Details for gene set UVC_TTD_4HR

Table: GSEA Results Summary

Dataset	Set_03_absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls #truncNotch_versus_absentNotch
Phenotype	phenotype_absentNotch_versus_truncNotch.cls#truncNotch_versus_absentNotch
Upregulated in class	absentNotch
GeneSet	UVC_TTD_4HR_DN
Enrichment Score (ES)	-0.61383533
Normalized Enrichment Score (NES)	-1.9049189
Nominal p-value	0.0
FDR q-value	0.0026046238
FWER p-Value	0.0040

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	IGF2BP3	2810161 4230338	544	2.645	-0.0147	No
2	PEX14	520603	1024	1.999	-0.0295	No
3	LHFPL2	450020	1124	1.894	-0.0243	No
4	SMAD3	6450671	1267	1.764	-0.0221	No
5	MYST3	5270500	1396	1.648	-0.0198	No
6	MTMR3	1050014 4920180	1625	1.493	-0.0238	No
7	ATXN2	3940017 4810242	1662	1.473	-0.0175	No
8	RBM16	6290286 6400181	2068	1.162	-0.0330	No
9	NUP98	2850465	2161	1.097	-0.0319	No
10	CTAGE5	70053 2100435 6020692	2303	1.019	-0.0338	No
11	PRKCA	6400551	2627	0.839	-0.0466	No
12	PPP2R2A	2900014 5700575	2726	0.786	-0.0476	No
13	HAS2	5360181	2891	0.694	-0.0526	No
14	HIRA	4480609 5270167	3125	0.601	-0.0619	No
15	PKN2	940746 2350168	3193	0.577	-0.0623	No
16	ZHX3	460615	3194	0.576	-0.0590	No
17	ZHX2	2900452	3220	0.567	-0.0572	No
18	CDK8	1050113 1190601 1780358 6110102	3281	0.544	-0.0574	No
19	DLC1	1090632 6450594	3366	0.516	-0.0591	No
20	RBM6	840279 3840563 4780129 6020446	3373	0.514	-0.0565	No
21	MGAT5	1770592 6940441	3378	0.513	-0.0539	No
22	SWAP70	2810577 2850739 5130594	3516	0.466	-0.0587	No
23	DAAM1	1500273	3599	0.442	-0.0607	No
24	MTF2	50333	3610	0.438	-0.0588	No
25	SSBP2	2260725 2900400 4730711	3630	0.435	-0.0574	No
26	ANKS1A	50148	3710	0.415	-0.0593	No
27	CDYL	4200142 4730397 6060400	3724	0.411	-0.0577	No
28	CBLB	3520465 4670348	3829	0.390	-0.0612	No
29	IL7R	2060088 6380500	3854	0.383	-0.0603	No
30	INPP5F	60010 5360164	3879	0.377	-0.0595	No
31	EGFR	4920138 6480521	4005	0.351	-0.0644	No
32	SOCS5	3830398 7100093	4072	0.339	-0.0660	No
33	PPAP2B	3190397 4730280	4078	0.339	-0.0644	No
34	FGF2	3450433	4167	0.323	-0.0674	No
35	EXT1	4540603	4264	0.307	-0.0709	No
36	XRCC4	1690685 6660427	4267	0.306	-0.0693	No
37	RRAS2	6290170	4474	0.272	-0.0789	No
38	MDN1	60671 770091	4594	0.254	-0.0840	No
39	PBX3	1300424 3710577 6180575	4738	0.236	-0.0904	No
40	SLIT1	50110	4769	0.233	-0.0907	No
41	CENPA	5080154	4878	0.221	-0.0954	No
42	PAFAH1B1	4230333 6420121 6450066	4946	0.213	-0.0978	No
43	CREB5	2320368	5120	0.191	-0.1061	No
44	ZZZ3	780133 2320239 2640452 5080706 6550341	5399	0.167	-0.1203	No
45	BMP2K	60541 5570504	5451	0.163	-0.1222	No
46	CD2AP	1940369	5498	0.159	-0.1238	No
