Details for gene set ET743_SARCOMA

Table: GSEA Results Summary

Dataset	Set_03_absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls #truncNotch_versus_absentNotch
Phenotype	phenotype_absentNotch_versus_truncNotch.cls#truncNotch_versus_absentNotch
Upregulated in class	absentNotch
GeneSet	ET743_SARCOMA_DN
Enrichment Score (ES)	-0.60348445
Normalized Enrichment Score (NES)	-1.8366879
Nominal p-value	0.0
FDR q-value	0.007020734
FWER p-Value	0.043

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	WNT5B	5080162	71	4.385	0.0163	No
2	MID1IP1	2570739	499	2.723	0.0057	No
3	BUB3	3170546	627	2.521	0.0104	No
4	HIST1H4B	4210524	760	2.317	0.0139	No
5	HSPA8	2120315 1050132 6550746	930	2.090	0.0144	No
6	ARPC5L	1090148	956	2.061	0.0225	No
7	HIST1H4C	5570528	957	2.061	0.0320	No
8	LHFPL2	450020	1124	1.894	0.0317	No
9	UBE2C	6130017	1159	1.873	0.0385	No
10	ZDHHC16	4230390	1319	1.722	0.0378	No
11	RBM14	5340731 5690315	1352	1.692	0.0438	No
12	ARFGAP1	4780364 5390358	1370	1.676	0.0506	No
13	BAG2	2900324	1539	1.540	0.0486	No
14	SLC2A1	2100609	1676	1.465	0.0480	No
15	PANX1	6550632	1758	1.406	0.0501	No
16	SON	3120148 5860239 7040403	1865	1.303	0.0503	No
17	ARHGEF2	3360577	1901	1.274	0.0543	No
18	TARDBP	870390 2350093	2211	1.070	0.0424	No
19	KIAA0859	510497 770722 1340687 6840711	2414	0.963	0.0359	No
20	DNAJA2	2630253 6860358	2415	0.960	0.0403	No
21	ADSL	5570484	2502	0.908	0.0398	No
22	SFRS9	3800047	2527	0.890	0.0426	No
23	TOP1	770471 4060632 6650324	2641	0.831	0.0403	No
24	PSMC2	7040010	2866	0.707	0.0314	No
25	PSMA5	5390537	3139	0.596	0.0194	No
26	PKN2	940746 2350168	3193	0.577	0.0192	No
27	DLG5	450215	3210	0.570	0.0209	No
28	MTMR4	4540524	3460	0.484	0.0096	No
29	EIF3S10	1190079 3840176	3518	0.465	0.0087	No
30	ERCC3	6900008	3556	0.456	0.0088	No
31	UBN1	5900195	3575	0.451	0.0099	No
32	ANLN	1780113 2470537 6840047	3777	0.399	0.0008	No
33	FADD	2360593 4210692 6520019	3820	0.392	0.0003	No
34	JMJD2B	6350372 6400471	3840	0.387	0.0011	No
35	EGFR	4920138 6480521	4005	0.351	-0.0062	No
36	SNIP1	5360092	4165	0.323	-0.0133	No
37	BLZF1	630088	4177	0.321	-0.0125	No
38	PHF6	3120632 3990041	4227	0.313	-0.0137	No
39	RNF14	50402 1340041 6370687	4287	0.302	-0.0155	No
40	PDGFB	3060440 6370008	4904	0.217	-0.0479	No
41	HSPE1	3170438	4965	0.210	-0.0502	No
42	BUB1	5390270	5073	0.197	-0.0551	No
43	PLAG1	1450142 3870139 6520039	5097	0.194	-0.0555	No
44	CORO1C	4570397	5174	0.186	-0.0587	No
45	HS3ST3B1	380040	5372	0.169	-0.0687	No
46	CRSP6	2940358	5637	0.150	-0.0823	No
47	RCC1	2480358	5687	0.146	-0.0843	No
48	PLK1	1780369 2640121	5726	0.143	-0.0857	No
49	OSBP	5390471	5823	0.136	-0.0903	No
50	B4GALT5	1230692	5916	0.129	-0.0947	No
51	NUFIP1	6350241	6438	0.100	-0.1225	No
52	NBN	730538 2470619 4780594	6543	0.095	-0.1277	No
53	THRAP3	6180309	6878	0.082	-0.1455	No
54	NMI	520270	6971	0.079	-0.1501	No
55	JMJD1C	940575 2120025	7022	0.077	-0.1524	No
56	RBM27	4050603	7059	0.076	-0.1540	No
57	CXXC5	840010	7155	0.073	-0.1589	No
58	TDG	2900358 2940079	7217	0.071	-0.1619	No
59	USP8	2640347 3840451 6100672	7235	0.070	-0.1625	No
