNAT1	730292 2350364	18373	-3.445	-0.2625	Yes
251	KLF7	50390	18427	-3.660	-0.2470	Yes
252	EIF4G3	670707	18431	-3.687	-0.2285	Yes
253	TLK1	7100605	18433	-3.696	-0.2100	Yes
254	MAP2K4	5130133	18441	-3.735	-0.1915	Yes
255	ABI1	2850152	18454	-3.784	-0.1731	Yes
256	SRPK2	6380341	18529	-4.282	-0.1555	Yes
257	FUBP1	5390373	18545	-4.465	-0.1338	Yes
258	SPOP	450035	18556	-4.589	-0.1112	Yes
259	DHX15	870632	18572	-4.807	-0.0878	Yes
260	MAPK6	6760520	18578	-4.847	-0.0636	Yes
261	PRKACB	4210170	18607	-6.062	-0.0346	Yes
262	PTK2	1780148	18615	-6.937	0.0001	Yes