47	IL1RAP	50546 450711 1580397 3940301 5890181 6370373	5500	0.159	-0.1229	No
48	GULP1	2230725 2350039 5570446	5540	0.156	-0.1242	No
49	ARID5B	110403	5631	0.150	-0.1282	No
50	TUBGCP3	4920563	5692	0.145	-0.1307	No
51	DNMBP	2810368 6900403	5859	0.134	-0.1389	No
52	KIF2A	3990286 6130575	6089	0.119	-0.1507	No
53	EPHA4	460750	6198	0.113	-0.1560	No
54	ATXN1	5550156	6268	0.109	-0.1591	No
55	BCAR3	1660717	6388	0.102	-0.1650	No
56	TRAM2	3940112	6497	0.098	-0.1703	No
57	SOS1	7050338	6527	0.096	-0.1713	No
58	MID1	4070114 4760458	6716	0.089	-0.1811	No
59	DDX10	520746	6767	0.086	-0.1833	No
60	RGL1	1500097 6900450	6958	0.079	-0.1932	No
61	PHLPP	3440563	6987	0.078	-0.1943	No
62	ANAPC10	870086 1170037 2260129	7177	0.072	-0.2041	No
63	GNAQ	430670 4210131 5900736	7189	0.072	-0.2043	No
64	CNOT2	520546 2060397 4610543 5550113	7406	0.064	-0.2157	No
65	FBXL7	6620711	7955	0.051	-0.2452	No
66	CENPE	2850022	8038	0.049	-0.2494	No
67	SYNJ2	3170524	8231	0.045	-0.2595	No
68	ACVR2A	6110647	8377	0.042	-0.2672	No
69	RNF13	2370021	8379	0.042	-0.2670	No
70	ROR1	6220026	8461	0.040	-0.2712	No
71	PTPN2	130315	8559	0.038	-0.2762	No
72	WDFY3	3610041 4560333 4570273	8747	0.034	-0.2862	No
73	TRIM24	7050670	8765	0.034	-0.2870	No
74	SRGAP2	1050092 1230403 3830066 6130215	8902	0.031	-0.2942	No
75	RGS7	3390044	9319	0.023	-0.3166	No
76	ITSN1	2640577	9376	0.022	-0.3196	No
77	CTGF	4540577	9479	0.020	-0.3250	No
78	FBXW11	6450632	9778	0.015	-0.3411	No
79	LYN	6040600	9800	0.015	-0.3422	No
80	SAMD4A	1170717	10258	0.007	-0.3670	No
81	NUP153	7000452	10430	0.004	-0.3762	No
82	ARNT2	1740594	10535	0.002	-0.3819	No
83	NEK7	4540026	10604	0.001	-0.3856	No
84	HOMER1	360131 1690092 1990300 4590068	10640	0.000	-0.3875	No
85	STAG1	1190300 1400722 4590100	10654	0.000	-0.3882	No
86	KLF10	4850056	10681	-0.000	-0.3896	No
87	PCTK2	5700673	10825	-0.002	-0.3973	No
88	PUM2	4200441 5910446	10923	-0.004	-0.4026	No
89	PLEKHC1	2650066	10996	-0.005	-0.4065	No
90	CRY1	6770039	11048	-0.006	-0.4092	No
91	ARHGEF7	1690441	11219	-0.009	-0.4184	No
92	TLE4	1450064 1500519	11293	-0.010	-0.4223	No
93	AUH	5570152	11416	-0.013	-0.4289	No
94	CLASP2	2510139	11667	-0.018	-0.4423	No
95	VEGFC	5910494	11694	-0.018	-0.4437	No
96	EHBP1	430348	11986	-0.024	-0.4593	No
97	SCHIP1	4560152	12061	-0.026	-0.4632	No
98	MITF	380056	12093	-0.026	-0.4647	No
99	SLC16A7	2320672	12147	-0.028	-0.4675	No
100	TGFB2	4920292	12423	-0.034	-0.4822	No
101	ARHGAP12	1050181	12556	-0.038	-0.4892	No
102	EDG2	6290215	12557	-0.038	-0.4890	No
103	FGF5	5270204	12662	-0.041	-0.4944	No
104	TSPAN5	6770019	12666	-0.041	-0.4943	No
105	GOLGA4	460300	12800	-0.045	-0.5013	No
