Details for gene set SANSOM_APC_5

Table: GSEA Results Summary

Dataset	Set_03_absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls #truncNotch_versus_absentNotch
Phenotype	phenotype_absentNotch_versus_truncNotch.cls#truncNotch_versus_absentNotch
Upregulated in class	truncNotch
GeneSet	SANSOM_APC_5_DN
Enrichment Score (ES)	0.527622
Normalized Enrichment Score (NES)	1.6174724
Nominal p-value	0.0
FDR q-value	0.213721
FWER p-Value	0.922

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	CD5	6590338	9	6.037	0.0199	Yes
2	DTX1	5900372	23	5.496	0.0377	Yes
3	ANXA6	2190014	30	5.135	0.0547	Yes
4	ADAM19	5340075	53	4.666	0.0692	Yes
5	CD6	4150035 5570368	101	4.101	0.0805	Yes
6	CD82	4780711	112	4.006	0.0934	Yes
7	CD160	4210377	113	3.999	0.1069	Yes
8	IRF1	2340152 3450592 6290121 6980577	118	3.979	0.1201	Yes
9	CD2	430672	120	3.932	0.1333	Yes
10	RAC2	1580541	142	3.829	0.1451	Yes
11	CORO1A	3140609 3190020 3190037	170	3.635	0.1558	Yes
12	PRPSAP1	6980494	180	3.595	0.1675	Yes
13	POU2AF1	5690242	230	3.410	0.1763	Yes
14	GPSM3	2690154	244	3.370	0.1869	Yes
15	ABCD1	5670373	248	3.366	0.1981	Yes
16	CD3D	2810739	251	3.343	0.2093	Yes
17	VAMP5	3830300	269	3.288	0.2194	Yes
18	IGH-6	5720193 6550075	284	3.247	0.2296	Yes
19	IL2RB	4730072	309	3.163	0.2390	Yes
20	TCTA	2680687	315	3.141	0.2493	Yes
21	CST7	380369	333	3.093	0.2588	Yes
22	ZAP70	1410494 2260504	358	3.049	0.2677	Yes
23	S100A13	520019	362	3.031	0.2778	Yes
24	MGST2	2650129	379	2.986	0.2870	Yes
25	CD79B	1450066 3390358	411	2.900	0.2951	Yes
26	PSMB8	2850707	459	2.786	0.3019	Yes
27	GNA11	2760156 6550671 7100068	463	2.777	0.3111	Yes
28	EPHX2	2970341	469	2.770	0.3202	Yes
29	ITGAL	1450324	514	2.682	0.3268	Yes
30	GNPDA1	580181 5220112 840731	623	2.529	0.3294	Yes
31	DHRS1	5220673	694	2.425	0.3338	Yes
32	RGS10	2340292	711	2.399	0.3410	Yes
33	ACP5	2230717	713	2.396	0.3490	Yes
34	H2-K1	580332	720	2.373	0.3567	Yes
35	TCAP	4890446	800	2.264	0.3600	Yes
36	PIK3CD	3060546	809	2.251	0.3671	Yes
37	CTSW	360368	823	2.238	0.3740	Yes
38	WDTC1	1690541	886	2.157	0.3778	Yes
39	TAX1BP3	940706 6100687 6220176	888	2.155	0.3851	Yes
40	ACY3	6110369	953	2.065	0.3885	Yes
41	ITGB2	6380348	968	2.051	0.3947	Yes
42	PDZK1	2320128	969	2.051	0.4016	Yes
43	FMNL1	5860347	1022	1.999	0.4055	Yes
44	DGAT1	1850538	1070	1.947	0.4095	Yes
45	PRRG2	4540095	1119	1.899	0.4132	Yes
46	ITGB7	4670619	1187	1.843	0.4158	Yes
47	GSTA4	1660369	1233	1.791	0.4194	Yes
48	ARHGDIB	4730433	1251	1.773	0.4244	Yes
49	ACE	1780161 4920315	1326	1.718	0.4262	Yes
50	IL12RB1	2230338 5420053	1336	1.710	0.4314	Yes
51	CD3G	2680288	1343	1.703	0.4369	Yes
