Dataset | Set_03_absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls #truncNotch_versus_absentNotch |
Phenotype | phenotype_absentNotch_versus_truncNotch.cls#truncNotch_versus_absentNotch |
Upregulated in class | absentNotch |
GeneSet | UVC_HIGH_ALL_DN |
Enrichment Score (ES) | -0.596776 |
Normalized Enrichment Score (NES) | -1.8490193 |
Nominal p-value | 0.0 |
FDR q-value | 0.0055914633 |
FWER p-Value | 0.03 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | LSM2 | 510082 | 302 | 3.185 | -0.0018 | No | ||
2 | PHC2 | 1430433 | 327 | 3.113 | 0.0112 | No | ||
3 | IGF2BP3 | 2810161 4230338 | 544 | 2.645 | 0.0115 | No | ||
4 | PARP1 | 4780446 6400338 | 804 | 2.259 | 0.0078 | No | ||
5 | PTPN1 | 2650056 | 874 | 2.174 | 0.0141 | No | ||
6 | UNG | 3130110 6100364 | 931 | 2.088 | 0.0206 | No | ||
7 | GNE | 6100465 | 1110 | 1.908 | 0.0197 | No | ||
8 | LHFPL2 | 450020 | 1124 | 1.894 | 0.0276 | No | ||
9 | SMAD3 | 6450671 | 1267 | 1.764 | 0.0280 | No | ||
10 | USP10 | 2030736 2450333 | 1399 | 1.644 | 0.0284 | No | ||
11 | MTMR3 | 1050014 4920180 | 1625 | 1.493 | 0.0230 | No | ||
12 | TRIP10 | 460438 | 1838 | 1.322 | 0.0176 | No | ||
13 | ARF6 | 3520026 | 1902 | 1.273 | 0.0200 | No | ||
14 | FZD2 | 6480154 | 2084 | 1.150 | 0.0154 | No | ||
15 | TARDBP | 870390 2350093 | 2211 | 1.070 | 0.0135 | No | ||
16 | TWIST1 | 5130619 | 2330 | 1.005 | 0.0117 | No | ||
17 | IFNGR2 | 1500288 2100176 | 2606 | 0.850 | 0.0006 | No | ||
18 | SRF | 70139 2320039 | 2690 | 0.804 | -0.0002 | No | ||
19 | PMP22 | 4010239 6550072 | 2853 | 0.715 | -0.0057 | No | ||
20 | HAS2 | 5360181 | 2891 | 0.694 | -0.0045 | No | ||
21 | SIAH2 | 7210672 | 2948 | 0.672 | -0.0045 | No | ||
22 | FBXO46 | 870273 | 2974 | 0.662 | -0.0028 | No | ||
23 | NAP1L1 | 2510593 5900215 5090470 450079 4920280 | 3038 | 0.634 | -0.0033 | No | ||
24 | ZHX3 | 460615 | 3194 | 0.576 | -0.0091 | No | ||
25 | ELF4 | 4850193 | 3259 | 0.552 | -0.0101 | No | ||
26 | CDK8 | 1050113 1190601 1780358 6110102 | 3281 | 0.544 | -0.0087 | No | ||
27 | UBE2N | 520369 2900047 | 3333 | 0.527 | -0.0091 | No | ||
28 | PLK4 | 430162 5720110 | 3404 | 0.506 | -0.0106 | No | ||
29 | HERPUD1 | 7100440 | 3496 | 0.470 | -0.0134 | No | ||
30 | SWAP70 | 2810577 2850739 5130594 | 3516 | 0.466 | -0.0123 | No | ||
31 | CDYL | 4200142 4730397 6060400 | 3724 | 0.411 | -0.0216 | No | ||
32 | FADD | 2360593 4210692 6520019 | 3820 | 0.392 | -0.0250 | No | ||
