Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_03_absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls #truncNotch_versus_absentNotch |
| Phenotype | phenotype_absentNotch_versus_truncNotch.cls#truncNotch_versus_absentNotch |
| Upregulated in class | absentNotch |
| GeneSet | SANSOM_APC_LOSS5_UP |
| Enrichment Score (ES) | -0.68488497 |
| Normalized Enrichment Score (NES) | -1.874376 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0051825037 |
| FWER p-Value | 0.016 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | GRWD1 | 6350528 | 405 | 2.926 | 0.0155 | No | ||
| 2 | SMYD5 | 6220025 | 1075 | 1.940 | 0.0041 | No | ||
| 3 | CDK9 | 630707 | 1709 | 1.447 | -0.0116 | No | ||
| 4 | SLC27A1 | 6110093 | 1831 | 1.324 | -0.0012 | No | ||
| 5 | ZBTB17 | 6220082 | 2057 | 1.168 | 0.0016 | No | ||
| 6 | KCNQ1 | 1580050 6860441 | 2448 | 0.942 | -0.0074 | No | ||
| 7 | MDFI | 6200041 | 3273 | 0.546 | -0.0449 | No | ||
| 8 | TNFRSF19 | 3870731 6940730 | 4231 | 0.313 | -0.0926 | No | ||
| 9 | CD44 | 3990072 4850671 5860411 6860148 7050551 | 4341 | 0.293 | -0.0947 | No | ||
| 10 | KCND2 | 1170128 2100112 | 4632 | 0.250 | -0.1072 | No | ||
| 11 | DDIT4 | 2570408 | 4765 | 0.234 | -0.1113 | No | ||
| 12 | ZZZ3 | 780133 2320239 2640452 5080706 6550341 | 5399 | 0.167 | -0.1433 | No | ||
| 13 | HDC | 4150463 | 5408 | 0.166 | -0.1416 | No | ||
| 14 | PLA2G2A | 3190458 | 6080 | 0.120 | -0.1763 | No | ||
| 15 | CEBPZ | 2970053 2680068 | 6146 | 0.116 | -0.1784 | No | ||
| 16 | KIF20A | 2650050 | 6291 | 0.108 | -0.1847 | No | ||
| 17 | MMP7 | 1780497 | 6700 | 0.089 | -0.2056 | No | ||
| 18 | 2300002G24RIK | 2320040 | 7504 | 0.062 | -0.2481 | No | ||
| 19 | FGFR4 | 2650072 | 7609 | 0.059 | -0.2530 | No | ||
| 20 | ANP32B | 940095 2450494 4200368 | 8398 | 0.041 | -0.2950 | No | ||
| 21 | MYO1B | 770372 | 8443 | 0.041 | -0.2969 | No | ||
| 22 | HELLS | 4560086 4810025 | 8938 | 0.030 | -0.3231 | No | ||
| 23 | TGFBR1 | 1400148 4280020 6550711 | 9349 | 0.022 | -0.3450 | No | ||
| 24 | 1110014J01RIK | 1980332 | 9663 | 0.017 | -0.3616 | No | ||
| 25 | TSPAN12 | 4120010 | 9797 | 0.015 | -0.3686 | No | ||
| 26 | FAM60A | 3940092 | 9860 | 0.014 | -0.3718 | No | ||
| 27 | ADAM8 | 450347 5670609 | 9872 | 0.013 | -0.3722 | No | ||
| 28 | PLA2G12A | 1740463 4010066 4050348 | 10823 | -0.002 | -0.4234 | No | ||
| 29 | 9630050M13RIK | 2370086 | 11298 | -0.011 | -0.4489 | No | ||
| 30 | REPS1 | 2320603 2510333 | 11365 | -0.012 | -0.4523 | No | ||
| 31 | ZFP97 | 520324 | 11461 | -0.014 | -0.4572 | No | ||
| 32 | PTBP2 | 1240398 | 11891 | -0.022 | -0.4801 | No | ||
| 33 | CITED1 | 2350670 | 11934 | -0.023 | -0.4821 | No | ||
| 34 | PKP1 | 1500433 | 11979 | -0.024 | -0.4841 | No | ||
| 35 | SYNCRIP | 1690195 3140113 4670279 | 12501 | -0.036 | -0.5118 | No | ||
| 36 | KIF5A | 510435 | 13009 | -0.052 | -0.5385 | No | ||
| 37 | BTC | 3190133 | 13124 | -0.055 | -0.5439 | No | ||