52	CYB5R3	430097 6860400	1348	1.695	0.4423	Yes
53	ABHD8	6660082	1358	1.683	0.4475	Yes
54	SIRT2	630494	1423	1.629	0.4495	Yes
55	SLC35B1	5700064 7000735	1445	1.609	0.4538	Yes
56	SLC27A4	4060139	1489	1.578	0.4568	Yes
57	KEAP1	1570121 2900546 3840576	1510	1.564	0.4609	Yes
58	CD72	2340369	1531	1.549	0.4651	Yes
59	CYP4F13	3170132	1554	1.532	0.4690	Yes
60	SIPA1	5220687	1613	1.500	0.4709	Yes
61	IGH-VJ558	60025 1690184	1632	1.490	0.4750	Yes
62	SLPI	2120446	1704	1.450	0.4760	Yes
63	CDKN2D	6040035	1746	1.413	0.4785	Yes
64	IGK-V1	70300 4050673	1804	1.349	0.4799	Yes
65	ARSA	5570717	1823	1.331	0.4834	Yes
66	PLTP	630110 130497 4050139	1851	1.313	0.4864	Yes
67	CENPJ	6660551 4670592	1875	1.296	0.4895	Yes
68	A230106M15RIK	5270435	1894	1.280	0.4928	Yes
69	NAPSA	4810711 5910364	1899	1.277	0.4969	Yes
70	FLT3L	5130092	1946	1.245	0.4986	Yes
71	FGD3	5690465	1956	1.236	0.5022	Yes
72	CD3E	3800056	2032	1.180	0.5021	Yes
73	SULT2B1	3360484 4810181	2047	1.172	0.5053	Yes
74	HAGH	540358	2092	1.148	0.5068	Yes
75	GPX4	5080433	2108	1.138	0.5098	Yes
76	IGL-V1	2510725 4120037	2128	1.124	0.5125	Yes
77	RFXANK	4010341	2145	1.106	0.5154	Yes
78	CASP7	4210156	2149	1.104	0.5189	Yes
79	SLC35C2	770707 5690603	2254	1.045	0.5168	Yes
80	STK10	2760010 3940605	2261	1.039	0.5199	Yes
81	MOV10	50673 430577 3870280	2291	1.024	0.5218	Yes
82	SPHK2	2030487 4120670 4850114	2308	1.017	0.5244	Yes
83	SLC11A2	3140603	2312	1.014	0.5276	Yes
84	CPT2	3940504 6180075	2421	0.955	0.5249	No
85	INPP5D	3450731	2483	0.919	0.5247	No
86	TM4SF5	3120280	2532	0.888	0.5251	No
87	CD7	3140465	2564	0.870	0.5263	No
88	ATP6V0B	2810112	2594	0.857	0.5276	No
89	BTD	2640338	2712	0.793	0.5239	No
90	IL12RB2	6020465	2779	0.761	0.5228	No
91	SMPD2	2370133	2861	0.710	0.5208	No
92	EVI2A	6840110	2897	0.693	0.5212	No
93	CRAT	540020 2060364 3520148	2919	0.683	0.5224	No
94	IKBKE	1850332	2921	0.681	0.5246	No
95	ST3GAL4	6350020	2979	0.656	0.5237	No
96	POLR2I	4060400	3041	0.633	0.5225	No
97	PPAP2A	1170397 3440288 3930270	3063	0.624	0.5234	No
98	DPT	5670731	3067	0.623	0.5254	No
99	CD53	5550162	3096	0.609	0.5259	No
100	MXI1	5050064 5130484	3155	0.590	0.5247	No
101	ATP6V0A1	1570082 3870441 4230044	3306	0.536	0.5183	No
102	KLRB1C	4050022	3319	0.530	0.5194	No
103	CXCL13	6290402	3382	0.512	0.5178	No
104	TGFB1	1940162	3412	0.500	0.5179	No
105	GDI1	4590400 5290358 6020687 6180446	3413	0.500	0.5196	No
106	FAS	4480112 6110040	3448	0.488	0.5194	No
107	CYP2S1	2970725	3513	0.467	0.5174	No
108	MTF2	50333	3610	0.438	0.5136	No
109	GPR89A	780315 1580368	3639	0.432	0.5136	No
110	PPAPDC1A	4560017	3695	0.419	0.5120	No