33 | TRIB2 | 4120605 | 3902 | 0.373 | -0.0277 | No | ||
34 | UBTF | 4210450 6840403 | 4028 | 0.347 | -0.0329 | No | ||
35 | PPAP2B | 3190397 4730280 | 4078 | 0.339 | -0.0340 | No | ||
36 | HOXB2 | 6450592 | 4220 | 0.314 | -0.0402 | No | ||
37 | USP1 | 2760541 5690438 6220673 | 4294 | 0.302 | -0.0428 | No | ||
38 | HDHD1A | 6220328 | 4386 | 0.286 | -0.0464 | No | ||
39 | NFIL3 | 4070377 | 4428 | 0.278 | -0.0474 | No | ||
40 | RRAS2 | 6290170 | 4474 | 0.272 | -0.0486 | No | ||
41 | CEBPD | 3360176 | 4567 | 0.258 | -0.0524 | No | ||
42 | UAP1 | 3060093 | 4680 | 0.243 | -0.0574 | No | ||
43 | SPEN | 2060041 | 4697 | 0.241 | -0.0571 | No | ||
44 | PPP2R5C | 3310121 6650672 | 4724 | 0.238 | -0.0575 | No | ||
45 | DDIT4 | 2570408 | 4765 | 0.234 | -0.0586 | No | ||
46 | CENPA | 5080154 | 4878 | 0.221 | -0.0636 | No | ||
47 | PAFAH1B1 | 4230333 6420121 6450066 | 4946 | 0.213 | -0.0663 | No | ||
48 | SPRED2 | 510138 540195 | 5050 | 0.201 | -0.0710 | No | ||
49 | CD2AP | 1940369 | 5498 | 0.159 | -0.0946 | No | ||
50 | TRIM32 | 4150332 | 5537 | 0.157 | -0.0959 | No | ||
51 | ARID5B | 110403 | 5631 | 0.150 | -0.1003 | No | ||
52 | TUBGCP3 | 4920563 | 5692 | 0.145 | -0.1029 | No | ||
53 | DLX2 | 2320438 4200673 | 5721 | 0.143 | -0.1037 | No | ||
54 | CYR61 | 1240408 5290026 4120452 6550008 | 5791 | 0.138 | -0.1069 | No | ||
55 | FZD7 | 7050706 | 5831 | 0.136 | -0.1084 | No | ||
56 | CXCL12 | 580546 4150750 4570068 | 5956 | 0.127 | -0.1145 | No | ||
57 | KIF2A | 3990286 6130575 | 6089 | 0.119 | -0.1212 | No | ||
58 | PKP4 | 3710400 5890097 | 6121 | 0.117 | -0.1223 | No | ||
59 | FOSL2 | 870044 1230427 6520433 | 6149 | 0.116 | -0.1232 | No | ||
60 | BCAR3 | 1660717 | 6388 | 0.102 | -0.1357 | No | ||
61 | NCK1 | 6200575 6510050 | 6429 | 0.100 | -0.1374 | No | ||
62 | THBS1 | 4560494 430288 | 6484 | 0.098 | -0.1399 | No | ||
63 | HMGA2 | 2940121 3390647 5130279 6400136 | 6643 | 0.091 | -0.1481 | No | ||
64 | ZFP36L2 | 510180 | 6657 | 0.091 | -0.1484 | No | ||
65 | CTDSP2 | 5340315 5690133 | 6954 | 0.079 | -0.1641 | No | ||
66 | MLX | 1770450 7040452 | 7013 | 0.077 | -0.1669 | No | ||
67 | AGTR1 | 4780524 2680592 | 7248 | 0.070 | -0.1793 | No | ||
68 | CNOT2 | 520546 2060397 4610543 5550113 | 7406 | 0.064 | -0.1875 | No | ||
69 | CDK7 | 2640451 | 7569 | 0.060 | -0.1961 | No | ||
70 | BNIP2 | 1410475 6770088 | 8095 | 0.048 | -0.2244 | No | ||