60	PRKD3	5220520 5890519	7355	0.066	-0.1686	No
61	MRPL1	430626 3130129 5220152	7358	0.066	-0.1684	No
62	CDK7	2640451	7569	0.060	-0.1795	No
63	TRIP4	630072	7580	0.060	-0.1798	No
64	IPO7	2190746	7698	0.057	-0.1859	No
65	CDH11	1230133 2100180 4610110	7772	0.055	-0.1896	No
66	FBXL7	6620711	7955	0.051	-0.1992	No
67	FZD1	3140215	8078	0.048	-0.2056	No
68	GTF2H1	2570746 2650148	8154	0.047	-0.2095	No
69	FOSL1	430021	8299	0.043	-0.2171	No
70	TRIM24	7050670	8765	0.034	-0.2422	No
71	NPAS2	770670	8767	0.033	-0.2421	No
72	MAPKAPK5	2510601	8785	0.033	-0.2429	No
73	SMARCA5	6620050	8953	0.030	-0.2518	No
74	ATF1	4570142 5550095	8997	0.029	-0.2540	No
75	MTIF2	2260270	9041	0.028	-0.2562	No
76	NCOA6	1780333 6450110	9071	0.027	-0.2577	No
77	CTGF	4540577	9479	0.020	-0.2797	No
78	JAG1	3440390	9767	0.015	-0.2952	No
79	EPS8	7050204	9837	0.014	-0.2989	No
80	SAMD4A	1170717	10258	0.007	-0.3216	No
81	MAP3K4	5720041	10292	0.006	-0.3234	No
82	KIF11	5390139	10668	0.000	-0.3437	No
83	XRCC5	7100286	10724	-0.001	-0.3467	No
84	TIAM2	360195	10839	-0.003	-0.3529	No
85	EPS15	4200215	10846	-0.003	-0.3532	No
86	CRK	1230162 4780128	10922	-0.004	-0.3573	No
87	BIRC6	70148	10935	-0.004	-0.3579	No
88	ATG5	6200433 5360324	11030	-0.006	-0.3630	No
89	MFAP1	6660092	11338	-0.011	-0.3796	No
90	SPRY2	5860184	11448	-0.014	-0.3854	No
91	RAB5A	6520324	11473	-0.014	-0.3867	No
92	VEGFC	5910494	11694	-0.018	-0.3985	No
93	RAB6A	3840463 4780731	11950	-0.023	-0.4123	No
94	CFLAR	2320605 6180440	12498	-0.036	-0.4418	No
95	CDC25C	2570673 4760161 6520707	12613	-0.040	-0.4478	No
96	CSNK2A1	1580577	12809	-0.045	-0.4582	No
97	GDI2	2370068	12910	-0.048	-0.4634	No
98	CDC42BPA	840671	12955	-0.050	-0.4655	No
99	GOPC	6620400	13245	-0.060	-0.4810	No
100	CYHR1	940609 2810463 3190332 3290692 4280411	13267	-0.061	-0.4818	No
101	RAD23B	2190671	13382	-0.065	-0.4877	No
102	ACSL3	3140195	13515	-0.072	-0.4945	No
103	GGPS1	840128 2320215	13632	-0.077	-0.5005	No
104	RCOR1	5360717	13706	-0.082	-0.5041	No
105	HSPA1L	4010538	13779	-0.087	-0.5076	No
106	FYN	2100468 4760520 4850687	13831	-0.091	-0.5099	No
107	SSFA2	3870133	13843	-0.091	-0.5101	No
108	PTPRK	1450433 2640142	14037	-0.106	-0.5201	No
109	PAFAH2	3140451 5720593 6510014	14368	-0.141	-0.5373	No
110	PSMB1	2940402	14659	-0.186	-0.5522	No
111	CDC23	3190593	14662	-0.186	-0.5515	No
112	MRPS35	2370603 4070551	14766	-0.207	-0.5561	No
113	LUZP1	940075 4280458 6180070	14789	-0.213	-0.5563	No
114	ARFGEF2	5550500	14812	-0.216	-0.5565	No
115	FNDC3A	2690097 3290044	14981	-0.255	-0.5645	No
116	USP12	6130735 6620280	15158	-0.309	-0.5726	No
117	FAF1	2450717 2510121 4730156	15181	-0.315	-0.5724	No
118	WEE1	3390070	15186	-0.317	-0.5711	No
119	MYC	380541 4670170	15244	-0.337	-0.5727	No
120	FBXL3	5910142	15350	-0.371	-0.5766	No
121	EML4	5700373	15414	-0.390	-0.5783	No
122	STK17B	130091	15418	-0.393	-0.5766	No
123	SRRM2	2940746 6350253	15524	-0.428	-0.5803	No
124	CCNA2	5290075	15560	-0.440	-0.5802	No
125	GABPB2	6130450 7050735	15566	-0.444	-0.5784	No
126	BIRC2	2940435 4730020	15732	-0.505	-0.5851	No
127	BCL2L1	1580452 4200152 5420484	15795	-0.530	-0.5860	No