111	RHOC	2060242	3771	0.401	0.5092	No
112	SELPL	1770167	3776	0.399	0.5103	No
113	SOAT2	1230324 3610603	3810	0.393	0.5099	No
114	TEP1	7040735	3878	0.377	0.5075	No
115	LAT2	5340440	3994	0.354	0.5024	No
116	ST8SIA4	2680605 3060215	4127	0.330	0.4963	No
117	AGR2	3990161	4152	0.324	0.4960	No
118	LSP1	2350091	4260	0.307	0.4912	No
119	RDH5	2970736 3940632 5340730 6370093 4610059	4262	0.307	0.4922	No
120	CIDEB	3360274	4319	0.296	0.4901	No
121	PCOLCE	4210433	4338	0.294	0.4901	No
122	GNAZ	6130296	4339	0.293	0.4911	No
123	IL4I1	3190161	4360	0.291	0.4910	No
124	G6PC	430093	4365	0.289	0.4918	No
125	ERCC5	770025 4540692	4452	0.275	0.4880	No
126	OGN	3710326 3800193	4467	0.273	0.4882	No
127	SLC2A2	5130537 5720722 6770079	4490	0.270	0.4879	No
128	PCX	2690750	4651	0.248	0.4799	No
129	RUNX2	1400193 4230215	4693	0.241	0.4785	No
130	1810020D17RIK	5900035	4761	0.234	0.4756	No
131	CCL21B	4670176	4854	0.225	0.4714	No
132	ABCC2	380202 5390300	4990	0.208	0.4647	No
133	CD79A	3450563	4993	0.208	0.4653	No
134	ABCC3	4050242	5094	0.194	0.4604	No
135	GZMA	3390315	5137	0.189	0.4588	No
136	GALM	730368	5162	0.187	0.4581	No
137	GSTT1	5290520	5285	0.176	0.4520	No
138	C1QB	5910292	5308	0.174	0.4514	No
139	CEACAM10	4730706	5322	0.173	0.4513	No
140	KCNJ11	2510131	5366	0.169	0.4495	No
141	IRF4	610133	5497	0.159	0.4429	No
142	CAPN9	3450097 5910687	5513	0.158	0.4426	No
143	GPD1	2480095	5576	0.154	0.4397	No
144	CNTNAP1	6650132	5593	0.153	0.4394	No
145	DGKA	5720152 5890328	5640	0.149	0.4374	No
146	UPP1	3850358 3940100	5715	0.143	0.4338	No
147	THEM2	6840746	5742	0.142	0.4329	No
148	ENTPD2	4590739	5819	0.136	0.4292	No
149	SOD3	1410484	5947	0.127	0.4226	No
150	PRLR	1980647 1990097	5976	0.125	0.4215	No
151	RASSF2	2480079 5720546	5991	0.124	0.4212	No
152	CIDEC	3450372	6122	0.117	0.4145	No
153	REG1	7400528	6130	0.117	0.4145	No
154	SEPT4	1580593	6173	0.114	0.4126	No
155	HIC1	2650142	6201	0.113	0.4115	No
156	9830147J24RIK	2690451	6233	0.111	0.4102	No
157	LTBP4	50164 1780301	6252	0.110	0.4095	No
158	SLC4A4	1780075 1850040 4810068	6282	0.109	0.4083	No
159	1810010M01RIK	1240338	6294	0.108	0.4081	No
160	DPEP1	5080014	6336	0.105	0.4062	No
161	REG3A	4220202	6457	0.099	0.4000	No
162	SLC2A5	670273	6487	0.098	0.3987	No
163	CX3CL1	3990707	6538	0.096	0.3963	No
164	DNAJB9	460114	6640	0.091	0.3911	No
165	MCPT1	6860181	6656	0.091	0.3906	No
166	MYT1L	5670369 6660403	6775	0.086	0.3844	No
167	GCG	6220735	6776	0.086	0.3847	No
168	NR1H3	4810215 5570292	6820	0.084	0.3826	No
169	TLL1	2680315	6920	0.081	0.3775	No
170	MEP1B	1240341 5270168	6952	0.079	0.3760	No