71 | GREM1 | 3940180 | 8441 | 0.041 | -0.2430 | No | ||
72 | POLE2 | 6110041 | 8692 | 0.035 | -0.2564 | No | ||
73 | POGZ | 870348 7040286 | 8779 | 0.033 | -0.2609 | No | ||
74 | SS18 | 1940440 2900072 6900129 | 8987 | 0.029 | -0.2721 | No | ||
75 | STK38 | 7100114 | 9033 | 0.028 | -0.2744 | No | ||
76 | SMAD7 | 430377 | 9300 | 0.023 | -0.2887 | No | ||
77 | IRS1 | 1190204 | 9325 | 0.023 | -0.2899 | No | ||
78 | CTGF | 4540577 | 9479 | 0.020 | -0.2982 | No | ||
79 | EPS8 | 7050204 | 9837 | 0.014 | -0.3175 | No | ||
80 | SATB2 | 2470181 | 9856 | 0.014 | -0.3184 | No | ||
81 | YY1 | 6130451 | 10098 | 0.010 | -0.3315 | No | ||
82 | SAMD4A | 1170717 | 10258 | 0.007 | -0.3401 | No | ||
83 | CKS2 | 1410156 | 10263 | 0.007 | -0.3403 | No | ||
84 | GAS1 | 2120504 | 10281 | 0.007 | -0.3412 | No | ||
85 | NUP153 | 7000452 | 10430 | 0.004 | -0.3492 | No | ||
86 | PDE4B | 4480121 | 10495 | 0.003 | -0.3527 | No | ||
87 | NR2F2 | 3170609 3310577 | 10615 | 0.001 | -0.3591 | No | ||
88 | RRS1 | 4560551 | 10776 | -0.002 | -0.3678 | No | ||
89 | PNN | 6650504 | 10785 | -0.002 | -0.3682 | No | ||
90 | PUM2 | 4200441 5910446 | 10923 | -0.004 | -0.3757 | No | ||
91 | SERTAD2 | 2810673 6840450 | 10958 | -0.005 | -0.3775 | No | ||
92 | PLEKHC1 | 2650066 | 10996 | -0.005 | -0.3795 | No | ||
93 | XPO1 | 540707 | 11124 | -0.008 | -0.3864 | No | ||
94 | ARHGEF7 | 1690441 | 11219 | -0.009 | -0.3914 | No | ||
95 | TLE4 | 1450064 1500519 | 11293 | -0.010 | -0.3954 | No | ||
96 | MFAP1 | 6660092 | 11338 | -0.011 | -0.3977 | No | ||
97 | SLBP | 6220601 | 11603 | -0.016 | -0.4120 | No | ||
98 | VEGFC | 5910494 | 11694 | -0.018 | -0.4168 | No | ||
99 | GEM | 5290082 | 11728 | -0.019 | -0.4185 | No | ||
100 | GATA2 | 6590280 | 11962 | -0.024 | -0.4311 | No | ||
101 | TIPARP | 50397 | 12055 | -0.026 | -0.4359 | No | ||
102 | SCHIP1 | 4560152 | 12061 | -0.026 | -0.4361 | No | ||
103 | FHL5 | 430400 | 12167 | -0.028 | -0.4417 | No | ||
104 | ZFAND5 | 6770673 | 12271 | -0.030 | -0.4471 | No | ||
105 | DR1 | 5860750 | 12291 | -0.031 | -0.4480 | No | ||
106 | RND3 | 940504 | 12509 | -0.036 | -0.4597 | No | ||
107 | EDG2 | 6290215 | 12557 | -0.038 | -0.4620 | No | ||
108 | FGF5 | 5270204 | 12662 | -0.041 | -0.4675 | No | ||
109 | TSPAN5 | 6770019 | 12666 | -0.041 | -0.4675 | No | ||
110 | TM4SF1 | 2570021 | 12718 | -0.042 | -0.4701 | No | ||