128	CLCN7	2970095	15849	-0.555	-0.5863	No
129	XBP1	3840594	15872	-0.564	-0.5849	No
130	TCERG1	2350551 4540397 5220746	15978	-0.615	-0.5878	No
131	MCM3	5570068	16006	-0.627	-0.5864	No
132	PSMC6	2810021	16287	-0.776	-0.5980	No
133	GTF2B	6860685	16353	-0.810	-0.5978	No
134	CDK5R1	3870161	16378	-0.826	-0.5953	No
135	YWHAE	5310435	16530	-0.911	-0.5993	Yes
136	TNFSF5IP1	2060095	16550	-0.929	-0.5960	Yes
137	MAT2A	4070026 4730079 6020280	16565	-0.938	-0.5925	Yes
138	PPP1CC	6380300 2510647	16673	-0.993	-0.5937	Yes
139	AURKA	780537	16736	-1.026	-0.5924	Yes
140	CDC5L	3130446 3390025 6400204	16764	-1.043	-0.5890	Yes
141	ELOVL6	5340746	16791	-1.064	-0.5855	Yes
142	PRIM2A	7000692	16825	-1.081	-0.5823	Yes
143	SIRPA	130465 5700332	16863	-1.108	-0.5792	Yes
144	MRPL15	360390	16881	-1.128	-0.5750	Yes
145	PSME3	2810537	16929	-1.158	-0.5722	Yes
146	USP3	2060332	16935	-1.162	-0.5671	Yes
147	SUPV3L1	1170072	17004	-1.229	-0.5651	Yes
148	PJA2	430537	17072	-1.296	-0.5628	Yes
149	RIPK1	3190025	17073	-1.297	-0.5568	Yes
150	OGT	2360131 4610333	17074	-1.298	-0.5509	Yes
151	RBM17	870592	17191	-1.417	-0.5506	Yes
152	CRLF3	6620019	17202	-1.430	-0.5446	Yes
153	TXNRD1	6590446	17271	-1.508	-0.5413	Yes
154	UBE2D3	3190452	17364	-1.609	-0.5389	Yes
155	NET1	2900707	17388	-1.643	-0.5326	Yes
156	SIRT1	1190731	17426	-1.676	-0.5269	Yes
157	TOP2A	360717	17451	-1.703	-0.5204	Yes
158	MCTS1	6130133	17468	-1.732	-0.5132	Yes
159	MAPK14	5290731	17476	-1.736	-0.5056	Yes
160	STAU1	2320494	17504	-1.767	-0.4990	Yes
161	FNTA	70059	17541	-1.808	-0.4926	Yes
162	RABGGTB	3120037	17731	-2.067	-0.4933	Yes
163	ZDHHC5	1690711	17740	-2.080	-0.4842	Yes
164	EIF4B	5390563 5270577	17772	-2.116	-0.4761	Yes
165	BTG1	4200735 6040131 6200133	17833	-2.195	-0.4693	Yes
166	PPP2R5E	70671 2120056	17840	-2.202	-0.4595	Yes
167	UBE2D2	4590671 6510446	17855	-2.229	-0.4500	Yes
168	SFRS3	770315 4230593	17869	-2.240	-0.4403	Yes
169	OSBPL9	2570373	17913	-2.316	-0.4320	Yes
170	MAP3K7	6040068	17946	-2.361	-0.4229	Yes
171	POLD3	6400278	18117	-2.715	-0.4196	Yes
172	AOF2	2060300	18188	-2.857	-0.4102	Yes
173	DDX21	6100446	18207	-2.918	-0.3978	Yes
174	PSMA4	4560427	18265	-3.059	-0.3868	Yes
175	PCNA	940754	18279	-3.090	-0.3733	Yes
176	RABGAP1	5050397	18290	-3.128	-0.3594	Yes
177	SLC25A17	2100369	18292	-3.137	-0.3450	Yes
178	PSMD14	5690593	18299	-3.166	-0.3308	Yes
179	TBK1	5690338	18325	-3.258	-0.3171	Yes
180	DCK	6900411	18333	-3.283	-0.3024	Yes
181	RAB1A	2370671	18364	-3.405	-0.2883	Yes
182	CCNH	3190347	18401	-3.563	-0.2739	Yes
183	RAP1B	3710138	18463	-3.825	-0.2596	Yes
184	CCT4	6380161	18499	-4.044	-0.2428	Yes
185	GTF2H2	5130358	18509	-4.126	-0.2243	Yes
186	SRPK2	6380341	18529	-4.282	-0.2056	Yes
187	HSPH1	1690017	18532	-4.292	-0.1860	Yes
188	DDX20	3290348	18537	-4.358	-0.1661	Yes
189	TMPO	4050494	18542	-4.448	-0.1459	Yes
190	RPP14	7040014	18550	-4.485	-0.1256	Yes
191	SLC4A1AP	3190576	18566	-4.754	-0.1045	Yes
192	EP400	3940722	18591	-5.156	-0.0821	Yes
193	HDAC2	4050433	18596	-5.359	-0.0576	Yes
194	PRKACB	4210170	18607	-6.062	-0.0302	Yes
195	LBR	4540671	18614	-6.656	0.0001	Yes