171	BASP1	5700044	7005	0.077	0.3735	No
172	CASP6	5690239 6420551	7318	0.068	0.3566	No
173	CYP2C40	1850711	7320	0.067	0.3568	No
174	ALB1	2900309	7371	0.065	0.3543	No
175	ITGAX	6130524	7373	0.065	0.3544	No
176	ICOS	1190048	7408	0.064	0.3528	No
177	GABRB1	6760193	7422	0.064	0.3523	No
178	TMPRSS8	6620575	7536	0.061	0.3463	No
179	SOX18	2320086	7543	0.061	0.3462	No
180	GRINA	4570519	7586	0.060	0.3441	No
181	ITGAE	4210632 4670239 5340253 5420746 5690154 5700685 6770154	7676	0.058	0.3394	No
182	RDH7	670739	7696	0.057	0.3386	No
183	MYH14	4010017	7821	0.055	0.3320	No
184	DAB1	2060193 7000605	7830	0.054	0.3317	No
185	CLCA3	6510167	7904	0.053	0.3279	No
186	MUCDHL	5720056	7927	0.052	0.3269	No
187	DDR2	7050273	7929	0.052	0.3270	No
188	TCF21	2690446	8122	0.047	0.3166	No
189	BMP4	380113	8268	0.044	0.3089	No
190	VAV1	6020487	8442	0.041	0.2995	No
191	IFNA1	5390592	8464	0.040	0.2985	No
192	TRFR2	4760397 5290070	8476	0.040	0.2980	No
193	MOGAT2	60139	8547	0.038	0.2943	No
194	SLC5A1	2470053	8664	0.036	0.2881	No
195	BC052328	4210025	8671	0.036	0.2879	No
196	CYP27B1	5270114 5360010	8940	0.030	0.2733	No
197	NFIA	2760129 5860278	8960	0.030	0.2724	No
198	GHRL	2360619 6760438	9075	0.027	0.2663	No
199	CD22	3120239	9165	0.025	0.2615	No
200	FABP7	4590142	9174	0.025	0.2611	No
201	ADH4	6840301	9337	0.022	0.2523	No
202	NPDC1	2100445	9393	0.021	0.2494	No
203	CLCN2	1940021	9430	0.021	0.2475	No
204	PTPRE	1660286 2940095	9514	0.019	0.2430	No
205	VAV2	3610725 5890717	9718	0.016	0.2320	No
206	INDO	2680390	9825	0.014	0.2262	No
207	MCFD2	520576 5690017	9866	0.013	0.2241	No
208	ALDOB	4730324	10059	0.010	0.2136	No
209	FABP1	6940035	10062	0.010	0.2135	No
210	MCPT2	5340181	10119	0.009	0.2105	No
211	RBP4	4540131	10193	0.008	0.2065	No
212	PIPOX	70750	10252	0.007	0.2034	No
213	PCSK5	5720600	10261	0.007	0.2029	No
214	1200015F23RIK	7050672	10289	0.006	0.2015	No
215	SST	6590142	10354	0.005	0.1980	No
216	SLC5A11	1170348	10625	0.001	0.1832	No
217	MAPRE3	7050504	10649	0.000	0.1820	No
218	CCNA1	6290113	10698	-0.000	0.1794	No
219	PPARA	2060026	10754	-0.001	0.1763	No
220	ACOX1	1170059 3940088	10758	-0.001	0.1762	No
221	PDE9A	5130167	10867	-0.003	0.1703	No
222	ABR	610079 1170609 3610195 5670050	10897	-0.004	0.1687	No
223	CHRNG	5860273	11062	-0.007	0.1598	No
224	NPR3	1580239	11102	-0.007	0.1576	No
225	NR1I3	50026 1240673	11110	-0.007	0.1573	No
226	CCK	6370368	11275	-0.010	0.1484	No
227	GIMAP4	5570673 6550041	11467	-0.014	0.1379	No
228	NBL1	2480021	11522	-0.015	0.1350	No
229	EDN2	6760647	11703	-0.018	0.1253	No
230	GZMB	380066	11721	-0.018	0.1244	No