111 | PODXL | 130717 | 13232 | -0.059 | -0.4977 | No | ||
112 | STXBP3 | 780706 | 13297 | -0.062 | -0.5009 | No | ||
113 | GNAI1 | 4560390 | 13389 | -0.065 | -0.5055 | No | ||
114 | IDI1 | 1450736 | 13648 | -0.078 | -0.5192 | No | ||
115 | STK24 | 6760484 | 13657 | -0.079 | -0.5193 | No | ||
116 | SSH1 | 7000538 | 13672 | -0.081 | -0.5197 | No | ||
117 | HMGB2 | 2640603 | 13760 | -0.085 | -0.5240 | No | ||
118 | PFTK1 | 1780181 | 13767 | -0.086 | -0.5239 | No | ||
119 | CSTF3 | 3850156 5570458 | 13768 | -0.086 | -0.5235 | No | ||
120 | FYN | 2100468 4760520 4850687 | 13831 | -0.091 | -0.5265 | No | ||
121 | STAM | 3850008 4760441 | 14012 | -0.104 | -0.5358 | No | ||
122 | TOPBP1 | 6020333 | 14021 | -0.105 | -0.5358 | No | ||
123 | MET | 2690348 | 14137 | -0.115 | -0.5415 | No | ||
124 | PIP5K3 | 5360112 | 14309 | -0.134 | -0.5502 | No | ||
125 | DUSP1 | 6860121 | 14399 | -0.144 | -0.5543 | No | ||
126 | ITGA6 | 3830129 | 14632 | -0.181 | -0.5661 | No | ||
127 | AMD1 | 6290128 | 14673 | -0.188 | -0.5674 | No | ||
128 | CCNG1 | 870402 1500685 6110594 | 14759 | -0.206 | -0.5711 | No | ||
129 | PDGFRA | 2940332 | 14915 | -0.239 | -0.5784 | No | ||
130 | BACH1 | 290195 | 14954 | -0.249 | -0.5794 | No | ||
131 | EIF4E | 1580403 70133 6380215 | 15012 | -0.264 | -0.5813 | No | ||
132 | WEE1 | 3390070 | 15186 | -0.317 | -0.5892 | No | ||
133 | KRIT1 | 2640500 4230435 4730184 | 15213 | -0.328 | -0.5891 | No | ||
134 | BMPR1A | 2190193 4060603 | 15240 | -0.335 | -0.5890 | No | ||
135 | E2F3 | 50162 460180 | 15296 | -0.350 | -0.5904 | No | ||
136 | NRIP1 | 3190039 | 15347 | -0.369 | -0.5914 | No | ||
137 | CITED2 | 5670114 5130088 | 15380 | -0.379 | -0.5914 | No | ||
138 | GBAS | 6760278 | 15389 | -0.383 | -0.5901 | No | ||
139 | CBX3 | 1780592 3940008 | 15485 | -0.413 | -0.5933 | No | ||
140 | BRD8 | 1170463 2900075 4050397 6590332 | 15540 | -0.432 | -0.5943 | Yes | ||
141 | NFE2L2 | 2810619 3390162 | 15541 | -0.432 | -0.5923 | Yes | ||
142 | CCNA2 | 5290075 | 15560 | -0.440 | -0.5913 | Yes | ||
143 | SQLE | 50180 940092 | 15568 | -0.445 | -0.5896 | Yes | ||
144 | STRN3 | 1450093 6200685 | 15595 | -0.454 | -0.5890 | Yes | ||
145 | IL4R | 2370520 | 15612 | -0.462 | -0.5877 | Yes | ||
146 | ACVR1B | 3610446 5570195 | 15636 | -0.471 | -0.5868 | Yes | ||
147 | NTF3 | 5890131 | 15719 | -0.500 | -0.5890 | Yes | ||
148 | CASP3 | 6620397 | 15812 | -0.538 | -0.5915 | Yes | ||