| 38 | RNF149 | 5270494 | 13181 | -0.057 | -0.5462 | No | ||
| 39 | EPHB3 | 6650341 | 13184 | -0.057 | -0.5456 | No | ||
| 40 | SEMA3C | 7000020 | 13391 | -0.066 | -0.5559 | No | ||
| 41 | NUP54 | 940546 2360156 4060278 | 13556 | -0.073 | -0.5638 | No | ||
| 42 | LAMC2 | 450692 2680041 4200059 4670148 | 13987 | -0.102 | -0.5857 | No | ||
| 43 | FOXA2 | 540338 5860441 | 14063 | -0.108 | -0.5883 | No | ||
| 44 | OLFR91 | 6290020 | 14614 | -0.177 | -0.6158 | No | ||
| 45 | TXNL4A | 4120286 6510242 | 14746 | -0.204 | -0.6202 | No | ||
| 46 | ORC2L | 1990470 6510019 | 14885 | -0.231 | -0.6247 | No | ||
| 47 | RIN2 | 2450184 | 14893 | -0.234 | -0.6221 | No | ||
| 48 | ZRF1 | 6020181 6510484 | 15127 | -0.297 | -0.6309 | No | ||
| 49 | MYC | 380541 4670170 | 15244 | -0.337 | -0.6329 | No | ||
| 50 | FUSIP1 | 520082 5390114 | 15473 | -0.410 | -0.6399 | No | ||
| 51 | CD24 | 1780091 | 15684 | -0.485 | -0.6451 | No | ||
| 52 | IFIT2 | 4810735 | 15858 | -0.558 | -0.6473 | No | ||
| 53 | MAP4K4 | 2360059 | 16556 | -0.933 | -0.6730 | Yes | ||
| 54 | RNF4 | 580286 1400152 | 16656 | -0.986 | -0.6657 | Yes | ||
| 55 | ZFP90 | 580121 | 16683 | -0.998 | -0.6544 | Yes | ||
| 56 | SRR | 1190465 3800494 | 16737 | -1.027 | -0.6442 | Yes | ||
| 57 | PRIM2A | 7000692 | 16825 | -1.081 | -0.6351 | Yes | ||
| 58 | ETS2 | 360451 | 16900 | -1.141 | -0.6245 | Yes | ||
| 59 | 1190002H23RIK | 4480128 | 16944 | -1.171 | -0.6119 | Yes | ||
| 60 | PES1 | 2470427 | 17113 | -1.335 | -0.6039 | Yes | ||
| 61 | GNL2 | 6620022 | 17133 | -1.362 | -0.5876 | Yes | ||
| 62 | TIAM1 | 5420288 | 17196 | -1.424 | -0.5727 | Yes | ||
| 63 | EIF4G2 | 3800575 6860184 | 17237 | -1.470 | -0.5561 | Yes | ||
| 64 | NCL | 2360463 4540279 | 17306 | -1.541 | -0.5401 | Yes | ||
| 65 | 4930573I19RIK | 5270402 | 17308 | -1.544 | -0.5205 | Yes | ||
| 66 | COPS2 | 3060142 | 17384 | -1.637 | -0.5037 | Yes | ||
| 67 | UTP14A | 6590048 | 17442 | -1.694 | -0.4851 | Yes | ||
| 68 | FEM1B | 1230110 | 17452 | -1.704 | -0.4639 | Yes | ||
| 69 | CIRH1A | 2340372 | 17621 | -1.892 | -0.4488 | Yes | ||
| 70 | NOL5 | 580731 | 17671 | -1.978 | -0.4262 | Yes | ||
| 71 | SOX4 | 2260091 | 17681 | -1.992 | -0.4013 | Yes | ||
| 72 | EIF1 | 5080100 | 17780 | -2.124 | -0.3795 | Yes | ||
| 73 | HK2 | 2640722 | 17846 | -2.214 | -0.3548 | Yes | ||
| 74 | NSUN2 | 2120193 | 17940 | -2.354 | -0.3297 | Yes | ||
| 75 | ETF1 | 6770075 | 17996 | -2.447 | -0.3015 | Yes | ||
| 76 | DDX21 | 6100446 | 18207 | -2.918 | -0.2756 | Yes | ||
| 77 | HNRPAB | 540504 | 18350 | -3.358 | -0.2404 | Yes | ||
| 78 | PRKRIR | 2370402 | 18374 | -3.448 | -0.1977 | Yes | ||
| 79 | GNL3 | 4050338 4810500 | 18418 | -3.608 | -0.1540 | Yes | ||
| 80 | FTSJ3 | 3140100 | 18453 | -3.783 | -0.1075 | Yes | ||
| 81 | CDCA7 | 3060097 | 18498 | -4.044 | -0.0583 | Yes | ||
| 82 | 2810037C14RIK | 5290575 | 18587 | -5.066 | 0.0016 | Yes |