231	AKR1B7	5390113	11731	-0.019	0.1240	No
232	SLC7A9	5420735 5700450	11763	-0.019	0.1223	No
233	COL4A5	1340161	11785	-0.020	0.1212	No
234	NKIRAS1	2510440 5570671	11795	-0.020	0.1208	No
235	RBP2	2060097	11799	-0.020	0.1207	No
236	SLC6A4	2230372	11889	-0.022	0.1159	No
237	CYP3A25	1500348 6650427	11941	-0.023	0.1132	No
238	SLC22A4	2340707	12079	-0.026	0.1058	No
239	2310016A09RIK	2640129	12155	-0.028	0.1018	No
240	MGAT3	2260593	12321	-0.032	0.0929	No
241	IGJ	1170541	12363	-0.033	0.0907	No
242	CD48	1570647	12384	-0.033	0.0898	No
243	TRIM47	5080717	12388	-0.033	0.0897	No
244	BARX2	4480273	12488	-0.036	0.0844	No
245	PAX8	5050301 5290164	12600	-0.039	0.0785	No
246	TNFRSF17	5890408	12761	-0.043	0.0699	No
247	AADAC	6590632	12769	-0.044	0.0696	No
248	EDN3	2690722	12770	-0.044	0.0698	No
249	COL18A1	610301 4570338	12915	-0.049	0.0621	No
250	GIP	3170364	12990	-0.051	0.0582	No
251	NCF1	3850091	13282	-0.061	0.0425	No
252	CLGN	5910008	13368	-0.065	0.0380	No
253	SEC14L1	2120551 3610537	13384	-0.065	0.0374	No
254	OGDH	3840333 6350100	13513	-0.071	0.0307	No
255	FLT4	1240292 6350707	13518	-0.072	0.0307	No
256	CYFIP2	520577 6040300	13520	-0.072	0.0309	No
257	DNASE1	1190167 6840546	13584	-0.075	0.0277	No
258	GPR12	610288	13602	-0.076	0.0270	No
259	KLRA7	1780184	13687	-0.082	0.0227	No
260	XDH	6840446	13689	-0.082	0.0229	No
261	ICAM5	2350647	13741	-0.084	0.0204	No
262	LYL1	2900242	13749	-0.084	0.0203	No
263	ARG2	6940463	13780	-0.087	0.0189	No
264	NDFIP2	4070451	13804	-0.089	0.0180	No
265	ZNF467	6770372	13940	-0.098	0.0109	No
266	TPH1	780180	14035	-0.106	0.0061	No
267	GGTLA1	3140273 4920168	14109	-0.112	0.0025	No
268	CXCL14	840114 6450324	14190	-0.121	-0.0014	No
269	LRP1	6270386	14339	-0.137	-0.0091	No
270	ATP6V0A2	4050129	14343	-0.138	-0.0088	No
271	USP2	1190292 1240253 4850035	14344	-0.138	-0.0083	No
272	ABP1	1980609 60056	14350	-0.139	-0.0081	No
273	NUDT5	6940408	14358	-0.140	-0.0080	No
274	PAFAH2	3140451 5720593 6510014	14368	-0.141	-0.0080	No
275	CDKN2B	6020040	14377	-0.141	-0.0080	No
276	MYO7A	2810102	14384	-0.142	-0.0079	No
277	LY75	1990358 4590136	14406	-0.145	-0.0085	No
278	JAK2	3780528 6100692 6550577	14411	-0.147	-0.0082	No
279	ADORA2B	6860253	14464	-0.153	-0.0106	No
280	LAPTM5	5550372	14586	-0.172	-0.0166	No
281	CHPT1	4210215 6110273	14596	-0.174	-0.0165	No
282	OLFR91	6290020	14614	-0.177	-0.0169	No
283	RGS2	1090736	14637	-0.182	-0.0174	No
284	NUMB	2450735 3800253 6350040	14665	-0.187	-0.0183	No
285	SLC22A18	7050168	14953	-0.249	-0.0332	No
286	SLC7A8	380136 5690672	15001	-0.260	-0.0349	No
287	IL18	6180039	15070	-0.281	-0.0376	No