149 | CDC6 | 4570296 5360600 | 15903 | -0.578 | -0.5937 | Yes | ||
150 | RAB11A | 5360079 | 15951 | -0.603 | -0.5935 | Yes | ||
151 | SMURF2 | 1940161 | 15992 | -0.622 | -0.5929 | Yes | ||
152 | STX3 | 1190563 2640215 | 16058 | -0.650 | -0.5934 | Yes | ||
153 | ADM | 4810121 | 16121 | -0.679 | -0.5937 | Yes | ||
154 | PDCD10 | 4760500 | 16165 | -0.708 | -0.5928 | Yes | ||
155 | PPP1R12A | 4070066 4590162 | 16223 | -0.748 | -0.5924 | Yes | ||
156 | RHOB | 1500309 | 16244 | -0.756 | -0.5900 | Yes | ||
157 | DYRK1A | 3190181 | 16263 | -0.763 | -0.5875 | Yes | ||
158 | NCOA3 | 4540195 | 16332 | -0.802 | -0.5875 | Yes | ||
159 | COIL | 4480408 | 16350 | -0.809 | -0.5848 | Yes | ||
160 | BHLHB2 | 7040603 | 16464 | -0.878 | -0.5869 | Yes | ||
161 | DUSP11 | 1500088 4610280 | 16503 | -0.897 | -0.5848 | Yes | ||
162 | CASP8 | 4850154 | 16519 | -0.907 | -0.5815 | Yes | ||
163 | FUS | 4760619 | 16558 | -0.935 | -0.5792 | Yes | ||
164 | MAT2A | 4070026 4730079 6020280 | 16565 | -0.938 | -0.5753 | Yes | ||
165 | RAD21 | 1990278 | 16575 | -0.945 | -0.5714 | Yes | ||
166 | TNFRSF1A | 1090390 6520735 | 16601 | -0.957 | -0.5684 | Yes | ||
167 | ARL4C | 1190279 | 16610 | -0.961 | -0.5644 | Yes | ||
168 | RNF4 | 580286 1400152 | 16656 | -0.986 | -0.5623 | Yes | ||
169 | RBM5 | 3520402 5270121 | 16681 | -0.998 | -0.5591 | Yes | ||
170 | DICER1 | 540286 | 16696 | -1.001 | -0.5552 | Yes | ||
171 | SEC24B | 460717 3060040 | 16731 | -1.021 | -0.5524 | Yes | ||
172 | AURKA | 780537 | 16736 | -1.026 | -0.5479 | Yes | ||
173 | TPST1 | 2570358 | 16763 | -1.043 | -0.5446 | Yes | ||
174 | REV3L | 1090717 | 16793 | -1.065 | -0.5412 | Yes | ||
175 | BLCAP | 3990253 | 16853 | -1.099 | -0.5394 | Yes | ||
176 | ATP6V1B2 | 4060528 | 17047 | -1.268 | -0.5441 | Yes | ||
177 | RIPK1 | 3190025 | 17073 | -1.297 | -0.5395 | Yes | ||
178 | CDR2 | 6200377 | 17137 | -1.366 | -0.5367 | Yes | ||
179 | SLC20A2 | 5700577 | 17201 | -1.427 | -0.5335 | Yes | ||
180 | KLF9 | 3840022 | 17293 | -1.526 | -0.5315 | Yes | ||
181 | EMG1 | 50286 380242 | 17300 | -1.532 | -0.5248 | Yes | ||
182 | CUL1 | 1990632 | 17375 | -1.620 | -0.5214 | Yes | ||
183 | HMGCR | 2630242 | 17408 | -1.661 | -0.5155 | Yes | ||
184 | CHD1 | 4590048 | 17440 | -1.692 | -0.5094 | Yes | ||
185 | TOP2A | 360717 | 17451 | -1.703 | -0.5021 | Yes | ||
186 | MAPK14 | 5290731 | 17476 | -1.736 | -0.4955 | Yes | ||