106	PARD3	3390324 5390541	12872	-0.047	-0.5049	No
107	ZCCHC11	3390731 5360039	12890	-0.048	-0.5056	No
108	BICD1	110128 2940324	13048	-0.053	-0.5138	No
109	F3	2940180	13140	-0.056	-0.5184	No
110	MYST4	1400563 2570687 3360458 6840402	13280	-0.061	-0.5256	No
111	LARS2	7000706	13363	-0.065	-0.5297	No
112	GNAI1	4560390	13389	-0.065	-0.5307	No
113	SEMA3C	7000020	13391	-0.066	-0.5304	No
114	IRAK1BP1	610037	13405	-0.066	-0.5307	No
115	BLM	520619 5570170	13581	-0.075	-0.5398	No
116	PTPN12	2030309 6020725 6130746 6290609	13765	-0.085	-0.5493	No
117	FYN	2100468 4760520 4850687	13831	-0.091	-0.5523	No
118	DAPK1	5570010	13872	-0.093	-0.5540	No
119	JMJD2C	3290341	13956	-0.099	-0.5579	No
120	TOPBP1	6020333	14021	-0.105	-0.5608	No
121	PTPRK	1450433 2640142	14037	-0.106	-0.5610	No
122	ACVR1	6840671	14141	-0.115	-0.5660	No
123	UST	2100053	14174	-0.119	-0.5671	No
124	STARD13	540722	14252	-0.128	-0.5705	No
125	THRAP1	2470121	14284	-0.131	-0.5715	No
126	PIP5K3	5360112	14309	-0.134	-0.5720	No
127	MYO10	3830576 5570092	14462	-0.153	-0.5794	No
128	STK39	50692	14763	-0.207	-0.5946	No
129	ORC2L	1990470 6510019	14885	-0.231	-0.5999	No
130	TCF7L2	2190348 5220113	14949	-0.248	-0.6019	No
131	ZFYVE9	6980288 7100017	14979	-0.254	-0.6020	No
132	FNDC3A	2690097 3290044	14981	-0.255	-0.6007	No
133	BARD1	3170348	15004	-0.261	-0.6004	No
134	EIF4E	1580403 70133 6380215	15012	-0.264	-0.5993	No
135	ROCK2	1780035 5720025	15118	-0.295	-0.6033	No
136	ZRF1	6020181 6510484	15127	-0.297	-0.6021	No
137	STK3	7100427	15154	-0.306	-0.6018	No
138	E2F3	50162 460180	15296	-0.350	-0.6075	No
139	NRIP1	3190039	15347	-0.369	-0.6081	No
140	ATF2	2260348 2480441	15390	-0.383	-0.6083	No
141	MARCH7	3800020 6620168	15392	-0.383	-0.6062	No
142	MELK	130022 5220537	15534	-0.430	-0.6114	Yes
143	CTBP2	430309 3710079	15569	-0.445	-0.6108	Yes
144	ARFGEF1	6760494	15585	-0.452	-0.6091	Yes
145	STRN3	1450093 6200685	15595	-0.454	-0.6070	Yes
146	ZNF148	6420403	15604	-0.459	-0.6049	Yes
147	AQR	3800139	15696	-0.492	-0.6070	Yes
148	IFRD1	4590215	15760	-0.519	-0.6075	Yes
149	THRAP2	4920600	15773	-0.524	-0.6053	Yes
150	MPHOSPH1	4610427	15799	-0.532	-0.6036	Yes
151	ANKRD17	2120402 3850035 6400044	15875	-0.565	-0.6045	Yes
152	MAP4K5	3190286 4760300 5270070 5550494	15930	-0.591	-0.6042	Yes
153	MSH3	6770575	15968	-0.612	-0.6027	Yes
154	SMURF2	1940161	15992	-0.622	-0.6005	Yes
155	TRIM33	580619 2230280 3990433 6200747	16084	-0.659	-0.6017	Yes
156	LRP6	5130064	16112	-0.674	-0.5994	Yes
157	SLC25A24	5360017 5860484	16117	-0.676	-0.5959	Yes
158	CNOT4	2320242 6760706	16176	-0.713	-0.5950	Yes
159	PPP1R12A	4070066 4590162	16223	-0.748	-0.5933	Yes