288	TRP53INP2	2690435	15073	-0.282	-0.0368	No
289	TCEA3	1770020	15102	-0.291	-0.0373	No
290	VDR	130156 510438	15287	-0.348	-0.0462	No
291	CITED2	5670114 5130088	15380	-0.379	-0.0500	No
292	BCAT2	5890112	15387	-0.382	-0.0490	No
293	MERTK	6420056	15516	-0.427	-0.0546	No
294	GGT1	610082	15561	-0.441	-0.0555	No
295	ICAM2	6400113	15617	-0.464	-0.0570	No
296	CAPN3	1980451 6940047	15666	-0.479	-0.0580	No
297	SRXN1	630731 3130195 4480239	15717	-0.500	-0.0590	No
298	TGFBI	2060446 6900112	15802	-0.534	-0.0618	No
299	CASP3	6620397	15812	-0.538	-0.0605	No
300	1810046J19RIK	3830070	15856	-0.558	-0.0610	No
301	CCL25	450541 540435	15867	-0.562	-0.0596	No
302	ST6GAL1	2970546	15923	-0.587	-0.0606	No
303	ITGA3	4570427	16116	-0.675	-0.0689	No
304	ANK3	1500161 2900435 4210154 6400100	16147	-0.695	-0.0682	No
305	CASP1	2360546	16152	-0.700	-0.0660	No
306	TYROBP	2230020	16259	-0.762	-0.0693	No
307	LTB4R	1770056	16293	-0.779	-0.0684	No
308	SEC14L2	2640370	16305	-0.786	-0.0664	No
309	GALNT10	520315 3990088	16374	-0.822	-0.0673	No
310	H2-DMB1	4760026	16422	-0.849	-0.0671	No
311	FAHD1	4670139	16433	-0.858	-0.0647	No
312	SDF4	3440519	16454	-0.872	-0.0629	No
313	ZDHHC14	3780458	16459	-0.874	-0.0601	No
314	GSTM1	1940332 6590463	16468	-0.879	-0.0576	No
315	RRAGD	670075	16472	-0.881	-0.0548	No
316	CGGBP1	4810053	16476	-0.886	-0.0520	No
317	ENTPD5	4280070	16640	-0.978	-0.0576	No
318	WBP2	3170128	16663	-0.988	-0.0555	No
319	BC011209	2360373 6330136	16669	-0.992	-0.0524	No
320	CYB5A	5080450	16804	-1.069	-0.0561	No
321	SIRPA	130465 5700332	16863	-1.108	-0.0556	No
322	PAPSS2	870113	16867	-1.112	-0.0520	No
323	5730469M10RIK	5080593	17065	-1.292	-0.0584	No
324	CDR2	6200377	17137	-1.366	-0.0577	No
325	CD52	5910242	17214	-1.440	-0.0570	No
326	HNRPA1	4670398 5050687	17220	-1.449	-0.0524	No
327	MGST3	3450338 5290736	17247	-1.479	-0.0488	No
328	ATP2A3	130440 2190451	17262	-1.495	-0.0445	No
329	MTTP	3780161	17268	-1.501	-0.0398	No
330	PTPRC	130402 5290148	17334	-1.574	-0.0380	No
331	CCL5	3710397	17429	-1.684	-0.0375	No
332	CUL4B	6900390	17475	-1.736	-0.0341	No
333	RORC	1740121	17653	-1.934	-0.0372	No
334	SAR1B	2510273	17703	-2.023	-0.0331	No
335	TOB1	4150138	17744	-2.086	-0.0283	No
336	CD28	1400739 4210093	17795	-2.145	-0.0238	No
337	6330412F12RIK	1240446	17960	-2.387	-0.0247	No
338	SETDB1	840093	17975	-2.409	-0.0173	No
339	ADIPOR2	1510035	18055	-2.558	-0.0130	No
340	ATP1B1	3130594	18138	-2.762	-0.0082	No
341	ABCB9	110603 4560592 6110338	18159	-2.801	0.0001	No
342	MAP3K1	5360347	18311	-3.211	0.0027	No
343	DDC	670408	18510	-4.130	0.0058	No