187 | SNX4 | 1980358 | 17507 | -1.769 | -0.4890 | Yes | ||
188 | TLE1 | 540390 1580309 3710019 | 17508 | -1.770 | -0.4809 | Yes | ||
189 | RUNX1 | 3840711 | 17573 | -1.837 | -0.4759 | Yes | ||
190 | STX7 | 5910484 | 17600 | -1.871 | -0.4688 | Yes | ||
191 | PRKCD | 770592 | 17650 | -1.931 | -0.4626 | Yes | ||
192 | ATP2A2 | 1090075 3990279 | 17677 | -1.987 | -0.4549 | Yes | ||
193 | TLK2 | 1170161 | 17708 | -2.029 | -0.4472 | Yes | ||
194 | PHTF2 | 6590053 | 17751 | -2.090 | -0.4399 | Yes | ||
195 | TAF11 | 5720538 | 17773 | -2.118 | -0.4313 | Yes | ||
196 | RAF1 | 1770600 | 17834 | -2.195 | -0.4245 | Yes | ||
197 | UGCG | 3420053 | 17861 | -2.234 | -0.4157 | Yes | ||
198 | SFRS3 | 770315 4230593 | 17869 | -2.240 | -0.4058 | Yes | ||
199 | TNFAIP8 | 2760551 | 17876 | -2.248 | -0.3958 | Yes | ||
200 | TBL1X | 6400524 | 17890 | -2.280 | -0.3860 | Yes | ||
201 | KIF23 | 5570112 | 17948 | -2.363 | -0.3783 | Yes | ||
202 | TNFAIP3 | 2900142 | 17951 | -2.367 | -0.3675 | Yes | ||
203 | BMI1 | 3830026 2630204 | 17954 | -2.375 | -0.3568 | Yes | ||
204 | ZBED4 | 770441 | 18009 | -2.477 | -0.3483 | Yes | ||
205 | RYBP | 60746 | 18116 | -2.714 | -0.3416 | Yes | ||
206 | DDX3X | 2190020 | 18122 | -2.725 | -0.3294 | Yes | ||
207 | MARCKS | 7040450 | 18164 | -2.808 | -0.3188 | Yes | ||
208 | CRKL | 4050427 | 18201 | -2.887 | -0.3075 | Yes | ||
209 | KPNA2 | 3450114 | 18222 | -2.961 | -0.2950 | Yes | ||
210 | MPHOSPH6 | 5570164 | 18246 | -3.011 | -0.2824 | Yes | ||
211 | NASP | 2260139 2940369 5130707 | 18304 | -3.185 | -0.2709 | Yes | ||
212 | GTF2E1 | 4070014 | 18358 | -3.384 | -0.2583 | Yes | ||
213 | RAB1A | 2370671 | 18364 | -3.405 | -0.2429 | Yes | ||
214 | EMP1 | 4120438 | 18396 | -3.541 | -0.2284 | Yes | ||
215 | RARS | 380390 | 18406 | -3.585 | -0.2124 | Yes | ||
216 | PITPNB | 5130039 | 18413 | -3.593 | -0.1963 | Yes | ||
217 | TLK1 | 7100605 | 18433 | -3.696 | -0.1803 | Yes | ||
218 | THUMPD1 | 7510148 | 18482 | -3.939 | -0.1649 | Yes | ||
219 | UBE2G1 | 2230546 5420528 7040463 | 18536 | -4.350 | -0.1478 | Yes | ||
220 | SPOP | 450035 | 18556 | -4.589 | -0.1278 | Yes | ||
221 | NFYB | 1850053 | 18567 | -4.754 | -0.1065 | Yes | ||
222 | MAPK6 | 6760520 | 18578 | -4.847 | -0.0848 | Yes | ||
223 | RAB14 | 6860139 | 18595 | -5.314 | -0.0613 | Yes | ||
224 | LBR | 4540671 | 18614 | -6.656 | -0.0318 | Yes | ||
225 | PTK2 | 1780148 | 18615 | -6.937 | 0.0001 | Yes |