160	RNGTT	780152 780746 1090471	16226	-0.749	-0.5892	Yes
161	LRIG1	1050136	16231	-0.750	-0.5852	Yes
162	DYRK1A	3190181	16263	-0.763	-0.5826	Yes
163	WDR7	670279 1090121	16267	-0.765	-0.5785	Yes
164	NCOA3	4540195	16332	-0.802	-0.5775	Yes
165	CLASP1	6860279	16434	-0.859	-0.5781	Yes
166	BHLHB2	7040603	16464	-0.878	-0.5748	Yes
167	CASP8	4850154	16519	-0.907	-0.5726	Yes
168	SOCS6	1170347 7100280	16564	-0.938	-0.5698	Yes
169	ATBF1	1240131 7040465	16717	-1.013	-0.5723	Yes
170	SEC24B	460717 3060040	16731	-1.021	-0.5673	Yes
171	REV3L	1090717	16793	-1.065	-0.5647	Yes
172	EVI5	6380040	16807	-1.070	-0.5594	Yes
173	PRIM2A	7000692	16825	-1.081	-0.5542	Yes
174	ITSN2	780484	16896	-1.139	-0.5516	Yes
175	OGT	2360131 4610333	17074	-1.298	-0.5540	Yes
176	ZNF638	6510112	17142	-1.369	-0.5499	Yes
177	WDHD1	3450390	17327	-1.563	-0.5512	Yes
178	TCF12	3610324 7000156	17340	-1.578	-0.5430	Yes
179	CENTG2	4210053	17380	-1.626	-0.5360	Yes
180	CHD1	4590048	17440	-1.692	-0.5297	Yes
181	ARIH1	6900025	17448	-1.698	-0.5205	Yes
182	MPP6	6020148	17471	-1.734	-0.5120	Yes
183	TLE1	540390 1580309 3710019	17508	-1.770	-0.5040	Yes
184	RUNX1	3840711	17573	-1.837	-0.4972	Yes
185	UPF2	4810471	17631	-1.906	-0.4896	Yes
186	TLK2	1170161	17708	-2.029	-0.4823	Yes
187	PPP2R5E	70671 2120056	17840	-2.202	-0.4771	Yes
188	UGCG	3420053	17861	-2.234	-0.4656	Yes
189	ORC5L	1940133 1940711	17862	-2.234	-0.4531	Yes
190	ZNF292	840736 1500390	17882	-2.263	-0.4414	Yes
191	TBL1X	6400524	17890	-2.280	-0.4290	Yes
192	SIPA1L1	50292	17907	-2.305	-0.4170	Yes
193	RBM39	4230458 6450280	17941	-2.355	-0.4055	Yes
194	KIF23	5570112	17948	-2.363	-0.3926	Yes
195	NCOA1	3610438	17979	-2.418	-0.3807	Yes
196	UBL3	6450458	17992	-2.441	-0.3676	Yes
197	HNRPDL	1050102 1090181 5360471	18013	-2.480	-0.3548	Yes
198	CREBBP	5690035 7040050	18081	-2.625	-0.3437	Yes
199	GSK3B	5360348	18106	-2.696	-0.3299	Yes
200	CUTL1	1570113 1770091 1850273 2100286 5340605	18147	-2.771	-0.3165	Yes
201	PARG	50139	18158	-2.797	-0.3014	Yes
202	SLC4A7	2370056	18169	-2.822	-0.2861	Yes
203	FCHSD2	5720092	18323	-3.256	-0.2761	Yes
204	MNAT1	730292 2350364	18373	-3.445	-0.2595	Yes
205	KLF7	50390	18427	-3.660	-0.2418	Yes
206	EIF4G3	670707	18431	-3.687	-0.2213	Yes
207	TLK1	7100605	18433	-3.696	-0.2006	Yes
208	MAP2K4	5130133	18441	-3.735	-0.1800	Yes
209	ABI1	2850152	18454	-3.784	-0.1594	Yes
210	SRPK2	6380341	18529	-4.282	-0.1394	Yes
211	FUBP1	5390373	18545	-4.465	-0.1152	Yes
212	SPOP	450035	18556	-4.589	-0.0900	Yes
213	DHX15	870632	18572	-4.807	-0.0638	Yes
214	MAPK6	6760520	18578	-4.847	-0.0369	Yes
215	PTK2	1780148	18615	-6.937	0.0001	Yes